List of works - Stephan Herzig

11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice

scientific article

A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice

scientific article

Adipose tissue: between the extremes.

scientific article

Aging-Dependent Reduction in Glyoxalase 1 Delays Wound Healing

scientific article published on 22 June 2013

An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice

scientific article published on 29 August 2016

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia

scientific article published on 26 November 2015

Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex

scientific article

Brown adipose tissue harbors a distinct sub-population of regulatory T cells

scientific article

Brown and white fat: from signaling to disease

scientific article published on 01 May 2013

Brown fat develops a brite future

scientific article published on 22 December 2012

Browning of white adipose tissue uncouples glucose uptake from insulin signaling

scientific article (publication date: 2014)

CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma

scientific article published on November 2003

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

scientific article (publication date: 13 September 2001)

Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors

article

Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression

scientific article

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

scientific article published on 05 March 2021

Common pathological processes and transcriptional pathways in Alzheimer's disease and type 2 diabetes

scientific article published on January 2009

Compromised DNA repair is responsible for diabetes-associated fibrosis

scientific article published on 27 April 2020

Control of adipose tissue inflammation through TRB1.

scientific article

Corrigendum

scholarly article published in EMBO Molecular Medicine

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

scientific article

Detecting endogenous SUMO targets in mammalian cells and tissues

scientific article

Discovering orphans' sweet secret: NR4A receptors and hepatic glucose production

scientific article published on November 2006

Effect of metformin on methylglyoxal metabolism in patients with type 2 diabetes

scientific article published on 7 April 2014

Endothelial Notch signaling controls insulin transport in muscle

scientific article published on 18 March 2020

Energy metabolism in cachexia

scientific article published on 19 March 2019

Erratum: correction: A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

scientific article published in Nature

Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health

scientific article published on 03 May 2016

Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype

scientific journal article

Glucocorticoid hormones and energy homeostasis

scientific article published in August 2014

Glucocorticoids, metabolism and metabolic diseases.

scientific article

Hematopoietic Kit Deficiency, rather than Lack of Mast Cells, Protects Mice from Obesity and Insulin Resistance

scientific article published on May 2015

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia

scientific article published in April 2011

Hepatic transforming growth factor-β 1 stimulated clone-22 D1 controls systemic cholesterol metabolism

scientific article published on 08 January 2014

Heterodimeric Pbx-Prep1 homeodomain protein binding to the glucagon gene restricting transcription in a cell type-dependent manner.

scientific article published on September 2000

High levels of modified ceramides are a defining feature of murine and human cancer cachexia

scientific article published on 08 October 2020

How Do Glucocorticoids Regulate Lipid Metabolism?

scientific article

Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion

scientific article

IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.

scientific article published on 14 January 2016

Immune cells and metabolic dysfunction

scientific article

In vivo assessment of cold stimulation effects on the fat fraction of brown adipose tissue using DIXON MRI.

scientific article

In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice

scientific article published in December 2009

Let's burn whatever you have: mitofusin 2 metabolically re-wires brown adipose tissue

scientific article

Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice

scientific article published on 02 February 2009

Liver: A Target of Late Diabetic Complications ⬇️

scientific article published on 08 March 2012

Mesoderm-specific transcript (MEST) is a negative regulator of human adipocyte differentiation

scientific article

Metabolic control through glucocorticoid hormones: an update

scientific article published on 20 March 2013

Mice lacking neutral amino acid transporter B(0)AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control

scientific article published on 16 February 2015

MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes

scientific article published on 01 June 2014

Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor.

scientific article published in July 2011

Molecular regulation of urea cycle function by the liver glucocorticoid receptor

scientific article

Mouse redox histology using genetically encoded probes

scientific article published on 15 March 2016

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.

scientific article published on 16 January 2012

Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice

scientific article

PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation

scientific article

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

scientific article published on 25 April 2004

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis

scientific article (publication date: October 2015)

PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity

scientific article published on January 2014

Pancreatic cancer microenvironment

scientific article published on August 2007

Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL

scientific article

Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis

scientific article published in December 2009

Role of glucocorticoids and the glucocorticoid receptor in metabolism: insights from genetic manipulations.

