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List of works by Michelle Craig Barton

A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene

scientific journal article

An essential role for UTX in resolution and activation of bivalent promoters

scientific article published on 13 January 2016

An optional laboratory in molecular techniques as an aid in the teaching of medical biochemistry

Analysis of epigenetic alterations to chromatin during development

scientific article published on August 2009

Bromodomain Histone Readers and Cancer

scientific article published on 24 November 2016

Cancer: Acidic shield puts a chink in p53's armour

scientific article published on 14 September 2016

Cascades of transcription regulation during liver regeneration

scientific article

Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis

scientific article published on 5 February 2007

Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression

scientific journal article

Coordinate estrogen induction of vitellogenin and a small serum protein mRNA in Xenopus laevis liver

scientific article published on 01 February 1985

Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo

scientific article published on 05 August 2020

Deregulation of cyclin E meets dysfunction in p53: closing the escape hatch on breast cancer

scientific article published on December 2006

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

scientific article

Direct activation of forkhead box O3 by tumor suppressors p53 and p73 is disrupted during liver regeneration in mice

scientific article published on September 2010

Dual Roles of RNF2 in Melanoma Progression

scientific article

Editorial

Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription

scientific article published on 2 October 2005

Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells

scientific article

Functional analysis of chromatin assembled in synthetic nuclei

scientific article published in February 1999

Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2 ⬇️

scientific article

Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells

scientific article published on 27 September 2013

HDAC3 at the Fulcrum of an Epithelial-Mesenchymal Balance ⬇️

scientific article published on September 2, 2011

Hepatitis B viral transactivator HBx alleviates p53-mediated repression of alpha-fetoprotein gene expression

scientific article published in Journal of Biological Chemistry

Hepatocyte nuclear factor 3 relieves chromatin-mediated repression of the alpha-fetoprotein gene

scientific article published on August 1999

Hierarchies of transcriptional regulation during liver regeneration

scientific article published on January 2010

Hierarchy of a regenerative cell cycle: cyclin E1 multitasks

scientific article published on 13 December 2013

Histone H3 lysine 23 acetylation is associated with oncogene TRIM24 expression and a poor prognosis in breast cancer

scientific article published on 16 September 2016

Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly

scientific article (publication date: 21 February 2003)

Hypoxia induces a novel signature of chromatin modifications and global repression of transcription

scientific article published on 16 January 2008

Hypoxia-induced and stress-specific changes in chromatin structure and function

scientific article published on 21 January 2007

In vitro reconstitution of nuclei for replication and transcription

scientific article published in January 1999

Influences along the path to maturity: regulation of cellular levels of RNA.

scientific article published on August 2006

Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

scientific article

Integrative genomics: liver regeneration and hepatocellular carcinoma

scientific article published on July 2012

KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells

scientific article published on 18 May 2020

Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets

scientific article published on June 2005

LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.

scientific article published on December 2016

Making sense of ubiquitin ligases that regulate p53 ⬇️

scientific article published on October 1, 2010

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

scientific article published on 10 September 2021

Many forkheads in the road to regulation. Symposium on forkhead transcription factor networks in development, signalling and disease

scientific article (publication date: August 2008)

MicroRNA Regulates Hepatocytic Differentiation of Progenitor Cells by Targeting YAP1.

scientific article published on 5 January 2016

Microarray analysis of hepatic-regulated gene expression: Specific applications and nonspecific problems

article

Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells

scientific article published on 6 October 2015

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

scientific article

Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development

scientific article

Nonpeptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity

scientific article published on 5 September 2013

Oncogenic <i>KRAS</i> Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis

publication published on 10 April 2021

Outside the p53 RING: Transcription Regulation by Chromatin-Bound MDM2.

scientific article published in June 2016

Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma

scientific article

Rapid monoisotopic cisplatin based barcoding for multiplexed mass cytometry

scientific article published on 19 June 2017

Regulated gene expression in reconstituted chromatin and synthetic nuclei

scientific article published in January 1996

Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation

scientific article published on 07 October 2013

Regulation of gene expression in human cancers by TRIM24.

scientific article

Regulation of p53: TRIM24 enters the RING.

scientific article

Repair of psoralen interstrand cross-links in Xenopus laevis egg extracts is highly mutagenic

scientific article published in October 2005

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

scientific article

S-Phase progression mediates activation of a silenced gene in synthetic nuclei

scientific article

Sample Preparation for Mass Cytometry Analysis

scientific article published on 29 April 2017

Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor

scientific article published on 10 June 2015

Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression

scientific article

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.

scientific article

TRIM-ing Ligand Dependence in Castration-Resistant Prostate Cancer

scientific article published in June 2016

TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage

scientific article

TRIM24 links a non-canonical histone signature to breast cancer

scientific article

TRIM24 links glucose metabolism with transformation of human mammary epithelial cells

scientific article

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

scientific article published on 9 January 2017

The APC Tumor Suppressor Promotes Transcription-Independent Apoptosis In vitro

scientific article published on 01 February 2005

The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus

scientific article

The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205.

scientific article published on 13 December 2012

The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells

scientific article published on 13 December 2012

Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene

scientific article

Trim24 targets endogenous p53 for degradation

scientific article

Ubp8 and SAGA regulate Snf1 AMP kinase activity.

scientific article

Uncoupling of S-Phase and Mitosis by Recombinant Cytotoxic Necrotizing Factor 2 (CNF2) ⬇️

scientific article published on July 10, 1997

Unmet Expectations: miR-34 Plays No Role in p53-Mediated Tumor Suppression In Vivo ⬇️

scientific article published on July 26, 2012

Verteporfin inhibits PD-L1 through autophagy and the STAT1-IRF1-TRIM28 signaling axis, exerting antitumor efficacy

scientific article published on 07 April 2020

Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases

scientific article published on 20 October 2009

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer

scientific article published on 12 November 2019

ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

scientific article

Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver

scientific journal article

p53

p53

p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity

scientific article published on 12 June 2017

p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver

scientific article published on 15 February 2013

p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells

scientific article

p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression

scientific article published on 25 September 2001

p53-Mediated regulation of hepatic lipid metabolism: Forging links between metabolism, atherogenesis, and cancer

scientific article published on 31 October 2011

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.

scientific article

p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo

scientific article published on 23 June 2008

p53: emerging roles in stem cells, development and beyond

scientific article published on 13 April 2018

von Hippel-Lindau Protein Induces Hypoxia-regulated Arrest of Tyrosine Hydroxylase Transcript Elongation in Pheochromocytoma Cells

scientific article published in Journal of Biological Chemistry

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