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List of works by Thomas L. Andresen

18F-FDG PET/CT-based early treatment response evaluation of nanoparticle-assisted photothermal cancer therapy

scientific article

3D Biomaterial Microarrays for Regenerative Medicine: Current State-of-the-Art, Emerging Directions and Future Trends

scientific article published on 26 November 2015

64Cu loaded liposomes as positron emission tomography imaging agents

scientific article published on 7 January 2011

A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes

scientific article published on 13 December 2019

A concise synthesis of castanospermine by the use of a transannular cyclization

scientific article published in November 2009

A hydrogel based nanosensor with an unprecedented broad sensitivity range for pH measurements in cellular compartments.

scientific article published on 22 September 2015

A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies.

scientific article

A quantitative <i>ex vivo</i> study of the interactions between reconstituted high-density lipoproteins and human leukocytes

scientific article published on 23 January 2020

A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue

scientific article published on May 2011

A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response

scientific article published on 25 March 2019

Activation of interfacial enzymes at membrane surfaces

scientific article published on 28 June 2006

Activation of the human complement system by cholesterol-rich and PEGylated liposomes-modulation of cholesterol-rich liposome-mediated complement activation by elevated serum LDL and HDL levels

Acylation of Glucagon-like peptide-2: interaction with lipid membranes and in vitro intestinal permeability

scientific article

Acylation of salmon calcitonin modulates in vitro intestinal peptide flux through membrane permeability enhancement

scientific article published on 5 September 2015

Adsorption of cationic peptides to solid surfaces of glass and plastic

scientific article published on May 2015

Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific drug release.

scientific article

Affinity Induced Surface Functionalization of Liposomes Using Cu-Free Click Chemistry

scientific article published on 17 June 2016

An assessment of the importance of exposure routes to the uptake and internal localisation of fluorescent nanoparticles in zebrafish (Danio rerio), using light sheet microscopy.

scientific article published on 11 March 2017

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles.

scientific article

Applying Fluorescence Correlation Spectroscopy to Investigate Peptide-Induced Membrane Disruption.

scientific article published in January 2017

Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells.

scientific article

Binding of human serum albumin to PEGylated liposomes: insights into binding numbers and dynamics by fluorescence correlation spectroscopy

scientific article published on 22 November 2016

Blending Electronics with the Human Body: A Pathway toward a Cybernetic Future

scientific article published on 01 August 2018

Brain tumor vessels-a barrier for drug delivery

scientific article published on 02 June 2020

Catalyst-free conjugation and in situ quantification of nanoparticle ligand surface density using fluorogenic Cu-free Click chemistry

scientific article published on 15 February 2011

Combinatorial Screening of Nanoclay-Reinforced Hydrogels: A Glimpse of the “Holy Grail” in Orthopedic Stem Cell Therapy?

Complement activation by PEG-functionalized multi-walled carbon nanotubes is independent of PEG molecular mass and surface density.

scientific article published on 19 February 2013

Complement activation cascade triggered by PEG-PL engineered nanomedicines and carbon nanotubes: the challenges ahead

scientific article published on 11 April 2010

Complement-mediated tumour growth: implications for cancer nanotechnology and nanomedicines

scientific article published on 14 March 2009

Complement: alive and kicking nanomedicines.

scientific article published on August 2009

Complex surface concentration gradients by stenciled "electro click chemistry".

scientific article published on October 2010

Delivery of TLR7 agonist to monocytes and dendritic cells by DCIR targeted liposomes induces robust production of anti-cancer cytokines

scientific article published on 30 January 2017

Design, calibration and application of broad-range optical nanosensors for determining intracellular pH.

scientific article published on 20 November 2014

Differential toxicological response to positively and negatively charged nanoparticles in the rat brain.

scientific article published in November 2014

Dissociation of fluorescently labeled lipids from liposomes in biological environments challenges the interpretation of uptake studies

scientific article published on 01 December 2018

Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering

scientific article published on 28 October 2010

Domain-induced activation of human phospholipase A2 type IIA: local versus global lipid composition.

