List of works - Sarah Howie

A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues.

scientific article published in February 2004

Acute Liver Injury Is Independent of B Cells or Immunoglobulin M.

scientific article published on 25 September 2015

Adjuvanticity and toxicity of cobalt oxide nanoparticles as an alternative vaccine adjuvant

scientific article

Cerebrospinal fluid interleukin-8 levels are higher in people with hip fracture with perioperative delirium than in controls

scientific article

Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1β in delirium after hip fracture

scientific article

Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice

scientific article published on 10 January 2020

Chlamydia trachomatis infection during pregnancy: known unknowns

scientific article published on July 2011

Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release.

scientific article

Combination peptide immunotherapy based on T-cell epitope mapping reduces allergen-specific IgE and eosinophilia in allergic airway inflammation

scientific article published on March 2013

Commercially available recombinant sonic hedgehog up-regulates Ptc and modulates the cytokine and chemokine expression of human macrophages: an effect mediated by endotoxin contamination?

scientific article

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6.

scientific article

Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression.

scientific article published on 14 September 2010

Effector and central memory T helper 2 cells respond differently to peptide immunotherapy

scientific article published on 10 February 2014

Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes

scientific article

FITC-induced murine pulmonary inflammation: CC10 up-regulation and concurrent Shh expression

scientific article

Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells.

scientific article

Go girls! Efficient female innate immunity ⬇️

scientific article published on November 24, 2011

High-fat feeding redirects cytokine responses and decreases allergic airway eosinophilia

scientific article published on 22 January 2009

Histologic assessment of tumor-associated CD45(+) cell numbers is an independent predictor of prognosis in small cell lung cancer

scientific article

Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4+CD25+Foxp3+ regulatory T cells

scientific article

Human neutrophil elastase inhibitors in innate and adaptive immunity.

scientific article

IL-10 permits transient activation of dendritic cells to tolerize T cells and protect from central nervous system autoimmune disease

scientific article published on 28 July 2007

Immunity and vaccines against sexually transmitted Chlamydia trachomatis infection

scientific article published on February 2011

Inclusion counter: a public domain image analysis system for measurement of Chlamydiaceae growth in vitro

scientific article

Increased cycling cell numbers and stem cell associated proteins as potential biomarkers for high grade human papillomavirus+ve pre-neoplastic cervical disease

scientific article

Induction of inflammatory host immune responses by organisms belonging to the genera Chlamydia/Chlamydophila.

scientific article published on August 2004

Inflammatory Lung Secretions Inhibit Dendritic Cell Maturation and Function via Neutrophil Elastase

article

Inhibition of TCR-mediated shedding of L-selectin (CD62L) on human and mouse CD4+ T cells by metalloproteinase inhibition: analysis of the regulation of Th1/Th2 function

scientific article published in October 2002

Interferon gamma in keratinocytes in psoriasis

scientific article published on 01 May 2003

Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF

scientific article published on 11 April 2019

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

scientific article

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

scientific article published in September 2011

Macrophage chemotaxis to apoptotic Burkitt's lymphoma cells in vitro: role of CD14 and CD36

scientific article published in August 2004

NiO and Co3O4 nanoparticles induce lung DTH-like responses and alveolar lipoproteinosis

scientific article published on 4 August 2011

Notch1 co-localizes with CD4 on activated T cells and Notch signaling is required for IL-10 production

scientific article

Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease

scientific article published on 29 October 2010

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes.

scientific article

Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

scientific article published on March 2016

Resolution of Der p1-induced allergic airway inflammation is dependent on CD4+CD25+Foxp3+ regulatory cells

scientific article published in November 2007

Small cell lung cancer tumour cells induce regulatory T lymphocytes, and patient survival correlates negatively with FOXP3+ cells in tumour infiltrate

scientific article published on 14 May 2012

Sonic Hedgehog Signaling Modulates Activation of and Cytokine Production by Human Peripheral CD4+ T Cells

scientific article published on 15 November 2002

Sonic hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes

scientific article (publication date: 15 August 2002)

TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells

scientific article

The Notch and Sonic hedgehog signalling pathways in immunity.

