Search filters

List of works by Anthony Howell

A New Hormonal Therapy for Prostatic Cancer: Long-term Clinical and Hormonal Response

scientific article published on 01 October 1986

A Phase II study of docetaxel in patients with liver metastases from breast cancer

scientific article published on 01 May 2000

A cancer research (UK) randomized phase II study of idoxifene in patients with locally advanced/metastatic breast cancer resistant to tamoxifen.

scientific article

A case-control evaluation of 143 single nucleotide polymorphisms for breast cancer risk stratification with classical factors and mammographic density

scientific article published on 13 July 2019

A comparison of five methods of measuring mammographic density: a case-control study

scientific article published on 5 February 2018

A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast ⬇️

scientific article published on July 1, 1984

A controlled trial of adjuvant tamoxifen, with or without prednisolone, in post-menopausal women with operable breast cancer.

scientific article

A follow-up study of breast and other cancers in families of an unselected series of breast cancer patients

scientific article published on March 2002

A lower incidence of gynecologic adverse events and interventions with anastrozole than with tamoxifen in the ATAC trial

scientific article published on 18 November 2008

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

scientific article published on 16 January 2020

A novel continuous infusional 5-fluorouracil-based chemotherapy regimen compared with conventional chemotherapy in the neo-adjuvant treatment of early breast cancer: 5 year results of the TOPIC trial

scientific article published in May 2004

A phase I toxicity study of human rDNA interferon in patients with solid tumours

article

A phase II study of oral weekly 4-demethoxydaunorubicin in advanced breast cancer.

scientific article

A protocol for preventative mastectomy in women with an increased lifetime risk of breast cancer

scientific article published on 01 November 2000

A radiation-controlled molecular switch for use in gene therapy of cancer.

scientific article published in July 2000

A randomised study to compare the effect of the luteinising hormone releasing hormone (LHRH) analogue goserelin with or without tamoxifen in pre- and perimenopausal patients with advanced breast cancer

scientific article published on 01 January 1995

A randomised trial comparing two doses of the new selective aromatase inhibitor anastrozole (Arimidex) with megestrol acetate in postmenopausal patients with advanced breast cancer.

scientific article

A randomised trial of screening with digital breast tomosynthesis plus conventional digital 2D mammography versus 2D mammography alone in younger higher risk women

scientific article published on 30 June 2017

A randomized comparison of tamoxifen with surgical oophorectomy in premenopausal patients with advanced breast cancer

scientific article published on 01 September 1986

A review of the efficacy of anastrozole in postmenopausal women with advanced breast cancer with visceral metastases.

scientific article published on December 2003

A roundtable discussion of aromatase inhibitors as therapy for breast cancer.

scientific article

A single-blind, randomised, vehicle-controlled dose-finding study of recombinant human granulocyte colony-stimulating factor (lenograstim) in patients undergoing chemotherapy for solid cancers and lymphoma

scientific article published on 01 December 1995

ARIMIDEX: a potent and selective aromatase inhibitor for the treatment of advanced breast cancer

scientific article published on April 1997

Absence of sulphation factor (somatomedin) activity in preparations of colony stimulating factor and nerve growth factor

scientific article published on 01 October 1974

Abstract PD1-07: Mammographic density and SNPs add to Tyrer-Cuzick and Gail model breast cancer risk in a UK screening cohort

Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine

scientific article published on July 2011

Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study

scientific article published in June 2002

Acute chemotherapy-related toxicity is not increased in BRCA1 and BRCA2 mutation carriers treated for breast cancer in the United Kingdom

scientific article published in December 2006

Addition of pathology and biomarker information significantly improves the performance of the Manchester scoring system for BRCA1 and BRCA2 testing

article

Adjuvant aromatase inhibitors for breast cancer

scientific article published in August 2005

Adjuvant chemotherapy in early breast cancer

scientific article

Adjuvant cyclophosphamide, methotrexate, and fluorouracil in patients with axillary node-positive breast cancer: an update of the Guy's/Manchester trial

scientific article published on 01 December 1990

Adjuvant docetaxel for node-positive breast cancer

scientific article published in June 2005

Adjuvant use of anastrozole in breast cancer

scientific article published in April 2004

Adult weight gain and central obesity in women with and without a family history of breast cancer: a case control study

scientific article

Allelic imbalance on chromosome I in human breast cancer. II. Microsatellite repeat analysis

article

An evaluation of common breast cancer gene mutations in a population of Ashkenazi Jews ⬇️

scientific article published on January 1, 1998

An open randomised trial of second-line endocrine therapy in advanced breast cancer: comparison of the Aromatase inhibitors letrozole and anastrozole

scientific article

Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety upda

scientific article published in November 2003

Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial

scientific article published on 11 December 2015

Anastrozole-Induced Carpal Tunnel Syndrome: Results From the International Breast Cancer Intervention Study II Prevention Trial

scientific article published on 23 November 2015

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

scientific article

Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

scientific article published on 15 November 2011

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease

scientific article published on March 2015

Are BRCA1- and BRCA2-related breast cancers associated with increased mortality?

scientific article

Are We Ready for Online Tools in Decision Making for BRCA1/2 Mutation Carriers? ⬇️

scientific article published on January 9, 2012

Are aromatase inhibitors superior to antiestrogens?

