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List of works by Vassilios Papadopoulos

2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line

scientific article published on 19 May 2015

22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells

scientific article published on 3 August 2007

22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide

scientific article published on December 2002

3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA

scientific article published on 16 October 2006

A Lead Study on Oxidative Stress-Mediated Dehydroepiandrosterone Formation in Serum: The Biochemical Basis for a Diagnosis of Alzheimer's Disease

scientific article published on January 1, 2011

A capillary gas chromatography/mass spectrometric method for the quantification of hydroxysteroids in human plasma

scientific article

A novel Arabidopsis thaliana protein is a functional peripheral-type benzodiazepine receptor

scientific article

A novel conjugable translocator protein ligand labeled with a fluorescence dye for in vitro imaging

scientific article published on 7 June 2007

A novel functional translocator protein ligand for cancer imaging

scientific article published on 3 November 2007

A p38 mitogen-activated protein kinase inhibitor protects against renal damage in a non-heart-beating donor model

scientific article published on 30 April 2008

A steroid isolated from the water mold Achlya heterosexualis induces neurogenesis in vitro and in vivo

scientific article published on 26 November 2011

ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis

scientific article published on 11 May 2016

ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cells

scientific article

Abnormal morphology of spermatozoa in cytochrome P450 17alpha-hydroxylase/17, 20-lyase (CYP17) deficient mice

scientific article published on 24 January 2007

Acute action of choriogonadotropin on Leydig tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor

scientific article published on 01 December 1996

Acute action of choriogonadotropin on Leydig tumor cells: induction of a higher affinity benzodiazepine-binding site related to steroid biosynthesis

scientific article published on October 1994

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule.

scientific article

Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies

scientific article

Aging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells

scientific article

Alzheimer's disease: Effects of β-amyloid on mitochondria

scientific article published on September 15, 2010

Amhr2-Cre-Mediated Global Tspo Knockout

scientific article published on 12 January 2020

Axonal regeneration and neuroinflammation: roles for the translocator protein 18 kDa.

scientific article published on January 2012

Bacterial ortholog of mammalian translocator protein (TSPO) with virulence regulating activity.

scientific article

Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain

scientific article

Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols

scientific article (publication date: September 2014)

Calcium-calmodulin-dependent phosphorylation of cytoskeletal proteins from adrenal cells

scientific article published in December 1990

Caprospinol reduces amyloid deposits and improves cognitive function in a rat model of Alzheimer's disease

scientific article published in January 2010

Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties

scientific article published on January 2012

Caprospinol: moving from a neuroactive steroid to a neurotropic drug

scientific article published on 01 March 2009

Carbenoxolone induces permeability transition pore opening in rat mitochondria via the translocator protein TSPO and connexin43.

scientific article

Celebrating the Silver Anniversary of the North American Testis Workshop

scientific article published on 22 January 2020

Cell surface localization of the peripheral-type benzodiazepine receptor (PBR) in adrenal cortex

scientific article published in September 1992

Changes in androgen binding protein (ABP) production following continuous low dose gamma irradiation (IR) of adult rat

scientific article published on 01 October 1988

Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response

scientific article (publication date: 2007)

Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor

scientific article published on 4 November 2004

Characterization of the mouse promoter region of the acyl-CoA synthetase 4 gene: role of Sp1 and CREB.

scientific article published on 31 January 2013

Cholesterol accumulation, lipid droplet formation, and steroid production in Leydig cells: Role of translocator protein (18-kDa)

scientific article published on 18 November 2019

Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

scientific article

Cholesterol homeostasis and infertility: the liver X receptor connection.

scientific article

Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.

scientific article published on 12 March 2009

Cloning, sequencing, and chromosomal localization of pig peripheral benzodiazepine receptor: three different forms produced by alternative splicing

scientific article published on 3 October 2006

Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria

scientific article published on 20 October 2015

Computational modeling and biological validation of novel non-steroidal ligands for the cholesterol recognition/interaction amino acid consensus (CRAC) motif of the mitochondrial translocator protein (TSPO).

scientific article published on 29 April 2015

Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.

scientific article published on 26 May 2015

Control of hypercholesterolemia and atherosclerosis using the cholesterol recognition/interaction amino acid sequence of the translocator protein TSPO.

