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List of works by Sunil Laxman

A minimal "push-pull" bistability model explains oscillations between quiescent and proliferative cell states

scientific article published on 25 July 2018

A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis

scientific article published on 01 July 2019

A versatile LC-MS/MS approach for comprehensive, quantitative analysis of central metabolic pathways

scientific article published on 20 September 2018

Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria

scientific article published on 03 January 2020

Behavior of a metabolic cycling population at the single cell level as visualized by fluorescent gene expression reporters

scientific article

Characterization of a novel cAMP-binding, cAMP-specific cyclic nucleotide phosphodiesterase (TcrPDEB1) from Trypanosoma cruzi

scientific article

Conceptualizing Eukaryotic Metabolic Sensing and Signaling

scientific article published on 22 March 2017

Concerted effort: oscillations in global gene expression during nematode development

scientific article published in February 2014

Correction: Metabolic constraints drive self-organization of specialized cell groups

scientific article published on 17 December 2020

Correction: Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community

scientific article published in 2021

Cyclic nucleotide signaling mechanisms in trypanosomes: possible targets for therapeutic agents.

scientific article published on August 2007

Cyclic nucleotide specific phosphodiesterases of the kinetoplastida: a unified nomenclature.

scientific article published on 21 October 2005

Decoding the stem cell quiescence cycle--lessons from yeast for regenerative biology

scientific article

Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program

scientific article published on 30 December 2020

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

scholarly article

Metabolic constraints drive self-organization of specialized cell groups

scientific article published on 26 June 2019

Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR

scientific article published on 16 March 2016

Methionine at the Heart of Anabolism and Signaling: Perspectives From Budding Yeast

scientific article published on 15 November 2019

Methionine coordinates a hierarchically organized anabolic program enabling proliferation

article

Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2A

scientific article

Methionine is a signal of amino acid sufficiency that inhibits autophagy through the methylation of PP2A.

scientific article published on 18 December 2013

Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program

scientific article published on 29 October 2020

Multiple TORC1-associated proteins regulate nitrogen starvation-dependent cellular differentiation in Saccharomyces cerevisiae.

scientific article

Npr2 inhibits TORC1 to prevent inappropriate utilization of glutamine for biosynthesis of nitrogen-containing metabolites

scientific article published on 16 December 2014

Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2

scientific article published on 9 July 2015

Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community

scientific article published on 02 September 2020

Steady-state and Flux-based Trehalose Estimation as an Indicator of Carbon Flow from Gluconeogenesis or Glycolysis

scientific article published on 01 January 2020

Sulfur amino acids regulate translational capacity and metabolic homeostasis through modulation of tRNA thiolation

scientific article published on July 2013

Systems approaches for the study of metabolic cycles in yeast

scientific article

The E3 ubiquitin ligase Pib1 regulates effective gluconeogenic shutdown upon glucose availability

scientific article published on 11 October 2019

The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing

scientific article published on 19 August 2020

The glyoxylate shunt is essential for desiccation tolerance in C. elegans and budding yeast

scientific article (publication date: 19 April 2016)

Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

scientific article published on 27 March 2017

Trypanosome cyclic nucleotide phosphodiesterase 2B binds cAMP through its GAF-A domain

scientific article

cAMP Signaling and Regulation by Phosphodiesterases in Trypanosomes ⬇️

doctoral thesis by Sunil Laxman, 2006

tRNA wobble-uridine modifications as amino acid sensors and regulators of cellular metabolic state

scientific article published on 22 November 2019

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