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List of works by David Stegner

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis.

scientific article

ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia

scientific article published on 27 June 2018

Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state

scientific article published on 22 June 2012

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

scientific article

CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice.

scientific article published on 23 August 2017

Cholesterol loss during glutamate-mediated excitotoxicity

scientific article published on 17 February 2012

Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation

scientific article

Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect

scientific article published on 6 March 2015

Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases

scientific article published on 19 July 2010

Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.

scientific article

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice.

scientific article

Imaging platelet biogenesis in vivo

Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1.

scientific article published on 5 January 2010

Impaired brain development and reduced cognitive function in phospholipase D-deficient mice

scientific article published on 9 May 2014

Intravital imaging of megakaryocytes

scientific article published on 10 March 2020

Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells - a comparative study

scientific article published on 29 July 2020

Mechanistic explanation for platelet contribution to cancer metastasis

scientific article published on May 2014

Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect

scientific article published on 04 September 2014

Munc13-4-mediated secretion is essential for infarct progression but not intracranial hemostasis in acute stroke.

scientific article

Neutrophils mediate edema formation but not mechanical allodynia during zymosan-induced inflammation

scientific article published on 20 February 2014

Normal Platelet Integrin Function in Mice Lacking Hydrogen Peroxide-Induced Clone-5 (Hic-5)

scientific article

Orai1 controls C5a-induced neutrophil recruitment in inflammation.

scientific article published on 15 May 2015

Orai1-induced store-operated Ca2+entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets

scientific article published on 01 April 2014

PLD1 participates in BDNF-induced signalling in cortical neurons

scientific article

Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report

scientific article published on 18 July 2013

Phospholipase D is a central regulator of collagen I-induced cytoskeletal rearrangement and podosome formation in megakaryocytes

scientific article published on 05 July 2014

Phospholipase D1 facilitates second-phase myoblast fusion and skeletal muscle regeneration

scientific article

Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle

scientific article published on 19 November 2013

Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis

scientific article published on 5 June 2014

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

scientific article published on 01 November 2019

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

scientific article published on 01 April 2019

Platelet receptor signaling in thrombus formation

scientific article

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice

scientific article published on 11 January 2017

Protein kinase Cι/λ is dispensable for platelet function in thrombosis and hemostasis in mice

scientific article

Redundant functions of phospholipases D1 and D2 in platelet α-granule release

scientific article published on 01 November 2012

Roles of platelet STIM1 and Orai1 in glycoprotein VI- and thrombin-dependent procoagulant activity and thrombus formation

scientific article

STIM1 is essential for Fcgamma receptor activation and autoimmune inflammation

scientific article

STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia

scientific article published on 3 December 2014

STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death

scientific article

SePARating thrombosis and hemostasis?

scientific article published on 21 July 2016

Size does matter: VWF in MI.

scientific article published in December 2012

Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.

scientific article published on March 2015

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

scientific article

Targeting glycoprotein VI and the immunoreceptor tyrosine-based activation motif signaling pathway

scientific article

The Nbeal2(-/-) mouse as a model for the gray platelet syndrome

scientific article

The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis.

scientific article published on 8 September 2017

Thrombopoiesis is spatially regulated by the bone marrow vasculature.

scientific article

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