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List of works by Tohru Minamino

A Case of Aortic Regurgitation Presenting with Recurrent Detachment of a Prosthetic Valve, as the First Presenting Symptom of Cardiovascular Behçet's Disease

scientific article published on 8 December 2017

A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis

scientific article

A crucial role for adipose tissue p53 in the regulation of insulin resistance

scientific article published on 30 August 2009

A mutant mRNA expression in an endomyocardial biopsy sample obtained from a patient with a cardiac variant of Fabry disease caused by a novel acceptor splice site mutation in the invariant AG of intron 5 of the α-galactosidase A gene

scientific article published on 01 April 2013

A role for circadian clock in metabolic disease.

scientific article published on 18 February 2016

Adipose tissue inflammation in diabetes and heart failure

scientific article published on 29 October 2012

Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice

scientific article published on 30 January 2012

Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway

scientific article

Akt-induced cellular senescence: implication for human disease

scientific article published in April 2004

Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice

scientific article published on 24 November 2011

Amlodipine Inhibits Vascular Cell Senescence and Protects Against Atherogenesis Through the Mechanism Independent of Calcium Channel Blockade.

scientific article published on 20 April 2018

Angiogenesis, Cancer, and Vascular Aging.

scientific article published on 24 October 2017

Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway

scientific article published on 14 August 2006

Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium

scientific article published on 12 February 2004

Aortic carboxypeptidase-like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis

scientific article published on 19 March 2018

Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy.

scientific article

Atrial Fibrillation in Patients with End-stage Kidney Disease on Dialysis

scientific article published on 30 March 2018

Augmentation of the J wave by rapid pacing in a patient with vasospastic angina

scientific article published on 04 January 2014

Bidirectional Shunt Trajectory in Ventricular Septal Defect With Eisenmenger's Syndrome

scientific article published on 25 May 2018

Boysenberry polyphenol inhibits endothelial dysfunction and improves vascular health

scientific article published in PLoS ONE

Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway

scientific article published on 3 May 2012

Burden of cardiovascular disease in Japanese cancer patients and survivors: a single cancer-center study in Niigata City

scientific article published on 14 September 2018

Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy

scientific article published on 16 August 2010

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

scientific article published on 22 June 2009

Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle

scientific article published on 18 October 2004

Catecholamine-Induced Senescence of Endothelial Cells and Bone Marrow Cells Promotes Cardiac Dysfunction in Mice

scientific article published on 23 May 2018

Cell therapy for cardiovascular diseases

scientific article published on 24 October 2008

Cellular Senescence in Arterial Diseases

scientific article published on 08 January 2020

Cellular senescence impairs circadian expression of clock genes in vitro and in vivo

scientific article published on 19 January 2006

Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients.

scientific article published on 6 February 2015

Cibenzoline Abolished Pulsus Alternans in a HOCM Patient

scientific article published on 01 September 2015

Clinical features and predictors of patients with critical limb ischemia who responded to autologous mononuclear cell transplantation for therapeutic angiogenesis.

scientific article published on 29 March 2017

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scientific article

Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling

scientific article published on 26 February 2015

Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.

scientific article

DNA damage response and metabolic disease.

scientific article

Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue

scientific article published on 18 April 2022

Double outlet right ventricle demonstrated by multislice computed tomography.

scientific article published on 28 November 2006

Dual Antiplatelet Therapy Guided by CYP2C19 Polymorphisms after Implantation of Second-Generation Drug-Eluting Stents for Management of Acute Coronary Syndrome

scientific article

Early repolarization and risk of arrhythmia events in long QT syndrome

scientific article published on 11 August 2016

Effect of a Low-Intensity Pulsed Ultrasound Device, SX-1001, on Clinical Symptoms in Buerger Disease With Limb Ischemia.

scientific article published on 9 November 2015

Effect of heme oxygenase-1 overexpression in two models of lung inflammation

scientific article published on 01 May 2003

Effects of Direct Oral Anticoagulants at the Peak Phase, Trough Phase, and After Vascular Injury

scientific article published in January 2018

Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia.

scientific article published on 31 December 2012

Efficacy and Safety of a Novel Endothelin Receptor Antagonist, Macitentan, in Japanese Patients With Pulmonary Arterial Hypertension.

scientific article

Efficacy of Corticosteroid Treatment for Refractory Multivessel Vasospastic Coronary Angina with Hypereosinophilia.

