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List of works by Hans Deckmyn

A Monoclonal Antibody to the α2 Integrin Subunit Cross-Reacts with RGD-Dependent Epitopes in Fibrinogen

scientific article published on 01 August 1993

A Reliable von Willebrand factor: ristocetin cofactor enzyme-linked immunosorbent assay to differentiate between type 1 and type 2 von Willebrand disease

scientific article

A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction

scientific article

A monoclonal antibody directed against human von Willebrand factor induces type 2B-like alterations

scientific article

A monoclonal antibody recognizes a von Willebrand factor domain within the amino-terminal portion of the subunit that modulates the function of the glycoprotein IB- and IIB/IIIA-binding domains

scientific article published on January 1993

A platelet-activating antiglycoprotein Ib monoclonal antibody

scientific article published on 01 November 1997

A probe for capture and Fe3+-induced conformational change of lactoferrin selected from phage displayed peptide libraries.

scientific article published in October 2004

A reliable and reproducible ELISA method to measure ristocetin cofactor activity of von Willebrand factor

scientific article published on 01 January 2000

A thromboxane synthetase inhibitor reorients endoperoxide metabolism in whole blood towards prostacyclin and prostaglandin E2

scientific article published on 01 June 1982

ADAMTS-13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences

scientific article

ADAMTS13 activity to antigen ratio in physiological and pathological conditions associated with an increased risk of thrombosis

scientific article published on 29 June 2007

ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies

scientific article

ADAMTS13 in health and disease

scientific article

ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice.

scientific article

Acquired Bernard-Soulier syndrome: a case with necrotizing vasculitis and thrombosis

scientific article published on 01 January 1999

Activation of alphaIIbbeta3 is a sufficient but also an imperative prerequisite for activation of alpha2beta1 on platelets

scientific article published on 19 September 2006

Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease

scientific article published on 01 January 1983

Affinity comparison of p3 and p8 peptide displaying bacteriophages using surface plasmon resonance

scientific article

Amplified endogenous plasmin activity resolves acute thrombotic thrombocytopenic purpura in mice.

scientific article published on 5 October 2017

An echistatin-like Arg-Gly-Asp (RGD)-containing sequence in the heavy chain CDR3 of a murine monoclonal antibody that inhibits human platelet glycoprotein IIb/IIIa function

scientific article published in July 1994

An integrated fragment based screening approach for the discovery of small molecule modulators of the VWF-GPIbα interaction.

scientific article

An open conformation of ADAMTS13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura.

scientific article published on 9 December 2017

Anti-vWf antibodies induce GPIbalpha and FcgammaRII mediated platelet aggregation only at low shear forces

scientific article published in December 2001

Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function

scientific article published on 01 March 2020

Antiplatelet drugs

scientific article published on 30 May 2008

Antithrombotic effect of platelet glycoprotein Ib-blocking monoclonal antibody Fab fragments in nonhuman primates.

scientific article

Apparent heterogeneity in the pIII-peptide fusion protein in single-phage clones isolated from peptide libraries.

scientific article

Artificial MiRNA Knockdown of Platelet Glycoprotein lbα: A Tool for Platelet Gene Silencing.

scientific article published on 15 July 2015

BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN

scientific article published in The Lancet

Binding of von Willebrand factor to collagen and glycoprotein Ibalpha, but not to glycoprotein IIb/IIIa, contributes to ischemic stroke in mice--brief report

scientific article published on 8 July 2010

Blood changes and enhanced thromboxane and 6-keto prostaglandin F1 alpha production in experimental acute Plasmodium bergei infection in hamsters

scientific article

Blood platelet biochemistry

scientific article

COMBINING ANTIPLATELET AGENTS: POTENTIATION BETWEEN ASPIRIN AND DIPYRIDAMOLE

scientific article published in The Lancet

Calin from Hirudo medicinalis, an inhibitor of platelet adhesion to collagen, prevents platelet-rich thrombosis in hamsters

scientific article

Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions

scientific article published on 01 February 1995

Characterisation of a novel series of aprotinin-derived anticoagulants. II. Comparative antithrombotic effects on primary thrombus formation in vivo