scientific article

Drug delivery by an enzyme-mediated cyclization of a lipid prodrug with unique bilayer-formation properties

scientific article

Effective nanoparticle-based gene delivery by a protease triggered charge switch

scientific article published on 20 March 2014

Elucidating the interplay between DNA-condensing and free polycations in gene transfection through a mechanistic study of linear and branched PEI

scientific article published on 01 September 2011

Elucidating the role of free polycations in gene knockdown by siRNA polyplexes

scientific article published on 13 February 2016

Endothelial Protein C-Targeting Liposomes Show Enhanced Uptake and Improved Therapeutic Efficacy in Human Retinal Endothelial Cells.

scientific article published in April 2018

Engineering liposomes and nanoparticles for biological targeting.

scientific article published on January 2011

Enhanced efficacy of sublingual immunotherapy by liposome-mediated delivery of allergen.

scientific article published on 22 November 2017

Enhancing adoptive CD8 T cell therapy by systemic delivery of tumor associated antigens

scientific article published on 05 October 2021

Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs.

scientific article published in March 2004

Enzyme-triggered nanomedicine: drug release strategies in cancer therapy.

scientific article published on 13 October 2010

Evaluating nanoparticle sensor design for intracellular pH measurements.

scientific article

Expanding the dynamic measurement range for polymeric nanoparticle pH sensors

scientific article published on 30 March 2011

Facing the Design Challenges of Particle-Based Nanosensors for Metabolite Quantification in Living Cells.

scientific article published on 05 August 2015

Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective

scientific article published on 24 October 2011

Feasibility of a novel liquid fiducial marker for use in image guided radiotherapy of oesophageal cancer

scientific article published on 09 July 2018

Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts

Handling a tricycle: orthogonal versus random oxidation of the tricyclic inhibitor cystine knotted peptide gurmarin

scientific article published on 03 July 2012

How To Characterize Individual Nanosize Liposomes with Simple Self-Calibrating Fluorescence Microscopy

scientific article published on 19 April 2018

Hyaluronic acid immobilized polyacrylamide nanoparticle sensors for CD44 receptor targeting and pH measurement in cells

scientific article published on 12 November 2012

Impedimetric toxicity assay in microfluidics using free and liposome-encapsulated anticancer drugs

scientific article published on 4 February 2015

In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines.

scientific article published on 3 August 2016

In vivo evaluation of PEGylated ⁶⁴Cu-liposomes with theranostic and radiotherapeutic potential using micro PET/CT.

scientific article published on 8 December 2015

In vivo toxicity of cationic micelles and liposomes

article

Injectable Colloidal Gold for Use in Intrafractional 2D Image-Guided Radiation Therapy

Injectable colloidal gold in a sucrose acetate isobutyrate gelating matrix with potential use in radiation therapy

scientific article published on 15 April 2014

Injectable iodine-125 labeled tissue marker for radioactive localization of non-palpable breast lesions

scientific article published on 19 October 2017

Injectable silver nanosensors: in vivo dosimetry for external beam radiotherapy using positron emission tomography

scientific article published on 13 May 2016

Interdependence of initial cell density, drug concentration and exposure time revealed by real-time impedance spectroscopic cytotoxicity assay

scientific article

Investigation of enzyme-sensitive lipid nanoparticles for delivery of siRNA to blood-brain barrier and glioma cells

scientific article published on 24 September 2015

Liposomal formulation of retinoids designed for enzyme triggered release

scientific article published on May 2010

Liposome accumulation in irradiated tumors display important tumor and dose dependent differences

scientific article published on 4 September 2017

Liposome imaging agents in personalized medicine

scientific article published on 12 September 2012

Liposome-encapsulated chemotherapy: Current evidence for its use in companion animals.

scientific article

Liposomes containing alkylated methotrexate analogues for phospholipase A(2) mediated tumor targeted drug delivery

scientific article

Liquid fiducial marker applicability in proton therapy of locally advanced lung cancer.

