List of works - Hubiao Chen

A bioactivity-guided study on the anti-diarrheal activity of Polygonum chinense Linn.

scientific article published on 26 July 2013

A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components ⬇️

scientific article

A comparative tissue-specific metabolite analysis and determination of protodioscin content in Asparagus species used in traditional Chinese medicine and Ayurveda by use of laser microdissection, UHPLC-QTOF/MS and LC-MS/MS.

scientific article

A mixed microscopic method for differentiating seven species of "Bixie"-related Chinese Materia Medica.

scientific article published on 14 November 2013

A novel and rapid HPGPC-based strategy for quality control of saccharide-dominant herbal materials: Dendrobium officinale, a case study.

scientific article published on 9 August 2014

A novel method to identify the Chinese herbal medicine Wuzhimaotao by quantification of laticifers

scientific article

A systematic review of the botanical, phytochemical and pharmacological profile of Dracaena cochinchinensis, a plant source of the ethnomedicine "dragon's blood"

scientific article published on 22 July 2014

A unique issue in the standardization of Chinese materia medica: processing

scientific article

Alkyl and phenolic glycosides from Saussurea stella

scientific article published on 06 April 2013

Alkylphenols from the roots of Ardisia brevicaulis induce G1 arrest and apoptosis through endoplasmic reticulum stress pathway in human non-small-cell lung cancer cells.

scientific article

An experimental study on four kinds of Chinese herbal medicines containing alkaloids using fluorescence microscope and microspectrometer

scientific article

An integrated strategy based on UPLC-DAD-QTOF-MS for metabolism and pharmacokinetic studies of herbal medicines: Tibetan "Snow Lotus" herb (Saussurea laniceps), a case study.

scientific article published on 21 March 2014

Apoptosis sensitization by Euphorbia factor L1 in ABCB1-mediated multidrug resistant K562/ADR cells.

scientific article

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS

scientific article

Authentication of Chinese Materia Medica decoction dregs, part 1: comparison of morphological and microscopic features of four Chinese Materia Medica before and after decoction

scientific article published on 01 April 2011

Authentication of the 31 species of toxic and potent Chinese Materia Medica by light microscopy, Part 3: two species of T/PCMM from flowers and their common adulterants.

scientific article

Authentication of the 31 species of toxic and potent Chinese materia medica by microscopic technique assisted by ICP-MS analysis, part 4: four kinds of toxic and potent mineral arsenical CMMs

scientific article published on 01 January 2011

Carbonic anhydrase IX-directed immunoliposomes for targeted drug delivery to human lung cancer cells in vitro

scientific article

Cell type-specific qualitative and quantitative analysis of saikosaponins in three Bupleurum species using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry

scientific article

Characterization and determination of six flavonoids in the ethnomedicine "Dragon's Blood" by UPLC-PAD-MS.

scientific article

Characterization of Chemical Component Variations in Different Growth Years and Tissues of Morindae Officinalis Radix by Integrating Metabolomics and Glycomics

scientific article published on 20 June 2019

Characterization of flavonoids in the ethomedicine Fordiae Cauliflorae Radix and its adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn.

scientific article

Characterization of secondary metabolites from the raphides of calcium oxalate contained in three araceae family plants using laser microdissection and ultra-high performance liquid chromatography-quadrupole/time of flight-mass spectrometry.

scientific article

Chemical differentiation and quality evaluation of commercial Asian and American ginsengs based on a UHPLC-QTOF/MS/MS metabolomics approach

scientific article published on 2 December 2014

Chemical profile analysis and comparison of two versions of the classic TCM formula Danggui Buxue Tang by HPLC-DAD-ESI-IT-TOF-MSn.

scientific article published on 30 April 2014

Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro.

scientific article

Comparative analysis of EPA and DHA in fish oil nutritional capsules by GC-MS.

scientific article

Comparative chemical analysis of Radix Astragali and Radix Hedysari by HPLC

scientific article published on 20 October 2011

Comparative study on intestinal metabolism and absorption in vivo of ginsenosides in sulphur-fumigated and non-fumigated ginseng by ultra performance liquid chromatography quadruple time-of-flight mass spectrometry based chemical profiling approach.

scientific article published on 22 May 2014

Comparison of chemical profiles between the root and aerial parts from three Bupleurum species based on a UHPLC-QTOF-MS metabolomics approach

scientific article

Comparison of contents of five ephedrine alkaloids in three official origins of Ephedra Herb in China by high-performance liquid chromatography

scientific article published on 06 April 2011

Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry.

scientific article

Comparison of the anti-inflammatory and anti-nociceptive effects of three medicinal plants known as "Snow Lotus" herb in traditional Uighur and Tibetan medicines

scientific article published on 18 January 2010

Comparison of the chemical composition and pharmacological effects of the aqueous and ethanolic extracts from a Tibetan "Snow Lotus" (Saussurea laniceps) herb.

scientific article published on 12 June 2012

Comparison of the chemical profiles and anti-platelet aggregation effects of two "Dragon's Blood" drugs used in traditional Chinese medicine

scientific article published on 10 November 2010

Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari.

scientific article

Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD.

scientific article published on 30 August 2014

Correlation between Quality and Geographical Origins of Revealed by Qualitative Fingerprint Profiling and Quantitative Determination of Triterpenoid Acids

scientific article published on 31 August 2018

Determination of five flavonoids in different parts of Fordia cauliflora by ultra performance liquid chromatography/triple-quadrupole mass spectrometry and chemical comparison with the root of Millettia pulchra var. laxior.

scientific article published on 19 July 2013

Determination of ginsenosides in Asian and American ginsengs by liquid chromatography-quadrupole/time-of-flight MS: assessing variations based on morphological characteristics.

scientific article

Determination of the content of rosmarinic acid by HPLC and analytical comparison of volatile constituents by GC-MS in different parts of Perilla frutescens (L.) Britt ⬇️

scientific article

Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation--rationale, methods and preliminary results from a Sino-American collaboration

scientific article

Development of high-performance liquid chromatographic fingerprint for quality analysis of Hedysari Radix

scientific article published on 6 December 2012

Distribution of toxic alkaloids in tissues from three herbal medicine Aconitum species using laser micro-dissection, UHPLC-QTOF MS and LC-MS/MS techniques

scientific article

Fingerprint analysis of processed Rhizoma Chuanxiong by high-performance liquid chromatography coupled with diode array detection

scientific article

Food-Derived Nanoscopic Drug Delivery Systems for Treatment of Rheumatoid Arthritis

scientific article published on 31 July 2020

HSCCC-based strategy for preparative separation of in vivo metabolites after administration of an herbal medicine: Saussurea laniceps, a case study

scientific article

Heavy metal and pesticide content in commonly prescribed individual raw Chinese Herbal Medicines

scientific article

Histochemical analysis of the root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae) ⬇️

scientific article published on 13 October 2010

Identification of Chinese herbal medicines by fluorescence microscopy: fluorescent characteristics of medicinal bark.

scientific article

Identification of Daqingye and Banlangen including crude drugs and decoction dregs from three plant species by normal light and fluorescence microscopy

scientific article published on 16 May 2013

Identification of the botanical source of stemonae radix based on polymerase chain reaction with specific primers and polymerase chain reaction-restriction fragment length polymorphism

scientific article published on 01 September 2009

Localization of ginsenosides in the rhizome and root of Panax ginseng by laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry

scientific article published on 12 December 2014

Metabolite profiling of tissues of Acorus calamus and Acorus tatarinowii rhizomes by using LMD, UHPLC-QTOF MS, and GC-MS.

