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List of works by Angelo Corti

A new chromogranin A-dependent angiogenic switch activated by thrombin

scientific article published on 27 November 2012

A pilot Phase I study combining peptide-based vaccination and NGR-hTNF vessel targeting therapy in metastatic melanoma

scientific article

A rapid method for monitoring DNA labelling reactions with haptens

scientific article published in November 1990

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

scientific article published on 01 December 2019

Affinity enhancement of complementary peptide recognition

scientific article published on 01 June 1992

Altered chromogranin A circulating levels in Meniere's disease

scientific article published on 23 April 2015

Angiopoietin-2 in Bone Marrow milieu promotes Multiple Myeloma-associated angiogenesis

scientific article published on 24 October 2014

Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A.

scientific article

Antigenic Regions of Human Chromogranin A and their Topographic Relationships with Structural/Functional Domains

scientific article published on 01 January 1996

Antigenic regions of tumor necrosis factor alpha and their topographic relationships with structural/functional domains

scientific article published on April 1992

Approaches to improve tumor accumulation and interactions between monoclonal antibodies and immune cells

scientific article

Autocrine saturation of pro-urokinase receptors on human A431 cells

scientific article published in June 1986

Binding of human tumor necrosis factor α to multimeric complementary peptides

scientific article published on 01 July 1992

Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli

scientific article

Biotinylation sites of tumor necrosis factor-alpha determined by liquid chromatography-mass spectrometry

scientific article published in November 2001

Bone marrow-derived CD13(+) cells sustain tumor progression: A potential non-malignant target for anticancer therapy

scientific article published on 16 January 2014

CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis

scientific article published on 02 December 2013

Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production Leading to Improved Insulin Sensitivity.

scientific article published on 6 February 2018

Ceruloplasmin functional changes in Parkinson's disease-cerebrospinal fluid

scientific article published on 4 November 2015

CgA in heart diseases: more than meets the eye

scientific article published on 20 September 2013

Characterisation of functional biotinylated TNF-alpha targeted to the membrane of apoptotic melanoma cells

scientific article published in May 2003

Characterization of natural vasostatin-containing peptides in rat heart

scientific article published on 01 July 2006

Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients

scientific article published on 11 February 2016

Chromogranin A N-terminal fragments vasostatin-1 and the synthetic CGA 7-57 peptide act as cardiostatins on the isolated working frog heart

scientific article published in April 2004

Chromogranin A and derived peptides in health and disease

scientific article

Chromogranin A and the Tumor Microenvironment ⬇️

scientific article published on November 16, 2010

Chromogranin A and the endothelial barrier function

scientific article published on January 2012

Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice

scientific article published on 14 March 2012

Chromogranin A fragments modulate cell adhesion. Identification and characterization of a pro-adhesive domain

scientific article published on August 1997

Chromogranin A in Tumors: More Than a Marker for Diagnosis and Prognosis

Chromogranin A in heart failure; a novel neurohumoral factor and a predictor for mortality.

scientific article

Chromogranin A induces a neurotoxic phenotype in brain microglial cells

scientific article published in June 1998

Chromogranin A regulates tumor self-seeding and dissemination

scientific article

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

scientific article

Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy.

scientific article

Chromogranin A: a paradoxical player in angiogenesis and vascular biology

scientific article

Chromogranin-A production and fragmentation in patients with Takayasu arteritis

scientific article published on 17 August 2016

Circulating chromogranin A and its fragments as diagnostic and prognostic disease markers.

scientific article

Circulating chromogranin A reveals extra-articular involvement in patients with rheumatoid arthritis and curbs TNF- -elicited endothelial activation

article

Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion

scientific article

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

scientific article published on 24 March 2010

Commentary: granins, secretory granule biogenesis, and transport

scientific article published in October 2012

Comparison of the solid phase enzyme receptor assay (SPERA) and the microbiological assay for teicoplanin

scientific article published on 01 March 1986

Conversation galante: how the immune and the neuroendocrine systems talk to each other

scientific article published on 28 March 2007

Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity

scientific article published on January 2004

Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

scientific article published on 11 January 2010

Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgamma

scientific article

Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin

scientific article

Crucial role of cytoskeleton reorganization in the negative inotropic effect of chromogranin A-derived peptides in eel and frog hearts

