List of works by Enzo Lalli

5th International ACC Symposium: An Outlook to Current and Future Research on the Biology of Adrenocortical Carcinoma: Diagnostic and Therapeutic Applications

scientific article published on 14 December 2015

A direct role of SRY and SOX proteins in pre-mRNA splicing

scientific article

A matter of dosage: SF-1 in adrenocortical development and cancer

scientific article published on 17 March 2009

A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita

scientific article

Adrenal cancer: clinical advances.

scientific article published in December 2011

Adrenal cancer: scientific advances

scientific article published on 15 November 2011

Adrenal cortex ontogenesis

scientific article published on December 2010

Adrenal cortex remodeling and functional zona glomerulosa hyperplasia in primary aldosteronism

scientific article published on 11 October 2010

Adrenocortical development and cancer: focus on SF-1.

scientific article published on 03 March 2010

Aldosterone-Producing Adenoma Formation in the Adrenal Cortex Involves Expression of Stem/Progenitor Cell Markers

article published in 2011

Amplification of the steroidogenic factor 1 gene in childhood adrenocortical tumors

scientific article published on 16 November 2004

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

scientific article

Assessment of VAV2 Expression Refines Prognostic Prediction in Adrenocortical Carcinoma.

scientific article

Beyond steroidogenesis: novel target genes for SF-1 discovered by genomics

scientific article

CO-34: Retinoic acid receptor signaling contributes to adrenal morphology and functional zonation

CREM: a master-switch in the transcriptional response to cAMP.

scientific article

Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

scientific article published on 14 March 2020

Clinical and molecular evidence for DAX-1 inhibition of steroidogenic factor-1-dependent ACTH receptor gene expression

scientific article published in May 2005

Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility?

scientific article

Commercial serum-free media: hybridoma growth and monoclonal antibody production

scientific article

DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma

scientific article published on 13 July 2015

DAX-1 blocks steroid production at multiple levels

scientific article published on October 1998

DAX-1 expression in human adrenocortical neoplasms: implications for steroidogenesis

scientific article published in July 1998

DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation

scientific article

DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells

scientific article

DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

scientific article

DNA ploidy analysis of squamous cell carcinomas of the oral and maxillofacial region: clinical and pathologic correlations

scientific article published on 01 September 1996

Dax-1 knockdown in mouse embryonic stem cells induces loss of pluripotency and multilineage differentiation

scientific article

Diagnostic and prognostic role of steroidogenic factor 1 in adrenocortical carcinoma: a validation study focusing on clinical and pathologic correlates

scientific article published on 14 November 2012

Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells

scientific article published on 30 October 2008

Dkk3 is a component of the genetic circuitry regulating aldosterone biosynthesis in the adrenal cortex

scientific article published on 23 August 2012

Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion.

scientific article

Dysregulation of microRNAs in adrenocortical tumors

scientific article published on 02 October 2011

E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis

scientific article

ER-mitochondria contacts find their FATE.

scientific article published on 11 August 2016

ER-mitochondria interactions: Both strength and weakness within cancer cells

scientific article published on 19 January 2019

Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma

scientific article published on 31 August 2012

Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

scientific article published on 7 April 2017

Extracellular matrix and hormones modulate DAX-1 localization in the human fetal adrenal gland

scientific article published on 14 June 2005

FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria

scientific article published on 11 July 2016

FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure

scientific article

Fascin-1 Is a Novel Prognostic Biomarker Associated With Tumor Invasiveness in Adrenocortical Carcinoma

scientific article published on 01 May 2019

Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure ⬇️

scientific journal article

Gene expression profiling of childhood adrenocortical tumors

scientific article published on 01 January 2007

Genetics and genomics of childhood adrenocortical tumors

scientific article

Genome-wide paternal uniparental disomy as a cause of Beckwith-Wiedemann syndrome associated with recurrent virilizing adrenocortical tumors

scientific article published on 03 November 2014

Genomic analysis of sexual dimorphism of gene expression in the mouse adrenal gland

scientific article

Gonadotropin-dependent precocious puberty in a patient with X-linked adrenal hypoplasia congenita caused by a novel DAX-1 mutation

scientific article published on 22 October 2010

Heat shock affects trafficking of DAX-1 by inducing its rapid and reversible cytoplasmic localization

scientific article published in November 2005

Heat shock interferes with steroidogenesis by reducing transcription of the steroidogenic acute regulatory protein gene

scientific article published on August 2001

Heterozygous TP53stop146/R72P fibroblasts from a Li-Fraumeni syndrome patient with impaired response to DNA damage.

scientific article published in April 2010

High frequency of loss of heterozygosity at 11p15 and IGF2 overexpression are not related to clinical outcome in childhood adrenocortical tumors positive for the R337H TP53 mutation

scientific article published on October 2008

Hormonal and developmental regulation of DAX-1 expression in Sertoli cells

scientific journal article

How genomic studies have improved our understanding of the mechanisms of transcriptional regulation by NR5A nuclear receptors

scientific article

Identity by descent mapping of founder mutations in cancer using high-resolution tumor SNP data

scientific article

Impact of ACTH Signaling on Transcriptional Regulation of Steroidogenic Genes

scientific article

Impact of neonatal screening and surveillance for the TP53 R337H mutation on early detection of childhood adrenocortical tumors

scientific article

In situ hybridization in suspension and flow cytometry as a tool for the study of gene expression

scientific article published on December 1992

Increased incidence of choroid plexus carcinoma due to the germline TP53 R337H mutation in southern Brazil

scientific article published on 22 March 2011

Increased serum concentrations of tumour necrosis factor in beta thalassaemia: effect of bone marrow transplantation

scientific article published on January 1992

Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer

scientific article published on 30 August 2007

Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor

scientific article published in December 1993

Inhibition of Adrenocortical Carcinoma Cell Proliferation by Steroidogenic Factor-1 Inverse Agonists.

