List of works - Kaare Teilum

(S)Pinning down protein interactions by NMR.

scientific article published on 26 December 2016

A Folded Excited State of Ligand-Free Nuclear Coactivator Binding Domain (NCBD) Underlies Plasticity in Ligand Recognition

scientific article published in 2013

A Soluble, Folded Protein without Charged Amino Acid Residues

scientific article

A dual-reporter system for investigating and optimizing protein translation and folding in E. coli

scientific article published on 19 October 2021

Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.

scientific article

Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

scientific article published on 11 March 2016

Application of Hydrogen Exchange Kinetics to Studies of Protein Folding

Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification

scientific article

Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness

scientific article

Biosynthetic 13C labeling of aromatic side chains in proteins for NMR relaxation measurements

scientific article published in March 2006

Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP

scientific article

Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein

scientific article published in March 2004

Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles

scientific article published on 01 April 2005

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

scientific article (publication date: 24 January 2017)

Disulfide Bond Formation and Folding of Plant Peroxidases Expressed as Inclusion Body Protein inEscherichia coliThioredoxin Reductase Negative Strains

article

Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing

scientific article

Fitting Side-Chain NMR Relaxation Data Using Molecular Simulations

scientific article published on 22 July 2021

Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP.

scientific article published in September 2000

Fractional 13C enrichment of isolated carbons using [1-13C]- or [2-13C]-glucose facilitates the accurate measurement of dynamics at backbone Cα and side-chain methyl positions in proteins

article

Functional aspects of protein flexibility.

scientific article

Globular and disordered-the non-identical twins in protein-protein interactions

scientific article published on 9 July 2015

Helical Propensity in an Intrinsically Disordered Protein Accelerates Ligand Binding

Is a malleable protein necessarily highly dynamic? The hydrophobic core of the nuclear coactivator binding domain is well ordered

scientific article

Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

scientific article published on 03 January 2019

Millisecond Dynamics in Glutaredoxin during Catalytic Turnover Is Dependent on Substrate Binding and Absent in the Resting States

article

Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs

scientific article published on 04 July 2018

NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.

scientific article

Non-uniform sampling of NMR relaxation data

scientific article

Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection

scientific article published on 5 April 2014

Protein dielectric constants determined from NMR chemical shift perturbations

scientific article

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

scientific article

Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.

scientific article

Protein stability, flexibility and function ⬇️

scientific article published on November 19, 2010

Purification, crystallization and preliminary X-ray diffraction analysis of the carbohydrate-binding domain of flocculin, a cell-adhesion molecule from Saccharomyces carlsbergensis

scientific article published on 23 November 2002

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

scholarly article by Jeppe T. Pedersen et al published 17 February 2011 in Angewandte Chemie International Edition

Remeasuring HEWL pK(a) values by NMR spectroscopy: methods, analysis, accuracy, and implications for theoretical pK(a) calculations

scientific article

Software for reconstruction of non-uniformly sampled NMR data

scientific article published on 09 June 2020

Solution Structure of Human Prolactin

scientific article published on 01 August 2005

Solution structures of human and porcine beta-microseminoprotein

scientific article

Structure of Dimeric and Tetrameric Complexes of the BAR Domain Protein PICK1 Determined by Small-Angle X-Ray Scattering

scientific article published on 11 June 2015

Structure of soybean seed coat peroxidase: A plant peroxidase with unusual stability and haem-apoprotein interactions

scientific article

Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae.

scientific article published on 28 June 2017

The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor

scientific article published on 09 May 2019

The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ -Aβ Complex.

scientific article published on 16 August 2017

The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

scientific article

The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications

scientific article published on 6 July 2017

The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region

scientific article published on 14 June 2012

The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein

scholarly article

The pKa Value and Accessibility of Cysteine Residues Are Key Determinants for Protein Substrate Discrimination by Glutaredoxin

scientific article published in 2014

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

scientific article published on 11 April 2019

Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH.

scientific article

Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization

scientific article published on 14 October 2009

Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling

scientific article published in November 2002

relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data.

scientific article

List of works by Kaare Teilum

(S)Pinning down protein interactions by NMR.

A Folded Excited State of Ligand-Free Nuclear Coactivator Binding Domain (NCBD) Underlies Plasticity in Ligand Recognition

A Soluble, Folded Protein without Charged Amino Acid Residues

A dual-reporter system for investigating and optimizing protein translation and folding in E. coli

Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.

Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing

Application of Hydrogen Exchange Kinetics to Studies of Protein Folding

Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification

Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness

Biosynthetic 13C labeling of aromatic side chains in proteins for NMR relaxation measurements

Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP

Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein

Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

Disulfide Bond Formation and Folding of Plant Peroxidases Expressed as Inclusion Body Protein inEscherichia coliThioredoxin Reductase Negative Strains

Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing

Fitting Side-Chain NMR Relaxation Data Using Molecular Simulations

Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP.

Fractional 13C enrichment of isolated carbons using [1-13C]- or [2-13C]-glucose facilitates the accurate measurement of dynamics at backbone Cα and side-chain methyl positions in proteins

Functional aspects of protein flexibility.

Globular and disordered-the non-identical twins in protein-protein interactions

Helical Propensity in an Intrinsically Disordered Protein Accelerates Ligand Binding

Is a malleable protein necessarily highly dynamic? The hydrophobic core of the nuclear coactivator binding domain is well ordered

Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

Millisecond Dynamics in Glutaredoxin during Catalytic Turnover Is Dependent on Substrate Binding and Absent in the Resting States

Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs

NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.

Non-uniform sampling of NMR relaxation data

Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection

Protein dielectric constants determined from NMR chemical shift perturbations

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.

Protein stability, flexibility and function ⬇️

Purification, crystallization and preliminary X-ray diffraction analysis of the carbohydrate-binding domain of flocculin, a cell-adhesion molecule from Saccharomyces carlsbergensis

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

Remeasuring HEWL pK(a) values by NMR spectroscopy: methods, analysis, accuracy, and implications for theoretical pK(a) calculations

Software for reconstruction of non-uniformly sampled NMR data

Solution Structure of Human Prolactin

Solution structures of human and porcine beta-microseminoprotein

Structure of Dimeric and Tetrameric Complexes of the BAR Domain Protein PICK1 Determined by Small-Angle X-Ray Scattering

Structure of soybean seed coat peroxidase: A plant peroxidase with unusual stability and haem-apoprotein interactions

Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae.

The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor

The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ -Aβ Complex.

The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications

The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region

The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein

The pKa Value and Accessibility of Cysteine Residues Are Key Determinants for Protein Substrate Discrimination by Glutaredoxin

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH.

Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization

Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling

relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data.