List of works - Maurice S. Swanson

Aberrant Myokine Signaling in Congenital Myotonic Dystrophy

scientific article

Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy.

scientific article

Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy

scientific article

Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice

scientific article

An imidoester spin probe of membrane protein interactions: application to cytochrome c

scientific article published on 01 October 1980

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

scientific article

Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy

scientific article

Compound loss of muscleblind-like function in myotonic dystrophy

scientific article published on 08 October 2013

Constraints on the structure of (CUG)97 RNA from magic-angle-spinning solid-state NMR spectroscopy

scientific article published on 01 August 2006

Control of cleavage site selection during mRNA 3' end formation by a yeast hnRNP.

scientific article

Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

scientific article

Developmental expression of nuclear genes that encode mitochondrial proteins: insect cytochromes c.

scientific article

Developments in RNA splicing and disease

scientific article published on January 2011

Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.

scientific article published on 11 July 2017

Distal Alternative Last Exons Localize mRNAs to Neural Projections

scientific article published on 16 February 2016

Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy.

scientific article published in June 2017

Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export

scientific article

Effect of crosslinking cytochrome c oxidase.

scientific article

Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9.

scientific article

Essential role for Dicer during skeletal muscle development.

scientific article published on 25 August 2007

Fragile X tremor/ataxia syndrome: blame the messenger!

scientific article published in August 2007

Generation of a Novel SARS-CoV-2 Sub-genomic RNA Due to the R203K/G204R Variant in Nucleocapsid: Homologous Recombination has Potential to Change SARS-CoV-2 at Both Protein and RNA Level

scientific article published on 20 August 2021

Generation of neural cells from DM1 induced pluripotent stem cells as cellular model for the study of central nervous system neuropathogenesis

scientific article published on April 2013

Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells

scientific article published on June 2015

Global insights into alternative polyadenylation regulation

scientific article

Identification of NH...N hydrogen bonds by magic angle spinning solid state NMR in a double-stranded RNA associated with myotonic dystrophy

scientific article published on 18 February 2004

Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy

scientific article

Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

scientific article

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood

scientific article published on 24 April 2020

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

scientific article

MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response

scientific article

Mechanisms of RNA-mediated disease.

scientific article published on 28 October 2008

MicroRNAs in mammalian development and tumorigenesis.

scientific article published on June 2006

Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy.

scientific article

Muscleblind isoforms are functionally distinct and regulate alpha-actinin splicing.

scientific article published on 16 February 2007

Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs

scientific article published on 15 August 2007

Muscleblind-like 1 is required for normal heart valve development in vivo.

scientific article

Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain

scientific article

Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy

scientific article

Myosin light chain phosphorylation is critical for adaptation to cardiac stress

scientific article

Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

scientific article published on 20 October 2004

Nuclear RNA foci in the heart in myotonic dystrophy

scientific article published on 27 October 2005

Prediction of clustered RNA-binding protein motif sites in the mammalian genome.

scientific article published on 18 May 2013

Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice.

scientific article published on 08 May 2013

Protein-lipid interactions within purified and reconstituted cytochrome C reductase and oxidase.

scientific article published on January 1982

Purification and characterization of proteins of heterogeneous nuclear ribonucleoprotein complexes by affinity chromatography

scientific article published on 01 January 1990

RNA gain-of-function in spinocerebellar ataxia type 8.

scientific article published on 14 August 2009

RNA mis-splicing in disease

scientific article

RNA structure probing to characterize RNA-protein interactions on a low abundance pre-mRNA in living cells

scientific article published on 11 December 2020

RNA-binding protein misregulation in microsatellite expansion disorders

scientific article published on January 2014

RNA-protein interactions in unstable microsatellite diseases.

scientific article

Recent studies on hnRNP complexes

scientific article published on 01 January 1990

Rectifying RNA splicing errors in hereditary neurodegenerative disease.

scientific article

Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2

scientific article published on 01 December 2003

Role of phospholipid in the low affinity reactions between cytochrome c and cytochrome oxidase

scientific article published on 01 December 1983

SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets

scientific article published in January 2017

Silence is not always golden

scientific article published on 01 July 2011

Small molecule regulators of protein arginine methyltransferases

scientific article published on 31 March 2004

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

scientific article published on 11 April 2016

The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians

scientific article published on 27 April 2022

The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1

scientific article published on 14 September 2020

UTteR control through miRs: fine-tuning ATXN1 levels to prevent ataxia

scientific article published on 01 September 2020

Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

scientific article

Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity.

scientific article published on 12 May 2005

hnRNP complexes: composition, structure, and function

scientific article (publication date: June 1999)

List of works by Maurice S. Swanson

Aberrant Myokine Signaling in Congenital Myotonic Dystrophy

Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy.

Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy

Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice

An imidoester spin probe of membrane protein interactions: application to cytochrome c

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy

Compound loss of muscleblind-like function in myotonic dystrophy

Constraints on the structure of (CUG)97 RNA from magic-angle-spinning solid-state NMR spectroscopy

Control of cleavage site selection during mRNA 3' end formation by a yeast hnRNP.

Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

Developmental expression of nuclear genes that encode mitochondrial proteins: insect cytochromes c.

Developments in RNA splicing and disease

Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.

Distal Alternative Last Exons Localize mRNAs to Neural Projections

Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy.

Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export

Effect of crosslinking cytochrome c oxidase.

Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9.

Essential role for Dicer during skeletal muscle development.

Fragile X tremor/ataxia syndrome: blame the messenger!

Generation of a Novel SARS-CoV-2 Sub-genomic RNA Due to the R203K/G204R Variant in Nucleocapsid: Homologous Recombination has Potential to Change SARS-CoV-2 at Both Protein and RNA Level

Generation of neural cells from DM1 induced pluripotent stem cells as cellular model for the study of central nervous system neuropathogenesis

Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells

Global insights into alternative polyadenylation regulation

Identification of NH...N hydrogen bonds by magic angle spinning solid state NMR in a double-stranded RNA associated with myotonic dystrophy

Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy

Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response

Mechanisms of RNA-mediated disease.

MicroRNAs in mammalian development and tumorigenesis.

Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy.

Muscleblind isoforms are functionally distinct and regulate alpha-actinin splicing.

Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs

Muscleblind-like 1 is required for normal heart valve development in vivo.

Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain

Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy

Myosin light chain phosphorylation is critical for adaptation to cardiac stress

Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

Nuclear RNA foci in the heart in myotonic dystrophy

Prediction of clustered RNA-binding protein motif sites in the mammalian genome.

Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice.

Protein-lipid interactions within purified and reconstituted cytochrome C reductase and oxidase.

Purification and characterization of proteins of heterogeneous nuclear ribonucleoprotein complexes by affinity chromatography

RNA gain-of-function in spinocerebellar ataxia type 8.

RNA mis-splicing in disease

RNA structure probing to characterize RNA-protein interactions on a low abundance pre-mRNA in living cells

RNA-binding protein misregulation in microsatellite expansion disorders

RNA-protein interactions in unstable microsatellite diseases.

Recent studies on hnRNP complexes

Rectifying RNA splicing errors in hereditary neurodegenerative disease.

Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2

Role of phospholipid in the low affinity reactions between cytochrome c and cytochrome oxidase

SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets

Silence is not always golden

Small molecule regulators of protein arginine methyltransferases

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians

The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1

UTteR control through miRs: fine-tuning ATXN1 levels to prevent ataxia

Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity.

hnRNP complexes: composition, structure, and function