Cytoskeleton mediates negative inotropism and lusitropism of chromogranin A-derived peptides (human vasostatin1-78 and rat CgA₁₋₆₄) in the rat heart.

scientific article

Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours

Development of an immunoassay for the derived-peptide of chromogranin A, Vasostatin-I (1-76): assessment of severity in patients with sepsis

article

Effect of bench-scale culture conditions on murine IgG heterogeneity

scientific article published on April 1997

Effect of chromogranin A-derived vasostatin-1 on laser-induced choroidal neovascularization in the mouse

scientific article

Effects of the tumor vasculature targeting agent NGR-TNF on the tumor microenvironment in murine lymphomas

scientific article published in January 2006

Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin

scientific article

Enhanced expression of CD13 in vessels of inflammatory and neoplastic tissues

scientific article published on January 2011

Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).

scientific article

Epitope mapping of human chromogranin A by peptide microarrays

scientific article published on January 2009

Evidences that syngeneic alpha-type anti-idiotypic antibodies may non-competitively inhibit idiotype/oligomeric antigen interactions by affecting idiotype avidity

scientific article published on 01 August 1993

Full-length human chromogranin-A cardioactivity: myocardial, coronary, and stimulus-induced processing evidence in normotensive and hypertensive male rat hearts

scientific article published on 10 June 2013

Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing

scientific article published on September 2017

Granin-derived peptides

scientific article

High blood levels of chromogranin A in giant cell arteritis identify patients refractory to corticosteroid treatment.

scientific article published in February 2009

How to improve exposure of tumor cells to drugs: promoter drugs increase tumor uptake and penetration of effector drugs.

scientific article published on 29 September 2011

Human Recombinant Vasostatin-1 May Interfere with Cell-Extracellular Matrix Interactions

scientific article published on 01 December 2006

Human recombinant chromogranin A-derived vasostatin-1 mimics preconditioning via an adenosine/nitric oxide signaling mechanism

scientific article published on 06 April 2007

Identification of Two Forms (31-33 and 48 kD) of the Urinary Soluble p55 Tumor Necrosis Factor Receptor That Are Differentially N- and O-Glycosylated

scholarly article by Angelo Corti published in February 1995

Idiotope determining regions of a mouse monoclonal antibody and its humanized versions

scientific article published on 01 January 1994

Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif

Immunomodulatory Agents with Antivascular Activity in the Treatment of Non-Small Cell Lung Cancer: Focus on TLR9 Agonists, IMiDs and NGR-TNF.

scientific article

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

article

Improving drug penetration to curb tumor drug resistance.

scientific article published on 15 June 2012

Improving drug uptake and penetration into tumors: current and forthcoming opportunities.

scientific article published on 18 June 2013

Increased low-grade inflammation is associated with lack of functional response to carvedilol in patients with systolic heart failure

scientific article published in January 2013

Induction of functional inducible nitric oxide synthase in monocytes of patients with congestive heart failure. Link with tumour necrosis factor-α

scientific article published on 01 October 1999

Influence of vasostatins, the chromogranin A-derived peptides, on the working heart of the eel (Anguilla anguilla): negative inotropy and mechanism of action

scientific article published in October 2004

Inhibition of chronic lymphocytic leukemia progression by full-length chromogranin A and its N-terminal fragment in mouse models

scientific article published on 17 May 2016

Inhibition of tumor growth by intramuscular injection of cDNA encoding tumor necrosis factor alpha coupled to NGR and RGD tumor-homing peptides

scientific article published in April 2004

Inhibitory influence of chromogranin A N-terminal fragment (vasostatin-1) on the spontaneous contractions of rat proximal colon