scientific article published on 23 November 2012

Cutting-edge patents in Alzheimer's disease drug discovery: anticipation of potential future treatments

scientific article

Cyclohexane-1,2-dicarboxylic acid diisononyl ester and metabolite effects on rat epididymal stromal vascular fraction differentiation of adipose tissue

scientific article published on 9 April 2015

Cyclohexane-1,2-dicarboxylic acid diisononyl ester and metabolite effects on rat epididymal stromal vascular fraction differentiation of adipose tissue (2015) Environmental Research 140: 145-156 Reply to the letter by Otter R

scientific article published on 17 November 2015

Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells

scientific article

De novo steroid biosynthesis in human prostate cell lines and biopsies

scientific article published on 4 February 2016

Deficiency in the α1 subunit of Na+/K+-ATPase enhances the anti-proliferative effect of high osmolality in nucleus pulposus intervertebral disc cells.

scientific article published on 12 May 2015

Dehydroepiandrosterone formation is independent of cytochrome P450 17alpha-hydroxylase/17, 20 lyase activity in the mouse brain.

scientific article published on 27 March 2009

Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells

scientific article published on March 17, 1998

Developmental expression of the peripheral-type benzodiazepine receptor and the advent of steroidogenesis in rat adrenal glands

scientific journal article

Diazepam effects on carrageenan-induced inflammatory paw edema in rats: role of nitric oxide

scientific article published on 24 January 2006

Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity

scientific journal article

Directing differentiation of human induced pluripotent stem cells toward androgen-producing Leydig cells rather than adrenal cells

scientific article published on 07 October 2019

Disrupting mitochondrial function with surfactants inhibits MA-10 Leydig cell steroidogenesis

scientific article published on 11 April 2007

Drug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged brown Norway rat Leydig cells

scientific article published on 22 March 2013

Dual compartment (bicameral) culture: role of basement membrane in epithelial differentiation

scientific article published on July 1992

Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells

scientific article published in March 2001

Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha

scientific article

Effect of phorbol ester and phospholipase C on LH-stimulated steroidogenesis in purified rat Leydig cells

scientific article published on 01 September 1985

Effect of prenatal DINCH plasticizer exposure on rat offspring testicular function and metabolism

scientific article

Effect of translocator protein (18 kDa)-ligand binding on neurotransmitter-induced salivary secretion in rat submandibular glands

scientific article published in July 2008

Effects of cisplatin and bleomycin on mature rat Leydig cell testosterone production

scientific article published on January 1988

Effects of seminiferous tubule secreted factor(s) on Leydig cell cyclic AMP production in mature rat.

scientific article

Effects of the transmethylation inhibitor S-adenosyl-homocysteine and of the methyl donor S-adenosyl-methionine on rat Leydig cell function in vitro

scientific article published on 01 January 1987

Endozepine/diazepam binding inhibitor in adrenocortical and Leydig cell lines: absence of hormonal regulation

scientific article published on January 1992

Erratum to "Cyclohexane-1,2-dicarboxylic acid diisononyl ester and metabolite effects on rat epididymal stromal vascular fraction differentiation of adipose tissue" [Environ. Res. 140 (2015) 145-156]

scientific article published on 12 November 2015

Evidence for a mitochondrial impact of trimetazidine during cold ischemia and reperfusion

scientific article published in May 2004

Evidence for a protective role of trimetazidine during cold ischemia: targeting inflammation and nephron mass

scientific article published in December 2003

Evidence for sigma-1-like receptors in isolated rat liver mitochondrial membranes

scientific article published on April 2002

Evolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animals

scientific article

Expression of peripheral benzodiazepine receptor (PBR) in human tumors: relationship to breast, colorectal, and prostate tumor progression

scientific article published in January 2003

Expression of steroidogenesis-related genes in murine male germ cells

scientific article published on 21 August 2015

Fetal origin of endocrine dysfunction in the adult: the phthalate model

scientific article published on 17 January 2013

Free radicals and lipid peroxidation do not mediate beta-amyloid-induced neuronal cell death

scientific article published on 01 November 1999

From benzodiazepines to peripheral and brain steroid biosynthesis

scientific article published on 17 June 2011

Functional characterization of the human translocator protein (18kDa) gene promoter in human breast cancer cell lines.

scientific article published on 18 September 2011

Further evidence on mitochondrial targeting of β-amyloid and specificity of β-amyloid-induced mitotoxicity in neurons

scientific article published on 11 February 2011

Gestational exposure to atrazine: effects on the postnatal development of male offspring

scientific article published on 31 October 2007

Ginkgo biloba extract (Egb 761) inhibits beta-amyloid production by lowering free cholesterol levels.

scientific article

Ginkgo biloba extracts and cancer: a research area in its infancy.

scientific article

GnRH agonist treatment decreases progesterone synthesis, luteal peripheral benzodiazepine receptor mRNA, ligand binding and steroidogenic acute regulatory protein expression during pregnancy

scientific article published on 01 February 1999

Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice.

