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List of works by Anne T. Nies

A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter

scientific article (publication date: 8 November 2002)

A phosphotyrosine switch regulates organic cation transporters ⬇️

scientific article published on 16 March 2016

Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process

scientific article published on 10 July 2018

Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1).

scientific article published on 18 December 2013

Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis.

scientific article published in November 2003

Clinically Relevant OATP2B1 Inhibitors in Marketed Drug Space

scientific article published on 02 January 2020

Comment on "Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin".

scientific article

Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

scientific article published in August 2003

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

scientific article

DNA methylation of the SLC16A3 promoter regulates expression of the human lactate transporter MCT4 in renal cancer with consequences for clinical outcome

scientific article published on 23 July 2013

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

scientific article

Differential expression of drug uptake and efflux transporters in Japanese patients with hepatocellular carcinoma

scientific article

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs

scientific article published on 12 August 2020

Export pumps for anionic conjugates encoded by MRP genes.

scientific article published on January 1999

Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma

scientific article published on 01 June 2005

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

scientific article published in October 2009

Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B.

scientific article published on November 1998

Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma

scientific article (publication date: November 2001)

Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant

scientific article

Genetic biomarkers in epilepsy

scientific article published on April 2014

Histamine transport and metabolism are deranged in salivary glands in Sjogren's syndrome

scientific article published on 24 May 2013

Human Pregnane X Receptor Genotype of the Donor but Not of the Recipient Is a Risk Factor for Delayed Graft Function After Renal Transplantation

article

Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system

scientific article

Identification and functional characterization of the natural variant MRP3-Arg1297His of human multidrug resistance protein 3 (MRP3/ABCC3).

scientific article

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature

scientific article published on July 2015

Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs

scientific article published on 01 May 2008

Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family.

scientific article

MCT4 surpasses the prognostic relevance of the ancillary protein CD147 in clear cell renal cell carcinoma

scientific article published on 10 September 2015

Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics

scientific article published on 17 September 2011

Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects

scientific article published on 29 December 2012

Multidrug and toxin extrusion proteins as transporters of antimicrobial drugs

scientific article published on 13 September 2012

OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues

scientific article published on 16 February 2017

Organic anion transporters and their implications in pharmacotherapy.

scientific article

Organic cation transporter pharmacogenomics and drug–drug interaction

article

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

scientific article published on January 2011

Prostanoid transport by multidrug resistance protein 4 (MRP4/ABCC4) localized in tissues of the human urogenital tract

scientific article

Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)

scientific article

Purification of the human apical conjugate export pump MRP2 reconstitution and functional characterization as substrate-stimulated ATPase

scientific article

Retigabine/Ezogabine, a KCNQ/K(V)7 channel opener: pharmacological and clinical data

scientific article

Role of ABC transporters in fluoropyrimidine-based chemotherapy response.

scientific article

Solute carrier transporter and drug-related nephrotoxicity: the impact of proximal tubule cell models for preclinical research

scientific article published on 08 January 2014

Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here?

scientific article

Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine

scientific article published on 10 May 2016

Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia

scientific article published on 23 October 2017

Targeting OCT3 attenuates doxorubicin-induced cardiac injury

scientific article published in 2021

Testing association of rare genetic variants with resistance to three common antiseizure medications

scientific article published on 06 March 2020

The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans

scientific article published on 18 August 2020

The apical conjugate efflux pump ABCC2 (MRP2).

scientific article published on 18 July 2006

The fruit fly Drosophila melanogaster as an innovative preclinical ADME model for solute carrier membrane transporters, with consequences for pharmacology and drug therapy

scientific article published on 08 June 2018

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

article

Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).

scientific article published on 19 December 2007

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