List of works - Daulat Bikram Khadka

3-Arylisoquinolines as novel topoisomerase I inhibitors

scientific article

Application of ring-closing metathesis for the synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones

scientific article published on 01 January 2011

Computer-aided discovery of aminopyridines as novel JAK2 inhibitors

scientific article published on 16 January 2015

Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling

scientific article published on 20 May 2011

Design and synthesis of novel androgen receptor antagonists via molecular modeling

scientific article published on 30 December 2015

Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors

scientific article published on 3 February 2011

Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors

scientific article

Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA.

scientific article published on 24 August 2010

Discovery of Isoquinolinoquinazolinones as a Novel Class of Potent PPARγ Antagonists with Anti-adipogenic Effects

scientific article published on 03 October 2016

Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition

scientific article

Pharmacological effects of berberine and its derivatives: a patent update

scientific article

SAR based design of nicotinamides as a novel class of androgen receptor antagonists for prostate cancer

scientific article published on 5 April 2013

Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections

scientific article published on 27 November 2015

Structure-based virtual screening and identification of a novel androgen receptor antagonist.

scientific article

Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases

scientific article published on 28 August 2015

Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study

scientific article

Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents

scientific article published on 3 July 2010

Topoisomerase inhibitors as anticancer agents: a patent update

scientific article published on 23 April 2013

Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors

scientific article

List of works by Daulat Bikram Khadka

3-Arylisoquinolines as novel topoisomerase I inhibitors

Application of ring-closing metathesis for the synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones

Computer-aided discovery of aminopyridines as novel JAK2 inhibitors

Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling

Design and synthesis of novel androgen receptor antagonists via molecular modeling

Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors

Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors

Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA.

Discovery of Isoquinolinoquinazolinones as a Novel Class of Potent PPARγ Antagonists with Anti-adipogenic Effects

Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition

Pharmacological effects of berberine and its derivatives: a patent update

SAR based design of nicotinamides as a novel class of androgen receptor antagonists for prostate cancer

Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections

Structure-based virtual screening and identification of a novel androgen receptor antagonist.

Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases

Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study

Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents

Topoisomerase inhibitors as anticancer agents: a patent update

Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors