Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Christian Hölscher

1-50 of 166 results

View this query on the Wikidata Query Service
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

scientific article
The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.

scientific article published in April 2011
Nitric oxide, the enigmatic neuronal messenger: its role in synaptic plasticity.

scientific article published on July 1997
Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence

scientific article
Stimulation on the positive phase of hippocampal theta rhythm induces long-term potentiation that can Be depotentiated by stimulation on the negative phase in area CA1 in vivo

scientific article published in August 1997
TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

scientific article published in December 2013
Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology

scientific article published on 8 January 2016
Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease.

scientific article
Stress impairs performance in spatial water maze learning tasks

scientific article published in April 1999
Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease

scientific article published on 30 June 2009
Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system

scientific article published in August 2009
Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

scientific article published on 07 March 2014
Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease

scientific article published on 24 December 2009
Potential Role of Glucagon-Like Peptide-1 (GLP-1) in Neuroprotection

scientific article published on October 1, 2012
The selective neuronal NO synthase inhibitor 7-nitro-indazole blocks both long-term potentiation and depotentiation of field EPSPs in rat hippocampal CA1 in vivo.

scientific article published in January 1996
GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

scientific article published on 21 December 2011
Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain

scientific article published on 10 January 2011
Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice

scientific article
Investigation of the human brain metabolome to identify potential markers for early diagnosis and therapeutic targets of Alzheimer's disease

scientific article published on 8 January 2013
Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice

scientific article
Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease

scientific article published on August 1, 2011
Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats

scientific article
7-Nitro indazole, a selective neuronal nitric oxide synthase inhibitor in vivo, impairs spatial learning in the rat.

scientific article published in January 1996
An inhibitor of nitric oxide synthesis prevents memory formation in the chick

scientific article published in October 1992
Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo.

scientific article
Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

scientific article published on October 2010
The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease

scientific article published on 13 February 2012
Possible Causes of Alzheimer's Disease: Amyloid Fragments, Free Radicals, and Calcium Homeostasis

scientific article published on 18 September 2002
Inhibiting synthesis of the putative retrograde messenger nitric oxide results in amnesia in a passive avoidance task in the chick

scientific article published in August 1993
Reward modulates neuronal activity in the hippocampus of the rat.

scientific article published in June 2003
GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid

scientific article published on 29 March 2008
Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress

scientific article published on 28 October 2013
Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease.

scientific article published on June 2010
Val8-glucagon-like peptide-1 protects against Aβ1-40-induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats

scientific article published on 19 August 2010
Perirhinal cortex neuronal activity related to long-term familiarity memory in the macaque

scientific article
The incretin hormones glucagonlike peptide 1 and glucose‐dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease

scientific article published on February 1, 2014
The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease.

scientific article
Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory

scientific journal article
Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

scientific article
Time, space and hippocampal functions.

scientific article published on January 2003
The Role of GLP-1 in Neuronal Activity and Neurodegeneration

scientific article published on January 1, 2010
New roles for insulin-like hormones in neuronal signalling and protection: new hopes for novel treatments of Alzheimer's disease?

scientific article published on 18 October 2008
Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet

scientific article published on 30 March 2010
Metabotropic glutamate receptor activation and blockade: their role in long-term potentiation, learning and neurotoxicity

scientific article published in January 1999
The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain.

scientific article published on 28 December 2012
Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model

scientific article
Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease

scientific article published on 8 August 2014
First clinical data of the neuroprotective effects of nasal insulin application in patients with Alzheimer's disease

scientific article published on February 1, 2014
Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

scientific article published on 2 July 2015
Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases

scientific article published on April 1, 2014

Paulina is supported by:

About Paulina

Help