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List of works by Hans Bräuner-Osborne

(R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

scientific article published on 31 July 2009

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.

scientific article published in April 2003

(S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors

scientific article published on October 1997

1,2,3-triazolyl amino acids as AMPA receptor ligands

scientific article published on 14 October 2010

2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

scientific article published in July 2002

3-Pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing

scientific article published on 01 November 1999

3-Substituted 2-phenyl-indoles: privileged structures for medicinal chemistry

article

3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors.

scientific article

4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes.

scientific article published on January 2005

A cAMP Biosensor-Based High-Throughput Screening Assay for Identification of Gs-Coupled GPCR Ligands and Phosphodiesterase Inhibitors.

scientific article

A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid

scientific article published on August 1996

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity

scientific article published on 25 June 2010

Activity of L-alpha-amino acids at the promiscuous goldfish odorant receptor 5.24.

scientific article published on 20 March 2006

Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

scientific article

Allosteric modulation of the calcium-sensing receptor

scientific article published on September 2007

Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors

scientific article published on June 1995

Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils

scientific article published on 14 July 2017

Azetidinic amino acids: stereocontrolled synthesis and pharmacological characterization as ligands for glutamate receptors and transporters.

scientific article published on 29 September 2005

Biased agonism of the calcium-sensing receptor

scientific journal article

Calcium-Sensing Receptor Internalization Is β-Arrestin-Dependent and Modulated by Allosteric Ligands

scientific article published on 09 August 2019

Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors

scientific article published on October 2003

Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors.

scientific article published on August 2004

Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling.

scientific article

Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3.

scientific article published on December 2005

Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

scientific article published on November 2011

Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2.

scientific article published on 14 May 2007

Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D

scientific article

Computer-aided discovery of aromatic l-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139.

scientific article published on 30 May 2014

Constitutive activation of muscarinic receptors by the G-protein Gq.

scientific article published on April 1995

Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor

scientific article

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

scientific article

Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs

scientific article published on 04 August 2020

Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor

scientific article published on 5 September 2013

Design, synthesis, and in vitro pharmacology of new radiolabeled gamma-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity gamma-hydroxybutyric acid binding sites

scientific article published on September 2010

Design, synthesis, and pharmacological characterization of novel, potent NMDA receptor antagonists

scientific article published in December 2004

Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO).

scientific article published in May 2003

Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist

scientific article published on 30 March 2017

Detailed in vitro pharmacological characterization of clinically tested negative allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

scientific article published on 01 May 2020

Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity

scientific article published on March 2003

Differential compartmentalization and distinct functions of GABAB receptor variants

scientific article

Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

scientific article published on 01 October 2019

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile.

scientific article

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

scientific article published on 12 July 2019

Enhanced voluntary wheel running in GPRC6A receptor knockout mice

scientific article published on 14 May 2013

Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid.

scientific article published in March 1998

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

scientific article published on January 2012

FLIPR assays of intracellular calcium in GPCR drug discovery.

scientific article

Functional characterisation of homomeric ionotropic glutamate receptors GluR1-GluR6 in a fluorescence-based high throughput screening assay

scientific article published in February 2006

Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA.

scientific article published on 2 August 2007

Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking

scientific article published on December 2014

Functional importance of the Ala(116)-Pro(136) region in the calcium-sensing receptor. Constitutive activity and inverse agonism in a family C G-protein-coupled receptor

scientific article published on September 2000

Functional partial agonism at cloned human muscarinic acetylcholine receptors

scientific article published in October 1996

G protein-coupled receptor signaling analysis using homogenous time-resolved Förster resonance energy transfer (HTRF®) technology

scientific article

GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

scientific article published on 19 January 2021

Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

scientific article published on 16 December 2016

Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

scientific article published in May 2002

High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells

scientific article published on May 1995

Homology modelling of the GABA transporter and analysis of tiagabine binding

scientific article published on July 2010

Human GIP(3-30)NH2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

scientific article published on 25 January 2018

Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors

scientific article

Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site

scientific article published on 6 June 2017

Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method.

scientific article published on 6 July 2017

Identification of a novel scaffold for a small molecule GPR139 receptor agonist

scientific article published on 07 March 2019

Identification of the first surrogate agonists for the G protein-coupled receptor GPR132

article

Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

scientific article

Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice

scientific article published on 15 April 2013

Interaction of CPCCOEt with a chimeric mGlu1b and calcium sensing receptor

scientific article

Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo

scientific article published on 11 December 2012

Interactions of muscarinic receptors with the heterotrimeric G proteins Gq and G12: transduction of proliferative signals.