scientific article

Assessing individual breast cancer risk within the U.K. National Health Service Breast Screening Program: a new paradigm for cancer prevention

scientific article

Assessment of Hormone Dependence of Comedo Ductal Carcinoma In Situ of the Breast

scientific article published on 01 July 1997

Assessment of four monoclonal antibodies as serum markers in breast cancer

scientific article published on 01 January 1990

Assessment of renal function during high-dose cis-platinum therapy in patients with ovarian carcinoma

scientific article published on 01 January 1982

Assessment of tumour vascularity as a prognostic factor in lymph node negative invasive breast cancer

article

Association of gain and loss of weight before and after menopause with risk of postmenopausal breast cancer in the Iowa women's health study

scientific article published in March 2005

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

scientific article published on 18 August 2021

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production

scientific article

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

scientific article

BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies

scientific article published on 21 November 2012

BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives

article published in 2006

Bayesian evaluation of breast cancer screening using data from two studies

scientific article

Beliefs about weight and breast cancer: an interview study with high risk women following a 12 month weight loss intervention ⬇️

scientific article

Better life expectancy in women with BRCA2 compared with BRCA1 mutations is attributable to lower frequency and later onset of ovarian cancer

scientific article published in June 2008

Biomarkers of dietary energy restriction in women at increased risk of breast cancer.

scientific article

Birmingham Medical Research Expeditionary Society 1977 Expedition: the diuresis and related changes during a trek to high altitude

scientific article published on July 1979

Breakthroughs in research and treatment of early breast cancer: an overview of the last three decades

scientific article

Breast Cancer Risk for Noncarriers of Family-SpecificBRCA1andBRCA2Mutations: More Trouble With Phenocopies

scientific article published on 27 February 2012

Breast cancer pathology and stage are better predicted by risk stratification models that include mammographic density and common genetic variants

scientific article

Breast cancer prevention: SERMs come of age.

scientific article published on 30 April 2013

Breast cancer risk assessment in 8,824 women attending a family history evaluation and screening programme

scientific article published on 01 June 2014

Breast cancer risk feedback to women in the UK NHS breast screening population.

scientific article published on 29 March 2016

Breast cancer risk in a screening cohort of Asian and white British/Irish women from Manchester UK.

scientific article published on 25 January 2018

Breast cancer risk in young women in the national breast screening programme: implications for applying NICE guidelines for additional screening and chemoprevention

scientific article published on 21 July 2014

Breast cancer risk status influences uptake, retention and efficacy of a weight loss programme amongst breast cancer screening attendees: two randomised controlled feasibility trials

scientific article published on 04 December 2019

Breast cancer risk-assessment models

scientific article

Breast cancer susceptibility variants alter risk in familial ovarian cancer

scientific article published in December 2010

Breast cancer susceptibility variants alter risks in familial disease.

scientific article

Breast cancer, desmold tumours, and familial adenomatous polyposis

scientific article published in The Lancet

Breast cancer: aromatase inhibitors take on tamoxifen

scientific article published in December 2002

Breast cancer: oncogenes and suppressor genes

article

Breast density and breast cancer risk factors in a high-risk population.

scientific article

Breast tumour stroma is a prognostic indicator and target for therapy

scientific article

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis

scientific article

CONTROLLED TRIAL OF ADJUVANT CHEMOTHERAPY WITH CYCLOPHOSPHAMIDE, METHOTREXATE, AND FLUOROURACIL FOR BREAST CANCER

scientific article published in The Lancet

CONTROLLED TRIAL OF ADJUVANT CHEMOTHERAPY WITH MELPHALAN FOR BREAST CANCER

scientific article published in The Lancet

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.

scientific article

Can diet and lifestyle prevent breast cancer: what is the evidence?

scientific article

Can metabolomics in addition to genomics add to prognostic and predictive information in breast cancer? ⬇️

scientific article published on November 16, 2010

Can multiple SNP testing in BRCA2 and BRCA1 female carriers be used to improve risk prediction models in conjunction with clinical assessment?

scientific article

Can the breast screening appointment be used to provide risk assessment and prevention advice?

scientific article published on 9 July 2015

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors

scientific article

Cancer experience in the relatives of an unselected series of breast cancer patients.

scientific article

Cancer genetics clinics

article

Carbonic anhydrase 9 (CA9) and redox signaling in cancer-associated fibroblasts: therapeutic implications

scientific article published on 30 July 2013

Case report: pleural encasement secondary to acinar adenocarcinoma of the submandibular gland.

scientific article published on March 1996

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

scientific article

Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts

scientific article

Cellular aspects of breast cancer: workshop report

scientific article published on January 1988

Central obesity and breast cancer risk: a systematic review.

scientific article

Changes in bone mineral density at 3 years in postmenopausal women receiving anastrozole and risedronate in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial

scientific article published on 11 November 2014

Changes in the extracellular matrix of the normal human breast during the menstrual cycle

scientific article published in April 1992

Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.

scientific article published on 6 February 2013

Cisplatin in patients with a non-functioning kidney

scientific article published on 01 August 1981

Citrobacter freundii and fatal neutropenic enterocolitis following adjuvant chemotherapy for breast cancer

scientific article published on January 1997

Clarification of Anastrozole/Megestrol Acetate Trial Program Design

scientific article published on 01 December 2000

Clinical development of fulvestrant ("Faslodex").

