List of works - Cindy S Ma

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

scientific article published on 01 April 2011

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

scientific article published on 01 June 2018

A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR(-) B cells.

scientific article

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells

scientific article published on 06 February 2019

An essential role for the Zn2+ transporter ZIP7 in B cell development

scientific article published on 04 February 2019

Automatic generation of lymphocyte heterogeneity: Division-dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4+ T cells are independently regulated

scientific article published in February 2004

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects

scientific article published on 20 February 2019

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

scientific article

CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses

scientific article published on 6 April 2011

Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia

scientific article published on 11 October 2018

Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β

scientific article published on 01 November 2019

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

scientific article published on October 2013

Combined Immunodeficiency with Ring Chromosome 21.

scientific article published on 15 April 2018

Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk

article

Correction to: Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia

scientific article published on 01 November 2018

Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.

scientific article

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

scientific article published in December 2007

DOCK8 Drives Src-Dependent NK Cell Effector Function

scientific article published on 9 August 2017

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

scientific article

DOCK8 is critical for the survival and function of NKT cells

scientific article published on 08 August 2013

Dedicator of cytokinesis 8-deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells.

scientific article published on 20 August 2016

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

scientific article published on July 2008

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency

scientific article published on 20 August 2018

Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.

scientific article published on 19 September 2016

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

scientific article published in September 2009

Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM+IgD+CD27+ B cells harbor the virus in X-linked lymphoproliferative disease patients

scientific article published on 28 May 2008

Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus.

scientific article

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production

scientific article published on 12 May 2015

Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity

scientific article published on 04 September 2019

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

scientific article

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

scientific article

Germline-activating mutations in PIK3CD compromise B cell development and function

scientific article published on 17 July 2018

Helper T cell immunity in humans with inherited CD4 deficiency

scientific article published in 2024

Helping the Helpers!

scientific article published on 01 July 2009

Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients

scientific article published on 25 April 2019

Here, there and everywhere: T follicular helper cells on the move

scientific article

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

scientific article published on 01 December 2018

Human T Follicular Helper Cells in Primary Immunodeficiency: Quality Just as Important as Quantity

scientific article published on 10 March 2016

Human T follicular helper (Tfh) cells and disease

scientific article published on 22 October 2013

Human T follicular helper cells in primary immunodeficiencies

scientific article published on December 2014

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

scientific article

Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21

scientific article published on 08 June 2010

Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP

scientific article published on 08 March 2019

Human plasma C3 is essential for the development of memory B, but not T, lymphocytes.

scientific article

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts.

scientific article published on 24 October 2013

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

scientific article published in August 2008

IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice

scientific article published on 12 September 2016

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells. ⬇️

scientific article

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

scientific article

IRF4 haploinsufficiency in a family with Whipple's disease.

scientific article

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

article

Immunology: Cytotoxic T cells that escape exhaustion.

scientific article published on 24 August 2016

Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child

scientific article published on 28 June 2021

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

scientific article published in Nature Communications

Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP

scientific article published on 23 May 2006

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

scientific article published on 07 July 2015

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

scientific article

OMIP-063: 28-Color Flow Cytometry Panel for Broad Human Immunophenotyping

scientific article published on 16 April 2020

Regulation of NKT cell development by SAP, the protein defective in XLP

scientific article published on 13 February 2005

Regulation of T follicular helper cell formation and function by antigen presenting cells.

scientific article

Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.

scientific article

Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency

scientific article

STAT3 is a central regulator of lymphocyte differentiation and function.

scientific article published on 06 March 2014

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

scientific article published on 4 May 2015

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells

scientific article published on 25 June 2008

STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles

scientific article published on 23 February 2018

Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

scientific article

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses

scientific article published on 7 February 2018

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

scientific article published on 04 July 2013

T cell-B cell interactions in primary immunodeficiencies

scientific article published on 30 January 2012

The FOXP3Δ2 isoform supports Treg cell development and protects against severe IPEX syndrome

scientific article published on 21 March 2019

The circulating life of a memory T-follicular helper cell

scientific article published on 19 May 2017

The good, the bad and the ugly - TFH cells in human health and disease

scientific article published on 17 May 2013

The origins, function, and regulation of T follicular helper cells ⬇️

scientific article published on July 2, 2012

The regulation and role of T follicular helper cells in immunity ⬇️

scientific article published on December 1, 2011

The role of SAP and SLAM family molecules in the humoral immune response ⬇️

scientific article published on November 22, 2010

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment

scientific article published on 23 July 2009

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common missense variant

scientific article published on 01 December 2018

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.

scientific article published on 11 July 2016

What can primary immunodeficiencies teach us about Th9 cell differentiation & function?

scientific article published on 19 November 2018

List of works by Cindy S Ma

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR(-) B cells.

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells

An essential role for the Zn2+ transporter ZIP7 in B cell development

Automatic generation of lymphocyte heterogeneity: Division-dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4+ T cells are independently regulated

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses

Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia

Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

Combined Immunodeficiency with Ring Chromosome 21.

Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk

Correction to: Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia

Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

DOCK8 Drives Src-Dependent NK Cell Effector Function

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

DOCK8 is critical for the survival and function of NKT cells

Dedicator of cytokinesis 8-deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells.

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency

Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM+IgD+CD27+ B cells harbor the virus in X-linked lymphoproliferative disease patients

Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus.

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production

Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

Germline-activating mutations in PIK3CD compromise B cell development and function

Helper T cell immunity in humans with inherited CD4 deficiency

Helping the Helpers!

Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients

Here, there and everywhere: T follicular helper cells on the move

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

Human T Follicular Helper Cells in Primary Immunodeficiency: Quality Just as Important as Quantity

Human T follicular helper (Tfh) cells and disease

Human T follicular helper cells in primary immunodeficiencies

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21

Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP

Human plasma C3 is essential for the development of memory B, but not T, lymphocytes.

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts.

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells. ⬇️

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

IRF4 haploinsufficiency in a family with Whipple's disease.

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

Immunology: Cytotoxic T cells that escape exhaustion.

Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

OMIP-063: 28-Color Flow Cytometry Panel for Broad Human Immunophenotyping

Regulation of NKT cell development by SAP, the protein defective in XLP

Regulation of T follicular helper cell formation and function by antigen presenting cells.

Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.

Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency

STAT3 is a central regulator of lymphocyte differentiation and function.

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells

STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles

Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

T cell-B cell interactions in primary immunodeficiencies

The FOXP3Δ2 isoform supports Treg cell development and protects against severe IPEX syndrome

The circulating life of a memory T-follicular helper cell

The good, the bad and the ugly - TFH cells in human health and disease

The origins, function, and regulation of T follicular helper cells ⬇️

The regulation and role of T follicular helper cells in immunity ⬇️

The role of SAP and SLAM family molecules in the humoral immune response ⬇️

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common missense variant

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.