scientific article published in May 2009

Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists

scientific article published on 24 March 2009

Integrative analysis of SF-1 transcription factor dosage impact on genome-wide binding and gene expression regulation

scientific article published on August 2013

Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis

scientific article

Lack of long-lasting effects of mitotane adjuvant therapy in a mouse xenograft model of adrenocortical carcinoma

scientific article published on 30 July 2013

Local Control of Aldosterone Production and Primary Aldosteronism

scientific article

Methodological pitfalls in the study of DAX-1 function

scientific article published on 2 January 2014

Mitotane Revisited: A New Target for an Old Drug

scientific article published on 01 November 2015

Modeling Fragile X syndrome in neurogenesis: An unexpected phenotype and a novel tool for future therapies

scientific article published on 31 January 2017

NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes

scientific article

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells

scientific article

Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors

scientific article

Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA

scientific article

Partial defects in transcriptional activity of two novel DAX-1 mutations in childhood-onset adrenal hypoplasia congenita

article by Paul Laissue et al published November 2006 in Clinical Endocrinology

Pediatric adrenocortical tumors: what they can tell us on adrenal development and comparison with adult adrenal tumors

scientific article

Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cells proliferation

scientific article

Regulation of adrenocortical cardiotonic steroid production by dopamine and PKA signaling

scientific article published on September 2005

Regulation of human MC2-R gene expression by CREB, CREM, and ICER in the adrenocortical cell line Y1.

scientific article published on August 2007

Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors

scientific article

Regulation of niemann-pick c1 gene expression by the 3'5'-cyclic adenosine monophosphate pathway in steroidogenic cells

scientific article published on 16 January 2003

SF-1 overexpression in childhood adrenocortical tumours

scientific article published on 29 March 2006

SNP array profiling of childhood adrenocortical tumors reveals distinct pathways of tumorigenesis and highlights candidate driver genes.

scientific article published on 26 April 2012

Serum amyloid A protein concentration in bone marrow transplantation for beta thalassaemia

scientific article published on April 1992

Serum markers of immune activation and liver allograft rejection

scientific article published on 01 July 1992

Severe hyperaldosteronism in neonatal Task3 potassium channel knockout mice is associated with activation of the intraadrenal renin-angiotensin system

scientific article published on 22 May 2013

Sexy splicing: regulatory interplays governing sex determination from Drosophila to mammals

scientific article

Signal transduction and gene regulation: the nuclear response to cAMP.

scientific article

Small non-coding RNAs in endocrinology

scientific article published in November 2017

Spatial trends in congenital malformations and stream water chemistry in Southern Brazil

article

Special issue on animal models in endocrine neoplasia.

scientific article published in February 2016

Specific immunoassays for placental alkaline phosphatase as a tumor marker

scientific article

Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development

scientific article published in October 1996

Steroidogenic factor-1 gene dose and adrenocortical tumors

article

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

scientific article published in May 2003

Targeting DAX-1 in embryonic stem cells and cancer

scientific article published on February 2010

Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo.

scientific article published on 7 February 2018

Task3 Potassium Channel Gene Invalidation Causes Low Renin and Salt-Sensitive Arterial Hypertension

article

The ER-mitochondria couple: In life and death from steroidogenesis to tumorigenesis

scientific article

The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways.

scientific article published on 20 February 2018

The Prognostic Role of CD8+ T Lymphocytes in Childhood Adrenocortical Carcinomas Compared to Ki-67, PD-1, PD-L1, and the Weiss Score

scientific article published on 05 November 2019

The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells

scientific article

The Wnt/beta-catenin pathway in adrenocortical development and cancer ⬇️

scientific article published on November 20, 2010

The next step: mechanisms driving adrenocortical carcinoma metastasis.

scientific article

The nuclear response to cAMP: role of transcription factor CREM.

scientific article published on February 1996

The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors

scientific article

Therapy of adrenocortical cancer: present and future.

scientific article

Thyroid-stimulating hormone (TSH)-directed induction of the CREM gene in the thyroid gland participates in the long-term desensitization of the TSH receptor

scientific article

Transcriptional regulation of the glucose-6-phosphatase gene by cAMP/vasoactive intestinal peptide in the intestine. Role of HNF4alpha, CREM, HNF1alpha, and C/EBPalpha

scientific journal article

Transcriptional regulation of the mouse steroidogenic acute regulatory protein gene by the cAMP response-element binding protein and steroidogenic factor 1.

scientific article

Two-pore domain potassium channels in the adrenal cortex

scientific article published on 23 October 2014

VAV2: a novel prognostic marker and a druggable target for adrenocortical carcinoma

scientific article published on 2 October 2017

Vanin-1 inactivation antagonizes the development of adrenocortical neoplasia in Sf-1 transgenic mice.

scientific article published on 8 April 2014

X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein

scientific article

XAF1 as a modifier of p53 function and cancer susceptibility

scientific article published on 24 June 2020

[OP.3A.02] RETINOIC ACID RECEPTOR SIGNALING CONTRIBUTES TO ADRENAL CORTEX MORPHOLOGY AND FUNCTIONAL ZONATION

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