scientific article published on 16 January 2017

Liquid fiducial marker performance during radiotherapy of locally advanced non small cell lung cancer

scientific article published on 18 July 2016

Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer

scientific article published on 02 August 2018

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

scientific article

Material properties in complement activation

scientific article published on 12 June 2011

Mechanistic study of the sPLA2-mediated hydrolysis of a thio-ester pro anticancer ether lipid.

scientific article

Methotrexate prodrugs sensitive to reactive oxygen species for the improved treatment of rheumatoid arthritis

scientific article published on 20 July 2018

Methylation of the phosphate oxygen moiety of phospholipid-methoxy(polyethylene glycol) conjugate prevents PEGylated liposome-mediated complement activation and anaphylatoxin production

scientific article published on 25 October 2006

Micromotors for drug delivery in vivo: The road ahead

scientific article published on 17 September 2018

Micropatterning of functional conductive polymers with multiple surface chemistries in register

scientific article published on 03 April 2012

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

scientific article published on 10 January 2019

Monocyte targeting and activation by cationic liposomes formulated with a TLR7 agonist.

scientific article published on 15 February 2015

Mouse Positron Emission Tomography Study of the Biodistribution of Gold Nanoparticles with Different Surface Coatings Using Embedded Copper-64

Multicompartment Artificial Organelles Conducting Enzymatic Cascade Reactions inside Cells.

scientific article published on 24 January 2017

Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage

scientific article published on 18 July 2018

Multimodal soft tissue markers for bridging high-resolution diagnostic imaging with therapeutic intervention

scientific article published on 19 August 2020

Multiplexed Dosing Assays by Digitally Definable Hydrogel Volumes

scientific article published on 30 November 2015

Nanomechanical IR spectroscopy for fast analysis of liquid-dispersed engineered nanomaterials

On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems - A commentary

scientific article published on 7 November 2017

Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors

scientific article published on 01 July 2021

PET imaging of liposomes labeled with an [18F]-fluorocholesteryl ether probe prepared by automated radiosynthesis

PET imaging with copper-64 as a tool for real-time in vivo investigations of the necessity for cross-linking of polymeric micelles in nanomedicine

scientific article published on 13 April 2017

Particulate systems for targeting of macrophages: basic and therapeutic concepts.

scientific article published on 19 June 2012

Polymeric pH nanosensor with extended measurement range bearing octaarginine as cell penetrating peptide

scientific article published on February 2016

Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes

scientific article

Positron emission tomography based analysis of long-circulating cross-linked triblock polymeric micelles in a U87MG mouse xenograft model and comparison of DOTA and CB-TE2A as chelators of copper-64.

scientific article published on 7 April 2014

Positron emission tomography evaluation of somatostatin receptor targeted 64Cu-TATE-liposomes in a human neuroendocrine carcinoma mouse model

scientific article published on 5 January 2012

Propargylamine-isothiocyanate reaction: efficient conjugation chemistry in aqueous media

scientific article

Prostaglandin phospholipid conjugates with unusual biophysical and cytotoxic properties.

scientific article published on 12 June 2010

Protein Transduction Domain Mimics Facilitate Rapid Antigen Delivery into Monocytes

scientific article published on 16 May 2019

Quantification and comparison of visibility and image artifacts of a new liquid fiducial marker in a lung phantom for image-guided radiation therapy.

scientific article

Quantification of leakage from large unilamellar lipid vesicles by fluorescence correlation spectroscopy.

scientific article published on 15 August 2014

Quantitative evaluation of bioorthogonal chemistries for surface functionalization of nanoparticles.

scientific article

Recent advances in compartmentalized synthetic architectures as drug carriers, cell mimics and artificial organelles.

scientific article published on 16 January 2017

Remote Loading of (64)Cu(2+) into Liposomes without the Use of Ion Transport Enhancers

scientific article published on October 2015

Remote loading of liposomes with a I-radioiodinated compound and their evaluation by PET/CT in a murine tumor model