scientific article

Clinical effects of human macrophage inflammatory protein-1 alpha MIP-1α (LD78) administration to humans: a phase I study in cancer patients and normal healthy volunteers with the genetically engineered variant, BB-10010

scientific article published on 01 June 1998

Clinical pharmacology of oral and intravenous 4-demethoxydaunorubicin

scientific article published on 01 January 1987

Comment on progesterone effects in breast tissue

scientific article published on 01 October 1987

Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer

scientific article published on 01 January 1990

Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial

scientific article published in May 2004

Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy

scientific article published on September 2010

Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety analysis of the ATAC trial

article

Consensus statement. Workshop on therapeutic resistance in breast cancer: impact of growth factor signalling pathways and implications for future treatment.

scientific article

Contraceptive use by women receiving chemotherapy for breast cancer

Contralateral breast cancer risk in BRCA1/2-positive families needs to be adjusted for phenocopy rates particularly in second-degree untested relatives

scientific article published on 26 February 2013

Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer

scientific article published on 20 June 2013

Could Intermittent Energy Restriction and Intermittent Fasting Reduce Rates of Cancer in Obese, Overweight, and Normal-Weight Subjects? A Summary of Evidence

scientific article published on 15 July 2016

Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo.

scientific article published on February 2012

Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model

scientific article

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Cyclin-dependent kinase inhibitors and basement membrane interact to regulate breast epithelial cell differentiation and acinar morphogenesis.

scientific article

Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator

scientific article

DNA analysis by flow cytometry, response to endocrine treatment and prognosis in advanced carcinoma of the breast.

scientific article

Defining bad stroma in human breast tumors ⬇️

scientific article published on September 15, 2011

Depression of bone marrow colony formation in gold-induced neutropenia ⬇️

scientific article published on February 22, 1975

Detection and management of women at increased risk of breast cancer

Dibromodulcitol, mitomycin C and vinblastine (DMV) chemotherapy in advanced breast cancer.

scientific article

Do women understand the odds? Risk perceptions and recall of risk information in women with a family history of breast cancer

scientific article published in January 2003

Does HER2 overexpression affect response to endocrine therapy in advanced cancer?

scientific article published on 01 February 2006

Does hormone therapy for the treatment of breast cancer have a detrimental effect on memory and cognition? A pilot study

scientific article published in January 2004

Does the prediction of breast cancer improve using a combination of mammographic density measures compared to individual measures alone?

Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1α, autophagy and ketone body production

scientific article

Doxorubicin in advanced breast cancer: influence of schedule on response, survival and quality of life

scientific article published in January 1992

Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II. ⬇️

scientific article published on 6 November 2017

Early stopping of clinical trials

scientific article

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

scientific article published on 17 November 2010

Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230.

scientific article

Effect of baseline serum vitamin D levels on aromatase inhibitors induced musculoskeletal symptoms: results from the IBIS-II, chemoprevention study using anastrozole

scientific article published on 25 December 2011

Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial

scientific article published on 14 June 2010

Effect of clothing on dispersal of Staphylococcus aureus by males and females.

scientific article

Effect of early American results on patients in a tamoxifen prevention trial (IBIS)

scientific article published in The Lancet

Effect of inhalation anaesthetics on division of bone-marrow cells in vitro ⬇️

scientific article published on February 1, 1976

Effect of sodium butyrate on synthesis of specific proteins by human breast-carcinoma cells.

scientific article published on October 1980

Effect of tamoxifen on Ki67 labelling index in human breast tumours and its relationship to oestrogen and progesterone receptor status.

scientific article

Effect of tamoxifen upon cell DNA analysis by flow cytometry in primary carcinoma of the breast

scientific article

Effects of 4-hydroxytamoxifen and a novel pure antioestrogen (ICI 182780) on the clonogenic growth of human breast cancer cells in vitro.

scientific article

Effects of anastrozole on cognitive performance in postmenopausal women: a randomised, double-blind chemoprevention trial (IBIS II).

scientific article published on September 2008

Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue

scientific article published in June 2006

Effects of oestrogens and anti-oestrogens on normal breast tissue from women bearing BRCA1 and BRCA2 mutations.

scientific article published on April 2006

Effects of short-term antiestrogen treatment of primary breast cancer on estrogen receptor mRNA and protein expression and on estrogen-regulated genes

article

Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast

scientific article published on 01 December 1998

Endometrial cancer and venous thromboembolism in women under age 50 who take tamoxifen for prevention of breast cancer: a systematic review.

scientific article

Energy Balance in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy

scientific article published on 01 February 2004

Energy balance in patients with advanced NSCLC, metastatic melanoma and metastatic breast cancer receiving chemotherapy--a longitudinal study.

scientific article published on February 2005

Energy restriction and the prevention of breast cancer

scientific article published on 14 March 2012

Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells

scientific article

Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation

scientific article

Estrogen Receptor Expression in 21-Gene Recurrence Score Predicts Increased Late Recurrence for Estrogen-Positive/HER2-Negative Breast Cancer

scientific article published on June 2015

Estrogen responsiveness and control of normal human breast proliferation.

