Search filters

List of works by Nicholas Schwab

Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants

scientific article

Alemtuzumab-induced immune phenotype and repertoire changes: implications for secondary autoimmunity

scientific article published on 21 February 2022

An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis

scientific article published on 31 March 2010

Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier

scientific article

Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biologica

scientific article

Assessment of immune functions and MRI disease activity in relapsing-remitting multiple sclerosis patients switching from natalizumab to fingolimod (ToFingo-Successor).

scientific article published on 23 June 2015

Author response: Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals

scientific article published on 01 September 2020

B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity

scientific article published on 26 September 2016

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus

scholarly article by Johanna Breuer et al published 22 August 2018 in Journal of Neuroinflammation

CD4+NKG2D+ T cells exhibit enhanced migratory and encephalitogenic properties in neuroinflammation.

scientific article

CD62L test at 2 years of natalizumab predicts progressive multifocal leukoencephalopathy.

scientific article

CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing.

scientific article

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

scientific article published on 18 December 2019

CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery

scientific article published on 29 January 2009

CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy

scientific article published on 11 January 2012

Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease

scientific article published on 19 June 2017

Classification of neurological diseases using multi-dimensional CSF analysis

publication published on 01 October 2021

Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice

scientific article published on 15 August 2007

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation

scientific article published in PLoS ONE

Distinct pattern of lesion distribution in multiple sclerosis is associated with different circulating T-helper and helper-like innate lymphoid cell subsets.

scientific article

Does the environment influence multiple sclerosis pathogenesis via UVB light and/or induction of vitamin D?

scientific article published on 18 May 2018

Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium

scientific article

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

scientific article published on 9 March 2010

Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data

scientific article published on 09 August 2019

FOXP3+ T regulatory cells in idiopathic inflammatory myopathies

scientific article published in August 2010

High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients

scientific article published on 05 November 2020

Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis

scientific article published on 01 November 2019

Human myoblasts modulate the function of antigen-presenting cells

article published in 2008

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor St

scientific article published on 9 July 2018

Immunological and clinical consequences of treating a patient with natalizumab

scientific article published on 9 September 2011

Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation

scientific article published on 09 May 2016

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?

scientific article published on 09 October 2019

Intercellular exchanges of membrane fragments (trogocytosis) between human muscle cells and immune cells: a potential mechanism for the modulation of muscular immune responses

scientific article published on 9 March 2009

Janus head: the dual role of HLA-G in CNS immunity

scientific article

L-selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients

scientific article published on 7 August 2013

Liver X receptor activation promotes differentiation of regulatory T cells

scientific article published on 19 September 2017

Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.

scientific article

Natalizumab-associated PML: Challenges with incidence, resulting risk, and risk stratification

scientific article

Natalizumab-associated progressive multifocal leukoencephalopathy in Germany

scientific article published on 05 April 2019

Next-Generation Neuroimmunology: New Technologies to Understand Central Nervous System Autoimmunity

scientific article published on 05 March 2020

Nitazoxanide May Modify the Course of Progressive Multifocal Leukoencephalopathy.

scientific article published on 20 November 2017

PD-1 regulates neural damage in oligodendroglia-induced inflammation

scientific article

PML risk stratification using anti-JCV antibody index and L-selectin.

scientific article published on 2 October 2015

Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals

scientific article published on 22 August 2019

Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis

scientific article published on 01 December 2010

Risks and risk management in modern multiple sclerosis immunotherapeutic treatment

scientific article published on 01 April 2019

Sex bias in MHC I-associated shaping of the adaptive immune system.

scientific article published on 12 February 2018

Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation

scientific article

Specific loss of cellular L-selectin on CD4(+) T cells is associated with progressive multifocal leukoencephalopathy development during HIV infection.

scientific article published on March 2014

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

scientific article published on 01 January 2021

T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible

scientific article published on 28 April 2009

Temporal pattern of ICAM-I mediated regulatory T cell recruitment to sites of inflammation in adoptive transfer model of multiple sclerosis

scientific article

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects

scientific article published on 01 May 2019

The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy

scientific article published on 15 October 2008

Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis.

scientific article published on 17 October 2014

Therapy with natalizumab is associated with high JCV seroconversion and rising JCV index values.

scientific article published on 27 January 2016

Trafficking of lymphocytes into the CNS.

scientific article published in July 2015

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity

scientific article published on 13 May 2014

VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells

scientific article published on 01 May 2019

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells

scientific article published on 18 August 2014

Paulina is supported by:

About Paulina

Help