scientific article published on 01 August 1995

Characterization of N,N'-bis(3-picolyl)-4-methoxy-isophtalamide (picotamide) as a dual thromboxane synthase inhibitor/thromboxane A2 receptor antagonist in human platelets

scientific article published on 01 June 1989

Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13

scientific article published on 15 May 2018

Choline Transporter-Like Protein-2: New von Willebrand Factor-Binding Partner Involved in Antibody-Mediated Neutrophil Activation and Transfusion-Related Acute Lung Injury

scientific article

Chromato-panning: an efficient new mode of identifying suitable ligands from phage display libraries

scientific article

Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin α2β1 and glycoprotein VI

scientific article published on 29 September 2008

Continuous inhibition of serotonin-induced platelet aggregation during chronic ketanserin administration to man can be detected after plasma pH control.

scientific article

Continuous inhibition of the platelet S2-serotonergic receptors during the long term administration of ketanserin

scientific article published on 01 June 1986

Contribution of platelets and the vessel wall to the antithrombotic effects of a single bolus injection of Fab fragments of the antiplatelet GPIIb/IIIa antibody 7E3 in a canine arterial eversion graft preparation

scientific article published on 01 March 1994

Coronary artery in-stent stenosis persists despite inhibition of the von Willebrand factor--collagen interaction in baboons.

scientific article

Decreased ADAMTS-13 (A disintegrin-like and metalloprotease with thrombospondin type 1 repeats) is associated with a poor prognosis in sepsis-induced organ failure*

scientific article published on 01 October 2007

Deficiency of von Willebrand factor protects mice from ischemic stroke

scientific article

Desmopressin treatment improves platelet function under flow in patients with postoperative bleeding

scientific article published on 11 June 2015

Determination of the ADAMTS13 antigen and its activity in TTP patients and carriers

scientific article

Development and screening of epoxy-spacer-phage cryogels for affinity chromatography: Enhancing the binding capacity

scientific article published on 4 May 2017

Development of a high-throughput ELISA assay for platelet function testing using platelet-rich plasma or whole blood.

scientific article published on 27 May 2010

Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs.

scientific article published on September 2006

Dipyridamole inhibits platelet aggregation in whole blood

scientific article published on 01 December 1983

Distinct sequences of the glycoprotein Ib-binding domain of von Willebrand factor involved in shear induced platelet aggregation

scientific article published on 01 January 1998

Disturbed platelet aggregation to collagen associated with an antibody against an 85- to 90-Kd platelet glycoprotein in a patient with prolonged bleeding time ⬇️

scientific article published on March 15, 1992

Effects of thromboxane A2 on lymphocyte proliferation

scientific article published in February 1985

Enkephalins modify granulocyte-endothelial interactions by stimulating prostacyclin production.

scientific article published in August 1983

Epinephrine induces a late thromboxane-dependent platelet shape change and enhances synergistically the shape change induced by other platelet agonists

scientific article published on 01 January 1996

Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.

scientific article

Experimental indication for the existence of multiple Trp rotamers in von Willebrand Factor A3 domain

scientific article published in November 2004

False positive results in chimeraplasty for von Willebrand Disease

scientific article published on 2 February 2006

Fast and reproducible vascular neointima formation in the hamster carotid artery: effects of trapidil and captopril

scientific article published on 01 December 1995

Fc-independent cross-linking of a novel platelet membrane protein by a monoclonal antibody causes platelet activation

scientific article published on 01 July 1994

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets.

scientific article published on 4 December 2017

Fc-receptor dependent platelet aggregation induced by monoclonal antibodies against platelet glycoprotein Ib or von Willebrand factor

scientific article (publication date: April 2001)

Fluorescent labeling of platelets with polyanionic fluorescein derivatives

scientific article published in August 2009

Functional effects of human antiplatelet antibodies

scientific article

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

scientific article

Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura

scientific article

Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques

scientific article (publication date: March 2007)

