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List of works by Paul Dowling

2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training

article

2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines

scientific article published on 13 January 2011

7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells

scientific article published on 18 April 2014

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients

scientific article published on 25 February 2011

Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer

scientific article

Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells

scientific article

Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer

scientific article published on 19 November 2011

Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis

scientific article published on 01 May 2008

Bone disease in multiple myeloma: pathophysiology and management.

scientific article

Brain dystrophin-glycoprotein complex: persistent expression of beta-dystroglycan, impaired oligomerization of Dp71 and up-regulation of utrophins in animal models of muscular dystrophy

scientific article

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression

scientific article published on 30 April 2015

Clinical utility of C-terminal telopeptide of type 1 collagen in multiple myeloma.

scientific article published on 20 January 2016

Comparative Skeletal Muscle Proteomics Using Two-Dimensional Gel Electrophoresis.

scientific article published on 09 September 2016

Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycan

scientific article published on 01 May 2003

Conditioned media from cell lines: a complementary model to clinical specimens for the discovery of disease-specific biomarkers.

scientific article published on 13 January 2011

Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation.

scientific article

Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy.

scientific article

Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle

scientific article published in February 2002

Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy.

scientific article published on April 2004

Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents

scientific article published on December 2007

Elevated 12-hydroxyeicosatetraenoic acid (12-HETE) levels in serum of individuals with newly diagnosed Type 1 diabetes

scientific article published on 01 February 2017

Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer.

scientific article published on 23 December 2014

Identification of marker proteins of muscular dystrophy in the urine proteome from the mdx-4cv model of dystrophinopathy

scientific article published on 25 March 2020

Identification of pancreatic cancer invasion-related proteins by proteomic analysis

scientific article published on 14 February 2009

Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry.

scientific article

Label-free mass spectrometric analysis of the mdx-4cv diaphragm identifies the matricellular protein periostin as a potential factor involved in dystrophinopathy-related fibrosis

scientific article published on April 2015

Mass Spectrometry-Based Identification of Muscle-Associated and Muscle-Derived Proteomic Biomarkers of Dystrophinopathies

scientific article published on January 2014

Membrane and membrane-associated proteins involved in the aggressive phenotype displayed by highly invasive cancer cells.

scientific article published on October 2008

MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines

scientific article published on 7 October 2009

Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis

scientific article

N-Linked glycosylation profiles of therapeutic induced senescent (TIS) triple negative breast cancer cells (TNBC) and their extracellular vesicle (EV) progeny

scientific article published on 16 December 2020

New pathobiochemical insights into dystrophinopathy from the proteomics of senescent mdx mouse muscle

scientific article

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy

scientific article

Pathoproteomic profiling of the skeletal muscle matrisome in dystrophinopathy associated myofibrosis

scientific article published on 10 August 2015

Pathoproteomics of testicular tissue deficient in the GARP component VPS54: the wobbler mouse model of globozoospermia

scientific article

Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP.

scientific article

Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy.

scientific article

Proteomic analysis of isolated membrane fractions from superinvasive cancer cells

scientific article

Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin

scientific article published on 8 July 2013

Proteomic profiling of muscle fibre type shifting in neuromuscular diseases.

scientific article published on 4 July 2016

Proteomic profiling of secreted proteins from CHO cells using Surface-Enhanced Laser desorption ionization time-of-flight mass spectrometry

scientific article

Protocol for the Bottom-Up Proteomic Analysis of Mouse Spleen

scientific article published on 03 December 2020

Purification and identification of a 7.6-kDa protein in media conditioned by superinvasive cancer cells.

scientific article

Quantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome.

scientific article

RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation

scientific article

Recent advances in clinical proteomics using mass spectrometry

scientific article published on September 2010

Reduced expression of regucalcin in young and aged mdx diaphragm indicates abnormal cytosolic calcium handling in dystrophin-deficient muscle.

scientific article

Subproteomics analysis of Ca+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle

scientific article published in October 2004

The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro.

scientific article published on 7 May 2015

The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines

scientific article published on July 2012

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