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List of works by Eduardo Magalhães Rego

(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.

scientific article

(-)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1

scientific article published on 27 April 2021

35 years of the Brazilian Journal of Medical and Biological Research

scientific article published on 6 February 2017

A 23-year-old woman with 11q-chronic lymphocytic leukemia.

scientific article published on 4 May 2010

A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings?

scientific article published on 30 September 2020

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

scientific article published on 13 April 2015

Acute myeloid leukemia (AML-M2) with t(5;11)(q35;q13) and normal expression of cyclin D1.

scientific article published in January 2007

Acute myeloid leukemia with e1a2 BCR-ABL1 fusion gene: two cases with peculiar molecular and clinical presentations.

scientific article published on 3 August 2017

Acute promyelocytic leukemia associated with the PLZF-RARA fusion gene: two additional cases with clinical and laboratorial peculiar presentations

scientific article published on 29 December 2011

Adhesion molecules and Differentiation Syndrome: phenotypic and functional analysis of the effect of ATRA, As2O3, phenylbutyrate, and G-CSF in acute promyelocytic leukemia

scientific article published in December 2007

All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies

scientific article published on 15 May 2015

Analysis of five polymorphic DNA markers for indirect genetic diagnosis of haemophilia A in the Brazilian population

scientific article published on 7 June 2011

Anti-inflammatory effects of atorvastatin: modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene

scientific article published on 30 August 2006

Antinociception induced by intracerebroventricular or intrathecal administration of gentamicin in rats

scientific article published on 01 May 1992

Antinociception induced by intraperitoneal injection of gentamicin in rats and mice

scientific article published on 01 June 1990

Apoptosis induction by (+)alpha-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells.

scientific article

Association between the TP53 Arg72Pro polymorphism and clinical outcomes in acute myeloid leukemia

scientific article published on 20 October 2016

Biological X-ray irradiator characterization for use with small animals and cells

scientific article

Blastoid mantle cell lymphoma with t(2;8) (p12;q24)

scientific article published on 01 October 2007

CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice.

scientific article published on 27 May 2019

CD10 and CD19 fluorescence intensity of B-cell precursors in normal and leukemic bone marrow. Clinical characterization of CD10(+strong) and CD10(+weak) common acute lymphoblastic leukemia

scientific article published on 01 May 1999

Cardiac stunning as a manifestation of ATRA differentiation syndrome in acute promyelocytic leukemia

scientific article published on 26 January 2011

Characterization of acute lymphoblastic leukemia subtypes in Brazilian patients

scientific article published on 01 April 1996

Characterization of conserved and novel septal factors in Mycobacterium smegmatis

scientific article published on 8 January 2018

Characterization of myeloid or lymphoid acute leukemia by a chemiluminescence assay. Comparison with immunocytochemistry using an antimyeloperoxidase antibody.

scientific article published in January 1993

Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines

scientific article published on 01 October 2007

Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia

scientific article published on 15 September 2017

Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia

scientific article published on 10 July 2019

Comparative analysis of the pathological events involved in immune and non-immune TRALI models.

scientific article

Comparative genomic analysis of PML and RARA breakpoints in paired diagnosis/relapse samples of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.

scientific article published on 24 August 2017

Comparison of microRNA expression in high-count monoclonal B-cell lymphocytosis and Binet A chronic lymphocytic leukemia.

scientific article published on 22 April 2017

Determination of P-glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia

scientific article published on 01 May 2008

Development and Evaluation of a Hematology-Oriented Clinical Research Training Program in Latin America.

scientific article

Differential expression of AURKA and AURKB genes in bone marrow stromal mesenchymal cells of myelodysplastic syndrome: correlation with G-banding analysis and FISH.

scientific article published on 22 October 2012

Differentiation syndrome in promyelocytic leukemia: clinical presentation, pathogenesis and treatment.

scientific article published on 24 October 2011

Disrupting membrane raft domains by alkylphospholipids.

scientific article published in February 2013

Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification

scientific article

Epidemiology and treatment of acute promyelocytic leukemia in latin america

scientific article published on 24 October 2011

Evaluation of the European LeukemiaNet recommendations for predicting outcomes of patients with acute myeloid leukemia treated in low- and middle-income countries (LMIC): A Brazilian experience

scientific article published on 24 July 2017

FISH analysis for TET2 deletion in a cohort of 362 Brazilian myeloid malignancies: correlation with karyotype abnormalities.