Guanine nucleotide-dependent inhibition of phospholipase C in human endothelial cells

scientific article published in Journal of Biological Chemistry

Guanine nucleotides stimulate soluble phosphoinositide-specific phospholipase C in the absence of membranes

scientific article published in December 1986

High and long-term von Willebrand factor expression after Sleeping Beauty transposon-mediated gene therapy in a mouse model of severe von Willebrand disease

scientific article published on 29 December 2017

How does agkicetin-C bind on platelet glycoprotein Ibalpha and achieve its platelet effects?

scientific article

Human platelet aggregation by murine monoclonal antiplatelet antibodies is subtype-dependent

scientific article published on 01 April 1993

Human platelets produced in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice upon transplantation of human cord blood CD34+ cells are functionally active in an ex vivo flow model of thrombosis

article

Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains

scientific article published on 22 August 2005

Identification of a VWF peptide antagonist that blocks platelet adhesion under high shear conditions by selectively inhibiting the VWF-collagen interaction

scientific article

Identification of a collagen-binding protein from Necator americanus by using a cDNA-expression phage display library

scientific article

Identification of a small molecule that modulates platelet glycoprotein Ib-von Willebrand factor interaction

scientific article

Identification of peptides, selected by phage display technology, that inhibit von Willebrand factor binding to collagen.

scientific article

Identification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.

scientific article published on 4 October 2004

Immobilised peptide displaying phages as affinity ligands. Purification of lactoferrin from defatted milk

scientific article published on 10 October 2005

Immunomodulatory effects of treatment with naproxen in patients with rheumatic disease

scientific article published on 01 March 1986

Improved platelet survival after cold storage by prevention of glycoprotein Ibα clustering in lipid rafts.

scientific article published on 24 June 2012

In vivo von Willebrand factor size heterogeneity in spite of the clinical deficiency of ADAMTS-13.

scientific article published in December 2011

Inactivation of ADAMTS13 by plasmin as a potential cause of thrombotic thrombocytopenic purpura.

scientific article

Influence of a vitamin E-deficient diet on prostacyclin production by mesometrial triangles and aortic rings from nondiabetic and diabetic pregnant rats

scientific article published on 01 January 1985

Influence of prostaglandin E2 and indomethacin on interferon-? production by cultured peripheral blood leukocytes of multiple sclerosis patients and healthy donors

article

Inherited traits affecting platelet function.

scientific article published on 03 January 2008

Inhibition of Platelet Glycoprotein Ib, Glycoprotein IIb/IIIa, or Both by Monoclonal Antibodies Prevents Arterial Thrombosis in Baboons

scientific article published on 01 February 2002

Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor and Plasminogen Activator Inhibitor-1 Reduces Ischemic Brain Damage in Mice.

scientific article published on 28 July 2016

Inhibition of integrin function by a cyclic RGD-containing peptide prevents neointima formation

scientific article published on 01 November 1994

Inhibition of platelet adhesion to collagen as a new target for antithrombotic drugs

scientific article

Inhibition of the von Willebrand (VWF)-collagen interaction by an antihuman VWF monoclonal antibody results in abolition of in vivo arterial platelet thrombus formation in baboons

scientific article published in May 2002

Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons

scientific article

Inhibitors of the interactions between collagen and its receptors on platelets.

scientific article published on January 2012

Inhibitory and activating human antiplatelet antibodies

scientific article

Inhibitory effect of piracetam on platelet-rich thrombus formation in an animal model

article

Integrin αIIbβ3 and shear-dependent action of glycoprotein ibα stimulate platelet-dependent thrombin formation in stirred plasma

scientific article published on 01 May 2003

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

scientific article

L-652,343, a novel dual cyclo/lipoxygenase inhibitor, inhibits LTB4-production by stimulated human polymorphonuclear cells but not by stimulated human whole blood

article

Lack of synergism between dazoxiben and dipyridamole following administration to man

scientific article published on 01 January 1985

Laser-induced primary and secondary hemostasis dynamics and mechanisms in relation to selective photothermolysis of port wine stains

scientific article

Leukotriene B4 production by stimulated whole blood: Comparative studies with isolated polymorphonuclear cells

article

Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.

