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List of works by Nicolas Fasel

A functional BH3 domain in an aquaporin from Leishmania infantum.

scientific article published on 04 July 2016

A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major

scientific article

A recombinant rubella virus E1 glycoprotein as a rubella vaccine candidate

scientific article published in December 2004

Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis

scientific article published on 19 June 2019

An essential role for the Leishmania major metacaspase in cell cycle progression.

scientific article

Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.

scientific article published on 17 January 2017

Apoptotic markers in protozoan parasites

scientific article

Backseat drivers: the hidden influence of microbial viruses on disease

scientific article published on 11 June 2012

Caspase-mediated cleavage of raptor participates in the inactivation of mTORC1 during cell death

scientific article published on 18 April 2016

Cathepsin B-like and cell death in the unicellular human pathogen Leishmania

scientific article published on 2 September 2010

Cell death in Leishmania induced by stress and differentiation: programmed cell death or necrosis?

scientific article published in October 2002

Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases

scientific article published on 01 March 2020

Comparative protein profiling identifies elongation factor-1beta and tryparedoxin peroxidase as factors associated with metastasis in Leishmania guyanensis.

scientific article

Cross-presenting dendritic cells are required for control ofLeishmania majorinfection

scientific article published on 25 March 2014

Development of a semi-automated image-based high-throughput drug screening system

scientific article published on January 2018

Dictyostelium discoideum as an expression host for the circumsporozoite protein of Plasmodium falciparum

scientific article published in February 1992

Embryonic development of NMRI mice: relationship between the weight, age and ossification of embryos

scientific article

Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis.

scientific article

Enhanced sensitivity detection of protein immobilization by fluorescent interference on oxidized silicon

scientific article published in December 2003

Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid.

scientific article

Expression and one-step purification of Plasmodium proteins in dictyostelium.

scientific article published in December 2000

Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis

scientific article published in March 2003

Genomic organization and gene expression in a chromosomal region of Leishmania major.

scientific article published on April 2004

Guidelines and recommendations on yeast cell death nomenclature.

scientific article published in January 2018

Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector

scientific article published on February 1992

Histone H1 expression varies during the Leishmania major life cycle.

scientific article

Histone H1 regulates chromatin condensation in Leishmania parasites

scientific article published on 4 January 2007

How to master the host immune system? Leishmania parasites have the solutions!

scientific article published on 23 December 2017

Humoral and cellular immune responses against Type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population

scientific article published in January 2004

Identification of Leishmania major cysteine proteinases as targets of the immune response in humans

scientific article published in March 2001

Identification of a histone H1-like gene expressed in Leishmania major

scientific article published in December 1993

Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis.

scientific article published on 04 June 2007

Implication of different domains of the Leishmania major metacaspase in cell death and autophagy

scientific article

Importance of polyphosphate in the Leishmania life cycle

scientific article published on 22 June 2018

Induction of macrophage nitric oxide production by interferon-gamma and tumor necrosis factor-alpha is enhanced by interleukin-10

scientific article published on 01 August 1993

Isolation from mouse fibroblasts of a cDNA encoding a new form of the fibroblast growth factor receptor (flg).

scientific article

Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis

scientific article published on February 2011

Leishmania RNA virus: when the host pays the toll

scientific article published on 12 July 2012

Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response

scientific article

Leishmania amazonensis downregulates macrophage iNOS expression via Histone Deacetylase 1 (HDAC1): A novel parasite evasion mechanism.

scientific article published on 12 April 2018

Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β.

scientific article

Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity

article by Iveth J. González et al published February 2007 in International Journal for Parasitology

Leishmania major: histone H1 gene expression from the sw3 locus.

scientific article

Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A.

scientific article

Long synthetic peptides as biologically active proteins: the example of the chemokines

scientific article published on 01 September 2001

Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter.

scientific article published in December 2017

Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence

scientific article

Mapping the proteome of Leishmania Viannia parasites using two-dimensional polyacrylamide gel electrophoresis and associated technologies.

scientific article published in June 2003

Membrane mu poly(A) signal and 3' flanking sequences function as a transcription terminator for immunoglobulin-encoding genes

scientific article published on December 1992

Minimal membrane and secreted mu poly(A) signals specify developmentally-regulated immunoglobulin heavy chain mRNA ratios without RNA splicing

scientific article published on May 1994

Muco-cutaneous leishmaniasis in the New World: the ultimate subversion.

scientific article

Mucocutaneous leishmaniasis and an undesired passenger

scientific article published on 30 November 2011

MyD88 and TLR9 dependent immune responses mediate resistance to Leishmania guyanensis infections, irrespective of Leishmania RNA virus burden

scientific article

Native-like, long synthetic peptides as components of sub-unit vaccines: practical and theoretical considerations for their use in humans.

scientific article

Nucleotide sequence of the 5' noncoding region and part of the gag gene of mouse mammary tumor virus; identification of the 5' splicing site for subgenomic mRNAs.

scientific article published on October 1983

Plasmodium falciparum Metacaspase PfMCA-1 Triggers a z-VAD-fmk Inhibitable Protease to Promote Cell Death ⬇️

scientific article published on August 17, 2011

Presence of Leishmania RNA Virus 1 in Leishmania guyanensis Increases the Risk of First-Line Treatment Failure and Symptomatic Relapse

scientific article published on 29 June 2015

Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major

scientific article published on 9 November 2010

Production and use of monoclonal IgA antibodies complexed with recombinant secretory component for passive mucosal protection

scientific article published on 01 January 1991

Protection against cutaneous leishmaniasis in outbred vervet monkeys using a recombinant histone H1 antigen

scientific article published in October 2003

Purification of recombinant proteins by chemical removal of the affinity tag

scientific article published on 01 August 1998

Raptor hunted by caspases

scientific article published on 2 June 2016

Resistance to oxidative stress is associated with metastasis in mucocutaneous leishmaniasis

scientific article published on 8 September 2006

Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 mRNA translation.

scientific article published on 6 February 2018

Role of Toll-like receptor 9 signaling in experimental Leishmania braziliensis infection

scientific article published on 25 February 2013

Sense and antisense transcripts in the histone H1 (HIS-1) locus of Leishmania major

scientific article published in August 2003

Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus

scientific article published on February 2016

Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein

scientific article published in December 1995

Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis

scientific article published on 15 September 2017

T cell receptor beta chain gene rearrangements and V beta gene usage in horse cytochrome c-specific T cell hybridomas

scientific article published in May 1987

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection

scientific article published on 27 December 2018

Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death.

scientific article

The criminal association of Leishmania parasites and viruses

scientific article published on 07 August 2018

The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.

scientific article

The protective capacities of histone H1 against experimental murine cutaneous leishmaniasis

scientific article published on 01 December 1999

The therapeutic potential of immune cross-talk in leishmaniasis

scientific article published on February 2013

Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response.

scientific article published on 18 October 2016

Translocation of the yeast dolichol-phosphate-mannose synthase into microsomal membranes

scientific article published on 01 February 1991

Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo

scientific article

Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis.

scientific article published on 24 April 2017

Type I signal peptidase from Leishmania is a target of the immune response in human cutaneous and visceral leishmaniasis

scientific article published on May 2004

Unveiling the Role of the Integrated Endoplasmic Reticulum Stress Response in Leishmania Infection - Future Perspectives.

scientific article published on 22 July 2016

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania.

scientific article published on 28 December 2017

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