scientific article published in August 2005

Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine

scientific article published on 30 January 2006

Inverse polymerase chain reaction for cloning complete human immunoglobulin variable regions and leaders conserving the original sequence

scientific article published in July 1996

IsoDGR-tagged albumin: a new αvβ3 selective carrier for nanodrug delivery to tumors

scientific article published on 12 November 2012

Isoaspartate-dependent molecular switches for integrin–ligand recognition ⬇️

scientific article published on February 15, 2011

Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif

scientific article published in September 2008

Kinetic analysis of TNF-alpha oligomer-monomer transition by surface plasmon resonance and immunochemical methods

scientific article published in November 1993

Liposome-mediated therapy of neuroblastoma

scientific article published in January 2009

Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout

scientific article

Mode of Interaction Between Tumor Necrosis Factor α and a Monoclonal Antibody Expressing a Recurrent Idiotype

scholarly article by ELENA BARBANTI et al published February 1993 in Hybridoma

Mode of interaction between a monoclonal antibody and human TNFα

scientific article published on 01 September 1992

Monoclonal antibodies to human urokinase identify the single-chain pro-urokinase precursor ⬇️

scientific article published on January 1, 1984

Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice.

scientific article

Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function

scientific article published on 27 March 2007

NF-kappa B-mediated regulation of urokinase gene expression by PMA and TNF-alpha in human A549 cells

scientific article published on September 1996

NGR-tagged nano-gold: A new CD13-selective carrier for cytokine delivery to tumors

scientific article published on 04 March 2016

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion

scientific article published on August 2015

Neuroendocrine Modulation Induced by Selective Blockade of TNF- in Rheumatoid Arthritis

scientific article published on 01 June 2006

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

scientific article

Oligomeric tumour necrosis factor alpha slowly converts into inactive forms at bioactive levels

scientific article

Oral direct thrombin inhibition: a double-edged sword?

scientific article

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

scientific article published on 01 October 1999

Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling

scientific article published on 23 December 2013

Oxidative stress biomarkers and chromogranin A in uremic patients: Effects of dialytic treatment

scientific article published in 2010

PCR amplification of antibody variable regions using primers that anneal to constant regions.

scientific article published on May 1994

Peptide microarrays for the characterization of antigenic regions of human chromogranin A.

scientific article published in September 2005

Peptide-mediated targeting of cytokines to tumor vasculature: the NGR-hTNF example.

scientific article published on December 2013

Plasma Chromogranin A as a marker of cardiovascular involvement in Erdheim-Chester disease

scientific article

Plasma levels of vasostatin-1, a chromogranin A fragment, are associated with carotid artery maximum stenosis: A pilot study

scientific article published on 6 February 2017

Post cardiac surgery diaphragmatic spasm successfully treated with gabapentin

scientific article published on 9 June 2005

Processing of chromogranins/secretogranin in patients with diabetic retinopathy

scientific article published on 24 December 2010

Production and Structure Characterization of Recombinant Chromogranin A N-Terminal Fragments (Vasostatins). Evidence of Dimmer-Monomer Equilibria

article

Production and characterisation of human recombinant single chain urokinase-type plasminogen activator from mouse cells

article

Production of Soluble Tumor Necrosis Factor Receptor Type I in Escherichia coli: Optimization of the Refolding Yields by a Microtiter Dilution Assay

article

Prognostic value of circulating chromogranin A and soluble tumor necrosis factor receptors in advanced nonsmall cell lung cancer

Pushing tumor cells towards a malignant phenotype: stimuli from the microenvironment, intercellular communications and alternative roads

scientific article

R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma

scientific article published on 22 May 2019

Recombinant N-terminal fragments of chromogranin-A modulate cardiac function of the Langendorff-perfused rat heart

scientific article

Regulation of tumor growth by circulating full-length chromogranin A.

scientific article published on 24 September 2016

Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.

scientific article published on 9 March 2010

Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.

