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List of works by Elly M Hol

A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques

scientific article (publication date: 19 April 2011)

A direct androgenic involvement in the expression of human corticotropin-releasing hormone.

scientific article published in June 2006

ACTH-related peptides: receptors and signal transduction systems involved in their neurotrophic and neuroprotective actions

scientific article published on January 1995

Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases

scientific article published on 15 June 2004

Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP.

scientific article published in September 2005

Adult human subventricular, subgranular, and subpial zones contain astrocytes with a specialized intermediate filament cytoskeleton

scientific article published on December 2005

Alzheimer's associated variant ubiquitin causes inhibition of the 26S proteasome and chaperone expression

scientific article published in July 2003

Alzheimer-associated APP+1 transgenic mice: frameshift beta-amyloid precursor protein is secreted in cerebrospinal fluid without inducing neuropathology

scientific article

Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease.

scientific article published on July 2007

Cells over-expressing EAAT2 protect motoneurons from excitotoxic death in vitro

scientific article published in October 2003

Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome

scientific article published on January 2013

Co-expression of tyrosine hydroxylase and GTP cyclohydrolase I in arginine vasopressin-synthesizing neurons of the human supraoptic nucleus demonstrated by laser microdissection and real-time PCR

scientific article

Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model

scientific article published on 12 December 2012

Deep brain stimulation and the role of astrocytes.

scientific article published on 31 May 2011

Defective glial maturation in vanishing white matter disease.

scientific article

Dementia in Parkinson's Disease Correlates withα-Synuclein Pathology but Not with Cortical Astrogliosis ⬇️

scientific article published on April 22, 2012

Developmental lineage of cell types in cortical dysplasia with balloon cells

scientific article published on 01 September 2007

Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model

scientific article published on 19 January 2012

Diminished aromatase immunoreactivity in the hypothalamus, but not in the basal forebrain nuclei in Alzheimer's disease

scientific article

Distinct non-inflammatory signature of microglia in post-mortem brain tissue of patients with major depressive disorder

scientific article published on 07 October 2020

Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease

scientific article published on 3 April 2007

Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial

scientific article published on June 2008

Enteric GFAP expression and phosphorylation in Parkinson's disease

scientific article published on 6 June 2014

Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue

scientific article published in February 2013

Expression patterns of glial fibrillary acidic protein (GFAP)-delta in epilepsy-associated lesional pathologies.

scientific article

Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40.

scientific article published on August 2004

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

scientific article published in January 1998

Frameshifted beta-amyloid precursor protein (APP+1) is a secretory protein, and the level of APP+1 in cerebrospinal fluid is linked to Alzheimer pathology

scientific article

GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease ⬇️

scientific article published on August 13, 2012

GFAP in health and disease.

scientific article

GFAPdelta immunostaining improves visualization of normal and pathologic astrocytic heterogeneity.

scientific article

GFAPdelta in radial glia and subventricular zone progenitors in the developing human cortex

scientific article published in January 2010

GFAPδ expression in glia of the developmental and adolescent mouse brain

scientific article

Hand motor activity, cognition, mood, and the rest-activity rhythm in dementia: a clustered RCT.

scientific article

Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry

scientific article published on 17 December 2018

Identification of regeneration-associated genes after central and peripheral nerve injury in the adult rat

scientific article

Immunohistochemical characterization of the out-of frame splice variants GFAP Delta164/Deltaexon 6 in focal lesions associated with chronic epilepsy

scientific article published on 28 April 2010

Importance of GFAP isoform-specific analyses in astrocytoma

scientific article published on 22 January 2019

In vivo targeting of subventricular zone astrocytes.

scientific article published on 02 May 2010

Intermediate filament transcription in astrocytes is repressed by proteasome inhibition.

scientific article published on 30 March 2009

Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin

scientific article published on 28 August 2008

Longterm quiescent cells in the aged human subventricular neurogenic system specifically express GFAP-delta.

scientific article published on 30 January 2010

Migrating neuroblasts in the adult human brain: a stream reduced to a trickle.

scientific article

Molecular misreading: a new type of transcript mutation expressed during aging.

scientific article

Molecular misreading: the frequency of dinucleotide deletions in neuronal mRNAs for beta-amyloid precursor protein and ubiquitin B.

scientific article

Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.

scientific article published in December 2001

Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration

scientific article

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

scientific article published on 29 April 2002

Mutations in RNA: a first example of molecular misreading in Alzheimer's disease

scientific article published in August 1998

Neuronal expression of GFAP in patients with Alzheimer pathology and identification of novel GFAP splice forms

scientific article published in September 2003

Nimodipine protects cultured spinal cord neurones from depolarization-induced inhibition of neurite outgrowth

scientific article published on 01 April 1993

Observation of hand movements by older persons with dementia: effects on cognition: a pilot study

scientific article

Polyglutamine expansion accelerates the dynamics of ataxin-1 and does not result in aggregate formation

scientific article

Presenilin mouse and zebrafish models for dementia: focus on neurogenesis

scientific article

Proteasome subunit proteins and neuropathology in tauopathies and synucleinopathies: Consequences for proteomic analyses

scientific article published in March 2008

Protection by an ACTH4-9 analogue against the toxic effects of cisplatin and taxol on sensory neurons and glial cells in vitro

scientific article published on October 1994

Protein quality control in Alzheimer's disease by the ubiquitin proteasome system.

scientific article

Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models

scientific article published on 23 April 2013

Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions

scientific article

Regulation of the LIM-type homeobox gene islet-1 during neuronal regeneration

scientific journal article

Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

scientific article published on 24 February 2022

Specific human astrocyte subtype revealed by affinity purified GFAP antibody; unpurified serum cross-reacts with neurofilament-L in Alzheimer

scientific article

Stimulation by melanocortins of neurite outgrowth from spinal and sensory neurons in vitro

scientific article published on 01 November 1992

Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease.

scientific article published on July 2009

The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury

scientific article published in January 1993

The neuronal ubiquitin-proteasome system: murine models and their neurological phenotype.

scientific article published on 18 March 2008

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain

scientific article published on 01 November 2011

The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B+1.

scientific article

Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson's disease

scientific article published on 03 June 2019

Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives

scientific article published on January 2010

Ubiquitin proteasome system as a pharmacological target in neurodegeneration.

scientific article published on September 2006

Walking the line: a randomised trial on the effects of a short term walking programme on cognition in dementia

scientific article published in July 2009

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

scientific article published in February 2006

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