List of works - Cristina Airoldi

(1)H NMR To Explore the Metabolome of Exhaled Breath Condensate in α1-Antitrypsin Deficient Patients: A Pilot Study

scientific article

1H NMR To Evaluate the Metabolome of Bronchoalveolar Lavage Fluid (BALf) in Bronchiolitis Obliterans Syndrome (BOS): Toward the Development of a New Approach for Biomarker Identification

scientific article

Aminated Sugars, Synthesis, and Biological Activity

Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models

scientific article published on 01 January 2019

Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control.

scientific article

Arabinose 5-phosphate isomerase as a target for antibacterial design: studies with substrate analogues and inhibitors.

scientific article published on 11 August 2013

Aβ Monomers, Oligomers and Fibrils: Structural Features

article published in 2011

Beta amyloid aggregation inhibitors: small molecules as candidate drugs for therapy of Alzheimer's disease

scientific article

Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry

scientific article

Carbohydrate scaffolds in chemical genetic studies

scientific article published on 17 June 2009

Cis-Glyco-Fused Benzopyran Derivatives as Hit Compounds for the Development of Therapeutic and Diagnostic Tools against Neurodegenerative Diseases

article

Coffee variety, origin and extraction procedure: Implications for coffee beneficial effects on human health

scientific article published on 12 November 2018

Curcumin derivatives as new ligands of Aβ peptides

scientific article published on December 2010

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors

scientific article published on October 2005

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors.

scientific article

Effectiveness of Vigna unguiculata seed extracts in preventing colorectal cancer

scientific article published on 26 June 2020

Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK.

scientific article published on 2 April 2015

Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model

scientific article published on 15 June 2017

Exploiting the therapeutic potential of 8-β-d-glucopyranosylgenistein: synthesis, antidiabetic activity, and molecular interaction with islet amyloid polypeptide and amyloid β-peptide (1-42).

scientific article published on 12 November 2014

Flavonoids and Their Glycosides as Anti-amyloidogenic Compounds: Aβ1-42 Interaction Studies to Gain New Insights into Their Potential for Alzheimer's Disease Prevention and Therapy

scientific article

Flavonoids in the treatment of Alzheimer's and other neurodegenerative diseases

scientific article published on 9 February 2018

Fluorescent amyloid β-peptide ligand derivatives as potential diagnostic tools for Alzheimer’s disease

From cancer metabolism to new biomarkers and drug targets

scientific article published on 23 July 2011

Fructose-Based Proline Analogues: Exploring the Prolyl trans/cis-Amide Rotamer Population in Model Peptides

article

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

scientific article published on 13 August 2007

Glycan Carriers As Glycotools for Medicinal Chemistry Applications

scientific article published on 01 January 2019

Glycoconjugates in cancer therapy.

scientific article published on January 2008

Green and Roasted Coffee Extracts Inhibit Interferon-β Release in LPS-Stimulated Human Macrophages

scientific article published on 05 May 2022

HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders

scientific article published on 4 September 2017

How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode

scientific article published on 5 November 2015

Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model

scientific article published on 27 October 2018

Methionine supplementation stimulates mitochondrial respiration

scientific article published on 02 October 2018

NMR Molecular Recognition Studies for the Elucidation of Protein and Nucleic Acid Structure and Function

scientific article published on 9 February 2015

NMR analysis of budding yeast metabolomics: a rapid method for sample preparation

scientific article published in 2015

Nanoliposomes presenting on surface a cis-glycofused benzopyran compound display binding affinity and aggregation inhibition ability towards Amyloid β1-42 peptide.

scientific article published on 24 July 2014

Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins.

scientific article

Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR.

scientific article published on 9 January 2013

Natural compounds against neurodegenerative diseases: molecular characterization of the interaction of catechins from green tea with Aβ1-42, PrP106-126, and ataxin-3 oligomers.

scientific article published in September 2014

Natural glycoconjugates with antitumor activity

scientific article

New targets for antibacterial design: Kdo biosynthesis and LPS machinery transport to the cell surface.