scientific article published on 11 March 2015

Microscopic research on a multi-source traditional Chinese medicine, Astragali Radix

scientific article published on 2 October 2013

Molecular analysis of Stemona plants in China based on sequences of four chloroplast DNA regions

scientific article published in August 2009

Oolong tea: A critical review of processing methods, chemical composition, health effects, and risk

scientific article published on 5 July 2017

Profiling of secondary metabolites in tissues from Rheum palmatum L. using laser microdissection and liquid chromatography mass spectrometry.

scientific article

Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography

scientific article

Quantitative comparison of multiple components in Dioscorea nipponica and D. panthaica by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

scientific article

Quercetin induces apoptosis via the mitochondrial pathway in KB and KBv200 cells.

scientific article published on 22 February 2013

Rapid Fingerprint Analysis of Flos Carthami by Ultra-Performance Liquid Chromatography and Similarity Evaluation

scientific article

Saussurea involucrata: A review of the botany, phytochemistry and ethnopharmacology of a rare traditional herbal medicine.

scientific article published on 23 June 2015

Simultaneous quantification of five major constituents in stems of Dracaena plants and related medicinal preparations from China and Vietnam by HPLC-DAD.

scientific article

Structural diversity requires individual optimization of ethanol concentration in polysaccharide precipitation

scientific article published on 27 March 2014

Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway. ⬇️

scientific article published on 15 April 2011

Study of the relationship between genetics and geography in determining the quality of Astragali Radix

scientific article published in January 2011

The critical roles of mitophagy in cerebral ischemia

scientific article

The melanogenesis-inhibitory effect and the percutaneous formulation of ginsenoside Rb1

scientific article

The variation in the major constituents of the dried rhizome of Ligusticum chuanxiong (Chuanxiong) after herbal processing

scientific article (publication date: 2016)

Tissue-Specific Analysis of Secondary Metabolites Creates a Reliable Morphological Criterion for Quality Grading of Polygoni Multiflori Radix.

scientific article published on 8 May 2018

Tissue-specific metabolite profiling and quantitative analysis of ginsenosides in Panax quinquefolium using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry

scientific article published on 9 December 2015

Tissue-specific metabolite profiling of Cyperus rotundus L. rhizomes and (+)-nootkatone quantitation by laser microdissection, ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry, and gas chromatography-mass spec

scientific article

Tissue-specific metabolite profiling of Turmeric by using laser micro-dissection, ultra-high performance liquid chromatography-quadrupole time of fight-mass spectrometry and liquid chromatography-tandem mass spectrometry.

scientific article published on January 2014

Tissue-specific metabolite profiling of alkaloids in Sinomenii Caulis using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry.

scientific article

UPLC-QTOF-MS identification of metabolites in rat biosamples after oral administration of Dioscorea saponins: a comparative study.

scientific article published on 16 February 2015

Ultrasound-Assisted Extraction May Not Be a Better Alternative Approach than Conventional Boiling for Extracting Polysaccharides from Herbal Medicines.

scientific article published on 18 November 2016

List of works by Hubiao Chen

A bioactivity-guided study on the anti-diarrheal activity of Polygonum chinense Linn.

A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components ⬇️

A comparative tissue-specific metabolite analysis and determination of protodioscin content in Asparagus species used in traditional Chinese medicine and Ayurveda by use of laser microdissection, UHPLC-QTOF/MS and LC-MS/MS.

A mixed microscopic method for differentiating seven species of "Bixie"-related Chinese Materia Medica.

A novel and rapid HPGPC-based strategy for quality control of saccharide-dominant herbal materials: Dendrobium officinale, a case study.

A novel method to identify the Chinese herbal medicine Wuzhimaotao by quantification of laticifers

A systematic review of the botanical, phytochemical and pharmacological profile of Dracaena cochinchinensis, a plant source of the ethnomedicine "dragon's blood"

A unique issue in the standardization of Chinese materia medica: processing

Alkyl and phenolic glycosides from Saussurea stella

Alkylphenols from the roots of Ardisia brevicaulis induce G1 arrest and apoptosis through endoplasmic reticulum stress pathway in human non-small-cell lung cancer cells.