scientific article published on 12 May 2005

Hormone-dependent expression of a steroidogenic acute regulatory protein natural antisense transcript in MA-10 mouse tumor Leydig cells

scientific article

Hormone-induced 14-3-3γ Adaptor Protein Regulates Steroidogenic Acute Regulatory Protein Activity and Steroid Biosynthesis in MA-10 Leydig Cells

scientific article published on March 16, 2012

How does an undergraduate pain course influence future physicians' awareness of chronic pain concepts? A comparative study

scientific article published on 15 September 2014

Identification and partial characterization of laminin binding proteins in immature rat Sertoli cells

scientific article published on 01 April 1991

Identification of Sec23ip, Part of 14-3-3γ Protein Network, as a Regulator of Acute Steroidogenesis in MA-10 Leydig Cells

scientific article published on 01 February 2020

Identification of a benzamide derivative that inhibits stress-induced adrenal corticosteroid synthesis.

scientific article published on 3 September 2009

Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones

scientific article

Identification of a peptide antagonist to the peripheral-type benzodiazepine receptor that inhibits hormone-stimulated leydig cell steroid formation

scientific article published in November 2002

Identification of hot spots of DNA methylation in the adult male adrenal in response to in utero exposure to the ubiquitous endocrine disruptor plasticizer di-(2-ethylhexyl) phthalate

scientific article published in January 2015

Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity

scientific article

Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design.

scientific article

Identification of the adrenocorticotropin and ginkgolide B-regulated 90-kilodalton protein (p90) in adrenocortical cells as a serotransferrin precursor protein homolog (adrenotransferrin).

scientific article published on 30 December 2003

Identification of transferrin and inhibin-like proteins in matrigel

scientific article published on 01 June 1995

Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against beta-amyloid-induced toxicity

scientific article published on April 2005

In search of rat stem Leydig cells: identification, isolation, and lineage-specific development.

scientific article

In search of the function of the peripheral-type benzodiazepine receptor.

scientific article

In search of the molecular mechanisms mediating the inhibitory effect of the GnRH antagonist degarelix on human prostate cell growth

scientific article

In silico analysis identifies novel restriction enzyme combinations that expand reduced representation bisulfite sequencing CpG coverage.

scientific article

In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis.

scientific article published on 09 October 2009

In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat.

scientific article

In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat.

scientific article

In utero exposure to the endocrine disruptor di(2-ethylhexyl) phthalate targets ovarian theca cells and steroidogenesis in the adult female rat.

scientific article published on 18 December 2014

In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate induces long-term changes in gene expression in the adult male adrenal gland

scientific article published on 24 February 2014

In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate promotes local adipose and systemic inflammation in adult male offspring.

scientific article

In vitro action of PG F2 alpha on progesterone and cAMP synthesis in small bovine luteal cells

scientific article published on 01 February 1987

In vitro functional screening as a means to identify new plasticizers devoid of reproductive toxicity.

scientific article published on 14 July 2016

In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding.

scientific article published in April 2003

In vivo regulation of peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract EGb 761 and isolated ginkgolides

scientific article published on December 1996

Induction of androgen formation in the male by a TAT-VDAC1 fusion peptide blocking 14-3-3ɛ protein adaptor and mitochondrial VDAC1 interactions

scientific article published on 20 June 2014

Influence of warm ischemia time on peripheral-type benzodiazepine receptor: a new aspect of the role of mitochondria

scientific article published on 05 July 2007

Inhibition of adrenal cortical steroid formation by procaine is mediated by reduction of the cAMP-induced 3-hydroxy-3-methylglutaryl-coenzyme A reductase messenger ribonucleic acid levels

scientific article published on 14 October 2003

Insight into the Structural Features of TSPO: Implications for Drug Development

scientific article published on 18 December 2019

Is there a mitochondrial signaling complex facilitating cholesterol import?

scientific article published on 5 February 2007

Isolation and characterisation of calcineurin from adrenal cell cytoskeleton: identification of substrates for Ca2+-calmodulin-dependent phosphatase activity

scientific article published on 01 May 1989

Leydig cell aging and hypogonadism

scientific article

Lifelong cell-cell interactions in the testis: a driver for male fertility. Summary of the XXVth North American Testis Workshop

scientific article published on 02 June 2020

Local anesthetic procaine protects rat pheochromocytoma PC12 cells against beta-amyloid-induced neurotoxicity

scientific article

Maternal in utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate affects the blood pressure of adult male offspring

scientific article published on 08 November 2012

Mechanisms mediating environmental chemical-induced endocrine disruption in the adrenal gland

scientific article

Methodology for multi-site ligand-protein docking identification developed for the optimization of spirostenol inhibition of beta-amyloid-induced neurotoxicity

scientific article

Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3.