scientific article

Estrogen sensitivity of normal human breast tissue in vivo and implanted into athymic nude mice: analysis of the relationship between estrogen-induced proliferation and progesterone receptor expression

scientific article published on September 1997

Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention

scientific article (publication date: 15 January 2013)

Evaluation of the current knowledge limitations in breast cancer research: a gap analysis

scientific article published on 27 March 2008

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

scientific article

Expression of activated gelatinase in human invasive breast carcinoma

scientific article published on 01 March 1993

Expression of differentiation antigens within human mammary tumours is related to response to endocrine therapy and survival

scientific article published on 01 August 1988

Extended role for needle biopsy in the management of carcinoma of the breast

scientific article published on 01 June 1989

FIBROBLASTS FROM RELATIVES OF PATIENTS WITH HEREDITARY BREAST CANCER SHOW FETAL-LIKE BEHAVIOUR IN VITRO

scientific article published in The Lancet

False-negative MRI breast screening in high-risk women.

scientific article published on 5 December 2016

Familial breast cancer.

scientific article published on January 1994

Final Results of the Prospective FH02 Mammographic Surveillance Study of Women Aged 35-39 at Increased Familial Risk of Breast Cancer

scientific article published on 01 January 2019

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Fulvestrant ('Faslodex'): current and future role in breast cancer management.

scientific article

Fulvestrant (Faslodex): current status in the therapy of breast cancer.

scientific article

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, mult

scientific article published on 29 July 2013

Fulvestrant revisited: efficacy and safety of the 500-mg dose

scientific article published on 04 May 2011

Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women: a prospective combined analysis of two multicenter trials

scientific article published in July 2003

Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined survival analysis of two multicenter trials

scientific article published in July 2005

Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment

scientific article published in August 2002

Genesis and Outcome of a Breast Cancer Trial to Develop the Aromatase Inhibitor Anastrozole

scientific article published on 14 February 2012

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance

scientific article published on 15 December 2011

Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling

scientific article published on 15 June 2010

Guidance for the management of breast cancer treatment-induced bone loss: a consensus position statement from a UK Expert Group.

scientific article published on 02 June 2008

HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

scientific article

HISTOLOGICAL DETECTION OF ŒSTROGEN RECEPTOR IN HUMAN BREAST CARCINOMAS

scientific article published in The Lancet

Haemopoietic cells mobilised into the circulation by lenograstim as alternative to bone marrow for allogeneic transplants

scientific article published in The Lancet

Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma

scientific article

High dose chemotherapy and autologous stem cell transplantation as adjuvant therapy for primary breast cancer patients with four or more lymph nodes involved: long-term results of an international randomised trial

scientific article published on 7 April 2005

High dose, dose-intensive chemotherapy with doxorubicin and cyclophosphamide for the treatment of advanced breast cancer ⬇️

scientific article published on April 1, 1993

High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy

scientific article published in May 2001

High-throughput genomic technology in research and clinical management of breast cancer. Exploiting the potential of gene expression profiling: is it ready for the clinic?

scientific article published on January 2006

Hormonally-regulated proteins in breast secretions are markers of target organ sensitivity

scientific article published on January 2000

Hormone replacement therapy and breast cancer

How to Manage the Obese Patient With Cancer

scientific article published on 7 November 2016

Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".

scientific article

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue

scientific article published on December 2011

Idarubicin and cyclophosphamide--an active oral chemotherapy regimen for advanced breast cancer

scientific article

Immunohistochemical BAG1 expression improves the estimation of residual risk by IHC4 in postmenopausal patients treated with anastrazole or tamoxifen: a TransATAC study.

scientific article published on 13 July 2013

Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

scientific article published on 28 December 2016

Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer.

scientific article published in August 2004

Increased rate of phenocopies in all age groups in BRCA1/BRCA2 mutation kindred, but increased prospective breast cancer risk is confined to BRCA2 mutation carriers

scientific article

Increasing growth with raised circulating somatomedin but normal immunoassayable growth hormone

scientific article published on June 1, 1977

Indices of differential endometrial : myometrial growth may be used to improve the reliability of detecting endometrial neoplasia in women on tamoxifen

scientific article published on 01 December 1996

Infiltrating lobular carcinoma of the breast: Response to endocrine therapy and survival

article

Influence of Comorbidities and Age on Risk of Death Without Recurrence: A Retrospective Analysis of the Arimidex, Tamoxifen Alone or in Combination Trial

article

Infusion rate and pharmacokinetics of intravenous pamidronate in the treatment of tumour-induced hypercalcaemia ⬇️

scientific article published on June 1, 1992

Insights into the place of fulvestrant for the treatment of advanced endocrine responsive breast cancer

scientific article published on 20 September 2010

Intensive breast screening in BRCA2 mutation carriers is associated with reduced breast cancer specific and all cause mortality.

scientific article published on 14 April 2016

Intermittent energy restriction for weight loss: Spontaneous reduction of energy intake on unrestricted days.

scientific article

Intermittent energy restriction induces changes in breast gene expression and systemic metabolism

scientific article published on 28 May 2016

Intravascular haemolysis and renal impairment after blood transfusion in two patients on long-term 5-fluorouracil and mitomycin-C ⬇️

scientific article published on June 14, 1980

Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism

scientific article published on 15 January 2012

Is fulvestrant ("Faslodex") just another selective estrogen receptor modulator?

