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List of works by Julià Blanco

69-kDa and 100-kDa isoforms of interferon-induced (2'-5')oligoadenylate synthetase exhibit differential catalytic parameters.

scientific article

A baseline metabolomic signature is associated with immunological CD4+ T-cell recovery after 36 months of ART in HIV-infected patients.

scientific article published on 26 December 2017

A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.

scientific article published on 24 May 2011

A cytokine pattern that differentiates pre- from post- seroconversion phases of primary HIV infection

scientific article

Adenine nucleotides and adenosine metabolism in pig kidney proximal tubule membranes

scientific article published on 01 October 1993

Adenosine deaminase enhances the immunogenicity of human dendritic cells from healthy and HIV-infected individuals

scientific article

Adenosine metabolism in kidney slices under normoxic conditions.

scientific article

Anti-HIV activity of a novel aminoglycoside-arginine conjugate

scientific article

Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals.

scientific article

Anti-human immunodeficiency virus activity of novel aminoglycoside-arginine conjugates at early stages of infection

scientific article

Antibodies and Antibody Derivatives: New Partners in HIV Eradication Strategies

article

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells

article

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

scientific article published on 16 July 2016

Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

scientific article

Assessing main death pathways in T lymphocytes from HIV infected individuals.

scientific article

Association between HIV replication and cholesterol in peripheral blood mononuclear cells in HIV-infected patients interrupting HAART.

scientific article

Attacking the HIV Reservoir from the Immune and Viral Perspective ⬇️

scientific article published on March 1, 2013

Brief Report: Impaired CD4 T-Cell Response to Autophagy in Treated HIV-1-Infected Individuals.

scientific article

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

scientific article published on 01 April 2010

CD4 recovery is associated with genetic variation in IFNγ and IL19 genes

scientific article published on 03 August 2019

CD4(+) and CD8(+) T cell death during human immunodeficiency virus infection in vitro

scientific article published in July 2001

CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease

scientific article published on 29 May 2003

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

scientific article

Cell-Surface-Expressed HIV-1 Envelope Induces the Death of CD4 T Cells during GP41-Mediated Hemifusion-like Events

scientific article published on 01 January 2003

Changes in T-cell subsets in HIV-HCV-coinfected patients during pegylated interferon-alpha2a plus ribavirin treatment

scientific article published in January 2010

Chemokine and chemokine receptor expression after combined anti-HIV-1 interleukin-2 therapy

article

Child cured of HIV: can this be repeated?

scientific article

Comodulation of CXCR4 and CD26 in human lymphocytes

scientific article (publication date: June 2001)

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

scientific article

Could CD4 capture by CD8+ T cells play a role in HIV spreading?

scientific article published on 25 March 2010

Deep molecular characterization of HIV-1 dynamics under suppressive HAART

scientific article

Detection of SARS-CoV-2 in a cat owned by a COVID-19-affected patient in Spain

scientific article published on 18 September 2020

Different pattern of stool and plasma gastrointestinal damage biomarkers during primary and chronic HIV infection.

scientific article published on 11 June 2019

Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals

scientific article

Differential gene expression in HIV-infected individuals following ART.

scientific article published on 06 August 2013

Dipeptidyl-peptidase IV-beta, a novel form of cell-surface-expressed protein with dipeptidyl-peptidase IV activity

scientific article published on July 1996

Does rapid HIV disease progression prior to combination antiretroviral therapy hinder optimal CD4+ T-cell recovery once HIV-1 suppression is achieved?

scientific article published in November 2015

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

scientific article published on 10 October 2011

Dynamics of CD4 and CD8 T-Cell Subsets and Inflammatory Biomarkers during Early and Chronic HIV Infection in Mozambican Adults

scientific article published in January 2017

Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification

scientific article published in June 2013

Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

scientific article published on 14 May 2013

Elevated humoral response to cytomegalovirus in HIV-infected individuals with poor CD4+ T-cell immune recovery.

scientific article published on 21 September 2017

Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes

scientific article published on February 1998

Evaluation of the cytopathicity (fusion/hemifusion) of patient-derived HIV-1 envelope glycoproteins comparing two effector cell lines

scientific article

Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives

scientific article published in April 2000

Evolution of the gut microbiome following acute HIV-1 infection

article

Exosomes and retroviruses: the chicken or the egg?