scientific article published on February 1997

Introduction to special issue in honor of Professor Povl Krogsgaard-Larsen

scientific article published in October 2014

Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches

scientific article

Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer

scientific article published on 18 April 2017

Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist

scientific article published on 01 January 2000

Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors

scientific article published on 09 February 2017

Known regulators of nitric oxide synthase and arginase are agonists at the human G-protein-coupled receptor GPRC6A.

scientific article published on April 2006

L-Arginine improves multiple physiological parameters in mice exposed to diet-induced metabolic disturbances

scientific article published on 27 December 2011

Label-free dynamic mass redistribution analysis of endogenous adrenergic receptor signaling in primary preadipocytes and differentiated adipocytes

scientific article published on 01 April 2019

Metabolic and skeletal homeostasis are maintained in full locus GPRC6A knockout mice

scientific article published on 12 April 2019

Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor

scientific article

Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor

scientific article published on November 2009

Molecular pharmacology of 4-substituted glutamic acid analogues at ionotropic and metabotropic excitatory amino acid receptors

scientific article published in September 1997

Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors.

scientific article

Molecular pharmacology of human NMDA receptors

scientific article published on 17 December 2011

Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients.

scientific article published on June 2009

Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues

scientific article

N-Hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands

scientific article

N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization

scientific article published on 21 January 2015

New analogues of ACPD with selective activity for group II metabotropic glutamate receptors

scientific article published on 01 August 1997

No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions.

scientific article

Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology

scientific article published in January 2002

Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: design, synthesis, and pharmacological characterization

scientific article published on September 2010

Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: synthesis and pharmacology at glutamate receptors

scientific article

Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139.

scientific article published on 10 November 2016

Novel approaches leading towards peptide GPCR de-orphanisation

scientific article published on 03 February 2020

Novel cyclic gamma-hydroxybutyrate (GHB) analogs with high affinity and stereoselectivity of binding to GHB sites in rat brain.

scientific article

Novel high-affinity and selective biaromatic 4-substituted gamma-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies.

scientific article

Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites

scientific article published on 9 August 2010

Novel strategies in drug discovery of the calcium-sensing receptor based on biased signaling

scientific article published on September 2012

Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice

scientific article published on 19 August 2013

Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

scientific article published on 16 August 2012

Pharmacological characterization of homobaclofen on wild type and mutant GABA(B)1b receptors coexpressed with the GABA(B)2 receptor

scientific article published on April 2001

Pharmacological characterization of human excitatory amino acid transporters EAAT1, EAAT2 and EAAT3 in a fluorescence-based membrane potential assay

scientific article published in June 2004

Pharmacological characterization of ligands at recombinant NMDA receptor subtypes by electrophysiological recordings and intracellular calcium measurements

scientific article

Pharmacological identification of a guanidine-containing β-alanine analogue with low micromolar potency and selectivity for the betaine/GABA transporter 1 (BGT1).

scientific article

Pharmacology and physiological function of the orphan GPRC6A receptor

scientific article published on 14 February 2020

Pharmacology of (S)-homoquisqualic acid and (S)-2-amino-5-phosphonopentanoic acid [(S)-AP5] at cloned metabotropic glutamate receptors

scientific article published in January 1998

Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells

scientific journal article

Phenylacetic acids and the structurally related non-steroidal anti-inflammatory drug diclofenac bind to specific gamma-hydroxybutyric acid sites in rat brain.

scientific article published in April 2009

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

scientific article

Probing intermolecular protein-protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET).

scientific article published on October 2002

Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands

scientific article published on 15 August 2019

Promiscuous seven transmembrane receptors sensing L-α-amino acids

scientific article published on January 2014

Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists

scientific article

Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3.

scientific article published on January 2006

Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity

scientific article published on 11 February 2019

Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogue

scientific article published in February 2003

Real-time trafficking and signaling of the glucagon-like peptide-1 receptor

scientific article published on 22 November 2013

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA.

