List of works - Thomas J. Smith

A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis

scientific article

Aggregation of TMV CP plays a role in CP functions and in coat-protein-mediated resistance

scientific article

An antibody to the putative aphid recognition site on cucumber mosaic virus recognizes pentons but not hexons

scientific article published on December 2002

Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization

scientific article

Antiviral agent blocks breathing of the common cold virus.

scientific article

Atomic Structure of Salutaridine Reductase from the Opium Poppy (Papaver somniferum)

scientific article

Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity

scholarly article

Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm

scientific article published on 24 June 2009

Crystallization and Characterization of Bovine Liver Glutamate Dehydrogenase

scientific article published on 01 October 1997

Crystallization and preliminary X-ray diffraction analysis of salutaridine reductase from the opium poppy Papaver somniferum

scientific article

Developing a new interdisciplinary lab course for undergraduate and graduate students: Plant cells and proteins

article

Differential antifungal and calcium channel-blocking activity among structurally related plant defensins

scientific article

Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation

scientific article published in November 2004

Fungal virus capsids, cytoplasmic compartments for the replication of double-stranded RNA, formed as icosahedral shells of asymmetric Gag dimers

scientific article published on December 1994

Green Tea Polyphenols Control Dysregulated Glutamate Dehydrogenase in Transgenic Mice by Hijacking the ADP Activation Site

scientific article

Green tea polyphenols in drug discovery: a success or failure? ⬇️

scientific article published on June 1, 2011

Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase

scientific article published on 13 February 2006

High throughput screening reveals several new classes of glutamate dehydrogenase inhibitors

scientific article published on 29 November 2007

High-Resolution X-Ray Structure and Functional Analysis of the Murine Norovirus 1 Capsid Protein Protruding Domain

scientific article

High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains

scientific article

Human rhinovirus capsid dynamics is controlled by canyon flexibility

scientific article published in September 2003

Identification of viral mutants by mass spectrometry.

scientific article

Induction of particle polymorphism by cucumber necrosis virus coat protein mutants in vivo

scientific article published on 21 November 2007

KP4 fungal toxin inhibits growth in Ustilago maydis by blocking calcium uptake.

scientific article

MOLView: A program for analyzing and displaying atomic structures on the Macintosh personal computer

scientific article published on 01 April 1995

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase

scientific article

Multidomain Carbohydrate-binding Proteins Involved in Bacteroides thetaiotaomicron Starch Metabolism ⬇️

scientific article published on August 21, 2012

Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon.

scientific article

Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS

scientific article

Plant defensins and virally encoded fungal toxin KP4 inhibit plant root growth

scientific article published on 12 September 2007

Pocket factors are unlikely to play a major role in the life cycle of human rhinovirus

scientific article

Possible regulatory role for the histidine-rich loop in the zinc transport protein, ZnuA

scientific article

Purification and crystallization of intact human rhinovirus complexed with a neutralizing fab

scientific article published on 01 December 1992

Putative receptor binding sites on alphaviruses as visualized by cryoelectron microscopy

scientific article

Starch Catabolism by a Prominent Human Gut Symbiont Is Directed by the Recognition of Amylose Helices

scientific article

Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle

scientific article

Structural determinants of metal specificity in the zinc transport protein ZnuA from synechocystis 6803

scientific article

Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation

scientific article (publication date: April 2003)

Structural studies on antibody recognition and neutralization of viruses

scientific article published on August 2011

Structural studies on antibody-virus complexes

scientific article

Structure of Cowpea mottle virus: a consensus in the genus Carmovirus

scientific article published in April 2004

Structure of a SusD Homologue, BT1043, Involved in Mucin O -Glycan Utilization in a Prominent Human Gut Symbiont † , ‡

scientific article

Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles

scientific article

Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum

scientific article

Structures of T=1 and T=3 particles of cucumber necrosis virus: evidence of internal scaffolding

scientific article published on 28 September 2006

Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation

scientific article

SusG: a unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules

scientific article

The atomic structure of the virally encoded antifungal protein, KP6

scientific article

The characterization and crystallization of a virally encoded Ustilago maydis KP4 toxin

scientific article published on 01 November 1994

The structure and allosteric regulation of glutamate dehydrogenase

scientific article

The structure and allosteric regulation of mammalian glutamate dehydrogenase

scientific article published on 4 November 2011

The structure of a cyanobacterial bicarbonate transport protein, CmpA.

