List of works - Mark R Wills

A highly reproducible quantitative viral outgrowth assay for the measurement of the replication-competent latent HIV-1 reservoir

scientific article published on 24 February 2017

Analysis of Cytotoxic T-Cell Responses to Human Cytomegalovirus Infection

article

Antigenic characterization of the live attenuated Japanese encephalitis vaccine virus SA14-14-2: a comparison with isolates of the virus covering a wide geographic area

scientific article published on January 1992

CMV and Immunosenescence: from basics to clinics

scientific article published on 31 October 2012

CMV immune evasion and manipulation of the immune system with aging.

scientific article

Comparison of nucleotide and deduced amino acid sequence of the 5' non-coding region and structural protein genes of the wild-type Japanese encephalitis virus strain SA14 and its attenuated vaccine derivatives

scientific article published in June 1994

Corrigendum: The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6.

scientific article published on 26 September 2016

Differential costimulation through CD137 (4-1BB) restores proliferation of human virus-specific "effector memory" (CD28(-) CD45RA(HI)) CD8(+) T cells

scientific article published on 18 September 2007

Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation

scientific article published on 15 January 2019

Diverse specificities, phenotypes, and antiviral activities of cytomegalovirus-specific CD8+ T cells

scientific article

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity

scholarly article

Effect of administration of sodium aurothiomalate on the virulence of yellow fever viruses in adult mice

scientific article published on December 1990

Efficient human cytomegalovirus reactivation is maturation dependent in the Langerhans dendritic cell lineage and can be studied using a CD14+ experimental latency model.

scientific article

Extracellular Lactate: A Novel Measure of T Cell Proliferation

scientific article published on 29 December 2017

Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

scientific article

Generation, maintenance and tissue distribution of T cell responses to human cytomegalovirus in lytic and latent infection

scientific article published on 20 March 2019

HCMV activation of ERK-MAPK drives a multi-factorial response promoting the survival of infected myeloid progenitors

scientific article published on January 2017

How understanding immunology contributes to managing CMV disease in immunosuppressed patients: now and in future

scientific article published on 21 April 2015

Human CD28-CD8+ T cells contain greatly expanded functional virus-specific memory CTL clones.

scientific article published in June 1999

Human Cytomegalovirus (HCMV)-Specific CD4+ T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro ⬇️

scientific article published on 4 January 2017

Human Cytomegalovirus Delays Neutrophil Apoptosis and Stimulates the Release of a Prosurvival Secretome

scientific article published on 25 September 2017

Human cytomegalovirus and immunopathology.

scientific article

Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis

scientific article published on December 2005

Human cytomegalovirus immunity and immune evasion

scientific article

Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells

scientific article

Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells.

scientific article published on 13 July 2016

Human cytomegalovirus-specific immunity following haemopoietic stem cell transplantation ⬇️

scientific article published on December 1, 2003

Human virus-specific CD8+ CTL clones revert from CD45ROhigh to CD45RAhigh in vivo: CD45RAhighCD8+ T cells comprise both naive and memory cells

scientific article published on June 1999

Identification of envelope protein epitopes that are important in the attenuation process of wild-type yellow fever virus ⬇️

scientific article published on July 1, 1992

Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: analysis of the human cytomegalovirus-specific CD8(+) T cell response.

scientific article published in June 2002

Immune evasion proteins gpUS2 and gpUS11 of human cytomegalovirus incompletely protect infected cells from CD8 T cell recognition

scientific article published on 30 June 2009

Immunobiology and host response

Immunogenicity of experimental live attenuated Japanese encephalitis vaccine viruses and comparison with wild-type strains using monoclonal and polyclonal antibodies

scientific article published on January 1992

Immunogenicity of wild-type and vaccine strains of Japanese encephalitis virus and the effect of haplotype restriction on murine immune responses

scientific article published on January 1993

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

scientific article published on 7 September 2010

In vitro homotypic and heterotypic interference by defective interfering particles of West Nile virus

scientific article published on November 1991

Innovations in the quantitative virus outgrowth assay and its use in clinical trials.

scientific article published on 21 December 2017

Intracellular sequestration of the NKG2D ligand ULBP3 by human cytomegalovirus.

scientific article

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner

scientific article published on 13 April 2020

LPS promotes a monocyte phenotype permissive for human cytomegalovirus immediate-early gene expression upon infection but not reactivation from latency

scientific article

Large HIV-specific CD8 cytotoxic T-lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy

scientific article published in May 2006

Large clonal expansions of human virus-specific memory cytotoxic T lymphocytes within the CD57+ CD28- CD8+ T-cell population

scientific article

Late diversification in the clonal composition of human cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic stem cell transplantation

article

Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection

scientific article published on 5 December 2017

Latency-associated viral interleukin-10 (IL-10) encoded by human cytomegalovirus modulates cellular IL-10 and CCL8 Secretion during latent infection through changes in the cellular microRNA hsa-miR-92a

scientific article published on 24 September 2014

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells.

scientific article published on 26 June 2017

Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18.

scientific article published on 6 January 2016

Long-term stable expanded human CD4+ T cell clones specific for human cytomegalovirus are distributed in both CD45RAhigh and CD45ROhigh populations.

scientific article published in November 2004

Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells

scientific article published on 29 March 2017

NKG2D ligand MICA is retained in the cis-Golgi apparatus by human cytomegalovirus protein UL142.

scientific article published on 30 September 2009

Nanopore sequencing and full genome de novo assembly of human cytomegalovirus TB40/E reveals clonal diversity and structural variations

No evidence of ongoing evolution in replication competent latent HIV-1 in a patient followed up for two years

scientific article published on 8 February 2018

Passage of Japanese encephalitis virus in HeLa cells results in attenuation of virulence in mice

scientific article published on November 1995

Preface

scientific article published on 13 November 2010

Progressive loss of IL-2-expandable HIV-1-specific cytotoxic T lymphocytes during asymptomatic HIV infection.