scientific article published in July 2004

The antimicrobial/elastase inhibitor elafin regulates lung dendritic cells and adaptive immunity

scientific article published on 19 January 2006

The hedgehog signalling pathway in the gastrointestinal tract: implications for development, homeostasis, and disease

scientific article

The role of infection in miscarriage

scientific article

The role of macrophages in healing the wounded lung

scientific article published on 07 July 2012

The role of vascular endothelial growth factor in the kidney in health and disease

scientific article published in 2004

The use of hyperosmotic saline for chondroprotection: implications for orthopaedic surgery and cartilage repair

scientific article published on 11 December 2014

Therapeutic molecular targets in human chondrosarcoma

scientific article published on October 2010

“Dirty little secrets”—Endotoxin contamination of recombinant proteins

scientific article published in July 2006

List of works by Sarah Howie

A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues.

Acute Liver Injury Is Independent of B Cells or Immunoglobulin M.

Adjuvanticity and toxicity of cobalt oxide nanoparticles as an alternative vaccine adjuvant

Cerebrospinal fluid interleukin-8 levels are higher in people with hip fracture with perioperative delirium than in controls

Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1β in delirium after hip fracture

Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice

Chlamydia trachomatis infection during pregnancy: known unknowns

Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release.

Combination peptide immunotherapy based on T-cell epitope mapping reduces allergen-specific IgE and eosinophilia in allergic airway inflammation

Commercially available recombinant sonic hedgehog up-regulates Ptc and modulates the cytokine and chemokine expression of human macrophages: an effect mediated by endotoxin contamination?

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6.

Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression.

Effector and central memory T helper 2 cells respond differently to peptide immunotherapy

Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes

FITC-induced murine pulmonary inflammation: CC10 up-regulation and concurrent Shh expression

Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells.

Go girls! Efficient female innate immunity ⬇️

High-fat feeding redirects cytokine responses and decreases allergic airway eosinophilia

Histologic assessment of tumor-associated CD45(+) cell numbers is an independent predictor of prognosis in small cell lung cancer

Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4+CD25+Foxp3+ regulatory T cells

Human neutrophil elastase inhibitors in innate and adaptive immunity.

IL-10 permits transient activation of dendritic cells to tolerize T cells and protect from central nervous system autoimmune disease

Immunity and vaccines against sexually transmitted Chlamydia trachomatis infection

Inclusion counter: a public domain image analysis system for measurement of Chlamydiaceae growth in vitro

Increased cycling cell numbers and stem cell associated proteins as potential biomarkers for high grade human papillomavirus+ve pre-neoplastic cervical disease

Induction of inflammatory host immune responses by organisms belonging to the genera Chlamydia/Chlamydophila.

Inflammatory Lung Secretions Inhibit Dendritic Cell Maturation and Function via Neutrophil Elastase

Inhibition of TCR-mediated shedding of L-selectin (CD62L) on human and mouse CD4+ T cells by metalloproteinase inhibition: analysis of the regulation of Th1/Th2 function

Interferon gamma in keratinocytes in psoriasis

Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

Macrophage chemotaxis to apoptotic Burkitt's lymphoma cells in vitro: role of CD14 and CD36

NiO and Co3O4 nanoparticles induce lung DTH-like responses and alveolar lipoproteinosis

Notch1 co-localizes with CD4 on activated T cells and Notch signaling is required for IL-10 production

Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes.

Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

Resolution of Der p1-induced allergic airway inflammation is dependent on CD4+CD25+Foxp3+ regulatory cells

Small cell lung cancer tumour cells induce regulatory T lymphocytes, and patient survival correlates negatively with FOXP3+ cells in tumour infiltrate

Sonic Hedgehog Signaling Modulates Activation of and Cytokine Production by Human Peripheral CD4+ T Cells

Sonic hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes

TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells

The Notch and Sonic hedgehog signalling pathways in immunity.

The antimicrobial/elastase inhibitor elafin regulates lung dendritic cells and adaptive immunity

The hedgehog signalling pathway in the gastrointestinal tract: implications for development, homeostasis, and disease

The role of infection in miscarriage

The role of macrophages in healing the wounded lung

The role of vascular endothelial growth factor in the kidney in health and disease

The use of hyperosmotic saline for chondroprotection: implications for orthopaedic surgery and cartilage repair

Therapeutic molecular targets in human chondrosarcoma

“Dirty little secrets”—Endotoxin contamination of recombinant proteins