scientific article published on 22 September 2015

Local elongation of endothelial cell-anchored von Willebrand factor strings precedes ADAMTS13 protein-mediated proteolysis

scientific article published on 06 September 2011

Long-Term Prevention of Congenital Thrombotic Thrombocytopenic Purpura in ADAMTS13 Knockout Mice by Sleeping Beauty Transposon-Mediated Gene Therapy

scientific article published on 2 March 2017

Low prostacyclin synthetase activity of fetal rat aorta. Progressive increase after birth

scientific article published on 01 October 1983

MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man

scientific article published on 01 October 1993

Macroporous monolithic gels, cryogels, with immobilized phages from phage-display library as a new platform for fast development of affinity adsorbent capable of target capture from crude feeds

scientific article

Major Changes of von Willebrand Factor Multimer Distribution in Cirrhotic Patients with Stable Disease or Acute Decompensation

scientific article published on 04 July 2018

Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom

scientific article published on September 1983

Matrix-specific suppression of integrin activation in shear stress signaling.

scientific article

Measurement of von Willebrand factor antigen in plasma and platelets with an enzyme-linked immunosorbent assay based on two murine monoclonal antibodies

scientific article published on 01 January 1991

Measurement of von Willebrand factor binding to a recombinant fragment of glycoprotein Ibalpha in an enzyme-linked immunosorbent assay-based method: performances in patients with type 2B von Willebrand disease

scientific article published on 01 June 2006

Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity.

scientific article

Model systems of genetically modified platelets

scientific article published on 16 December 2011

Monoclonal antibody IAC-1 is specific for activated alpha2beta1 and binds to amino acids 199 to 201 of the integrin alpha2 I-domain

scientific article published on 23 March 2004

Multiple ways to switch platelet integrins on and off.

scientific article published on 28 May 2008

Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura

scientific article

N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura

scientific article

Neutrophil extracellular traps in ischemic stroke thrombi

scientific article published on 11 July 2017

New approaches for antithrombotic antiplatelet therapies.

scientific article published in September 2004

New insights into von Willebrand disease and platelet function

scientific article published on 07 February 2012

New model of transient strain-dependent autoimmune thrombocytopenia in mice immunized with rat platelets

scientific article

Non-receptor-mediated refractoriness in prostacyclin production by human endothelial cells in a continuous flow system is delayed by a low-molecular-weight plasma fraction devoid of reducing cofactors for peroxidase-catalysed reactions.

scientific article published on December 1990

Normal mechanisms of platelet function

scientific article published on February 1983

On the interaction of fluorophore-encapsulating PEGylated lecithin liposomes with hamster and human platelets

scientific article published on 9 March 2009

Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation

scientific article published on 20 March 2018

PROLONGING PROSTACYCLIN PRODUCTION BY NAFAZATROM OR DIPYRIDAMOLE

scientific article published in The Lancet

Paratope and Epitope Mapping of the Antithrombotic Antibody 6B4 in Complex with Platelet Glycoprotein Ibα

scientific article published in Journal of Biological Chemistry

Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain

scientific article published on 28 November 2005

Partial isolation and function of the prostacyclin regulating plasma factor

scientific article published on 01 October 1985

Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia.

scientific article published on 28 May 2013

Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men

scientific article published on 01 October 1994

Pharmacological manipulation of the thromboxane pathway in blood platelets

scientific article published on June 1990

Phenotypic correction of von Willebrand disease type 3 blood-derived endothelial cells with lentiviral vectors expressing von Willebrand factor

scientific article

Phosphoinositide metabolism in human platelets

scientific article published on January 1987

Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade

scientific article

Plasma glycocalicin as a source of GPIbalpha in the von Willebrand factor ristocetin cofactor ELISA

scientific article published on 01 January 2005

Platelet actuation

scientific article published on 01 September 1995

Platelet adhesion to collagen

scientific article published on January 2011

Platelet aggregation induced by a monoclonal antibody to the A1 domain of von Willebrand factor

scientific article published on 01 May 1998

Platelet antigens and their function.