scientific article published on September 2006

JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.

scientific article published on 05 December 2013

Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells

scientific article

Ketone body utilization drives tumor growth and metastasis

scientific article

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

scientific article

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

scientific article

Lack of caveolin-1 (P132L) somatic mutations in breast cancer

article

Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom.

scientific article published in December 2006

Lifestyle behaviours and health measures of women at increased risk of breast cancer taking chemoprevention

article

Liposomal drug delivery

scientific article published on September 1996

Lobular carcinoma of the breast can be managed by breast-conserving therapy

scientific article published on October 1995

Local mammographic density as a predictor of breast cancer

Long-term effects of anastrozole on bone mineral density: 7-year results from the ATAC trial

scientific article published on 7 October 2010

Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial

scientific article published in October 2003

Long-term outcomes of breast cancer in women aged 30 years or younger, based on family history, pathology and BRCA1/BRCA2/TP53 status

scientific article

Long-term prospective clinical follow-up after BRCA1/2 presymptomatic testing: BRCA2 risks higher than in adjusted retrospective studies

scientific article

Long-term results of tamoxifen prophylaxis for breast cancer--96-month follow-up of the randomized IBIS-I trial

scientific article

Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women

scientific article

Low prevalence of HER2 positivity amongst BRCA1 and BRCA2 mutation carriers and in primary BRCA screens

scientific article

Lung cancer after treatment for Hodgkin's lymphoma: a systematic review

scientific article

Lung cancer after treatment for breast cancer

scientific article published on 10 June 2010

MRI breast screening in high-risk women: cancer detection and survival analysis

scientific article

Magnetic resonance imaging of bone metastases: A diagnostic and screening technique

scientific article published on 01 August 1997

Mammographic Density Over Time in Women With and Without Breast Cancer

Mammographic breast density refines Tyrer-Cuzick estimates of breast cancer risk in high-risk women: findings from the placebo arm of the International Breast Cancer Intervention Study I.

scientific article

Mammographic density adds accuracy to both the Tyrer-Cuzick and Gail breast cancer risk models in a prospective UK screening cohort

scientific article

Mammographic surveillance in women aged 35-39 at enhanced familial risk of breast cancer (FH02).

scientific article

Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis

scientific article

Measurement of urinary collagen cross-links indicate response to therapy in patients with breast cancer and bone metastases.

scientific article published on June 1999

Mechanism of action of adjuvant chemotherapy in early breast cancer

scientific article published on August 1986

Mechanisms of Disease: prediction and prevention of breast cancer--cellular and molecular interactions

scientific article

Menopausal symptoms and bone health in women undertaking risk reducing bilateral salpingo-oophorectomy: significant bone health issues in those not taking HRT.

scientific article

Metabolic approaches to breast cancer treatment and prevention.

scientific article

Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth

scientific article

Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells

scientific article

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.

scientific article

Migration stimulating activity in serum of breast cancer patients

scientific article published in The Lancet

Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

scientific article published on 21 November 2012

Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance

scientific article

Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.

scientific article published on 20 December 2012

Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth

scientific article

Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue

scientific article

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection

scientific article published on December 2011

Mobilisation kinetics of primitive haemopoietic cells following G-CSF with or without chemotherapy for advanced breast cancer

scientific article published on 01 December 1996

Molecular expression of epitopes recognized by monoclonal antibodies HMFG-1 and HMFG-2 in human breast cancers: Diversity, variability and relationship to prognostic factors

scientific article published on 01 July 1986

Native and inducible levels of natural cytotoxicity in lymph nodes draining mammary carcinoma

scientific article published on 01 January 1983

New endocrine agents ⬇️

scientific article published on July 1, 1997

New endocrine therapies for breast cancer

scientific article published on April 1996

No strong evidence for increased risk of breast cancer 8-26 years after multiple mammograms in their 30s in females at moderate and high familial risk

scientific article published on 21 January 2016

No useful role for fine needle aspiration as a marker for familial breast cancer

scientific article published on 01 August 2000

Non-standard management of breast cancer increases with age in the UK: a population based cohort of women > or =65 years

scientific article published on 27 March 2007

Normal breast tissue implanted into athymic nude mice identifies biomarkers of the effects of human pregnancy levels of estrogen

scientific article published on 03 March 2009

O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts

scientific article published on November 2005

Occult Hyperparathyroidism Presenting as a Parathyroid Cyst ⬇️

scientific article published on October 1, 1972

Occurrence of a fetal fibroblast phenotype in familial breast cancer

scientific article published on 01 June 1986

Oestrogen and breast cancer: results from the WHI trial

scientific article published on 07 March 2012

Oestrogen and progesterone receptors in acoustic neuroma

scientific article published on 01 November 1990

Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.

scientific article published on 08 July 2013

Oral contraceptive (OCP) use increases proliferation and decreases oestrogen receptor content of epithelial cells in the normal human breast

article

Origins of breast cancer subtypes and therapeutic implications

scientific article published on September 2007

Ovarian cancer among 8,005 women from a breast cancer family history clinic: no increased risk of invasive ovarian cancer in families testing negative for BRCA1 and BRCA2.

scientific article published on 28 March 2013

Overcoming endocrine resistance in breast cancer: are signal transduction inhibitors the answer?