scientific article

Rigid nonproteinogenic cyclic amino acids as ligands for glutamate receptors: trans-tris(homoglutamic) acids

scientific article published in February 2005

Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor

scientific article published on 10 December 2016

Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors

scientific article published on 14 May 2015

Selective Allosteric Antagonists for the G Protein-Coupled Receptor GPRC6A Based on the 2-Phenylindole Privileged Structure Scaffold

scientific article published on 30 October 2015

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants

scientific article published on 11 September 2015

Selective agonists at group II metabotropic glutamate receptors: synthesis, stereochemistry, and molecular pharmacology of (S)- and (R)-2-amino-4-(4-hydroxy[1,2,5]thiadiazol-3-yl)butyric acid

scientific article

Selective antagonists at group I metabotropic glutamate receptors: synthesis and molecular pharmacology of 4-aryl-3-isoxazolol amino acids

scientific article published in February 2002

Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain

scientific article

Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

scientific article published on 25 March 2022

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice

scientific article

Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells

scientific article published on 31 August 2012

Structural insight to mutation effects uncover a common allosteric site in class C GPCRs

scientific article published on 22 December 2016

Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors

scientific article

Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein

scientific article published on 16 May 2017

Structure-Activity Relationship Studies of the Natural Product Gq/11 Protein Inhibitor YM-254890

scientific article published on 21 March 2019

Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1).

scientific article

Structure-activity relationships for negative allosteric mGluR5 modulators

scientific article

Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors

scientific article

Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359

scientific article published on 12 July 2018

Synthesis and Pharmacology of a New AMPA−Kainate Receptor Agonist with Potent Convulsant Activity

scientific article published on 01 September 1998

Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids

scientific article

Synthesis and enantiopharmacology of new AMPA-kainate receptor agonists.

scientific article

Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues

scientific article published on October 2003

Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline

scientific article

Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

scholarly article by Paola Conti et al published March 2007 in Tetrahedron

Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid

scientific article

Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists

scientific article published on 17 December 2014

Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid.

scientific article

Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors.

scientific article published in March 2001

Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid.

scientific article published in June 1998

Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid

scientific article published in February 2007

Synthesis and receptor binding affinity of new selective GluR5 ligands

scientific article published on April 2001

Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists.

scientific article

Synthesis of Conformationally Constrained Glutamic Acid Homologues and Investigation of Their Pharmacological Profiles

scientific article published on 01 November 2007

Synthesis of NovelN1-Substituted Bicyclic Pyrazole Amino Acids and Evaluation of Their Interaction with Glutamate Receptors

scientific article published on 01 June 2005

Synthesis of the calcilytic ligand NPS 2143

scientific article published on 9 July 2013

Synthesis, binding affinity at glutamic acid receptors, neuroprotective effects, and molecular modeling investigation of novel dihydroisoxazole amino acids

scientific article

Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.

scientific article published in August 2004

Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology.

scientific article

The GABAB1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses.

scientific article published in February 2009

The GPCR, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function

scientific article published on March 2014

The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site

scientific article

The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway

scientific article published on 9 March 2017

The L-α-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

scientific article published on 20 June 2012

The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain

scientific article published on June 1999

The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors.

scientific article published in June 2002

The dance of the clams: twists and turns in the family C GPCR homodimer

scientific article published on 01 November 2002

The emerging role of promiscuous 7TM receptors as chemosensors for food intake

scientific article published on January 2010

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

scientific article

The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.

scientific article published on December 2016

The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.

scientific article

The rat GPRC6A: cloning and characterization

scientific article

The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.

scientific article published in September 2004

The role of Arg(78) in the metabotropic glutamate receptor mGlu(1) for agonist binding and selectivity

scientific article

The use ofXenopusoocytes in drug screening ⬇️

scientific article published on January 18, 2011

Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors

scientific article published on 25 July 2016

Transmembrane α-Helix 2 and 7 Are Important for Small Molecule-Mediated Activation of the GLP-1 Receptor

scientific article published on 30 November 2011

Tweaking agonist efficacy at N-methyl-D-aspartate receptors by site-directed mutagenesis.

scientific article published on 30 August 2005

Xenopus oocyte electrophysiology in GPCR drug discovery

scientific article published in January 2009

cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors

scientific article published on 01 January 2013

mGluR5: exploration of orthosteric and allosteric ligand binding pockets and their applications to drug discovery

scientific article

α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

scientific article

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