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List of works by Michael Hudecek

A highly soluble Sleeping Beauty transposase improves control of gene insertion

scientific article published on 04 November 2019

Adoptive T-cell therapy for B-cell malignancies

scientific article published on October 2009

Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition

scientific article published on March 2014

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

scientific article published on 25 April 2016

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

scientific article

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen ⬇️

scientific article published on April 23, 2012

Development of tumor-reactive T cells after nonmyeloablative allogeneic hematopoietic stem cell transplant for chronic lymphocytic leukemia

scientific article published on 30 June 2009

Engineered T cells for anti-cancer therapy.

scientific article published on 18 July 2012

Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors

scientific article published on 5 August 2016

Expression of programmed death-1 on lymphocytes in myeloma patients is lowered during lenalidomide maintenance

scientific article published on 30 November 2017

Immunotherapy of non-Hodgkin's lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor-modified T cells

scientific article published on September 2016

Inefficient CAR-proximal signaling blunts antigen sensitivity

scientific article published on 06 July 2020

Kleine Antigene – große Wirkung

scientific article published on 01 July 2008

Mesenchymal Stem Cells Remain Host-Derived Independent of the Source of the Stem-Cell Graft and Conditioning Regimen Used

scientific article published on 01 January 2009

Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells.

scientific article published on January 2016

Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility

scientific article published on 14 August 2017

Myeloma CARs are rolling into the clinical arena

scientific article published on 01 September 2016

Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab

scientific article published on 05 May 2017

Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells

scientific article published on 25 April 2013

Recognition and killing of brain tumor stem-like initiating cells by CD8+ cytolytic T cells.

scientific article published on 10 November 2009

SLAMF7-CAR T cells eliminate myeloma and confer selective fratricide of SLAMF7+ normal lymphocytes

scientific article

Safety of targeting ROR1 for cancer immunotherapy with chimeric antigen receptor-modified T cells in a primate model

scientific article published on 6 November 2014

Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells

scientific article

Spontaneous remission of acute myeloid leukemia relapse after hematopoietic cell transplantation in a high-risk patient with 11q23/MLL abnormality

scientific article published on 27 March 2008

Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia

scientific article published on 17 October 2016

The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.

scientific article

The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity.

scientific article

The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells

scientific article published on 01 July 2019

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