scientific article

Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions

scientific article published on 22 February 2013

Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine.

scientific article

Generation of HIV-1 Gag VLPs by transient transfection of HEK 293 suspension cell cultures using an optimized animal-derived component free medium.

scientific article published on 17 May 2013

Genetic variation in CCR2 and CXCL12 genes impacts on CD4 restoration in patients initiating cART with advanced immunesupression

article

Genotypic and phenotypic evolution of HIV type-1 protease during in vitro sequential or concomitant combination of atazanavir and amprenavir

scientific article

Glutaminolysis and lipoproteins are key factors in late immune recovery in successfully treated HIV-infected patients

scientific article published on 29 April 2019

Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals

scientific article published on 24 March 2015

Gut Microbiota Linked to Sexual Preference and HIV Infection.

scientific article

HIV Envelope Glycoprotein-Induced Cell Killing by Apoptosis Is Enhanced with Increased Expression of CD26 in CD4+T Cells

article

HIV Research for Prevention 2018: From Research to Impact Conference Summary and Highlights

scientific article published on 29 May 2019

HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?

scientific article

HIV exposed seronegative individuals show antibodies specifically recognizing native HIV envelope glycoprotein

scientific article published on June 2013

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.

scientific article

HIV-1 Envelope gp120 and Viral Particles Block Adenosine Deaminase Binding to Human CD26 ⬇️

scientific article published on January 1, 1997

HIV-1 Nef Targets HDAC6 to Assure Viral Production and Virus Infection

scientific article published on 30 October 2019

HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic

article

HIV-1 envelope glycoproteins-mediated apoptosis is regulated by CD4 dependent and independent mechanisms

scientific article published on January 1997

HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells

scientific article published on November 2008

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

scientific article published on 14 March 2010

HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes.

scientific article

HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization

scientific article

High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cells

scientific article

Higher levels of IL-6, CD4 turnover and Treg frequency are already present before cART in HIV-infected subjects with later low CD4 recovery.

scientific article published on 24 March 2017

Human endogenous retroviruses and cancer

scientific article published in December 2016

IL7RA rs6897932 Polymorphism is Associated with Better CD4+ T-Cell Recovery in HIV Infected Patients Starting Combination Antiretroviral Therapy

scientific article published on 16 June 2019

IP-10 Levels as an Accurate Screening Tool to Detect Acute HIV Infection in Resource-Limited Settings.

scientific article published on 14 August 2017

Identification of V3 loop-binding proteins as potential receptors implicated in the binding of HIV particles to CD4(+) cells.

scientific article

Immunodiscordant responses to HAART--mechanisms and consequences

scientific article

Immunologic Insights on the Membrane Proximal External Region: A Major Human Immunodeficiency Virus Type-1 Vaccine Target.

scientific article published on 19 September 2017

Immunological and virological study of enfuvirtide-treated HIV-positive patients

scientific article

Impact of intensification with raltegravir on HIV-1-infected individuals receiving monotherapy with boosted PIs.

scientific article

Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery

scientific article published on 17 July 2015

Increased rate of HIV-1 entry and its cytopathic effect in CD4+/CXCR4+ T cells expressing relatively high levels of CD26.

scientific article published on June 1998

Inhibition of HIV infection by pseudopeptides blocking viral envelope glycoprotein-mediated membrane fusion and cell death

scientific article

Inhibition of coreceptor-independent cell-to-cell human immunodeficiency virus type 1 transmission by a CD4-immunoglobulin G2 fusion protein

scientific article

Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody

scientific article

Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection

scientific article published on January 2014

Interferon-γ-Inducible Protein 10 (IP-10) as a Screening Tool to Optimize Human Immunodeficiency Virus RNA Monitoring in Resource-Limited Settings.

scientific article published on 19 July 2017

Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individuals

scientific article published on November 2001

Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

scientific article published on 02 August 2016

Learning from drug changes in antiretroviral therapy

scientific article

Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

article

Maturation of blood-derived dendritic cells enhances human immunodeficiency virus type 1 capture and transmission

scientific article

Memory B cell dysregulation in HIV-1-infected individuals.