scientific article published on July 2004

Platelet hypersensitivity to serotonin after prolonged ketanserin intake?

scientific article published on 01 January 1985

Platelet inhibitory activity of prostacyclin in the presence of erythrocytes as studied with the impedance aggregometer

scientific article published on 01 May 1984

Platelet integrin alpha2 I-domain specific antibodies produced via domain specific DNA vaccination combined with variable gene phage display

scientific article published in December 2005

Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα.

scientific article published on 10 June 2013

Platelet microparticle formation and thrombin generation under high shear are effectively suppressed by a monoclonal antibody against GPIba

scientific article published on 01 December 2006

Platelet physiology and antiplatelet agents

scientific article

Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood

scientific article published on 16 October 2003

Platelet sequestration and activation during GalTKO.hCD46 pig lung perfusion by human blood is primarily mediated by GPIb, GPIIb/IIIa, and von Willebrand Factor

scientific article published on 18 May 2016

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice.

scientific article published on 24 July 2015

Platelets and PEGylated lecithin liposomes: when stealth is allegedly picked up on the radar (and eaten).

scientific article published on 20 March 2009

Platelets at work in primary hemostasis.

scientific article published on 14 April 2011

Platelets from flowing blood attach to the inflammatory chemokine CXCL16 expressed in the endothelium of the human vessel wall

scientific article published on 23 April 2015

Principal role of glycoprotein VI in alpha2beta1 and alphaIIbbeta3 activation during collagen-induced thrombus formation

scientific article

Production and nucleotide sequence of an inhibitory human IgM autoantibody directed against platelet glycoprotein Ia/IIa

scientific article published on September 1994

Prolonged inhibition of acute arterial thrombosis by high dosing of a monoclonal anti-platelet glycoprotein IIb/IIIa antibody in a baboon model

article

Promotion of binding of von Willebrand factor to platelet glycoprotein Ib by dimers of ristocetin

scientific article published on March 1995

Prostacyclin in pregnancy

scientific article published on 01 December 1984

Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure

scientific article

Prostacyclin production in whole blood throughout normal pregnancy

article

Protective effect of vitamin E on immune triggered, granulocyte mediated endothelial injury

scientific article published on 01 February 1984

Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4.

scientific article published in November 2006

Recirculated normal platelets adhere to surfaces coated with plasma from patients with immune thrombocytopenia.

scientific article

Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease

scientific article

Reorientation of prostaglandin endoperoxide metabolism by a thromboxane synthetase inhibitor: in vitro and clinical observations.

scientific article

Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease

scientific article

Role of glycoprotein Ib? in phagocytosis of platelets by macrophages

scientific article published on 01 December 2006

Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism

scientific article published on November 1987

Roles of Src-like adaptor protein 2 (SLAP-2) in GPVI-mediated platelet activation SLAP-2 and GPVI signaling

scientific article published on 15 September 2010

Selection of phages that inhibit vWF interaction with collagen under both static and flow conditions.

scientific article

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer

scientific article published on 11 September 2020

Sequence alignment between vWF and peptides inhibiting the vWF-collagen interaction does not result in the identification of a collagen-binding site in vWF

scientific article published on 01 October 2000

Serum albumin enhances the impairment of platelet aggregation with thromboxane synthase inhibition by increasing the formation of prostaglandin D2.

scientific article published on July 1984

Shear-dependent morphology of von Willebrand factor bound to immobilized collagen

scientific article published on 01 March 2002

Shielding of the A1 domain by the D'D3 domains of von Willebrand factor modulates its interaction with platelet glycoprotein Ib-IX-V.

scientific article

Signal transduction in blood platelets

scientific article published on January 1, 1991

Single particle tracking of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type-1 repeats) molecules on endothelial von Willebrand factor strings

scientific article

Sodium fluoride induced activation of phospholipase C in intact human platelets does not depend on ADP, PAF or arachidonate products

scientific article published on 01 March 1993

Sodium fluoride mimics effects of both agonists and antagonists on intact human platelets by simultaneous modulation of phospholipase C and adenylate cyclase activity

scientific article published on 01 March 1987

Stabilization of beta-lactoglobulin in alkaline medium by 2-p-toluidinylnaphthalene-6-sulphonate [proceedings]

scientific article published on May 1979

Structural determinants within platelet glycoprotein Ibalpha involved in its binding to von Willebrand factor.