scientific article

Efficacy of bepridil to prevent ventricular fibrillation in severe form of early repolarization syndrome

scientific article published on 23 January 2014

Electrocardiographic abnormalities and risk of developing cardiac events in extracardiac sarcoidosis

scientific article published on 26 March 2015

Elevated Endomyocardial Biopsy Macrophage-Related Markers in Intractable Myocardial Diseases.

scientific article published on 24 July 2015

Emerging issues in radiogenic cataracts and cardiovascular disease

scientific article

Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

scientific article

Endothelin-converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis

scientific article published on 01 January 1997

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

scientific article published on 19 April 2010

Frequency characteristics and associations with the defibrillation threshold of ventricular fibrillation in patients with implantable cardioverter defibrillators.

scientific article published on 15 May 2015

G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes

scientific article published on 20 February 2005

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity

scientific article published on 01 September 2018

Gap junctions mediate the spread of ischemia-reperfusion injury

scientific article published on 01 September 2009

Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers

scientific article published on 01 December 2017

Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease

scientific article published on 01 April 1997

Genetics of Brugada syndrome.

scientific article

Haploinsufficiency of akt1 prolongs the lifespan of mice

scientific article

Heat shock transcription factor 1 protects cardiomyocytes from ischemia/reperfusion injury

scientific article published on 17 November 2003

Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.

scientific article published on 27 April 2018

High Frequency of Early Repolarization and Brugada-Type Electrocardiograms in Hypercalcemia.

scientific article published on 11 August 2015

Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy

scientific article

Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation.

scientific article

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

scientific article

Impact of Lipoprotein(a) as a Residual Risk Factor in Long-Term Cardiovascular Outcomes in Patients With Acute Coronary Syndrome Treated With Statins

scientific article published in 2022

In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging (MEMRI)

scientific article

Inappropriate expression of hepcidin by liver congestion contributes to anemia and relative iron deficiency.

scientific article

Inappropriate inhibition of biventricular pacing due to diaphragmatic myopotentials amplified by the selectable sensing filter

scientific article published on 01 December 2017

Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway.

scientific article published on 3 August 2017

Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.

scientific article published on 22 May 2014

Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis

scientific article

Involvement of telomerase reverse transcriptase in heterochromatin maintenance

scientific article

Leukemia inhibitory factor enhances survival of cardiomyocytes and induces regeneration of myocardium after myocardial infarction

scientific article published on 14 July 2003

Liver congestion in heart failure contributes to inappropriately increased serum hepcidin despite anemia

scientific article published on January 2015

Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia

scientific article published on 30 March 2009

Maintenance of Subcutaneous Fat Homeostasis Improves Systemic Metabolic Dysfunction in Obesity.

scientific article published in December 2015

Malfunction of cardiac resynchronization therapy due to subsequent fracture of the ring and tip conductors of a co-radial left ventricular bipolar lead

scientific article published in January 2013

Manifestation of Latent Left Ventricular Outflow Tract Obstruction in the Acute Phase of Takotsubo Cardiomyopathy.

scientific article published on December 2016

Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.

scientific article

Mechanisms of telomerase induction during vascular smooth muscle cell proliferation

scientific journal article

Metabolomic Analysis in Heart Failure

scientific article published on 8 December 2017

Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cells

scientific article published on 30 May 2013

Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway

scientific article

Pathological role of adipose tissue dysfunction in cardio-metabolic disorders.

scientific article published on 27 April 2015

Percutaneous Coronary Intervention for a Patient with Left Main Coronary Compression Syndrome.

scientific article published on 11 January 2018

Peripheral-blood or bone-marrow mononuclear cells for therapeutic angiogenesis?

article published in 2002

Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling

scientific article published on 30 June 2005

Physiological and pathological cardiac hypertrophy.

scientific article published on June 2016

Placebo-Controlled, Double-Blind Study of Empagliflozin (EMPA) and Implantable Cardioverter-Defibrillator (EMPA-ICD) in Patients with Type 2 Diabetes (T2DM): Rationale and Design

scientific article published on 23 September 2020

Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway.

scientific article published on 7 March 2017

Prognosis of Cancer Patients with Aortic Stenosis Under Optimal Cancer Therapies and Conservative Cardiac Treatments

scientific article published on 06 June 2018

Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury

scientific article published on 22 April 2010

Protective role of SIRT1 in diabetic vascular dysfunction

scientific article published on 12 March 2009

Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion.