scientific article published on 22 November 2006

The structure of apo human glutamate dehydrogenase details subunit communication and allostery

scientific article

The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery

scientific article

The structure of cucumber mosaic virus and comparison to cowpea chlorotic mottle virus

scientific article published in August 2000

The structure of the iron-binding protein, FutA1, from Synechocystis 6803

scientific article

The virally encoded fungal toxin KP4 specifically blocks L-type voltage-gated calcium channels

scientific article published in April 2002

Transgenic maize plants expressing the Totivirus antifungal protein, KP4, are highly resistant to corn smut

scientific article

Untangling the glutamate dehydrogenase allosteric nightmare

scientific article published on 24 September 2008

VP4 protein from human rhinovirus 14 is released by pressure and locked in the capsid by the antiviral compound WIN.

scientific article published on 11 November 2006

Viral capsid mobility: a dynamic conduit for inactivation.

scholarly article

List of works by Thomas J. Smith

A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis

Aggregation of TMV CP plays a role in CP functions and in coat-protein-mediated resistance

An antibody to the putative aphid recognition site on cucumber mosaic virus recognizes pentons but not hexons

Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization

Antiviral agent blocks breathing of the common cold virus.

Atomic Structure of Salutaridine Reductase from the Opium Poppy (Papaver somniferum)

Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity

Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm

Crystallization and Characterization of Bovine Liver Glutamate Dehydrogenase

Crystallization and preliminary X-ray diffraction analysis of salutaridine reductase from the opium poppy Papaver somniferum

Developing a new interdisciplinary lab course for undergraduate and graduate students: Plant cells and proteins

Differential antifungal and calcium channel-blocking activity among structurally related plant defensins

Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation

Fungal virus capsids, cytoplasmic compartments for the replication of double-stranded RNA, formed as icosahedral shells of asymmetric Gag dimers

Green Tea Polyphenols Control Dysregulated Glutamate Dehydrogenase in Transgenic Mice by Hijacking the ADP Activation Site

Green tea polyphenols in drug discovery: a success or failure? ⬇️

Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase

High throughput screening reveals several new classes of glutamate dehydrogenase inhibitors

High-Resolution X-Ray Structure and Functional Analysis of the Murine Norovirus 1 Capsid Protein Protruding Domain

High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains

Human rhinovirus capsid dynamics is controlled by canyon flexibility

Identification of viral mutants by mass spectrometry.

Induction of particle polymorphism by cucumber necrosis virus coat protein mutants in vivo

KP4 fungal toxin inhibits growth in Ustilago maydis by blocking calcium uptake.

MOLView: A program for analyzing and displaying atomic structures on the Macintosh personal computer

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase

Multidomain Carbohydrate-binding Proteins Involved in Bacteroides thetaiotaomicron Starch Metabolism ⬇️

Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon.

Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS

Plant defensins and virally encoded fungal toxin KP4 inhibit plant root growth

Pocket factors are unlikely to play a major role in the life cycle of human rhinovirus

Possible regulatory role for the histidine-rich loop in the zinc transport protein, ZnuA

Purification and crystallization of intact human rhinovirus complexed with a neutralizing fab

Putative receptor binding sites on alphaviruses as visualized by cryoelectron microscopy

Starch Catabolism by a Prominent Human Gut Symbiont Is Directed by the Recognition of Amylose Helices

Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle

Structural determinants of metal specificity in the zinc transport protein ZnuA from synechocystis 6803

Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation

Structural studies on antibody recognition and neutralization of viruses

Structural studies on antibody-virus complexes

Structure of Cowpea mottle virus: a consensus in the genus Carmovirus

Structure of a SusD Homologue, BT1043, Involved in Mucin O -Glycan Utilization in a Prominent Human Gut Symbiont † , ‡

Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles

Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum

Structures of T=1 and T=3 particles of cucumber necrosis virus: evidence of internal scaffolding

Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation

SusG: a unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules

The atomic structure of the virally encoded antifungal protein, KP6

The characterization and crystallization of a virally encoded Ustilago maydis KP4 toxin

The structure and allosteric regulation of glutamate dehydrogenase

The structure and allosteric regulation of mammalian glutamate dehydrogenase

The structure of a cyanobacterial bicarbonate transport protein, CmpA.

The structure of apo human glutamate dehydrogenase details subunit communication and allostery

The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery

The structure of cucumber mosaic virus and comparison to cowpea chlorotic mottle virus

The structure of the iron-binding protein, FutA1, from Synechocystis 6803

The virally encoded fungal toxin KP4 specifically blocks L-type voltage-gated calcium channels

Transgenic maize plants expressing the Totivirus antifungal protein, KP4, are highly resistant to corn smut

Untangling the glutamate dehydrogenase allosteric nightmare

VP4 protein from human rhinovirus 14 is released by pressure and locked in the capsid by the antiviral compound WIN.

Viral capsid mobility: a dynamic conduit for inactivation.