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List of works by Katherine J. Aitchison

A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression

scientific article published on 15 March 2019

Abnormal cortisol levels during the day and cortisol awakening response in first-episode psychosis: the role of stress and of antipsychotic treatment

scientific article

Adverse reactions to antidepressants

scientific article

Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia

article

Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia

scientific article published on 01 June 1996

An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis

scientific article

An RFLP close to the human collagen I gene COL1A1.

scientific article published on June 1987

Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.

scientific article

Antidepressants and the resilience to early-life stress in inbred mouse strains

scientific article published on December 2011

Apolipoprotein E: depressive illness, depressive symptoms, and Alzheimer's disease.

scientific article published in February 1998

Association analysis between dopamine receptor genes and bipolar affective disorder

article

Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression

scientific article published on 28 February 2017

Association of KIBRA rs17070145 polymorphism with episodic memory in the early stages of a human neurodevelopmental disorder.

scientific article published on 19 July 2014

Association of tardive dyskinesia with variation in CYP2D6: Is there a role for active metabolites?

scientific article published on 4 March 2014

Association study of dopamine receptor gene polymorphisms with drug-induced hallucinations in patients with idiopathic Parkinson's disease

article published in 2000

Associations between the -2548G/A Promoter and Baseline Weight and between Gln223Arg and Lys656Asn Variants and Change in BMI Scores in Arab Children and Adolescents Treated with Risperidone

scientific article published on 05 October 2018

Authors' reply

Benzodiazepines: risks and benefits. A reconsideration

scientific article

Body weight as a predictor of antidepressant efficacy in the GENDEP project

scientific article published on 9 March 2009

CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP.

scientific article published on 17 September 2011

CYP2D6 polymorphisms in Alzheimer's disease, with and without extrapyramidal signs, showing no apolipoprotein E epsilon 4 effect modification

scientific article published in February 1999

Can genetics inform the management of cognitive deficits in schizophrenia?

scientific article published on 10 February 2012

Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors' and Longitudinal ‘Targets'.

scientific article published on 18 December 2012

Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal 'targets'.

scientific article published on 19 September 2012

Case-control, haplotype relative risk and transmission disequilibrium analysis of a dopamine D2 receptor functional promoter polymorphism in schizophrenia

article

Change in sexual dysfunction with aripiprazole: a switching or add-on study

scientific article

Changes in biomarkers of bone turnover in an aripiprazole add-on or switching study

scientific article published on 12 January 2016

Changes in body weight during pharmacological treatment of depression

scientific article published on 18 August 2010

Clinical lessons from GENDEP for the treatment of depression

scientific article published on 22 April 2010

Combining clinical variables to optimize prediction of antidepressant treatment outcomes

scientific article published in April 2016

Comment on Hyperprolactinaemia and antipsychotic therapy in schizophrenia

scientific article published on 01 October 2004

Comments on "Prolactin levels and erectile function in patients treated with risperidone" (J Clin Psychopharmacol 2004;24:161-166).

scientific article published in August 2005

Contribution of genes in the GABAergic pathway to bipolar disorder and its executive function deficit in the Chinese Han population.

scientific article published on 14 November 2017

Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants

scientific article

Copy number variants and therapeutic response to antidepressant medication in major depressive disorder

scientific article published on 21 January 2014

Costs and outcomes associated with an aripiprazole add-on or switching open-label study in psychosis

scientific article

Depressive disorder moderates the effect of the FTO gene on body mass index

article

Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression

scientific article published in March 2009

Differential gene expression analysis in blood of first episode psychosis patients

scientific article published on 19 May 2019

Disclosure of religious beliefs

scientific article published on 01 October 2009

Dissecting the genetic heterogeneity of depression through age at onset

scientific article published on 22 August 2012

Duration of untreated psychosis in adolescents: ethnic differences and clinical profiles

scientific article published on 8 September 2013

Early and delayed onset of response to antidepressants in individual trajectories of change during treatment of major depression: a secondary analysis of data from the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

scientific article

Ecstasy (MDMA)-induced hyponatraemia is associated with genetic variants in CYP2D6 and COMT.

scientific article published in February 2012

Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder

scientific article published on 30 January 2019

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

Effects of antidepressant drug exposure on gene expression in the developing cerebral cortex.

scientific article published on 13 February 2014

Ethnic variations in pathways into early intervention services for psychosis

scientific article

Exploring the role of drug-metabolising enzymes in antidepressant side effects

scientific article published on 12 March 2015

Extracting a needle from a haystack: reanalysis of whole genome data reveals a readily translatable finding.

scientific article

Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation.

scientific article

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

scientific article published on 20 February 2015

Gender differences in antidepressant drug response ⬇️

scientific article published on January 1, 2010

Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

article

Genetic differences in cytochrome P450 enzymes and antidepressant treatment response

scientific article published on 20 November 2013

Genetic predictors of antidepressant side effects: a grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

scientific article published on 10 January 2014

Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.

scientific article published on 29 July 2009

Genetic predictors of response to antidepressants in the GENDEP project

scientific article

Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis

scientific article

Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder

scientific journal article

Genome-wide association analysis of copy number variation in recurrent depressive disorder.