scientific article published on 22 May 2007

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

scientific article

Parathyroid hormone and parathyroid hormone-related protein in the investigation of hypercalcaemia in two hospital populations

scientific article published on 01 October 1994

Parathyroid hormone-related protein(50-69) and response to pamidronate therapy for tumour-induced hypercalcaemia.

scientific article published in January 1991

Participant-Reported Symptoms and Their Effect on Long-Term Adherence in the International Breast Cancer Intervention Study I (IBIS I). ⬇️

scientific article

Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

scientific article published on 17 March 2022

Pathology update to the Manchester Scoring System based on testing in over 4000 families.

scientific article published on 10 May 2017

Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting: risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

scientific article

Penetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing: a new unbiased method to assess risk?

scientific article published on 26 February 2018

Perception of risk in women with a family history of breast cancer

scientific article

Personalized prevention in high risk individuals: Managing hormones and beyond

scientific article published on 30 March 2018

Pharmacokinetic, biochemical and clinical effects of dimethyltriazenoimidazole-4-carboxamide-bischloroethylnitrosourea combination therapy in patients with advanced breast cancer

scientific article

Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex and tamoxifen alone or in combination' (ATAC) trial

scientific article

Pharmacokinetics of oral and intravenous fluorouracil in humans

article

Phase I/II evaluation of effervescent and enteric coated oral pamidronate for bone metastases

scientific article published on 01 January 1991

Phase II study of TCNU in advanced breast cancer

scientific article published on 01 August 1988

Phase III trial of epirubicin plus paclitaxel compared with epirubicin plus cyclophosphamide as first-line chemotherapy for metastatic breast cancer: United Kingdom National Cancer Research Institute trial AB01.

scientific article

Phenotypic heterogeneity in breast fibroblasts: Functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma

scientific article published on 01 October 1994

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients

scientific article published on 15 March 2012

Potential Benefits and Harms of Intermittent Energy Restriction and Intermittent Fasting Amongst Obese, Overweight and Normal Weight Subjects-A Narrative Review of Human and Animal Evidence.

scientific article published on 19 January 2017

Predicting compliance in a breast cancer prevention trial

scientific article published in September 2006

Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study

scientific article published on 8 March 2010

Predictive algorithms for adjuvant therapy: TransATAC.

scientific article published on 4 April 2011

Predictive classification of human breast carcinomas based on lactalbumin synthesis

scientific article

Preoperative endocrine therapy for breast cancer.

scientific article

Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancer

scientific article published on 07 June 2011

Preventing cancer, cardiovascular disease, and diabetes

scientific article published in The Lancet

Prevention of breast cancer in the context of a national breast screening programme

scientific article published on 01 April 2012

Preventive therapy for breast cancer: a consensus statement

scientific article published on May 2011

Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007.

scientific article published on January 2009

Proceedings: Bone marrow colony stimulating activity from the isolated perfused rat liver.

scientific article published in February 1974

Prognostic relevance of serum hyaluronan levels in patients with breast cancer

scientific article published on 01 December 1992

Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer

scientific article published on 11 October 2011

Prospective assessment of the role of five tumour markers in breast cancer

scientific article published on 01 January 1991

Psychological impact of providing women with personalised 10-year breast cancer risk estimates

article

Psychological support needs for women at high genetic risk of breast cancer: some preliminary indicators

scientific article published in September 1998

Psychosocial issues of a population approach to high genetic risk identification: Behavioural, emotional and informed choice issues.

scientific article published on 21 November 2017

Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth

scientific article

Quality of life of postmenopausal women in the ATAC ("Arimidex", tamoxifen, alone or in combination) trial after completion of 5 years' adjuvant treatment for early breast cancer

scientific article

Quality of life of postmenopausal women in the Arimidex, Tamoxifen, Alone or in Combination (ATAC) Adjuvant Breast Cancer Trial

scientific article published in November 2004

RASSF1A polymorphism in familial breast cancer

scientific article published in September 2010

RAZOR: A Phase II Open Randomized Trial of Screening Plus Goserelin and Raloxifene Versus Screening Alone in Premenopausal Women at Increased Risk of Breast Cancer

scientific article

Re: Tamoxifen for the Prevention of Breast Cancer: Current Status of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

scientific article published on 01 May 2006

Red clover isoflavones are safe and well tolerated in women with a family history of breast cancer

scientific article published in March 2008

Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast

article

Relationship of ZNF423 and CTSO with breast cancer risk in two randomised tamoxifen prevention trials.

scientific article published on 11 July 2016

Relationships between CYP2D6 phenotype, breast cancer and hot flushes in women at high risk of breast cancer receiving prophylactic tamoxifen: results from the IBIS-I trial.

scientific article

Release of Colony-Stimulating Activity from the Isolated Perfused Rat Liver

scientific article published on 01 June 1976

Response after withdrawal of tamoxifen and progestogens in advanced breast cancer ⬇️

scientific article published on 01 September 1992

Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer

scientific article published in The Lancet

Response to a specific antioestrogen (ICI 182780) in tamoxifen-resistant breast cancer.

scientific article published in April 1995

Response to intravenous bisphosphonate therapy in hypercalcaemic patients with and without bone metastases: the role of parathyroid hormone-related protein

scientific article

Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer.