scientific article published on January 2011

Performance Assessment in Fingerprinting and Multi Component Quantitative NMR Analyses

scientific article

Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis

scientific article

Pyrrolo[2,1-c][1,4]benzodiazepine as a scaffold for the design and synthesis of anti-tumour drugs.

scientific article published on January 2009

Re LPS Biogenetic Pathway: Enzyme Characterisation and Synthetic Efforts Towards Inhibitors

scientific article published in May 2008

Saturation Transfer Difference NMR Experiments of Membrane Proteins in Living Cells under HR-MAS Conditions: The Interaction of the SGLT1 Co-transporter with Its Ligands

scientific article published on 27 October 2011

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).

scientific article

Solid-phase supported mimic of GDP-l-galactose

Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin

scientific article published on 29 October 2020

Structural Modifications of cis-Glycofused Benzopyran Compounds and Their Influence on the Binding to Amyloid-β Peptide.

scientific article

Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.

scientific article published in March 2018

Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors

scientific article published on March 2010

Sugar-based enantiomeric and conformationally constrained pyrrolo[2,1-c][1,4]-benzodiazepines as potential GABAA ligands

scientific article

Synthesis and biological evaluation of a small library of nojirimycin-derived bicyclic iminosugars

scientific article

Synthesis and biological evaluation of arabinose 5-phosphate mimics modified at position five.

scientific article

Synthesis of 3-Deoxy-d-threopentofuranose 5-Phosphate, a Substrate of Arabinose 5-Phosphate Isomerase

scientific article published on 14 January 2010

Synthesis, Molecular Modeling and Biological Evaluation of Metabolically Stable Analogues of the Endogenous Fatty Acid Amide Palmitoylethanolamide

scientific article published on 28 November 2020

Targeting Bacterial Biofilm: A New LecA Multivalent Ligand with Inhibitory Activity

scientific article published on 24 September 2019

Targeting Bacterial Membranes: Identification of Pseudomonas aeruginosaD-Arabinose-5P Isomerase and NMR Characterisation of its Substrate Recognition and Binding Properties

scientific article published on 17 February 2011

Targeting bacterial membranes: NMR spectroscopy characterization of substrate recognition and binding requirements of D-arabinose-5-phosphate isomerase

scientific article

Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.

scientific article

The Kdo biosynthetic pathway toward OM biogenesis as target in antibacterial drug design and development

scientific article published on March 2009

The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins

scientific article (publication date: 2011)

Towards a Universal Approach Based on Omics Technologies for the Quality Control of Food

scientific article

Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect

scientific article published on 18 May 2021

Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's disease.

scientific article

cis-Glyco-fused benzopyran compounds as new amyloid-β peptide ligands ⬇️

scientific article published on August 22, 2011

List of works by Cristina Airoldi

(1)H NMR To Explore the Metabolome of Exhaled Breath Condensate in α1-Antitrypsin Deficient Patients: A Pilot Study

1H NMR To Evaluate the Metabolome of Bronchoalveolar Lavage Fluid (BALf) in Bronchiolitis Obliterans Syndrome (BOS): Toward the Development of a New Approach for Biomarker Identification

Aminated Sugars, Synthesis, and Biological Activity

Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models

Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control.

Arabinose 5-phosphate isomerase as a target for antibacterial design: studies with substrate analogues and inhibitors.

Aβ Monomers, Oligomers and Fibrils: Structural Features

Beta amyloid aggregation inhibitors: small molecules as candidate drugs for therapy of Alzheimer's disease

Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry

Carbohydrate scaffolds in chemical genetic studies

Cis-Glyco-Fused Benzopyran Derivatives as Hit Compounds for the Development of Therapeutic and Diagnostic Tools against Neurodegenerative Diseases

Coffee variety, origin and extraction procedure: Implications for coffee beneficial effects on human health

Curcumin derivatives as new ligands of Aβ peptides

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors.

Effectiveness of Vigna unguiculata seed extracts in preventing colorectal cancer

Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK.

Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model

Exploiting the therapeutic potential of 8-β-d-glucopyranosylgenistein: synthesis, antidiabetic activity, and molecular interaction with islet amyloid polypeptide and amyloid β-peptide (1-42).

Flavonoids and Their Glycosides as Anti-amyloidogenic Compounds: Aβ1-42 Interaction Studies to Gain New Insights into Their Potential for Alzheimer's Disease Prevention and Therapy

Flavonoids in the treatment of Alzheimer's and other neurodegenerative diseases

Fluorescent amyloid β-peptide ligand derivatives as potential diagnostic tools for Alzheimer’s disease

From cancer metabolism to new biomarkers and drug targets

Fructose-Based Proline Analogues: Exploring the Prolyl trans/cis-Amide Rotamer Population in Model Peptides

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

Glycan Carriers As Glycotools for Medicinal Chemistry Applications

Glycoconjugates in cancer therapy.

Green and Roasted Coffee Extracts Inhibit Interferon-β Release in LPS-Stimulated Human Macrophages

HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders

How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode

Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model

Methionine supplementation stimulates mitochondrial respiration

NMR Molecular Recognition Studies for the Elucidation of Protein and Nucleic Acid Structure and Function

NMR analysis of budding yeast metabolomics: a rapid method for sample preparation

Nanoliposomes presenting on surface a cis-glycofused benzopyran compound display binding affinity and aggregation inhibition ability towards Amyloid β1-42 peptide.

Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins.

Natural compounds against Alzheimer's disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMR.

Natural compounds against neurodegenerative diseases: molecular characterization of the interaction of catechins from green tea with Aβ1-42, PrP106-126, and ataxin-3 oligomers.

Natural glycoconjugates with antitumor activity

New targets for antibacterial design: Kdo biosynthesis and LPS machinery transport to the cell surface.

Performance Assessment in Fingerprinting and Multi Component Quantitative NMR Analyses

Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis

Pyrrolo[2,1-c][1,4]benzodiazepine as a scaffold for the design and synthesis of anti-tumour drugs.

Re LPS Biogenetic Pathway: Enzyme Characterisation and Synthetic Efforts Towards Inhibitors

Saturation Transfer Difference NMR Experiments of Membrane Proteins in Living Cells under HR-MAS Conditions: The Interaction of the SGLT1 Co-transporter with Its Ligands

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).

Solid-phase supported mimic of GDP-l-galactose

Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin

Structural Modifications of cis-Glycofused Benzopyran Compounds and Their Influence on the Binding to Amyloid-β Peptide.

Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.

Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors

Sugar-based enantiomeric and conformationally constrained pyrrolo[2,1-c][1,4]-benzodiazepines as potential GABAA ligands

Synthesis and biological evaluation of a small library of nojirimycin-derived bicyclic iminosugars

Synthesis and biological evaluation of arabinose 5-phosphate mimics modified at position five.

Synthesis of 3-Deoxy-d-threopentofuranose 5-Phosphate, a Substrate of Arabinose 5-Phosphate Isomerase

Synthesis, Molecular Modeling and Biological Evaluation of Metabolically Stable Analogues of the Endogenous Fatty Acid Amide Palmitoylethanolamide

Targeting Bacterial Biofilm: A New LecA Multivalent Ligand with Inhibitory Activity

Targeting Bacterial Membranes: Identification of Pseudomonas aeruginosaD-Arabinose-5P Isomerase and NMR Characterisation of its Substrate Recognition and Binding Properties

Targeting bacterial membranes: NMR spectroscopy characterization of substrate recognition and binding requirements of D-arabinose-5-phosphate isomerase

Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.

The Kdo biosynthetic pathway toward OM biogenesis as target in antibacterial drug design and development

The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins

Towards a Universal Approach Based on Omics Technologies for the Quality Control of Food

Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect

Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's disease.

cis-Glyco-fused benzopyran compounds as new amyloid-β peptide ligands ⬇️