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List of works by Elena Miranda

A novel interaction between aging and ER overload in a protein conformational dementia

scientific article published on 18 January 2013

A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency.

scientific article

ANCA-associated vasculitis is linked to carriage of the Z allele of 1 antitrypsin and its polymers

scientific article published on 05 August 2011

Analysis and quantification of the secretory products of the subcommissural organ by use of monoclonal antibodies

scientific article published in March 2001

Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke

scientific article

B-type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways

scientific article published on December 2003

Characterisation of serpin polymers in vitro and in vivo.

scientific article

Circulating polymers in 1-antitrypsin deficiency

scientific article published on 06 March 2014

Continuous delivery of a monoclonal antibody against Reissner's fiber into CSF reveals CSF-soluble material immunorelated to the subcommissural organ in early chick embryos.

scientific article

Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of α1-Antitrypsin: Implications for Disease and Drug Design

scientific article

Defining the mechanism of polymerization in the serpinopathies

scientific article

Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors

scientific article published on 11 July 2020

Endoplasmic reticulum dysfunction in neurological disease

scientific article published on January 2013

Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency

scientific article published on 14 March 2013

Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins

scientific article

Evaluation of Full-length, Cleaved and Nitrosylated Serum Surfactant Protein D as Biomarkers for COPD

scientific article published on 01 April 2011

Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage

scientific article published on 01 March 2007

Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F.

scientific article published on 27 June 2014

Glycosylation Tunes Neuroserpin Physiological and Pathological Properties

scientific article published on 03 May 2020

Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum

scientific article published on 14 September 2015

Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

scientific article

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

scientific article

Molecular characterization of the new defective P(brescia) alpha1-antitrypsin allele.

scientific article published in August 2009

Molecular mousetraps and the serpinopathies

scientific article published in April 2005

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

scientific article

Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum

scientific article

Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

scientific article published on 07 May 2009

Neuroserpin: a serpin to think about

scientific article

Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker

scientific article

Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies.

scientific article published on 29 August 2007

Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies

scientific article published on March 2004

Quantification of the secretory glycoproteins of the subcommissural organ by a sensitive sandwich ELISA with a polyclonal antibody and a set of monoclonal antibodies against the bovine Reissner's fiber.

scientific article published in December 1998

Rostral floor plate (flexural organ) secretes glycoproteins immunologically similar to subcommissural organ glycoproteins in dogfish (Scyliorhinus canicula) embryos

scientific article published in August 1997

Searching for specific binding sites of the secretory glycoproteins of the subcommissural organ

scientific article published in March 2001

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

scientific article

Targeting serpins in high-throughput and structure-based drug design

scientific article

The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency.

scientific article

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.

scientific article published on 11 February 2008

The molecular species responsible for α1 -antitrypsin deficiency are suppressed by a small molecule chaperone

scientific article published on 15 October 2020

The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome

scientific article published on 21 December 2010

The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization

scientific article

The serpinopathies studying serpin polymerization in vivo

scientific article

Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization.

scientific article

alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies

scientific article published on 14 May 2009

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