scientific article

Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project

scientific article published on 28 September 2010

Genome-wide association study of major recurrent depression in the U.K. population

scientific article published in June 2010

Genome-wide pharmacogenetics of antidepressant response in the GENDEP project

scientific article

Genomewide association scan of suicidal thoughts and behaviour in major depression

scientific article (publication date: 2011)

Genomics for clinical utility: the future is near

scientific article published on 28 January 2014

Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis

scientific article

History of suicide attempts among patients with depression in the GENDEP project

scientific article published on 22 September 2009

Homozygous osteogenesis imperfecta unlinked to collagen I genes

article

Housekeeping gene expression is affected by antidepressant treatment in a mouse fibroblast cell line

scientific article

Identification of novel polymorphisms in the 5' flanking region of CYP1A2, characterization of interethnic variability, and investigation of their functional significance

scientific article published in November 2000

Implications of Cannabis Legalization on Youth and Young Adults.

scientific article published in January 2018

Interaction Between Functional Genetic Variation of DRD2 and Cannabis Use on Risk of Psychosis

scientific article

Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project.

scientific article published on 9 March 2010

Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals

scientific article

Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study.

scientific article

Interrater reliability of the Antipsychotic Non-Neurological Side-Effects Rating Scale measured in patients treated with clozapine

scientific article published in May 2008

Investigation of blood mRNA biomarkers for suicidality in an independent sample

scientific article

Investigation of the COMT Val158Met variant association with age of onset of psychosis, adjusting for cannabis use.

scientific article published on 6 October 2017

Measuring depression: comparison and integration of three scales in the GENDEP study

scientific article

Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline

scientific article published on 15 March 2011

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

scientific article

Mobile App-Based Self-Report Questionnaires for the Assessment and Monitoring of Bipolar Disorder: Systematic Review

scientific article published on 08 January 2021

Moderation of antidepressant response by the serotonin transporter gene.

scientific article published in July 2009

Modulation of amygdala response and connectivity in depression by serotonin transporter polymorphism and diagnosis.

scientific article published on 2 May 2013

Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder

scientific article published on 5 March 2015

NPAS3 variants in schizophrenia: a neuroimaging study

scientific article

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.

scientific article

No association between genetic markers in BDNF gene and lithium prophylaxis in a Greek sample

article

No evidence for an association of affective disorders with high- or low-activity allele of catechol-o-methyltransferase gene

article

Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumption

scientific article published on 3 October 2011

Pharmacogenetics of antidepressant response

scientific article published on 01 January 2011

Pharmacogenetics of antidepressant response: A polygenic approach

scientific article published on 31 January 2017

Pharmacogenetics: antidepressant drug response

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder

scientific article

Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels

scientific article

Potential role of the combination of galantamine and memantine to improve cognition in schizophrenia

scientific article

Psychiatry and the 'new genetics': hunting for genes for behaviour and drug response

scientific article published in February 2005

Regional distribution of clomipramine and desmethylclomipramine in rat brain and peripheral organs on chronic clomipramine administration.

scientific article published on 24 June 2009

Reply to ‘MDMA can increase cortical levels by 800% in dance clubbers’ Parrott et al ⬇️

scientific article published on January 1, 2013

Role of a Combination of Seven Micronutrients in the Management of Glioblastoma Multiforme.

scientific article published on 12 February 2015

Routine evaluation in first episode psychosis services: feasibility and results from the MiData project

scientific article

Serum and gene expression profile of cytokines in first-episode psychosis

scientific article published on 28 June 2012

Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: clinical description and the role of the 5-HTTLPR.

scientific article published on 9 March 2011

Special issue on Pharmacogenetics

scientific article published on 01 March 2012

Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume

scientific article

Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP.

scientific article published on 6 July 2010

Suicidal ideation during treatment of depression with escitalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial

scientific article

The 12th Annual Pharmacogenetics in Psychiatry meeting report

scientific article

The 8th annual pharmacogenetics in psychiatry meeting report

scientific article

The Ninth Annual Pharmacogenetics in Psychiatry Meeting report

scientific article published in April 2011

The effect of age on DNA concentration from whole saliva: Implications for the standard isolation method

scientific article published on 28 July 2014

The genetics of affective disorder and suicide.

scientific article published on 11 May 2010

Trajectories of Suicidal Ideation During 12 Weeks of Escitalopram or Nortriptyline Antidepressant Treatment Among 811 Patients With Major Depressive Disorder

scientific article published on 16 July 2019

Trajectories of change in depression severity during treatment with antidepressants

scientific article published on 29 October 2009

Transcriptomics and the mechanisms of antidepressant efficacy

scientific article published on 12 November 2015

Trend level gene-gender interaction effect for the BDNF rs6265 variant on age of onset of psychosis

scientific article published on 08 August 2019

Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response

scientific article

Variation in GNB3 predicts response and adverse reactions to antidepressants

scientific article published on 8 September 2010

Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing population

scientific article published in May 2006

Weight gain and other metabolic adverse effects associated with atypical antipsychotic treatment of children and adolescents: a systematic review and meta-analysis

scientific article published on April 2013

White matter abnormalities and illness severity in major depressive disorder.

scientific article published on 10 May 2012

Workshop outcomes report: Initiatives to establish a European Network of pharmacogenetics/genomics and progress

scientific article published on 24 March 2007

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