scientific article

Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells

scientific article published on 29 December 2020

Mitochondrial peripheral-type benzodiazepine receptor expression. Correlation with gonadotropin-releasing hormone (GnRH) agonist-induced apoptosis in the corpus luteum

scientific article published on 01 November 1999

Mitochondrial protein import and the genesis of steroidogenic mitochondria

scientific article published on December 13, 2010

Modeling Alzheimer's disease with non-transgenic rat models

scientific article published on May 2013

Modulation of peripheral-type benzodiazepine receptor during ischemia reperfusion injury in a pig kidney model: a new partner of leukemia inhibitory factor in tubular regeneration

scientific article published on 13 July 2006

Modulation of peripheral-type benzodiazepine receptor levels in a reperfusion injury pig kidney-graft model

scientific article published on 01 December 2002

Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RIalpha associated protein

scientific article published in April 2003

Molecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cells

scientific article

NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1.

scientific article published on August 2006

Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity

scientific article published on January 2006

Neurotrophic estrogens: essential profile and endpoints for drug discovery.

scientific article published on 15 May 2008

Novel Androstenetriol Interacts with the Mitochondrial Translocator Protein and Controls Steroidogenesis

scientific article published on January 5, 2011

On the role of the translocator protein (18-kDa) TSPO in steroid hormone biosynthesis

scientific article published on 01 January 2014

Organelle plasticity and interactions in cholesterol transport and steroid biosynthesis.

scientific article published on 13 December 2012

Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer's Disease Diagnosis

scientific article

Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cells

scientific article published on 19 August 2013

Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology

scientific article

PBR, StAR, and PKA: partners in cholesterol transport in steroidogenic cells.

scientific article

Pachytene spermatocytes regulate the secretion of Sertoli cell protein(s) which stimulate Leydig cell steroidogenesis

scientific article published on May 1991

Pathways of dehydroepiandrosterone formation in rat brain glia

scientific article published in December 2000

Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and beta-amyloid peptide

scientific article published on 01 February 2000

Peripheral-type benzodiazepine receptor (PBR) and PBR drug ligands in fibroblast and fibrosarcoma cell proliferation: role of ERK, c-Jun and ligand-activated PBR-independent pathways

scientific article

Peripheral-type benzodiazepine receptor (PBR) gene amplification in MDA-MB-231 aggressive breast cancer cells

scientific article published on November 2002

Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.

scientific article

Peripheral-type benzodiazepine receptor levels correlate with the ability of human breast cancer MDA-MB-231 cell line to grow in SCID mice

scientific article

Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation

scientific article published on 29 October 2006

Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria

scientific article

Pharmacological regulation of the cholesterol transport machinery in steroidogenic cells of the testis

scientific article published on 14 February 2015

Phorbol-12-myristate 13-acetate acting through protein kinase Cepsilon induces translocator protein (18-kDa) TSPO gene expression

scientific article published on December 2008

Polyethylene glycol reduces early and long-term cold ischemia-reperfusion and renal medulla injury

scientific article published in September 2002

Prenatal exposure of rats to Ginkgo biloba extract (EGb 761) increases neuronal survival/growth and alters gene expression in the developing fetal hippocampus

scientific article

Prenatal phthalate exposure: epigenetic changes leading to lifelong impact on steroid formation

scientific article published on 4 April 2016

Protein modifications regulate the role of 14-3-3γ adaptor protein in cAMP-induced steroidogenesis in MA-10 Leydig cells.

scientific article

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

scientific article published on 18 October 2006

Protoporphyrin IX binding and transport by recombinant mouse PBR.

scientific article published in November 2003

Purification and characterization of equine testicular cytochrome P-450 aromatase: comparison with the human enzyme

scientific article published on 01 September 1997

Rat Sertoli cell aromatase cytochrome P450: regulation by cell culture conditions and relationship to the state of cell differentiation

scientific article published on 01 December 1993

Rat testis 17 beta-estradiol: identification by gas chromatography-mass spectrometry and age related cellular distribution

scientific article

Redox regulation of hormone sensitive lipase: Potential role in the mechanism of MEHP-induced stimulation of basal steroid synthesis in MA-10 Leydig cells

scientific article published on 14 January 2019

Regulation of rat testis gonocyte proliferation by platelet-derived growth factor and estradiol: identification of signaling mechanisms involved

scientific article published on March 1997

Repeated exposures of the male Sprague Dawley rat reproductive tract to environmental toxicants: Do earlier exposures to di-(2-ethylhexyl)phthalate (DEHP) alter the effects of later exposures?