scientific article

Selective enrichment of newly synthesized proteins for quantitative secretome analysis

scientific article

Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1

scientific journal article

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

scientific article

TSC22D4 is a molecular output of hepatic wasting metabolism

scientific article

The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.

scientific article published in September 2008

The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis

scientific article published on 26 September 2019

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

scientific article

The ω6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway.

scientific article

Thermogenic adipocytes: from cells to physiology and medicine

scientific article

Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy

scientific article

Transcriptional co-factors and hepatic energy metabolism

scientific article

Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue

scientific journal article

Transcriptional regulation of plasminogen activator inhibitor-1 expression by insulin-like growth factor-1 via MAP kinases and hypoxia-inducible factor-1 in HepG2 cells

scientific article published on 01 June 2005

White and brown adipose stem cells: from signaling to clinical implications

scientific article

[Diabetes and the liver]

scientific article published on 29 May 2013

[Transcription factors and metabolic diseases]

scientific article published on 01 May 2007

daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans

scientific article

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

scientific article

List of works by Stephan Herzig

11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice

A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice

Adipose tissue: between the extremes.

Aging-Dependent Reduction in Glyoxalase 1 Delays Wound Healing

An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia

Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex

Brown adipose tissue harbors a distinct sub-population of regulatory T cells

Brown and white fat: from signaling to disease

Brown fat develops a brite future

Browning of white adipose tissue uncouples glucose uptake from insulin signaling

CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors

Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

Common pathological processes and transcriptional pathways in Alzheimer's disease and type 2 diabetes

Compromised DNA repair is responsible for diabetes-associated fibrosis

Control of adipose tissue inflammation through TRB1.

Corrigendum

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

Detecting endogenous SUMO targets in mammalian cells and tissues

Discovering orphans' sweet secret: NR4A receptors and hepatic glucose production

Effect of metformin on methylglyoxal metabolism in patients with type 2 diabetes

Endothelial Notch signaling controls insulin transport in muscle

Energy metabolism in cachexia

Erratum: correction: A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health

Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype

Glucocorticoid hormones and energy homeostasis

Glucocorticoids, metabolism and metabolic diseases.

Hematopoietic Kit Deficiency, rather than Lack of Mast Cells, Protects Mice from Obesity and Insulin Resistance

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia

Hepatic transforming growth factor-β 1 stimulated clone-22 D1 controls systemic cholesterol metabolism

Heterodimeric Pbx-Prep1 homeodomain protein binding to the glucagon gene restricting transcription in a cell type-dependent manner.

High levels of modified ceramides are a defining feature of murine and human cancer cachexia

How Do Glucocorticoids Regulate Lipid Metabolism?

Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion

IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin.

Immune cells and metabolic dysfunction

In vivo assessment of cold stimulation effects on the fat fraction of brown adipose tissue using DIXON MRI.

In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice

Let's burn whatever you have: mitofusin 2 metabolically re-wires brown adipose tissue

Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice

Liver: A Target of Late Diabetic Complications ⬇️

Mesoderm-specific transcript (MEST) is a negative regulator of human adipocyte differentiation

Metabolic control through glucocorticoid hormones: an update

Mice lacking neutral amino acid transporter B(0)AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control

MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes

Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor.

Molecular regulation of urea cycle function by the liver glucocorticoid receptor

Mouse redox histology using genetically encoded probes

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.

Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice

PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis

PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity

Pancreatic cancer microenvironment

Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL

Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis

Role of glucocorticoids and the glucocorticoid receptor in metabolism: insights from genetic manipulations.

Selective enrichment of newly synthesized proteins for quantitative secretome analysis

Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

TSC22D4 is a molecular output of hepatic wasting metabolism

The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.

The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

The ω6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway.

Thermogenic adipocytes: from cells to physiology and medicine

Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy

Transcriptional co-factors and hepatic energy metabolism

Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue

Transcriptional regulation of plasminogen activator inhibitor-1 expression by insulin-like growth factor-1 via MAP kinases and hypoxia-inducible factor-1 in HepG2 cells

White and brown adipose stem cells: from signaling to clinical implications

[Diabetes and the liver]

[Transcription factors and metabolic diseases]

daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans