Search filters

List of works by Kevin M Ryan

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

scientific article published on 8 March 2007

Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.

scientific article

Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy

scientific article

Analysis of E-box DNA binding during myeloid differentiation reveals complexes that contain Mad but not Max.

scientific article published on July 1997

Analysis of macroautophagy by immunohistochemistry

scientific article published on 7 May 2012

Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

scientific article published on 9 September 2010

Autophagy and cancer

scientific article published on January 2012

Autophagy and cancer--issues we need to digest.

scientific article published on 28 May 2012

Autophagy chews Fap to promote apoptosis

scientific article published on 01 January 2014

Autophagy in malignant transformation and cancer progression

scientific article

Autophagy in tumour cell death

scientific article published on 14 June 2013

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

scientific article published on 01 January 2018

Autophagy, the innate immune response and cancer

scientific article published on 03 August 2020

Autophagy: an adaptable modifier of tumourigenesis

scientific article published on 18 January 2010

Cancer: Viruses' backup plan

scientific article published in August 2010

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

scientific article published on 01 October 1998

Cell-cycle progression is not essential for c-Myc to block differentiation

scientific article published on June 1997

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

scientific article

DNA-binding independent cell death from a minimal proapoptotic region of E2F-1.

scientific article published on May 2006

DRAM links autophagy to p53 and programmed cell death

scientific article

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

scientific article (publication date: 14 July 2006)

DRAM-1 encodes multiple isoforms that regulate autophagy

scientific article

DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose

scientific article published on May 2015

Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells

scientific journal article

Does androgen-ablation therapy (AAT) associated autophagy have a pro-survival effect in LNCaP human prostate cancer cells?

scientific article published on 16 August 2012

E2F1 drives chemotherapeutic drug resistance via ABCG2.

scientific article

Emerging roles of transcriptional programs in autophagy regulation

scientific article published on 5 October 2017

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy

scientific article published on 05 January 2010

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

scientific article published on 18 April 2013

Glucose-starved cells do not engage in prosurvival autophagy

scientific article published on 6 September 2013

Growth factor signaling permits hypoxia-induced autophagy by a HIF1α-dependent, BNIP3/3L-independent transcriptional program in human cancer cells

scientific article published on 13 October 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

Hemizygosity of the MAX Gene Locus in HL60 Cells

article

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity

scientific article

Hzf and hCAS/CSE1L: making the right choice in p53-mediated tumour suppression

scientific article published on 01 October 2007

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

scientific article published on 31 May 2012

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

scientific article published on July 1997

Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions

scientific article published in June 2001

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

scientific article published on 15 May 2012

Involvement of RNA Polymerase III in Immune Responses.

scientific article published on 16 March 2015

Life and death decisions by E2F-1.

scientific article published on February 2004

Loss of autophagy causes a synthetic lethal deficiency in DNA repair.

scientific article

Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.

scientific article published in July 2004

Lysosomal proteins in cell death and autophagy

scientific article

MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity

scientific journal article

Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells.

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Myc oncogenes: the enigmatic family

scientific article

New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy

scientific article published on 06 February 2012

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.

scientific article published on 11 May 2010

PUMA- and Bax-induced autophagy contributes to apoptosis

scientific article published on 20 March 2009

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

scientific article

Pinning a change on p53

scientific article published in Nature

Regulation and function of the p53 tumor suppressor protein

scientific article

Retrograde signaling from autophagy modulates stress responses.

scientific article published on 28 February 2017

Role of NF-κB in p53-mediated programmed cell death

scientific article published in Nature

Role of autophagy in cancer prevention, development and therapy

scientific article published on January 2013

Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.

scientific article published on 10 January 2013

Splicing DNA-damage responses to tumour cell death.

scientific article

TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival

scientific journal article

Targeting the p53 family for cancer therapy: 'big brother' joins the fight.

scientific article published on 19 June 2007

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

scientific article

The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy

scientific article published in November 2011

The multiple roles of autophagy in cancer

scientific article published on 11 February 2011

The role of autophagy in tumour development and cancer therapy.

scientific article published on 02 December 2009

Transcriptional regulation of autophagy and lysosomal function by bromodomain protein BRD4.

scientific article

Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy

scientific article

Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system

scientific article

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

scientific article

Using enhanced-mitophagy to measure autophagic flux.

scientific article

c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells

scientific article

iASPP inhibition: increased options in targeting the p53 family for cancer therapy.

scientific article published on July 2008

p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner

scientific article

p53 and autophagy in cancer: Guardian of the genome meets guardian of the proteome ⬇️

scientific article published on November 25, 2010

p53 and metabolism

scientific article (publication date: October 2009)

p53 and senescence: A little goes a long way

article

p53 and senescence: a little goes a long way.

scientific article published on October 2010

p53 and tumor surveillance: Killer finds way to recruit assassins

scientific article published on 15 November 2011

p53 status determines the role of autophagy in pancreatic tumour development

scientific article published on 4 December 2013

p53-mediated induction of Noxa and p53AIP1 requires NFkappaB.

scientific article

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival

scientific article published on 16 November 2010

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

scientific article published on 09 February 2015

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

scientific article published on 16 February 2007

Paulina is supported by:

About Paulina

Help