Remote-loading of liposomes with manganese-52 and in vivo evaluation of the stabilities of 52Mn-DOTA and 64Cu-DOTA using radiolabelled liposomes and PET imaging

scientific article

Revisit complexation between DNA and polyethylenimine — Effect of length of free polycationic chains on gene transfection ⬇️

scientific article published on March 30, 2011

Revisiting the use of sPLA2-sensitive liposomes in cancer therapy

scientific article published on 26 June 2017

Secreted phospholipase A(2) as a new enzymatic trigger mechanism for localised liposomal drug release and absorption in diseased tissue

scientific article published on 01 January 2003

Secretory phospholipase A2 activity toward diverse substrates.

scientific article published on 11 May 2011

Secretory phospholipase A2 hydrolysis of phospholipid analogues is dependent on water accessibility to the active site

scientific article published on 10 April 2007

Secretory phospholipase A2 responsive liposomes exhibit a potent anti-neoplastic effect in vitro, but induce unforeseen severe toxicity in vivo

scientific article

Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x.

scientific article published on January 2011

Side chain hydrophobicity modulates therapeutic activity and membrane selectivity of antimicrobial peptide mastoparan-X.

scientific article

Single-vesicle detection and analysis of peptide-induced membrane permeabilization

scientific article published on 20 February 2015

Single-walled carbon nanotube surface control of complement recognition and activation.

scientific article

Solid-phase synthesis of PEGylated lipopeptides using click chemistry

scientific article published on 01 May 2010

Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis.

scientific article published on 31 March 2018

Synthesis and biophysical characterization of chlorambucil anticancer ether lipid prodrugs

scientific article published on May 2009

Synthesis and characterization of ratiometric nanosensors for pH quantification: a mixed micelle approach

scientific article published on 30 March 2012

Synthesis and membrane behavior of a new class of unnatural phospholipid analogs useful as phospholipase A2 degradable liposomal drug carriers.

scientific article

Synthesis of Cross-Linked Polymeric Micelle pH Nanosensors: An Investigation of Design Flexibility

scientific article published on 2 July 2015

Synthesis of sn-1 functionalized phospholipids as substrates for secretory phospholipase A2

scientific article published on 07 January 2007

Synthesis of tocopheryl succinate phospholipid conjugates and monitoring of phospholipase A2 activity ⬇️

scientific article published on May 17, 2012

Targeting the transferrin receptor for brain drug delivery

scientific article published on 31 July 2019

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

scientific article published on 4 September 2017

The Composition of Reconstituted High-Density Lipoproteins (rHDL) Dictates the Degree of rHDL Cargo- and Size-Remodeling via Direct Interactions with Endogenous Lipoproteins

scientific article published on 19 September 2019

The diffusion dynamics of PEGylated liposomes in the intact vitreous of the ex vivo porcine eye: A fluorescence correlation spectroscopy and biodistribution study.

scientific article published on 3 March 2017

The hard protein corona of stealth liposomes is sparse

scientific article published on 03 June 2019

Theranostic Imaging May Vaccinate against the Therapeutic Benefit of Long Circulating PEGylated Liposomes and Change Cargo Pharmacokinetics

scientific article published on 31 October 2018

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer

scientific article

Thermodynamic profiling of peptide membrane interactions by isothermal titration calorimetry: a search for pores and micelles

scientific article published on July 2011

Topical delivery of vismodegib using ablative fractional laser and micro-emulsion formulation in vitro

scientific article published on 28 August 2018

Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoietin: a strategy to enable protein delivery to the brain

scientific article published on 14 March 2017

Tumor repolarization by an advanced liposomal drug delivery system provides a potent new approach for chemo-immunotherapy

scientific article published on 04 September 2020

Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells

scientific article published on 02 April 2021

Understanding detergent effects on lipid membranes: a model study of lysolipids

scientific article

Unique Calibrators Derived from Fluorescence-Activated Nanoparticle Sorting for Flow Cytometric Size Estimation of Artificial Vesicles: Possibilities and Limitations

scientific article published on 23 May 2019

What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer

scientific article published on 07 December 2018

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