scientific article published on 2 November 2017

Mitochondrial haplogroup H is related to CD4+ T cell recovery in HIV infected patients starting combination antiretroviral therapy

article

Multiparametric assay to screen and dissect the mode of action of anti-human immunodeficiency virus envelope drugs

scientific article

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Evidence for an autoimmune disease.

scientific article published on 7 April 2018

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

article

On the steps of cell-to-cell HIV transmission between CD4 T cells

scientific article

Predicting Antibody Neutralization Efficacy in Hypermutated Epitopes Using Monte Carlo Simulations

scientific article published on 17 October 2020

Preferential attachment of HIV particles to activated and CD45RO+CD4+ T cells

scientific article published in January 2002

Preserved immune functionality and high CMV-specific T-cell responses in HIV-infected individuals with poor CD4+ T-cell immune recovery

scientific article published on 15 September 2017

Production of HIV-1-based virus-like particles for vaccination: achievements and limits

scientific article published on 01 August 2019

Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif.

scientific article published on 13 January 2017

Pseudopeptide TASP inhibitors of HIV entry bind specifically to a 95-kDa cell surface protein.

scientific article published on March 1997

R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism

article

Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery

scientific article published on November 2012

Rapid HIV progression during acute HIV-1 subtype C infection in a Mozambican patient with atypical seroconversion

scientific article

Reduced fitness of HIV-1 resistant to CXCR4 antagonists

scientific article published on February 2003

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome

scientific article published on 20 March 2013

Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44

article

Secretion of interferon-gamma by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18

scientific article published on 28 August 2008

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

scientific article

Short-term Treatment With Interferon Alfa Diminishes Expression of HIV-1 and Reduces CD4+ T-Cell Activation in Patients Coinfected With HIV and Hepatitis C Virus and Receiving Antiretroviral Therapy

scientific article published on November 2015

Solubilization and molecular characterization of the nitrobenzylthioinosine binding sites from pig kidney brush-border membranes

scientific article published on April 1994

Specific and irreversible cyclopeptide inhibitors of dipeptidyl peptidase IV activity of the T-cell activation antigen CD26.

scientific article

Specific binding of adenosine deaminase but not HIV-1 transactivator protein Tat to human CD26.

scientific article published on May 1996

Stromal-cell-derived factor 1 prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo

article

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

article

Susceptibility of human lymphoid tissue cultured ex vivo to xenotropic murine leukemia virus-related virus (XMRV) infection

scientific article

Switching From a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen: A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human Immunodeficiency Virus-infecte

scientific article published on 01 September 2019

The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis

scientific article

The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE.

scientific article

The HIV-1 gp120 inhibits the binding of adenosine deaminase to CD26 by a mechanism modulated by CD4 and CXCR4 expression

scientific article (publication date: 14 July 2000)

The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype

scientific article published on 14 February 2012

The effect of atorvastatin treatment on HIV-1-infected patients interrupting antiretroviral therapy

scientific article published in February 2006

The effect of cell subset isolation method on gene expression in leukocytes.

scientific article published on 20 September 2013

The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling

article

The infectious synapse formed between mature dendritic cells and CD4(+) T cells is independent of the presence of the HIV-1 envelope glycoprotein

scientific article

The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses

scientific article published on 19 April 2011

Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.

scientific article published on 28 September 2011

Treatment of monocytes with interleukin (IL)-12 plus IL-18 stimulates survival, differentiation and the production of CXC chemokine ligands (CXCL)8, CXCL9 and CXCL10.

scientific article

Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm

article published in the Proceedings of the National Academy of Sciences of the United States of America

Variable endothelial cell function restoration after initiation of two antiretroviral regimens in HIV-infected individuals

scientific article published on 22 March 2017

Viral Characteristics Associated with the Clinical Nonprogressor Phenotype Are Inherited by Viruses from a Cluster of HIV-1 Elite Controllers.

scientific article published on 10 April 2018

Viral infection: Moving through complex and dynamic cell-membrane structures.

scientific article published on July 2011

Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function

scientific article (publication date: 2012)

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

scientific article published on 27 September 2017

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