scientific article

Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors

scientific article published on 8 February 2016

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement

scientific article published on 22 February 2019

Spontaneous formation of L-isoaspartate and gain of function in fibronectin.

scientific article published on 2 October 2006

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

scientific article

Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells

scientific article published on September 2000

Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif

scientific article published on 7 October 2002

Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha

scientific article published in January 2006

Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha

scientific article published in February 2008

Synthesis and characterization of D-Alanyl-D-Alanine-Agarose

scientific article published in 1985

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

scientific article

TNF-α in Erdheim-Chester disease pericardial effusion promotes endothelial leakage in vitro and is neutralized by infliximab

scientific article published on 26 July 2013

Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms

scientific article

Targeted drug delivery and penetration into solid tumors

scientific article published on February 2011

Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression

scientific article published on 10 February 2016

Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy

scientific article published on 08 February 2012

Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy

scientific article published on 28 February 2018

Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy

scientific article published on October 2006

Teicoplanin, a new antibiotic from Actinoplanes teichomyceticus nov. sp. ⬇️

scientific article

The N-terminal fragment of chromogranin A, vasostatin-1 protects mice from acute or chronic colitis upon oral administration.

scientific article published on 26 January 2012

The chromogranin A peptide vasostatin-I inhibits gap formation and signal transduction mediated by inflammatory agents in cultured bovine pulmonary and coronary arterial endothelial cells

scientific article published on 24 May 2006

The chromogranin A- derived N-terminal peptide vasostatin-I: In vivo effects on cardiovascular variables in the rabbit

The endocrine role for chromogranin A: a prohormone for peptides with regulatory properties.

scientific article published on November 2007

The neovasculature homing motif NGR: more than meets the eye.

scientific article published on 23 June 2008

The three-step pretargeting approach reduces the human anti-mouse antibody response in patients submitted to radioimmunoscintigraphy and radioimmunotherapy

article

The vasostatin-1 fragment of chromogranin A preserves a quiescent phenotype in hypoxia-driven endothelial cells and regulates tumor neovascularization

scientific article

The vasostatin-I fragment of chromogranin A inhibits VEGF-induced endothelial cell proliferation and migration

scientific article

Tumor Necrosis Factor (TNF) α quantification by ELISA and bioassay: effects of TNFα-soluble TNF receptor (p55) complex dissociation during assay incubations

scientific article published on 01 December 1994

Tumor Necrosis Factor Soluble Receptors in Patients With Various Degrees of Congestive Heart Failure

scientific article published on 01 September 1995

Tumor Necrosis Factor α As a Master Regulator of Inflammation in Erdheim-Chester Disease: Rationale for the Treatment of Patients With Infliximab

Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems ⬇️

scientific article published on August 1, 2011

Tumor cell-associated immune checkpoint molecules - Drivers of malignancy and stemness

scientific article published on 19 October 2017

Tumor necrosis factor alpha and its receptors in relapsing-remitting multiple sclerosis

scientific article

Tumor necrosis factor in congestive heart failure: A mechanism of disease for the new millennium?

scientific article published on 01 July 1998

Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs

scientific article

Vascular attack and immunotherapy: a 'two hits' approach to improve biological treatment of cancer

scientific article published in February 1999

Vascular targeting, chemotherapy and active immunotherapy: teaming up to attack cancer

scientific article published on 28 March 2008

Vasculature-targeted tumor necrosis factor-alpha increases the therapeutic index of doxorubicin against prostate cancer

scientific article published in July 2008

Vasostatin-1: A novel circulating biomarker for ileal and pancreatic neuroendocrine neoplasms.

scientific article published on 3 May 2018

Vasostatin-I, a chromogranin A-derived peptide, in non-selected critically ill patients: distribution, kinetics, and prognostic significance

Won’t you come on in? How to favor lymphocyte infiltration in tumors ⬇️

scientific article published on September 1, 2012

pGlu-serpinin protects the normotensive and hypertensive heart from ischemic injury

scientific article

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