An experimental study on four kinds of Chinese herbal medicines containing alkaloids using fluorescence microscope and microspectrometer

An integrated strategy based on UPLC-DAD-QTOF-MS for metabolism and pharmacokinetic studies of herbal medicines: Tibetan "Snow Lotus" herb (Saussurea laniceps), a case study.

Apoptosis sensitization by Euphorbia factor L1 in ABCB1-mediated multidrug resistant K562/ADR cells.

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS

Authentication of Chinese Materia Medica decoction dregs, part 1: comparison of morphological and microscopic features of four Chinese Materia Medica before and after decoction

Authentication of the 31 species of toxic and potent Chinese Materia Medica by light microscopy, Part 3: two species of T/PCMM from flowers and their common adulterants.

Authentication of the 31 species of toxic and potent Chinese materia medica by microscopic technique assisted by ICP-MS analysis, part 4: four kinds of toxic and potent mineral arsenical CMMs

Carbonic anhydrase IX-directed immunoliposomes for targeted drug delivery to human lung cancer cells in vitro

Cell type-specific qualitative and quantitative analysis of saikosaponins in three Bupleurum species using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry

Characterization and determination of six flavonoids in the ethnomedicine "Dragon's Blood" by UPLC-PAD-MS.

Characterization of Chemical Component Variations in Different Growth Years and Tissues of Morindae Officinalis Radix by Integrating Metabolomics and Glycomics

Characterization of flavonoids in the ethomedicine Fordiae Cauliflorae Radix and its adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn.

Characterization of secondary metabolites from the raphides of calcium oxalate contained in three araceae family plants using laser microdissection and ultra-high performance liquid chromatography-quadrupole/time of flight-mass spectrometry.

Chemical differentiation and quality evaluation of commercial Asian and American ginsengs based on a UHPLC-QTOF/MS/MS metabolomics approach

Chemical profile analysis and comparison of two versions of the classic TCM formula Danggui Buxue Tang by HPLC-DAD-ESI-IT-TOF-MSn.

Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro.

Comparative analysis of EPA and DHA in fish oil nutritional capsules by GC-MS.

Comparative chemical analysis of Radix Astragali and Radix Hedysari by HPLC

Comparative study on intestinal metabolism and absorption in vivo of ginsenosides in sulphur-fumigated and non-fumigated ginseng by ultra performance liquid chromatography quadruple time-of-flight mass spectrometry based chemical profiling approach.

Comparison of chemical profiles between the root and aerial parts from three Bupleurum species based on a UHPLC-QTOF-MS metabolomics approach

Comparison of contents of five ephedrine alkaloids in three official origins of Ephedra Herb in China by high-performance liquid chromatography

Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry.

Comparison of the anti-inflammatory and anti-nociceptive effects of three medicinal plants known as "Snow Lotus" herb in traditional Uighur and Tibetan medicines

Comparison of the chemical composition and pharmacological effects of the aqueous and ethanolic extracts from a Tibetan "Snow Lotus" (Saussurea laniceps) herb.

Comparison of the chemical profiles and anti-platelet aggregation effects of two "Dragon's Blood" drugs used in traditional Chinese medicine

Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari.

Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD.

Correlation between Quality and Geographical Origins of Revealed by Qualitative Fingerprint Profiling and Quantitative Determination of Triterpenoid Acids

Determination of five flavonoids in different parts of Fordia cauliflora by ultra performance liquid chromatography/triple-quadrupole mass spectrometry and chemical comparison with the root of Millettia pulchra var. laxior.

Determination of ginsenosides in Asian and American ginsengs by liquid chromatography-quadrupole/time-of-flight MS: assessing variations based on morphological characteristics.