scientific article published in November 1998

Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus

scientific article

Regulation of NKG2D ligand gene expression.

scientific article published on March 2006

Report from the second cytomegalovirus and immunosenescence workshop

scientific article published on 28 October 2011

Status of Cytomegalovirus Prevention and Treatment in 2000.

scientific article

The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6

scientific article published on 05 August 2016

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL.

scientific article

The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?

scientific article

The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo

scientific article published on March 1999

Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells

scientific article published on 19 April 2016

Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules

article published in the Proceedings of the National Academy of Sciences of the United States of America

Variation in the biological function of envelope protein epitopes of yellow fever vaccine viruses detected with monoclonal antibodies

scientific article

List of works by Mark R Wills

A highly reproducible quantitative viral outgrowth assay for the measurement of the replication-competent latent HIV-1 reservoir

Analysis of Cytotoxic T-Cell Responses to Human Cytomegalovirus Infection

Antigenic characterization of the live attenuated Japanese encephalitis vaccine virus SA14-14-2: a comparison with isolates of the virus covering a wide geographic area

CMV and Immunosenescence: from basics to clinics

CMV immune evasion and manipulation of the immune system with aging.

Comparison of nucleotide and deduced amino acid sequence of the 5' non-coding region and structural protein genes of the wild-type Japanese encephalitis virus strain SA14 and its attenuated vaccine derivatives

Corrigendum: The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6.

Differential costimulation through CD137 (4-1BB) restores proliferation of human virus-specific "effector memory" (CD28(-) CD45RA(HI)) CD8(+) T cells

Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation

Diverse specificities, phenotypes, and antiviral activities of cytomegalovirus-specific CD8+ T cells

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity

Effect of administration of sodium aurothiomalate on the virulence of yellow fever viruses in adult mice

Efficient human cytomegalovirus reactivation is maturation dependent in the Langerhans dendritic cell lineage and can be studied using a CD14+ experimental latency model.

Extracellular Lactate: A Novel Measure of T Cell Proliferation

Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

Generation, maintenance and tissue distribution of T cell responses to human cytomegalovirus in lytic and latent infection

HCMV activation of ERK-MAPK drives a multi-factorial response promoting the survival of infected myeloid progenitors

How understanding immunology contributes to managing CMV disease in immunosuppressed patients: now and in future

Human CD28-CD8+ T cells contain greatly expanded functional virus-specific memory CTL clones.

Human Cytomegalovirus (HCMV)-Specific CD4+ T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro ⬇️

Human Cytomegalovirus Delays Neutrophil Apoptosis and Stimulates the Release of a Prosurvival Secretome

Human cytomegalovirus and immunopathology.

Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis

Human cytomegalovirus immunity and immune evasion

Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells

Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells.

Human cytomegalovirus-specific immunity following haemopoietic stem cell transplantation ⬇️

Human virus-specific CD8+ CTL clones revert from CD45ROhigh to CD45RAhigh in vivo: CD45RAhighCD8+ T cells comprise both naive and memory cells

Identification of envelope protein epitopes that are important in the attenuation process of wild-type yellow fever virus ⬇️

Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: analysis of the human cytomegalovirus-specific CD8(+) T cell response.

Immune evasion proteins gpUS2 and gpUS11 of human cytomegalovirus incompletely protect infected cells from CD8 T cell recognition

Immunobiology and host response

Immunogenicity of experimental live attenuated Japanese encephalitis vaccine viruses and comparison with wild-type strains using monoclonal and polyclonal antibodies

Immunogenicity of wild-type and vaccine strains of Japanese encephalitis virus and the effect of haplotype restriction on murine immune responses

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

In vitro homotypic and heterotypic interference by defective interfering particles of West Nile virus

Innovations in the quantitative virus outgrowth assay and its use in clinical trials.

Intracellular sequestration of the NKG2D ligand ULBP3 by human cytomegalovirus.

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner

LPS promotes a monocyte phenotype permissive for human cytomegalovirus immediate-early gene expression upon infection but not reactivation from latency

Large HIV-specific CD8 cytotoxic T-lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy

Large clonal expansions of human virus-specific memory cytotoxic T lymphocytes within the CD57+ CD28- CD8+ T-cell population

Late diversification in the clonal composition of human cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic stem cell transplantation

Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection

Latency-associated viral interleukin-10 (IL-10) encoded by human cytomegalovirus modulates cellular IL-10 and CCL8 Secretion during latent infection through changes in the cellular microRNA hsa-miR-92a

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells.

Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18.

Long-term stable expanded human CD4+ T cell clones specific for human cytomegalovirus are distributed in both CD45RAhigh and CD45ROhigh populations.

Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells

NKG2D ligand MICA is retained in the cis-Golgi apparatus by human cytomegalovirus protein UL142.

Nanopore sequencing and full genome de novo assembly of human cytomegalovirus TB40/E reveals clonal diversity and structural variations

No evidence of ongoing evolution in replication competent latent HIV-1 in a patient followed up for two years

Passage of Japanese encephalitis virus in HeLa cells results in attenuation of virulence in mice

Preface

Progressive loss of IL-2-expandable HIV-1-specific cytotoxic T lymphocytes during asymptomatic HIV infection.

Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus

Regulation of NKG2D ligand gene expression.

Report from the second cytomegalovirus and immunosenescence workshop

Status of Cytomegalovirus Prevention and Treatment in 2000.

The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL.

The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?

The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo

Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells

Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules

Variation in the biological function of envelope protein epitopes of yellow fever vaccine viruses detected with monoclonal antibodies