scientific article

Synergistic antiplatelet effect of ridogrel, a combined thromboxane receptor antagonist and thromboxane synthase inhibitor, and UDCG-212, a cAMP-phosphodiesterase inhibitor

scientific article published on 01 November 1993

Synergistic effect of thrombin on collagen-induced platelet procoagulant activity is mediated through protease-activated receptor-1.

scientific article published on 21 April 2005

The A/T1381 polymorphism in the A1-domain of von Willebrand factor influences the affinity of von Willebrand factor for platelet glycoprotein Ibalpha

scientific article

The CX3C chemokine fractalkine mediates platelet adhesion via the von Willebrand receptor glycoprotein Ib.

scientific article published on 11 March 2011

The GPIbalpha-thrombin interaction: far from crystal clear.

scientific article published on January 2004

The collagen-binding leech products rLAPP and calin prevent both von Willebrand factor and alpha2beta1(GPIa/IIa)-I-domain binding to collagen in a different manner

scientific article published on 01 September 1999

The distal carboxyterminal domains of murine ADAMTS13 influence proteolysis of platelet-decorated VWF strings in vivo.

scientific article published on October 2010

The effect of plasmin on platelet function

scientific article published on 01 January 1996

The effect of sulphinpyrazone on whole blood thromboxane and prostacyclin generation in man

scientific article published on 01 October 1982

The humanized anti-glycoprotein Ib monoclonal antibody h6B4-Fab is a potent and safe antithrombotic in a high shear arterial thrombosis model in baboons.

scientific article

The integrin alpha 2 beta 1 (GPIa/IIa)-I-domain inhibits platelet-collagen interaction

scientific article published on 01 May 1997

The metabolism of phosphoinositide-derived messenger molecules.

scientific article

The novel ADAMTS13-p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice

scientific article

The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation

scientific article published on 27 March 2009

The parasitic hematophagous worm Haemonchus contortus inhibits human platelet aggregation and adhesion: partial purification of a platelet inhibitor.

scientific article published in May 2002

The platelet insulin receptor: Detection, partial characterization, and search for a function

scientific article published on 01 December 1988

The role of phosphoinositides in cell physiology

scientific article published on January 1986

The role of platelet and endothelial GARP in thrombosis and hemostasis

scientific article

The von Willebrand factor self-association is modulated by a multiple domain interaction

scientific article published on 01 March 2005

Thromboembolic complications and haemostatic changes in cyclosporin-treated cadaveric kidney allograft recipients

scientific article published on May 1985

Thrombosis and immune disorders

scientific article published on May 1986

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus).

scientific article

Thromboxane synthase inhibition combined with thromboxane receptor blockade: a step forward in antithrombotic strategy?

scientific article published on 01 December 1984

Thromboxane synthase inhibitors, thromboxane receptor antagonists and dual blockers in thrombotic disorders

scientific article

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

scientific article

Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type

scientific article published on 15 August 2005

Type 2B von Willebrand disease in seven individuals from three different families: phenotypic and genotypic characterization.

scientific article

Von Willebrand factor: drug and drug target.

scientific article published on March 2009

[Inhibition of integrin function prevents restenosis following vascular injury]

scientific article published on 01 September 1995

von Willebrand factor antigen latex immunoassays are affected to a different extent by rheumatoid factor

scientific article published in April 2006

von Willebrand factor binds to native collagen VI primarily via its A1 domain

scientific article published on May 1997

von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism

scientific article published on 29 May 2003

von Willebrand factor in experimental malaria-associated acute respiratory distress syndrome

scientific article published on 12 June 2019

von Willebrand factor to the rescue.

scientific article published on 24 March 2009

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