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List of works by Jens Staal

A Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation

scientific article published on 31 October 2018

A Two-Step Activation Mechanism of MALT1 Paracaspase ⬇️

scientific article published on March 15, 2012

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

scientific article published on 21 October 2019

A novel role of PR2 in abscisic acid (ABA) mediated, pathogen-induced callose deposition in Arabidopsis thaliana

scientific article published on 19 August 2013

ABA is required for Leptosphaeria maculans resistance via ABI1- and ABI4-dependent signaling

scientific article published on 01 April 2007

Abscisic Acid as Pathogen Effector and Immune Regulator

scientific article published on 19 April 2017

Ancient Origin of the CARD-Coiled Coil/Bcl10/MALT1-Like Paracaspase Signaling Complex Indicates Unknown Critical Functions.

scientific article

Author Correction: A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

scientific article published on 20 November 2019

Characterisation of an Arabidopsis-Leptosphaeria maculans pathosystem: resistance partially requires camalexin biosynthesis and is independent of salicylic acid, ethylene and jasmonic acid signalling

scientific article published in January 2004

Cleavage by MALT1 induces cytosolic release of A20.

scientific article published on 20 September 2010

Defining the combinatorial space of PKC::CARD-CC signal transduction nodes

scientific article published on 13 August 2020

Deletion of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis

scientific article published on 09 November 2019

Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome

scientific article published on 01 June 2020

Early responses in the Arabidopsis-Verticillium longisporum pathosystem are dependent on NDR1, JA- and ET-associated signals via cytosolic NPR1 and RFO1

scientific article published on 01 September 2006

Engineering a minimal cloning vector from a pUC18 plasmid backbone with an extended multiple cloning site

scientific article published on 24 May 2019

GC Content of Early Metazoan Genes and Its Impact on Gene Expression Levels in Mammalian Cell Lines.

scientific article

Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 as a Case Study

scientific article

Inflammation and NF-κB Signaling in Prostate Cancer: Mechanisms and Clinical Implications

scholarly article by Jens Staal & Rudi Beyaert published 29 August 2018 in Cells

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice

scholarly article by E Kip et al published 29 August 2018 in Journal of Virology

Layers of defense responses to Leptosphaeria maculans below the RLM1- and camalexin-dependent resistances

scientific article published on 11 February 2009

Long-Term MALT1 Inhibition in Adult Mice Without Severe Systemic Autoimmunity

scientific article published on 12 September 2020

MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner

scientific article published on 14 August 2019

MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-κB signaling

scientific article

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

scientific article published on 24 January 2018

MALT1 is not alone after all: identification of novel paracaspases

scientific article

MALT1 targeting suppresses CARD14-induced psoriatic dermatitis in mice

scientific article published on 28 April 2020

MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging

scientific article published on 01 October 2019

Mepazine Inhibits RANK-Induced Osteoclastogenesis Independent of Its MALT1 Inhibitory Function

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.

scientific article published on 22 August 2016

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis.

scientific article

Prolonged exposure to IL-1beta and IFNgamma induces necrosis of L929 tumor cells via a p38MAPK/NF-kappaB/NO-dependent mechanism

scientific article published on 4 February 2008

RLM3, a TIR domain encoding gene involved in broad-range immunity of Arabidopsis to necrotrophic fungal pathogens

scientific article published on 4 April 2008

RLM3, a potential adaptor between specific TIR-NB-LRR receptors and DZC proteins

scientific article

Regulation of NF-κB signaling by caspases and MALT1 paracaspase

scientific article

Sensing of viral infection and activation of innate immunity by toll-like receptor 3

scientific article

Stabilization of the TAK1 adaptor proteins TAB2 and TAB3 is critical for optimal NF-κB activation

scientific article published on 29 January 2020

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

scientific article

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

scientific article

Targeting MALT1 Proteolytic Activity in Immunity, Inflammation and Disease: Good or Bad?

scientific article

The CARD-CC/Bcl10/paracaspase signaling complex is functionally conserved since the last common ancestor of planulozoa

The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination

scientific article published on July 2015

The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes

scientific journal article

Tracing the ancient origins of plant innate immunity.

scientific article published on 20 July 2007

Transgressive segregation reveals two Arabidopsis TIR-NB-LRR resistance genes effective against Leptosphaeria maculans, causal agent of blackleg disease

scientific article published in April 2006

Ubiquitination and phosphorylation of the CARD11-BCL10-MALT1 signalosome in T cells

scientific article published on 01 December 2018

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