scientific article published on 31 March 2016

Reversible changes in adrenocorticotropin (ACTH)-induced adrenocortical steroidogenesis and expression of the peripheral-type benzodiazepine receptor during the ACTH-insensitive period in young rats

scientific article published on 12 February 2004

Role of mitochondria in steroidogenesis

scientific article published on 16 June 2012

Role of the peripheral-type benzodiazepine receptor and the polypeptide diazepam binding inhibitor in steroidogenesis

scientific article

Role of translocator protein in melanoma growth and progression.

scientific article published on 19 October 2012

Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

scientific article published on 27 March 2008

Stem Leydig cell differentiation: gene expression during development of the adult rat population of Leydig cells

scientific article published on 10 August 2011

Steroid biosynthesis in adipose tissue

scientific article published on 03 April 2015

Steroid production in the thymus: implications for thymocyte selection.

scientific article

Steroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria

scientific article published on 10 September 2014

Steroidogenesis: The Classics and Beyond

scientific article published on 01 November 2015

Steroidogenic fate of the Leydig cells that repopulate the testes of young and aged Brown Norway rats after elimination of the preexisting Leydig cells

scientific article

Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells

scientific article

Stimulatory effects of combined endocrine disruptors on MA-10 Leydig cell steroid production and lipid homeostasis.

scientific article published on 12 May 2016

Structural Studies of TSPO, a Mitochondrial Membrane Protein

Structural and functional study of reconstituted peripheral benzodiazepine receptor

scientific article published in June 2001

Structure-activity relationship (SAR) analysis of a family of steroids acutely controlling steroidogenesis

scientific article

Studies on the phosphorylation of the 18 kDa mitochondrial benzodiazepine receptor protein

scientific article published on May 1994

Subcellular injuries in Alzheimer's disease

scientific article published on January 2014

Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor

scientific article published on 01 August 1997

Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line

scientific journal article

Targeting and insertion of the cholesterol-binding translocator protein into the outer mitochondrial membrane.

scientific article published on July 2009

The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from beta-amyloid-induced cell death by inhibiting the formation of beta-amyloid-derived diffusible neurotoxic ligands.

scientific article

The GnRH Antagonist Degarelix Directly Inhibits Benign Prostate Hyperplasia Cell Growth.

scientific article published on 21 July 2015

The endocrine disruptor mono-(2-ethylhexyl) phthalate affects the differentiation of human liposarcoma cells (SW 872)

scientific article

The naturally occurring steroid solasodine induces neurogenesis in vitro and in vivo.

scientific article published on 7 April 2011

The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria

scientific journal article

The peroxisome proliferator perfluorodecanoic acid inhibits the peripheral-type benzodiazepine receptor (PBR) expression and hormone-stimulated mitochondrial cholesterol transport and steroid formation in Leydig cells

scientific article published on 01 September 2000

The role of Ets transcription factors in the basal transcription of the translocator protein (18 kDa).

scientific article published on 3 April 2007

The role of the 14-3-3 protein family in health, disease, and drug development

scientific article published on 06 October 2015

The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function

scientific article published on 19 June 2006

Transcriptional suppression of the adrenal cortical peripheral-type benzodiazepine receptor gene and inhibition of steroid synthesis by ginkgolide B.

scientific article published on March 2003

Translocator Protein-Mediated Stabilization of Mitochondrial Architecture during Inflammation Stress in Colonic Cells

scientific article

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

scientific article published on December 2010

Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma

scientific article

Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis

scientific article published on 26 June 2015

Translocator protein (18 kDa) as a target for novel anxiolytics with a favourable side-effect profile

scientific article published on January 2012

Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells

scientific article

Translocator protein (18 kDa) mediates the pro-growth effects of diazepam on Ehrlich tumor cells in vivo

scientific article published on 24 September 2009

Translocator protein (18 kDa): an update on its function in steroidogenesis

scientific article

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

scientific article

Translocator protein (Tspo) gene promoter-driven green fluorescent protein synthesis in transgenic mice: an in vivo model to study Tspo transcription

scientific article published on 07 August 2012

Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis

scientific article

Translocator protein: pharmacology and steroidogenesis

scientific article published on 03 August 2015

Ultrastructural distribution of calcium in the rat testis

scientific article published on 01 July 1994

Why does COVID-19 kill more elderly men than women? Is there a role for testosterone?

scientific article published on 18 July 2020

gamma-Aminobutyric acid type A/benzodiazepine receptors regulate rat retina neurosteroidogenesis

scientific article published on June 1995