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List of works by Catherine Williamson

A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy

scientific article published on 24 December 2013

A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor

scientific article

A global call for action to include gender in research impact assessment

scientific article published on 19 July 2016

A multi-centered trial investigating gestational treatment with ursodeoxycholic acid compared to metformin to reduce effects of diabetes mellitus (GUARD): a randomized controlled trial protocol

scientific article published in 2022

A placental phenotype for intrahepatic cholestasis of pregnancy

scientific article published on 20 October 2011

A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart

scientific article published on August 2011

A series of pregnancies in women with inherited metabolic disease

scientific article published on 15 September 2011

ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy.

scientific article

ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy.

scientific article published on June 2005

Abnormal liver function tests in pregnancy

scientific article published on 25 October 2013

Absence of the genetic variant Val79Met in human chorionic gonadotropin-beta gene 5 in five European populations

scientific article

Acute and chronic Chlamydia pneumoniae infection in pregnancy complicated with preeclampsia.

scientific article published on 17 September 2010

Analysis of GAPDH as a standard for gene expression quantification in human placenta

scientific article published in September 2002

Anxiety, depression and saliva cortisol in women with a medical disorder during pregnancy

scientific article published on 26 January 2010

Approach to Hyperemesis Gravidarum

scientific article published on 9 July 2010

Assessment of adrenocortical function in women taking exogenous glucocorticoids during pregnancy

scientific article published in November 2003

Association of raised titres of antibodies to Chlamydia pneumoniae with a history of pre-eclampsia

scientific article published on March 2005

Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study

scientific article

Astroglia up-regulate transcription and secretion of 'readthrough' acetylcholinesterase following oxidative stress

scientific article published in July 2006

Authors' response: re: Intrahepatic cholestasis of pregnancy is not associated with stillbirth in an Australian maternity population.

scientific article published on 6 March 2014

Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy

scientific article published on 5 November 2014

Bile Formation and the Enterohepatic Circulation

scientific article published in September 2011

Bile acid signaling in fetal tissues: implications for intrahepatic cholestasis of pregnancy.

scientific article published on 17 June 2011

Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes

scientific article (publication date: 2010)

Bile acids and gestation.

scientific article

Canalicular ABC transporters and liver disease

scientific article published on January 2012

Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis

scientific article published on 18 April 2017

Characterisation of the nuclear receptors FXR, PXR and CAR in normal and cholestatic placenta

scientific article published on 18 May 2011

Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea.

scientific article published on 9 February 2016

Clinical outcome in a series of cases of obstetric cholestasis identified via a patient support group

scientific article published on 01 July 2004

Comparison of the arrhythmogenic effects of tauro- and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes

scientific article

Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity

scientific article published on 4 August 2011

Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy

scientific article published in April 2009

Cord liver function and bile acids in actively managed obstetric cholestasis (OC) are not abnormal

scientific article published in January 2003

Definition of the MinimalMEN1Candidate Area Based on a 5-Mb Integrated Map of Proximal 11q13

scientific article (publication date: November 1996)

Development of a disposable bile acid biosensor for use in the management of cholestasis

scientific article published in 2015

Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes

scientific article published in May 2003

Dexamethasone in the treatment of obstetric cholestasis: a case series.

scientific article published in February 2006

Diabetes and Endocrine Disease in Pregnancy

scientific article published on 5 January 2012

Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene study

scientific article

Disorders of the Liver, Biliary System and Exocrine Pancreas in Pregnancy

scientific article published on 9 July 2010

Donor transmitted mutation of the ABCB11 gene and ensuing intrahepatic cholestasis of pregnancy in a liver transplant recipient.

scientific article

Drugs in pregnancy. Gastrointestinal disease.

scientific article

Effect of maternal cholestasis on TGR5 expression in human and rat placenta at term.

scientific article published on 10 July 2013

Endocrine disease in pregnancy

scientific article published on 01 April 2013

Estradiol, farnesoid X receptor, and altered metabolism in pregnancy

scientific article published on 24 October 2014

Expression in human trophoblast and choriocarcinoma cell lines, BeWo, Jeg-3 and JAr of genes involved in the hepatobiliary-like excretory function of the placenta.

scientific article published on 19 May 2006

Functional characterization of embryonic stem cell-derived cardiomyocytes using scanning ion conductance microscopy.

scientific article published on April 2006

Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy

scientific article published on 23 May 2007

Gastrointestinal and liver disease in pregnancy

scientific article published on 01 June 2013

Gender equity programmes in academic medicine: a realist evaluation approach to Athena SWAN processes

scientific article published on 08 September 2016

Genes encoding bile acid, phospholipid and anion transporters are expressed in a human fetal cardiomyocyte culture.

scientific article

Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy

scientific article published on July 2003

Genetic factors in the pathogenesis of cholangiocarcinoma

scientific article published on 17 June 2011

Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size.

scientific article published on 12 January 2017

Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking

scientific article (publication date: May 2000)

High dose cabergoline therapy for a resistant macroprolactinoma during pregnancy.

scientific article

Identification of the Hormone Kisspeptin in Amniotic Fluid

scientific article published on 26 March 2010

Infant cortisol response after prolonged antenatal prednisolone treatment

scientific article published in December 2004

Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites

scientific article

Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid

scientific article

Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype ⬇️

scientific article published on January 8, 2013

Intrahepatic cholestasis of pregnancy

article by Catherine Williamson & Victoria Geenes published July 2014 in Obstetrics and Gynecology

