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List of works by Catherine M. Hawrylowicz

1α,25-dihydroxyvitamin D3 acts via transforming growth factor-β to up-regulate expression of immunosuppressive CD73 on human CD4+ Foxp3- T cells

scientific article

1α,25-dihydroxyvitamin D3 in combination with transforming growth factor-β increases the frequency of Foxp3⁺ regulatory T cells through preferential expansion and usage of interleukin-2

scientific article

1α,25-dihydroxyvitamin D3 promotes CD200 expression by human peripheral and airway-resident T cells

scientific article

A comparative phase 1 clinical trial to identify anti-infective mechanisms of vitamin D in people with HIV infection

scientific article published in June 2015

A defect in corticosteroid-induced IL-10 production in T lymphocytes from corticosteroid-resistant asthmatic patients.

scientific article

A direct role for vitamin D-binding protein in the pathogenesis of COPD? ⬇️

scientific article published on January 13, 2011

A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection

scientific article

A novel technique to explore the functions of bronchial mucosal T cells in chronic obstructive pulmonary disease: application to cytotoxicity and cytokine immunoreactivity ⬇️

scientific article published in September 2010

A randomized placebo‐controlled trial of rush preseasonal depigmented polymerized grass pollen immunotherapy* ⬇️

article by O. Pfaar et al published 23 November 2011 in Allergy

ASTHMA - comparing the impact of vitamin D versus UVR on clinical and immune parameters.

scientific article published on 16 January 2017

Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses

scientific article published on 20 March 2017

Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators

scientific article

Asthma and allergy: The early beginnings

CXCR4 expression on monocytes is up-regulated by dexamethasone and is modulated by autologous CD3+ T cells

scientific article

Cell-cycle control in lymphocyte stimulation

scientific article published on 01 January 1984

Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes

scientific article

Counter regulation of the high affinity IgE receptor, FcepsilonRI, on human airway dendritic cells by IL-4 and IL-10.

scientific article published on 6 April 2009

Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma.

scientific article published on 17 December 2013

Dendritic cell phenotype in severe asthma reflects clinical responsiveness to glucocorticoids.

scientific article published on 11 November 2017

Depigmented-polymerised allergoids favour regulatory over effector T cells: enhancement by 1α, 25-dihydroxyvitamin D3.

scientific article

Depressed spontaneous natural killing and interferon augmentation in patients with malignant lymphoma

article

Developments in the field of allergy in 2013 through the eyes of Clinical and Experimental Allergy.

scientific article

Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-γ(high) immunophenotypes: Potential benefits of calcitriol

scientific article

Double-blind randomised placebo-controlled trial of bolus-dose vitamin D3 supplementation in adults with asthma (ViDiAs).

scientific article

Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial

scientific article published on January 2016

Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter

scientific article published in PLoS ONE

Effects of vitamin D supplementation on circulating concentrations of growth factors and immune-mediators in healthy women during pregnancy

scientific article published on 20 April 2020

Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion

scientific article published on 15 May 2013

Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database.

scientific article published on 27 June 2018

Functional plasticity of human respiratory tract dendritic cells: GM-CSF enhances T(H)2 development

scientific article published on 3 October 2005

Glucocorticoids drive human CD8(+) T cell differentiation towards a phenotype with high IL-10 and reduced IL-4, IL-5 and IL-13 production

scientific article published on 01 August 2000

Glucocorticosteroids Are Potential Confounders in Studies of Vitamin D and Asthma ⬇️

scientific article published on June 1, 2012

High-Dose IL-2 Skews a Glucocorticoid-Driven IL-17IL-10 Memory CD4 T Cell Response towards a Single IL-10-Producing Phenotype

scientific article published on 31 December 2018

Human spleen cells mediating natural killing: Altered natural cytotoxicity of spleen effector cells from patients with carcinoma

scientific article published on 01 January 1983

Immunological intervention in human diseases

scientific article published on 23 November 2007

Immunoregulatory mechanisms of vitamin D relevant to respiratory health and asthma

scientific article published on 16 April 2014

Impaired secretion of interleukin-4 and interleukin-13 by allergen-specific T cells correlates with defective nuclear expression of NF-AT2 and jun B: relevance to immunotherapy

scientific article published on September 2003

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

scientific article

Inhibition of human T-cell responses to house dust mite allergens by a T-cell receptor peptide

article

Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei

scientific article published on 20 February 2017

Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and beta2-agonists.

scientific article

Interleukin-10-secreting regulatory T cells in allergy and asthma

scientific article published on September 2006

Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans

scientific article

Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.

scientific article published on 12 January 2009

List of Contributors

Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?

scientific article

Monocytes and macrophages - friend or foe?

