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List of works by Ana S. Coroadinha

A methodology for detection and quantification of esterase activity

scientific article published in January 2013

A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.

scientific article published on 11 May 2006

Adaptation of retrovirus producer cells to serum deprivation: Implications in lipid biosynthesis and vector production

scientific article

Bioprocess development for canine adenovirus type 2 vectors.

scientific article published on 5 July 2012

Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation.

scientific article published on 16 March 2015

Carboxylesterase 2 production and characterization in human cells: new insights into enzyme oligomerization and activity

scientific article

Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production

scientific article published on 25 August 2020

Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells

scientific article

Detection and Quantification of Carboxylesterase 2 Activity by Capillary Electrophoresis ⬇️

scientific article published on 05 January 2011

Disclosing the Parameters Leading to High Productivity of Retroviral Producer Cells Lines: Evaluating Random Versus Targeted Integration.

scientific article published on 16 March 2017

Down-regulation of CD81 in human cells producing HCV-E1/E2 retroVLPs

scientific article

Down-regulation of CD81 tetraspanin in human cells producing retroviral-based particles: tailoring vector composition.

scientific article published on 21 June 2011

Downstream Processing of Lentiviral Vectors: Releasing Bottlenecks ⬇️

scientific article published on August 30, 2012

Effect of medium sugar source on the production of retroviral vectors for gene therapy.

scientific article published on May 2006

Effect of osmotic pressure on the production of retroviral vectors: Enhancement in vector stability.

scientific article published on June 2006

Enhancing Hepatitis C virus pseudoparticles infectivity through p7NS2 cellular expression

scientific article published on 11 August 2019

Establishing Suspension Cell Cultures for Improved Manufacturing of Oncolytic Adenovirus

scientific article published on 27 January 2020

Evaluation of AAV-mediated delivery of shRNA to target basal-like breast cancer genetic vulnerabilities

scientific article published on 28 May 2019

Evaluation of Structurally Distorted Split GFP Fluorescent Sensors for Cell-Based Detection of Viral Proteolytic Activity

scientific article published on 23 December 2020

Flexible pseudotyping of retrovirus using recombinase-mediated cassette exchange

scientific article published on 20 January 2018

Flipase-mediated cassette exchange in Sf9 insect cells for stable gene expression

scientific article published on 19 May 2012

Human carboxylesterase 2: Studies on the role of glycosylation for enzymatic activity.

scientific article published on 19 November 2015

Impact of E1 and Cre on adenovirus vector amplification: developing MDCK CAV-2-E1 and E1-Cre transcomplementing cell lines.

scientific article

Impact of adenovirus life cycle progression on the generation of canine helper-dependent vectors.

scientific article

Impact of retroviral vector components stoichiometry on packaging cell lines: effects on productivity and vector quality

scientific article published on February 2008

Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes

scientific article published on 14 August 2019

Improving retroviral vectors production: role of carbon sources in lipid biosynthesis

scientific article published on 27 August 2008

Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK.

scientific article

Insect cell culture medium supplementation with fetal bovine serum and bovine serum albumin: effects on baculovirus adsorption and infection kinetics

scientific article published on July 2002

Insect cell line development using FLP-mediated cassette exchange technology

scientific article published on January 2014

Integrated strategy for the production of therapeutic retroviral vectors

scientific article published on 2 March 2011

Intracellular Delivery of HCV NS3p gene using vectored particles.

scientific article

LentiPro26: novel stable cell lines for constitutive lentiviral vector production.

scientific article

Manufacturing of retroviruses

scientific article published on January 2011

Metabolic flux profiling of MDCK cells during growth and canine adenovirus vector production

scientific article published on 23 March 2016

Metabolic pathways recruited in the production of a recombinant enveloped virus: mining targets for process and cell engineering

scientific article published on 11 October 2013

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1

scientific article published on 01 May 2018

Overexpression of ER Protein Processing and Apoptosis Regulator Genes in HEK 293 Cells Improves Gene Therapy Vectors Production

scientific article published on 08 July 2020

Palmitoylation Strengthens Cholesterol-dependent Multimerization and Fusion Activity of Human Cytomegalovirus Glycoprotein B (gB).

scientific article published on 22 December 2015

Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells

scientific article published on 21 May 2015

Production of retroviral vectors: review

scientific article published on December 2010

Progress and perspectives in the development of lentiviral vector producer cells

scientific article published on 20 July 2020

Pseudotyping retrovirus like particles vaccine candidates with Hepatitis C virus envelope protein E2 requires the cellular expression of CD81

scientific article published on 07 February 2019

Quantitation of MLV-based retroviral vectors using real-time RT-PCR.

scientific article

Relationship between retroviral vector membrane and vector stability

scientific article published on May 2006

Retroviral particles are effectively purified on an affinity matrix containing peptides selected by phage-display

scientific article

Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines.

scientific article published on August 2010

Retroviral vector production under serum deprivation: The role of lipids

scientific article

Retrovirus producer cell line metabolism: implications on viral productivity.

scientific article published on 6 April 2006

Robust Expansion of Human Pluripotent Stem Cells: Integration of Bioprocess Design With Transcriptomic and Metabolomic Characterization

scientific article published on 15 May 2015

Semliki Forest Virus replicon particles production in serum-free medium BHK-21 cell cultures and their use to express different proteins

scientific article published on 17 August 2019

Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells.

scientific article published on 4 May 2015

Small synthetic ligands for the enrichment of viral particles pseudotyped with amphotropic murine leukemia virus envelope.

scientific article

Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer

scientific article

Tetraspanins displayed in retrovirus-derived virus-like particles and their immunogenicity.

scientific article published on 12 January 2016

The use of recombinase mediated cassette exchange in retroviral vector producer cell lines: predictability and efficiency by transgene exchange

scientific article published on 9 March 2006

Thermosensitivity of the reverse transcription process as an inactivation mechanism of lentiviral vectors

scientific article published on October 2009

Tryptophan tags and de novo designed complementary affinity ligands for the expression and purification of recombinant proteins

scientific article

Upstream Bioprocess for Adenovirus Vectors

Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

scientific article published on 24 July 2015

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