scientific article

Retroperitoneal tumour infiltration detected by bone scanning in patients with infiltrating lobular carcinoma of the breast

scientific article published in August 1985

Reverse Warburg effect in a patient with aggressive B-cell lymphoma: is lactic acidosis a paraneoplastic syndrome?

scientific article

Review of recent trials of chemotherapy for advanced breast cancer: studies excluding taxanes

scientific article published on November 1997

Risk algorithms that include pathology adjustment for HER2 amplification need to make further downward adjustments in likelihood scores

scientific article published on 31 October 2016

Risk determination and prevention of breast cancer

scientific article

Risk factors. Introduction to Session 1

scientific article

Risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 30-year semi-prospective analysis

scientific article published on 4 August 2015

Risk of thyroid dysfunction during treatment with G-CSF

scientific article published in The Lancet

Risk reducing mastectomy: outcomes in 10 European centres.

scientific article published on 7 November 2008

Risk-reducing surgery increases survival in BRCA1/2 mutation carriers unaffected at time of family referral

scientific article published on 20 November 2013

Screening by mammography, women with a family history of breast cancer

scientific article published on 01 May 1998

Screening younger women with a family history of breast cancer – does early detection improve outcome?

scientific article published on 05 June 2006

Selective oestrogen receptor modulators, aromatase inhibitors and the female breast.

scientific article

Sensitivity to further endocrine therapy is retained following progression on first-line fulvestrant.

scientific article published in July 2005

Serum 1,25-Dihydroxyvitamin D May Be Related Inversely to Disease Activity in Breast Cancer Patients with Bone Metastases1

scientific article published on 01 January 1997

Serum Soluble Vascular Cell Adhesion Molecule-1: Role as a Surrogate Marker of Angiogenesis

scientific article published on 01 August 2000

Serum bioactive lactogenic hormone levels in women with familial breast cancer and their relatives.

scientific article published in December 1989

Serum immunoreactive and bioactive lactogenic hormones in advanced breast cancer patients treated with bromocriptine and octreotide

scientific article published on 01 January 1993

Serum proteins as tumour markers for breast cancer.

scientific article

Should We Adjust Visually Assessed Mammographic Density for Observer Variability?

Should aromatase inhibitors be used as initial adjuvant treatment or sequenced after tamoxifen?

scientific article

Should lifestyle modifications be promoted to prevent breast cancer?

scientific article published on 18 December 2008

Significant differences in UK and US female bone density reference ranges.

scientific article published on 9 January 2010

Single dose versus daily intravenous aminohydroxypropylidene biphosphonate (APD) for the hypercalcaemia of malignancy

scientific article published on March 1988

Spreading the word, but not too thinly

scientific article

Static disease on anastrozole provides similar benefit as objective response in patients with advanced breast cancer

article

Steroid-hormone receptors and survival after first relapse in breast cancer

scientific article

Stromal glycolysis and MCT4 are hallmarks of DCIS progression to invasive breast cancer

scientific article published on 27 August 2013

Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment

scientific article

Suramin for breast and prostate cancer: A pilot study of intermittent short infusions without adaptive control

scientific article published on 01 September 1994

Surgical decisions made by 158 women with hereditary breast cancer aged <50 years

scientific article published on 7 July 2005

Surveillance for familial breast cancer: Differences in outcome according toBRCA mutation status

scientific article published on 01 September 2007

Surveillance of women at increased risk of breast cancer using mammography and clinical breast examination: further evidence of benefit

scientific article published on 20 October 2011

Survival in prospectively ascertained familial breast cancer: Analysis of a series stratified by tumour characteristics,BRCAmutations and oophorectomy

article

TEXAS (Taxotere EXperience with Anthracyclines Study) trial: mature results of activity/toxicity of docetaxel given with anthracyclines in a community setting, as first line therapy for MBC.

scientific article

TPD52 and NFKB1 gene expression levels correlate with G2 chromosomal radiosensitivity in lymphocytes of women with and at risk of hereditary breast cancer

scientific article

TUMOUR INFORMATION FROM NEEDLE BIOPSY

scientific article published in The Lancet

Tamoxifen ("Nolvadex"): a review.

scientific article

Tamoxifen for prevention of breast cancer: extended long-term follow-up of the IBIS-I breast cancer prevention trial

scientific article published on 11 December 2014

Tamoxifen versus the newer SERMs: what is the evidence?

scientific article

Tamoxifen-Induced Reduction in Mammographic Density and Breast Cancer Risk Reduction: A Nested Case-Control Study

scientific article published on 11 April 2011

Targeting tumor-initiating cells: eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction

scientific article published on March 2015

Tenascin distribution in the normal human breast is altered during the menstrual cycle and in carcinoma

scientific article published on 01 February 1990

Testosterone and Gonadotrophin Profiles in Patients on Daily or Monthly LHRH Analogue ICI 118630 (Zoladex) Compared with Orchiectomy

scientific article published on 01 October 1986

The 'Arimidex', Tamoxifen, Alone or in Combination (ATAC) Trial: a step forward in the treatment of early breast cancer.