P89 Novel mechanisms of immunomodulation by vitamin D and α-1-antitrypsin

scientific article published on 14 November 2013

Plasmacytoid Dendritic Cells from Human Lung Cancer Draining Lymph Nodes Induce Tc1 Responses

article

Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma.

scientific article

Regulation of major histocompatibility complex class II antigens on human alveolar macrophages by granulocyte-macrophage colony-stimulating factor in the presence of glucocorticoids

scientific article published on 01 September 1999

Regulatory T Cells and Other Tolerogenic Mechanisms in Allergy and Asthma

Regulatory T cell therapy as individualized medicine for asthma and allergy

scientific article published on December 2007

Regulatory T cells and IL-10 in allergic inflammation

scientific article

Regulatory T cells in asthma

scientific article

Regulatory T cells in bronchial asthma

scientific article published on 12 February 2009

Regulatory T cells in human disease and their potential for therapeutic manipulation

scientific article

Regulatory T cells, inflammation and the allergic response-The role of glucocorticoids and Vitamin D.

scientific article published on 19 March 2010

Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma

scientific article

Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment

scientific article

Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

scientific article

Role of cysteinyl leukotrienes in human allergen-specific Th2 responses induced by granulocyte macrophage-colony stimulating factor

scientific article

Serum 25-dihydroxyvitamin D levels correlate with CD4+Foxp3+ T-cell numbers in moderate/severe asthma

scientific article published on 30 May 2012

Strategies for use of IL-10 or its antagonists in human disease

scientific article published on June 2008

Synergism of glucocorticoids with granulocyte macrophage colony stimulating factor (GM-CSF) but not interferon gamma (IFN-γ) or interleukin-4 (IL-4) on induction of HLA class II expression on human monocytes

scientific article published on 01 July 1992

T cells producing the anti-inflammatory cytokine IL-10 regulate allergen-specific Th2 responses in human airways

article

T regulatory cells and the control of allergic disease.

scientific article

T-cell receptor peptides that inhibit the T-cell response to allergen induce transforming growth factor-β production

scientific article published on 01 February 1996

Targeting the dendritic cell: the key to immunotherapy in cancer?

scientific article published on 01 March 2005

The Impact of Vitamin D on Regulatory T Cells ⬇️

scientific article published on February 1, 2011

The effects of calcitriol treatment in glucocorticoid-resistant asthma

scientific article published on 29 April 2014

The glucocorticoid receptor beta isoform can mediate transcriptional repression by recruiting histone deacetylases

scientific article published on 29 October 2007

The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells

scientific article

Urban Particulate Matter-Activated Human Dendritic Cells Induce the Expansion of Potent Inflammatory Th1, Th2, and Th17 Effector Cells.

scientific article published on 21 July 2015

Urban particulate matter stimulation of human dendritic cells enhances priming of naive CD8 T lymphocytes

scientific article

Urban particulate matter suppresses priming of T helper type 1 cells by granulocyte/macrophage colony-stimulating factor-activated human dendritic cells

scientific article published on February 2014

Viewpoint: A Potential Role for Platelet Derived Cytokines in the Inflammatory Response

scientific article published on 01 January 1993

Vitamin D Counteracts an IL-23-Dependent IL-17A+IFN-γ+ Response Driven by Urban Particulate Matter

scientific article published on 2 May 2017

Vitamin D and asthma in children

scientific article published on September 2011

Vitamin D and asthma: time for intervention?

scientific article published in May 2009

Vitamin D and lung disease

Vitamin D binding protein and asthma severity in children

scientific article published on 28 March 2012

Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease

scientific article

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.

scientific article published on 12 November 2014

Vitamin D in Asthma: Mechanisms of Action and Considerations for Clinical Trials

scientific article published on 15 September 2017

Vitamin D influences asthmatic pathology through its action on diverse immunological pathways

scientific article published on December 2014

Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial

scientific article published on 16 May 2017

Vitamin D, the immune system and asthma

scientific article

Vitamin D3 in inflammatory airway disease and immunosuppression

Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial

scientific article

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