Determination of the content of rosmarinic acid by HPLC and analytical comparison of volatile constituents by GC-MS in different parts of Perilla frutescens (L.) Britt ⬇️

Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation--rationale, methods and preliminary results from a Sino-American collaboration

Development of high-performance liquid chromatographic fingerprint for quality analysis of Hedysari Radix

Distribution of toxic alkaloids in tissues from three herbal medicine Aconitum species using laser micro-dissection, UHPLC-QTOF MS and LC-MS/MS techniques

Fingerprint analysis of processed Rhizoma Chuanxiong by high-performance liquid chromatography coupled with diode array detection

Food-Derived Nanoscopic Drug Delivery Systems for Treatment of Rheumatoid Arthritis

HSCCC-based strategy for preparative separation of in vivo metabolites after administration of an herbal medicine: Saussurea laniceps, a case study

Heavy metal and pesticide content in commonly prescribed individual raw Chinese Herbal Medicines

Histochemical analysis of the root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae) ⬇️

Identification of Chinese herbal medicines by fluorescence microscopy: fluorescent characteristics of medicinal bark.

Identification of Daqingye and Banlangen including crude drugs and decoction dregs from three plant species by normal light and fluorescence microscopy

Identification of the botanical source of stemonae radix based on polymerase chain reaction with specific primers and polymerase chain reaction-restriction fragment length polymorphism

Localization of ginsenosides in the rhizome and root of Panax ginseng by laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry

Metabolite profiling of tissues of Acorus calamus and Acorus tatarinowii rhizomes by using LMD, UHPLC-QTOF MS, and GC-MS.

Microscopic research on a multi-source traditional Chinese medicine, Astragali Radix

Molecular analysis of Stemona plants in China based on sequences of four chloroplast DNA regions

Oolong tea: A critical review of processing methods, chemical composition, health effects, and risk

Profiling of secondary metabolites in tissues from Rheum palmatum L. using laser microdissection and liquid chromatography mass spectrometry.

Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography

Quantitative comparison of multiple components in Dioscorea nipponica and D. panthaica by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

Quercetin induces apoptosis via the mitochondrial pathway in KB and KBv200 cells.

Rapid Fingerprint Analysis of Flos Carthami by Ultra-Performance Liquid Chromatography and Similarity Evaluation

Saussurea involucrata: A review of the botany, phytochemistry and ethnopharmacology of a rare traditional herbal medicine.

Simultaneous quantification of five major constituents in stems of Dracaena plants and related medicinal preparations from China and Vietnam by HPLC-DAD.

Structural diversity requires individual optimization of ethanol concentration in polysaccharide precipitation

Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway. ⬇️

Study of the relationship between genetics and geography in determining the quality of Astragali Radix

The critical roles of mitophagy in cerebral ischemia

The melanogenesis-inhibitory effect and the percutaneous formulation of ginsenoside Rb1

The variation in the major constituents of the dried rhizome of Ligusticum chuanxiong (Chuanxiong) after herbal processing

Tissue-Specific Analysis of Secondary Metabolites Creates a Reliable Morphological Criterion for Quality Grading of Polygoni Multiflori Radix.

Tissue-specific metabolite profiling and quantitative analysis of ginsenosides in Panax quinquefolium using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry

Tissue-specific metabolite profiling of Cyperus rotundus L. rhizomes and (+)-nootkatone quantitation by laser microdissection, ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry, and gas chromatography-mass spec

Tissue-specific metabolite profiling of Turmeric by using laser micro-dissection, ultra-high performance liquid chromatography-quadrupole time of fight-mass spectrometry and liquid chromatography-tandem mass spectrometry.

Tissue-specific metabolite profiling of alkaloids in Sinomenii Caulis using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry.

UPLC-QTOF-MS identification of metabolites in rat biosamples after oral administration of Dioscorea saponins: a comparative study.

Ultrasound-Assisted Extraction May Not Be a Better Alternative Approach than Conventional Boiling for Extracting Polysaccharides from Herbal Medicines.