scientific article

FLORENCE: a randomized, double-blind, phase III pivotal study of febuxostat versus allopurinol for the prevention of tumor lysis syndrome (TLS) in patients with hematologic malignancies at intermediate to high TLS risk.

scientific article

From the molecular model to the impact on prognosis: an overview on acute promyelocytic leukemia

scientific article

GLP overexpression is associated with poor prognosis in Chronic Lymphocytic Leukemia and its inhibition induces leukemic cell death

scientific article published on 31 May 2018

Genetic mutations in patients with acute myeloid leukemia and leukostasis.

scientific article published on 23 March 2013

Granulocyte colony-stimulating factor and leukemogenesis.

scientific article published in June 2004

Guidelines on the treatment of acute myeloid leukemia: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular: Project guidelines: Associação Médica Brasileira - 2015.

scientific article

Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway

scientific article

Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model.

scientific article published on 23 June 2015

High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia.

scientific article published on 21 August 2010

IRS1/β-Catenin Axis Is Activated and Induces MYC Expression in Acute Lymphoblastic Leukemia Cells

scientific article

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

scientific article

Identification of a new translocation that disrupts the RUNX1 gene in a patient with de novo acute myeloid leukemia.

scientific article published on 6 March 2011

Impact of the ICAL on the treatment of acute leukemia

scientific article published on 14 March 2017

Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita

scientific article published on May 2006

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL.

scientific article published on 14 January 2013

In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.

scientific article

Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia.

scientific article published on 8 April 2013

Inhibition of NF- κ B by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ -Radiation Cytotoxicity in Glioblastoma Cells

scientific article

Interaction of 10-(octyloxy) decyl-2-(trimethylammonium) ethyl phosphate with mimetic membranes and cytotoxic effect on leukemic cells.

scientific article

Interleukin-8 is not a predictive biomarker for the development of the acute promyelocytic leukemia differentiation syndrome

scientific article published on 28 August 2020

Intracranial Castleman's disease presenting as hypopituitarism.

scientific article published in October 2004

Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha

scientific article

Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity

scientific article

MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model

scientific article published on 06 April 2021

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape.

scientific article

Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms.

scientific article published on 22 February 2018

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia. ⬇️

scientific article published on 19 April 2012

Microgranular and t(11;17)/PLZF-RARalpha variants of acute promyelocytic leukemia also present the flow cytometric pattern of CD13, CD34, and CD15 expression characteristic of PML-RARalpha gene rearrangement.

scientific article published in May 2004

Modeling dynamics and alternative treatment strategies in acute promyelocytic leukemia

scientific article published on 15 August 2019

Molecular and hematologic relapses in adult patients with acute promyelocytic leukemia: a cohort study

scientific article published on 21 October 2016

Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia

scientific article published on January 2012

Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome

scientific article published on 18 January 2021

Monoclonal B-cell lymphocytosis in first-degree relatives of patients with sporadic (non-familial) chronic lymphocytic leukaemia.

scientific article

Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia

scientific article published on 27 May 2021

Myeloid leukemia with promyelocytic features in transgenic mice expressing hCG-NuMA-RARalpha

scientific article published in January 2004

NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia

scientific article published on 25 June 2020

Outcome of acute myeloid leukemia patients with hyperleukocytosis in Brazil

scientific article published on 25 November 2009

Overexpression of EZH2 associates with a poor prognosis in chronic lymphocytic leukemia.

scientific article

PRAME is a membrane and cytoplasmic protein aberrantly expressed in chronic lymphocytic leukemia and mantle cell lymphoma

scientific article published on 18 April 2006

Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells

scientific article published on 28 September 2017

Post-Sepsis State Induces Tumor-Associated Macrophage Accumulation through CXCR4/CXCL12 and Favors Tumor Progression in Mice.

scientific article published on 27 January 2016

Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia

scientific article

Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups

scientific article published on 26 April 2012

Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study.

scientific article

Reactive oxygen species production triggers green tea-induced anti-leukaemic effects on acute promyelocytic leukaemia model

scientific article

Real-life Outcomes on Acute Promyelocytic Leukemia in Brazil - Early Deaths Are Still a Problem

scientific article published on 12 November 2018

Residual expression of SMYD2 and SMYD3 is associated with the acquisition of complex karyotype in chronic lymphocytic leukemia.

scientific article published on 20 January 2016

Results of FLT3 mutation screening and correlations with immunophenotyping in 169 Brazilian patients with acute myeloid leukemia

scientific article published on 01 February 2010

Reversine triggers mitotic catastrophe and apoptosis in K562 cells.

scientific article published in July 2016

Role of microparticles in the hemostatic dysfunction in acute promyelocytic leukemia

scientific article

Role of promyelocytic leukemia (PML) protein in tumor suppression

scientific article

Salvage treatment for refractory or relapsed acute myeloid leukemia: a 10-year single-center experience

scientific article published on 06 April 2020

Segmental amplification of MLL gene associated with high expression of AURKA and AURKB genes in a case of acute monoblastic leukemia with complex karyotype

scientific article published on 01 April 2010

Single-nucleotide polymorphism array (SNP-A) improves the identification of chromosomal abnormalities by metaphase cytogenetics in myelodysplastic syndrome.

scientific article published on 11 November 2016

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

scientific article

Synthetic phosphoethanolamine has in vitro and in vivo anti-leukemia effects.

scientific article

Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A.

scientific article published on 13 April 2017

Tetrasomy 8 in a patient with chronic lymphocytic leukemia

scientific article published on 01 April 2010

Thalidomide plus dexamethasone as a maintenance therapy after autologous hematopoietic stem cell transplantation improves progression-free survival in multiple myeloma

scientific article published on 23 June 2012

The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylated

scientific article

The Expression of NTAL and Its Protein Interactors Is Associated With Clinical Outcomes in Acute Myeloid Leukemia

scientific article published on 07 May 2021

The association of ICAM-1 Exon 6 (E469K) but not of ICAM-1 Exon 4 (G241R) and PECAM-1 Exon 3 (L125V) polymorphisms with the development of differentiation syndrome in acute promyelocytic leukemia

scientific article

The co-expression of PML/RAR alpha and AML1/ETO fusion genes is associated with ATRA resistance.

scientific article published in February 2005

The emerging story of acute lymphoblastic leukemia among the Latin American population - biological and clinical implications

scientific article published on 14 August 2018

The experience of the International Consortium on Acute Promyelocytic Leukemia in monitoring minimal residual disease in acute promyelocytic leukaemia

scientific article

The expression of DeltaNTP73, TATP73 and TP53 genes in acute myeloid leukaemia is associated with recurrent cytogenetic abnormalities and in vitro susceptibility to cytarabine cytotoxicity

scientific article published on 17 April 2008

The expression of the CD56 antigen is associated with poor prognosis in patients with acute myeloid leukemia

scientific article published on January 2011

The higher expression of alpha and beta isoforms of the human glucocorticoid receptor in leukemic B-progenitors compared to normal CD10+ BM cells does not correlate with methylprednisolone-induced apoptosis.

scientific article published in April 2004

The impact of medical education and networking on the outcome of leukemia treatment in developing countries. The experience of International Consortium on Acute Promyelocytic Leukemia (IC-APL)

scientific article published on 01 April 2012

The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma

scientific article published on 07 May 2019

The presence of CD56/CD16 in T-cell acute lymphoblastic leukaemia correlates with the expression of cytotoxic molecules and is associated with worse response to treatment.

scientific article published on 11 November 2008

The recognition of N-glycans by the lectin ArtinM mediates cell death of a human myeloid leukemia cell line

scientific article (publication date: 2011)

The results of the International Consortium on Acute Promyelocytic Leukemia: a 'proof of concept' of networking as a strategy to improve the outcome of treatment of hematological malignancies in developing countries

scientific article published on January 2013

The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis

scientific journal article

Therapeutic leukapheresis in patients with leukostasis secondary to acute myelogenous leukemia

scholarly article by Gil Cunha De Santis et al published 2011 in Journal of Clinical Apheresis

Translocations t(X;14)(q28;q11) and t(Y;14)(q12;q11) in T-cell prolymphocytic leukemia

scientific article published on 14 February 2008

Treating acute promyelocytic leukaemia in Latin America: lessons from the International Consortium on Acute Leukaemia experience

scientific article published on 3 May 2017

Two critical hits for promyelocytic leukemia

scientific article (publication date: November 2000)

Unraveling KDM4 histone demethylase expression and its association with adverse cytogenetic findings in chronic lymphocytic leukemia

scientific article published on 13 November 2018

ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype

scientific article published on 27 December 2016

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