scientific article published on September 2006

The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services

scientific article

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The Relationship between Age and the Effect of Adjuvant Therapies in Women with Primary Breast Cancer

scientific article published on 01 January 1989

The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox

scientific article

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

scientific article

The clearance and bioavailability of pamidronate in patients with breast cancer and bone metastases

scientific article published on 01 December 1991

The clinical value of immunohistochemically demonstrable CEA in breast cancer: a possible method of selecting patients for adjuvant chemotherapy.

scientific article

The definition of the ‘no change’ category in patients treated with endocrine therapy and chemotherapy for advanced carcinoma of the breast

scientific article published on 01 October 1988

The diagnosis of the carrier state for the Lesch--Nyhan syndrome

scientific article published on April 1, 1975

The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women

scientific article

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

scientific article

The effects of oestrogens and anti-oestrogens on cognition

scientific article published on 01 December 2001

The effects of sex steroid replacement therapy on an expanded panel of IGF-related peptides

scientific article published on 13 March 2007

The emerging breast cancer epidemic: early diagnosis and treatment.

scientific article

The endocrine prevention of breast cancer

scientific article published on 01 August 2008

The expression of milk fat globule antigens within human mammary tumours: relationship to steroid hormone receptors and response to endocrine treatment

scientific article published on March 1989

The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study

scientific article

The impact of genetic counselling on risk perception in women with a family history of breast cancer

scientific article

The impact of using weight estimated from mammographic images vs. self-reported weight on breast cancer risk calculation

article

The kinetics of human granulopoiesis following treatment with granulocyte colony-stimulating factor in vivo.

scientific article

The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis

scientific article

The objective measurement of remission and progression in metastatic breast cancer by use of serum tumour markers

scientific article published on 01 January 1999

The origin of estrogen receptor alpha-positive and alpha-negative breast cancer

scientific article published on January 2008

The potential for proteinase inhibition in cancer treatment

scientific article

The prognostic significance of two epithelial membrane antigens expressed by human mammary carcinomas

scientific article published on 01 March 1984

The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone

scientific article published on 01 January 1995

The synthesis of the glycoprotein hormone alpha subunit by human breast carcinomas

scientific article published on May 1979

The value of dose intensification of standard chemotherapy for advanced breast cancer using colony-stimulating factors alone

scientific article published on 01 June 1998

The value of serial bone scanning in operable breast cancer

scientific article published on 01 June 1984

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

scientific article

Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial

scientific article published on 01 October 1997

Treatment of advanced prostatic cancer with LHRH analogue ICI 118630: clinical response and hormonal mechanisms

scientific article published on August 1983

Tropisetron compared with a metoclopramide-based regimen in the prevention of chemotherapy-induced nausea and vomiting

scientific article published on 01 January 1994

Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors

scientific article published on 15 June 2010

Tumour angiogenesis as a prognostic marker in infiltrating lobular carcinoma of the breast

scientific article published on 01 September 1996

Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography

scientific article published on 3 June 2015

Twenty-four hour combination chemotherapy: a feasibility study with implications for improved adjuvant treatment of breast cancer

scientific article published on 01 January 1983

Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells

scientific article

Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast

scientific article published on 01 November 1999

Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment

scientific article

Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

scientific article

Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells

scientific article

Uptake of breast cancer prevention and screening trials

scientific article published on 23 October 2010

Uptake of risk-reducing surgery in unaffected women at high risk of breast and ovarian cancer is risk, age, and time dependent

scientific article published in August 2009

Uptake of screening and prevention in women at very high risk of breast cancer

scientific article published in The Lancet

Uptake of tamoxifen in consecutive premenopausal women under surveillance in a high-risk breast cancer clinic.

scientific article published on 04 March 2014

Use of Single-Nucleotide Polymorphisms and Mammographic Density Plus Classic Risk Factors for Breast Cancer Risk Prediction

scientific article published on 18 January 2018

Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial

scientific article published on 12 December 2019

Variation of receptor status in cancer of the breast

scientific article

Variations in Breast Density and Mammographic Risk Factors in Different Ethnic Groups

Vascular effects of aromatase inhibitors: data from clinical trials.

scientific article published in May 2005

Viridans streptococcal bacteraemia in patients with haematological and solid malignancies

scientific article published on 01 January 1991

Visual assessment of breast density using Visual Analogue Scales: observer variability, reader attributes and reading time

Volumetric and Area-Based Breast Density Measurement in the Predicting Risk of Cancer at Screening (PROCAS) Study

Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis

scientific article published on 17 November 2011

Weight change associated with anastrozole and tamoxifen treatment in postmenopausal women with or at high risk of developing breast cancer

scientific article published on 16 May 2012

West Midlands Oncology Association trials of adjuvant chemotherapy in operable breast cancer: results after a median follow-up of 7 years. II. Patients without involved axillary lymph nodes.

scientific article

White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk

scientific article published on 16 January 2018

Young adulthood body mass index, adult weight gain and breast cancer risk: the PROCAS Study (United Kingdom)

scientific article published on 23 March 2020

Young age at first pregnancy does protect against early onset breast cancer in BRCA1 and BRCA2 mutation carriers.

scientific article published on 7 November 2017

Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases

scientific article published in April 2001

‘For me it's about not feeling like I'm on a diet’: a thematic analysis of women's experiences of an intermittent energy restricted diet to reduce breast cancer risk

scientific article published on 21 June 2018

Paulina is supported by:

About Paulina

Help