Search filters

List of works by Gyanu Lamichhane

A comparative modeling and molecular docking study on Mycobacterium tuberculosis targets involved in peptidoglycan biosynthesis.

scientific article

A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis

scientific article

A screen for non-coding RNA in Mycobacterium tuberculosis reveals a cAMP-responsive RNA that is expressed during infection

scientific article

Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice

scientific article published on 23 April 2007

Allosteric cooperation in β-lactam binding to a non-classical transpeptidase

scientific article published on 27 April 2022

An evolved oxazolidinone with selective potency against Mycobacterium tuberculosis and gram positive bacteria

scientific article published on 9 June 2016

Bacterial thymidine kinase as a non-invasive imaging reporter for Mycobacterium tuberculosis in live animals ⬇️

scientific article

Carbapenems against Mycobacterium tuberculosis: a review of the evidence

scientific article

Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus.

scientific article

Combining cheminformatics methods and pathway analysis to identify molecules with whole-cell activity against Mycobacterium tuberculosis

scientific article (publication date: August 2012)

Copper resistance is essential for virulence of Mycobacterium tuberculosis

scientific article

Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase

scientific journal article

Defining the 'survivasome' of Mycobacterium tuberculosis

scientific article published on 01 March 2007

Definition and annotation of (myco)bacterial non-coding RNA.

scientific article published on 4 January 2013

Deletion of a Mycobacterium tuberculosis proteasomal ATPase homologue gene produces a slow-growing strain that persists in host tissues

scientific article published on 02 October 2006

Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs

scientific article

Development of a penem antibiotic against Mycobacteroides abscessus

scientific article published on 07 December 2020

Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice

scientific article

Drug resistance mechanisms and novel drug targets for tuberculosis therapy

scientific article published on 11 October 2016

Essential metabolites of Mycobacterium tuberculosis and their mimics

scientific article

Genetic requirements for the survival of tubercle bacilli in primates

scientific article

Have we realized the full potential of β-lactams for treating drug-resistant TB?

scientific article published on 22 June 2018

Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment

scientific article (publication date: 2015)

In Vitro Activity of the New β-Lactamase Inhibitors Relebactam and Vaborbactam in Combination with β-Lactams against Mycobacterium abscessus Complex Clinical Isolates

scientific article published on 26 February 2019

Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase

scientific article published on 12 December 2016

Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.

scientific article

Murine model to study the invasion and survival of Mycobacterium tuberculosis in the central nervous system

scientific journal article

Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis

scientific article published on 9 January 2017

Mycobacterium Tuberculosis Response to Stress from Reactive Oxygen and Nitrogen Species ⬇️

scientific article published on August 27, 2011

Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins

scientific article published on 31 July 2017

Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis.

scientific article

Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis

scientific article published on 15 January 2009

Non-classical transpeptidases yield insight into new antibacterials

scientific article

Novel targets in M. tuberculosis: search for new drugs ⬇️

scientific article published on November 9, 2010

Protective efficacy of BCG overexpressing an L,D-transpeptidase against M. tuberculosis infection

scientific article

Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.

scientific article published on 24 April 2017

REMap: Operon map of M. tuberculosis based on RNA sequence data

scientific article

Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis.

scientific article

Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models.

scientific article published on 22 December 2008

Select β-Lactam Combinations Exhibit Synergy against Mycobacterium abscessus In Vitro

scientific article published on 27 March 2019

Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.

scientific article

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.

scientific article

Synergistic Efficacy of β-Lactam Combinations against Mycobacterium abscessus Pulmonary Infection in Mice

scientific article published on 25 July 2019

Systems biology-based identification of Mycobacterium tuberculosis persistence genes in mouse lungs

scientific article

Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2

scientific article

Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2.

scientific article published on 12 March 2015

The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin.

scientific article published on 21 March 2010

The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models

scientific article

β-lactam combinations that exhibit synergy against <i>Mycobacteroides abscessus</i> clinical isolates

scientific article published on 23 December 2020

Paulina is supported by:

About Paulina

Help