Intrahepatic cholestasis of pregnancy is associated with an increased risk of gestational diabetes

scientific article published on 7 January 2014

Intrahepatic cholestasis of pregnancy: Recent advances

scientific article published on 10 February 2016

Intrahepatic cholestasis of pregnancy: an intriguing pregnancy-specific disorder

scientific article

Isolated familial hypomagnesaemia with novel neurological features: causal link or chance concurrence?

scientific article

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

scientific article published on February 2011

Liver disease in pregnancy

scientific article published in October 2011

Liver disease in pregnancy

scientific article published in March 2010

Liver disease in pregnancy

scientific article published on 15 April 2015

Liver: Links between hepatobiliary diseases in and beyond pregnancy

scientific article published on 28 May 2013

Lysophosphatidic acid is a potential mediator of cholestatic pruritus

scientific article

Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes

scientific article published on 2 December 2016

Mapping the Gene Causing Hereditary Primary Hyperparathyroidism in a Portuguese Kindred to Chromosome 1q22-q31

article

Markers of achievement for assessing and monitoring gender equity in translational research organisations: a rationale and study protocol

scientific article

Maternal cholestasis during pregnancy programs metabolic disease in offspring.

scientific article published on 24 June 2013

Maternal mortality in the UK and the need for obstetric physicians

scientific article published on 9 August 2011

Metastatic parathyroid carcinoma in the MEN2A syndrome

scientific article published on 01 December 1997

Molecular biology related to pre-eclampsia

scientific article published in April 2005

Molecular mechanistic explanation for the spectrum of cholestatic disease caused by the S320F variant of ABCB4

scientific article

Myasthenia in pregnancy: best practice guidelines from a U.K. multispecialty working group.

scientific article published on 11 June 2013

Novel circulating placental markers prokineticin-1, soluble fms-like tyrosine kinase-1, soluble endoglin and placental growth factor and association with late miscarriage.

scientific article published on 22 September 2016

Nuclear receptor-driven alterations in bile acid and lipid metabolic pathways during gestation

scientific article

Nuclear receptors, bile acids and cholesterol homeostasis series - bile acids and pregnancy

scientific article

Obstetric cholestasis

scientific article published on 19 January 2002

Obstetric cholestasis, outcome with active management: a series of 70 cases

scientific article published in March 2002

Obstetric complications due to autoantibodies

scientific article

Operative delivery rates following induction of labour for obstetric cholestasis.

scientific article published on 24 May 2011

Placental ABCA1 expression is reduced in primary antiphospholipid syndrome compared to pre-eclampsia and controls

scientific article published on 17 November 2006

Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids

scientific article

Preeclampsia with abnormal liver function tests is associated with cholestasis in a subgroup of cases

scientific article published in January 2004

Pregnancy and bile acid disorders

scientific article

Pregnancy and liver disease

scientific article published on 30 November 2015

Primum non nocere: stillbirth rate in intrahepatic cholestasis of pregnancy.

scientific article published on 27 November 2014

Progesterone metabolites as farnesoid X receptor inhibitors

scientific article published on 27 May 2015

Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

scientific article published on October 2015

Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

scientific article published in November 2001

Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function.

scientific article published on October 2010

Reduced levels of plasma kisspeptin during the antenatal booking visit are associated with increased risk of miscarriage.

scientific article

Relationship between early onset severe intrahepatic cholestasis of pregnancy and higher risk of meconium-stained fluid.

scientific article

Review of Presentation, Diagnosis and Management of Pituitary Tumours in Pregnancy

scientific article published on March 2013

Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy

scientific article published on 28 March 2015

Role of bile acid measurement in pregnancy

scientific article

Role of macrophages in bile acid-induced inflammatory response of fetal lung during maternal cholestasis.

scientific article

Saving Mothers' Lives: Reviewing maternal deaths to make motherhood safer: 2006-2008. The Eighth Report of the Confidential Enquiries into Maternal Deaths in the United Kingdom

scientific article published in March 2011

Semi quantitative expression analysis of MDR3, FIC1, BSEP, OATP-A, OATP-C,OATP-D, OATP-E and NTCP gene transcripts in 1st and 3rd trimester human placenta

scientific article

Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy

scientific article published in October 2008

Severe metabolic alkalosis in pregnancy

scientific article published on 23 July 2013

Starvation ketoacidosis in pregnancy

scientific article

The angiotensin-converting enzyme gene insertion-deletion polymorphism in a white British patient cohort with obstetric cholestasis.

scientific article published on 22 May 2009

The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis

scientific article published in April 2001

The effects of kisspeptin-54 on blood pressure in humans and plasma kisspeptin concentrations in hypertensive diseases of pregnancy

scientific article

The importance of cysteine cathepsin proteases for placental development

scientific article published on 27 January 2006

The metabolic profile of intrahepatic cholestasis of pregnancy is associated with impaired glucose tolerance, dyslipidemia, and increased fetal growth

scientific article published on 12 December 2014

The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.

scientific article

The pathophysiology of intrahepatic cholestasis of pregnancy

scientific article published on 25 January 2016

The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts.

scientific article published on 8 January 2016

The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acid

scientific article published on 08 January 2014

Treatment of Asthma

Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial.

scientific article

Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial.

scientific article

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