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List of works by Floris Foijer

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

scientific article

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

scientific article published on 13 February 2020

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects: Berkeley, CA, USA. 26 - 29 January 2017.

scientific article

Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition

scientific article published on 24 January 2020

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

scientific article published on 28 June 2011

Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2.

scientific article published on 20 October 2008

Aneuploidy in stem cells

scientific article

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

scientific article published on 27 January 2021

Better check late than never: The chromosome segregation checkpoint (comment on DOI 10.1002/bies.201400140)

scientific article published on 16 January 2015

BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome

scientific article published on 01 January 2020

CIN and Aneuploidy: Different Concepts, Different Consequences.

scientific article published on 21 November 2017

CINcere Modelling: What Have Mouse Models for Chromosome Instability Taught Us?

scientific article published on January 2015

CINister thoughts ⬇️

scientific article published on December 1, 2010

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals

scientific article

Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway

scientific article published on 23 November 2020

Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.

scientific article

Check, double check: the G2 barrier to cancer.

scientific article

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

scientific article published in 2022

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

scientific article

Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small cell lung cancer patient.

scientific article

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

scientific article

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

scientific article published on 23 January 2020

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

scientific article published on 30 June 2016

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence

scientific article published in Nature Communications

Genetic instability from a single S phase after whole-genome duplication

scientific article published on 30 March 2022

How to count chromosomes in a cell: An overview of current and novel technologies

scientific article

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

scientific article published in March 2018

In vivo significance of the G2 restriction point

scientific article published in October 2007

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

scientific article published on 15 June 2010

Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells

scientific article published on 16 October 2018

Mitogen requirement for cell cycle progression in the absence of pocket protein activity

scientific article published on 01 December 2005

Non-random Mis-segregation of Human Chromosomes.

scientific article published in June 2018

Oncogenic pathways impinging on the G2-restriction point

scientific article published on 13 August 2007

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

scientific article published on 29 April 2019

PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

scientific article published on 23 November 2020

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

scientific article

Quantification of Aneuploidy in Mammalian Systems

scientific article published on 01 January 2019

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation.

scientific article

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

scientific article published on 16 October 2021

Restriction beyond the restriction point: mitogen requirement for G2 passage

scientific article

Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).

scientific article published on 14 June 2017

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

scientific article (publication date: 2016)

Single-cell sequencing to quantify genomic integrity in cancer

scientific article published on 23 September 2017

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

scientific article published on 31 May 2016

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

scientific article published on 4 February 2013

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

scientific article published on 30 November 2021

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

scientific article published on 03 September 2018

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

scientific article published on 09 November 2021

The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability

scientific article published on 10 October 2019

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

scientific article published on 01 October 2018

Transient genomic instability drives tumorigenesis through accelerated clonal evolution

scientific article published on 15 July 2021

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies

scientific article published in June 2017

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