scientific article published in April 2017

Rare Variants in ANK2 Associated With Various Inherited Arrhythmia Syndromes.

scientific article published on 3 November 2016

Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis

scientific article published on 13 October 2003

Reduced nitric oxide causes age-associated impairment of circadian rhythmicity

scientific article published on 24 January 2008

Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury

scientific article published in September 2006

Relative refractoriness of left ventricular contraction underlies human tachycardia-induced mechanical and electrical alternans

scientific article published on 11 September 2013

Remarkable thickening of right atrial wall in subjects with cardiac amyloidosis complicated with sick sinus syndrome.

scientific article published on 24 October 2006

Role of 12/15 lipoxygenase-induced inflammation in heart failure ⬇️

scientific article published on 01 November 2011

Role of Cellular Senescence in Lifestyle-Related Disease ⬇️

scientific article published on November 12, 2010

Role of Jagged1 in arterial lesions after vascular injury

scientific article

Role of adipose senescence in the regulation of insulin resistance ⬇️

scientific article published on 01 January 2011

Role of cellular aging in the regulation of insulin resistance

scientific article published on 01 May 2012

Role of mutations in L-type calcium channel genes in Brugada syndrome, early repolarization syndrome, and idiopathic ventricular fibrillation associated with right bundle branch block

scientific article published on 5 June 2013

Role of smooth muscle cell p53 in pulmonary arterial hypertension

scientific article published on 26 February 2019

Role of telomere in endothelial dysfunction in atherosclerosis

scientific article

Role of the central nervous system and adipose tissue BDNF/TrkB axes in metabolic regulation ⬇️

scientific article

SCN5A mutation associated with ventricular fibrillation, early repolarization, and concealed myocardial abnormalities

scientific article published on 17 November 2012

Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity

scientific article published on 01 October 2013

Short QT syndrome in a boy diagnosed on screening for heart disease

scientific article published on 01 October 2014

Steroid-responsive thromboangiitis obliterans

scientific article published in September 2004

The effects of pure potassium channel blocker nifekalant and sodium channel blocker mexiletine on malignant ventricular tachyarrhythmias

scientific article published on 08 September 2016

The first reported case of a transvenous left ventricular pacing lead of cardiac resynchronization therapy causing aggravation of coronary atherosclerosis.

scientific article published on 12 May 2016

The pathological role of vascular aging in cardio-metabolic disorder.

scientific article published on 16 August 2016

The role of telomerase activation in the regulation of vascular smooth muscle cell proliferation

scientific article

The role of vascular cell senescence in atherosclerosis: antisenescence as a novel therapeutic strategy for vascular aging

scientific article published on 01 April 2004

Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells

scientific article published on 04 September 2013

Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy

scientific article

Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes

scientific article published on 13 September 2016

Vascular Senescence in Cardiovascular and Metabolic Diseases.

scientific article published on 5 March 2018

Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes

scientific article

Vascular cell senescence and vascular aging

scientific article published on February 2004

Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt

scientific article published on 26 June 2008

Ventricular Rhythm and Hypotension in a Patient with Pheochromocytoma-induced Myocardial Damage and Reverse Takotsubo Cardiomyopathy.

scientific article

[Antisenescence as a novel therapeutic strategy for vascular aging].

scientific article

[Can we prevent vascular aging?]

scientific article published on 01 July 2009

[Cardiomyopathy: progress in diagnosis and treatments. Topics: IV. Selection of therapy for improvement of prognosis and QOL; 1. Up-to-date on drug therapy for chronic heart failure]

scientific article published on 01 February 2014

[Contribution of vascular cell senescence to atherogenesis]

scientific article published on 01 May 2008

[Development of anti-senescence therapy for cardiovascular disease]

scientific article published on 01 January 2009

[Endothelial cell senescence in human atherosclerosis: role of telomeres in endothelial dysfunction]

scientific article published on 01 January 2003

[Hyperinsulinemia and aging]

scientific article published on 01 June 2007

[Molecular mechanisms of atherogenesis associated with aging]

scientific article published on 01 January 2007

[Neovasculation in ischemic heart disease]

scientific article published on 01 April 2003

[Role of the renin-angiotensin system in the regulation of vascular senescence]

scientific article published on 01 April 2009

p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload.

scientific article published on 6 June 2015

p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure

scientific article published on January 2012

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

scientific article published in Nature

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