List of works - Maria Carmen Puertas

A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors

scientific article published on 12 October 2011

A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy.

scientific article

An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults

scientific article published on 18 November 2021

Anti-peripherin B lymphocytes are positively selected during diabetogenesis

scientific article published on 23 April 2008

Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

scientific article published on 04 May 2020

CCR5 Δ32 homozygous cord blood allogeneic transplantation in a patient with HIV: a case report

scientific article

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

scientific article

Capture of cell-derived microvesicles (exosomes and apoptotic bodies) by human plasmacytoid dendritic cells

scientific article published on 08 February 2012

Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy

scientific article published on 13 August 2012

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

scientific article

Definition of the viral targets of protective HIV-1-specific T cell responses

scientific article published on 7 December 2011

Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages

article

Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals

scientific article

Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification

scientific article published in June 2013

Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

scientific article published on 14 May 2013

Effect of lithium on HIV-1 expression and proviral reservoir size in the CD4+ T cells of antiretroviral therapy suppressed patients

scientific article published on September 2014

Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals

scientific article published on 27 January 2014

Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029.

scientific article

Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility.

scientific article published on 20 May 2009

Establishment and Replenishment of the Viral Reservoir in Perinatally HIV-1-infected Children Initiating Very Early Antiretroviral Therapy

scientific article

Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

scientific article published on May 2017

Exosomes and retroviruses: the chicken or the egg?

scientific article

Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein.

scientific article published on 22 October 2008

HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?

scientific article

HIV-1 Capture and Antigen Presentation by Dendritic Cells: Enhanced Viral Capture Does Not Correlate with Better T Cell Activation

article

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

scientific article published on 14 March 2010

IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

scientific article published in December 2004

Increasing Diagnostic Uncertainties in Children With In Utero HIV Infection

scientific article published on 01 August 2019

Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection

scientific article published on January 2014

Islet-infiltrating B-cells in nonobese diabetic mice predominantly target nervous system elements.

scientific article published in January 2005

Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

scientific article published on 02 August 2016

Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure

scientific article published on 23 August 2010

Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region

scientific article published on 17 July 2008

Natural killer cells are required for accelerated type 1 diabetes driven by interferon-beta.

scientific article

Novel two-round phenotypic assay for protease inhibitor susceptibility testing of recombinant and primary HIV-1 isolates.

scientific article

Phenotype and Functional Characteristics of Islet-Infiltrating B-Cells Suggest the Existence of Immune Regulatory Mechanisms in Islet Milieu

scientific article published on 01 April 2007

Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery

scientific article published on November 2012

Raltegravir susceptibility and fitness progression of HIV type-1 integrase in patients on long-term antiretroviral therapy.

scientific article

Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNbeta.

scientific article published on 10 August 2006

Relationship between CCR5(WT/Δ32) heterozygosity and HIV-1 reservoir size in adolescents and young adults with perinatally acquired HIV-1 infection.

scientific article

Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical human immunodeficiency virus type 1 isolate with a deletion of codon 69 in the reverse transcriptase coding region

scientific article published on 21 February 2007

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

Sensitive quantification of the HIV-1 reservoir in gut-associated lymphoid tissue

scientific article

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

scientific article published on 14 April 2020

Short-term Treatment With Interferon Alfa Diminishes Expression of HIV-1 and Reduces CD4+ T-Cell Activation in Patients Coinfected With HIV and Hepatitis C Virus and Receiving Antiretroviral Therapy

scientific article published on November 2015

Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides

scientific article

Switching From a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen: A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human Immunodeficiency Virus-infecte

scientific article published on 01 September 2019

The HIV-1 integrase genotype strongly predicts raltegravir susceptibility but not viral fitness of primary virus isolates

scientific article published in January 2010

The infectious synapse formed between mature dendritic cells and CD4(+) T cells is independent of the presence of the HIV-1 envelope glycoprotein

scientific article

Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.

scientific article published on 28 September 2011

Viral and inflammatory markers in cerebrospinal fluid of patients with HIV-1-associated neurocognitive impairment during antiretroviral treatment switch.

scientific article published on 27 February 2015

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

scientific article published on 27 September 2017

List of works by Maria Carmen Puertas

A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors

A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy.

An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults

Anti-peripherin B lymphocytes are positively selected during diabetogenesis

Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

CCR5 Δ32 homozygous cord blood allogeneic transplantation in a patient with HIV: a case report

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

Capture of cell-derived microvesicles (exosomes and apoptotic bodies) by human plasmacytoid dendritic cells

Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

Definition of the viral targets of protective HIV-1-specific T cell responses

Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages

Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals

Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification

Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

Effect of lithium on HIV-1 expression and proviral reservoir size in the CD4+ T cells of antiretroviral therapy suppressed patients

Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals

Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029.

Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility.

Establishment and Replenishment of the Viral Reservoir in Perinatally HIV-1-infected Children Initiating Very Early Antiretroviral Therapy

Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

Exosomes and retroviruses: the chicken or the egg?

Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein.

HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?

HIV-1 Capture and Antigen Presentation by Dendritic Cells: Enhanced Viral Capture Does Not Correlate with Better T Cell Activation

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

Increasing Diagnostic Uncertainties in Children With In Utero HIV Infection

Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection

Islet-infiltrating B-cells in nonobese diabetic mice predominantly target nervous system elements.

Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.

Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure

Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region

Natural killer cells are required for accelerated type 1 diabetes driven by interferon-beta.

Novel two-round phenotypic assay for protease inhibitor susceptibility testing of recombinant and primary HIV-1 isolates.

Phenotype and Functional Characteristics of Islet-Infiltrating B-Cells Suggest the Existence of Immune Regulatory Mechanisms in Islet Milieu

Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery

Raltegravir susceptibility and fitness progression of HIV type-1 integrase in patients on long-term antiretroviral therapy.

Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNbeta.

Relationship between CCR5(WT/Δ32) heterozygosity and HIV-1 reservoir size in adolescents and young adults with perinatally acquired HIV-1 infection.

Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical human immunodeficiency virus type 1 isolate with a deletion of codon 69 in the reverse transcriptase coding region

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

Sensitive quantification of the HIV-1 reservoir in gut-associated lymphoid tissue

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

Short-term Treatment With Interferon Alfa Diminishes Expression of HIV-1 and Reduces CD4+ T-Cell Activation in Patients Coinfected With HIV and Hepatitis C Virus and Receiving Antiretroviral Therapy

Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides

Switching From a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen: A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human Immunodeficiency Virus-infecte

The HIV-1 integrase genotype strongly predicts raltegravir susceptibility but not viral fitness of primary virus isolates

The infectious synapse formed between mature dendritic cells and CD4(+) T cells is independent of the presence of the HIV-1 envelope glycoprotein

Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.

Viral and inflammatory markers in cerebrospinal fluid of patients with HIV-1-associated neurocognitive impairment during antiretroviral treatment switch.

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.