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List of works by Nicola Baldini

A Multicentric, Open-Label, Randomized, Comparative Clinical Trial of Two Different Doses of Expanded hBM-MSCs Plus Biomaterial versus Iliac Crest Autograft, for Bone Healing in Nonunions after Long Bone Fractures: Study Protocol.

scientific article

A comparison of hemiarthroplasty with a novel polycarbonate-urethane acetabular component for displaced intracapsular fractures of the femoral neck: a randomised controlled trial in elderly patients

scientific article

A novel biomaterial for osteotropic drug nanocarriers: synthesis and biocompatibility evaluation of a PLGA-ALE conjugate

scientific article

A novel technique for decellularization of allogenic nerves and in vivo study of their use for peripheral nerve reconstruction.

scientific article published on 20 April 2017

A preliminary in vitro and in vivo study of the effects of new anthraquinones on neutrophils and bone remodeling.

scientific article published in November 2005

A prospective, randomised, controlled trial using a Mg-hydroxyapatite - demineralized bone matrix nanocomposite in tibial osteotomy

scientific article published on 28 September 2011

A regenerative approach for bone repair in congenital pseudarthrosis of the tibia associated or not associated with type 1 neurofibromatosis: correlation between laboratory findings and clinical outcome

scientific article published on 22 November 2011

Acridine Orange is an Effective Anti-Cancer Drug that Affects Mitochondrial Function in Osteosarcoma Cells

scientific article published on 18 September 2015

Adriamycin binding assay: a valuable chemosensitivity test in human osteosarcoma

scientific article

Alpha-lipoic Acid After Median Nerve Decompression at the Carpal Tunnel: A Randomized Controlled Trial.

scientific article published on 28 February 2017

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance.

scientific article published on 22 August 2016

Analysis of P-glycoprotein expression in osteosarcoma

scientific article published on 01 November 1995

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism

scientific article published on 03 October 2018

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

scientific article

Association of two gene polymorphisms with osteoarthritis secondary to hip dysplasia.

scientific article published in October 2002

Auto-Allo Graft Parallel Juxtaposition for Improved Neuroregeneration in Peripheral Nerve Reconstruction Based on Acellular Nerve Allografts

scientific article published on 01 September 2019

Biocompatibility of poly(D,L-lactide-co-glycolide) nanoparticles conjugated with alendronate

scientific article

Biological basis for the use of autologous bone marrow stromal cells in the treatment of congenital pseudarthrosis of the tibia

scientific article published on 10 November 2009

Biological effects of metal degradation in hip arthroplasties.

scientific article

Biomarkers of bone healing induced by a regenerative approach based on expanded bone marrow-derived mesenchymal stromal cells

scientific article published on 01 July 2019

Blocking Tumor-Educated MSC Paracrine Activity Halts Osteosarcoma Progression

scientific article published on 4 January 2017

Bone cement extracts modulate the osteoprotegerin/osteoprotegerin-ligand expression in MG63 osteoblast-like cells

scientific article

Bone regeneration and stem cells

scientific article (publication date: April 2011)

Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation

scientific article published on 26 November 2016

Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

scientific article published on 10 September 2015

Cause and effect of microenvironmental acidosis on bone metastases

scientific article published on 01 June 2019

Cell-based Assay System for Predicting Bone Regeneration in Patient Affected by Aseptic Nonunion and Treated with Platelet Rich Fibrin.

scientific article published on 19 July 2016

Change in FGF-2 circulating levels after arterial embolization in patients with bone metastases

scientific article published on 01 January 2018

Chromosome 1 aneusomy with 1p36 under-representation is related to histologic grade, DNA aneuploidy, high c-erb B-2 and loss of bcl-2 expression in ductal breast carcinoma

scientific article published on 01 October 1996

Clinical Trial of Radiotherapy After Intravenous Injection of Acridine Orange for Patients with Cancer

scientific article published in January 2018

Clinical evaluation of 104 hip resection arthroplasties after removal of a total hip prosthesis

scientific article published on 01 January 1987

Clinical relevance of Ki-67 expression in bone tumors

scientific article published on 01 February 1995

Clone heterogeneity in diploid and aneuploid breast carcinomas as detected by FISH.

scientific article

Comparative "in vitro" evaluation of the antiresorptive activity residing in four Ayurvedic medicinal plants. Hemidesmus indicus emerges for its potential in the treatment of bone loss diseases

scientific article published on 29 April 2014

Deep sepsis from Mycobacterium tuberculosis after total hip replacement. Case report

scientific article published on 01 January 1988

Differences in ion release after ceramic-on-ceramic and metal-on-metal total hip replacement. Medium-term follow-up.

scientific article published in April 2006

Do ion levels in hip resurfacing differ from metal-on-metal THA at midterm?

scientific article

Do ion levels in metal-on-metal hip resurfacing differ from those in metal-on-metal THA at long-term followup?

scientific article published on 10 April 2013

Does chronic raise of metal ion levels induce oxidative DNA damage and hypoxia-like response in patients with metal-on-metal hip resurfacing?

scientific article published on 19 October 2015

Does ion release differ between hip resurfacing and metal-on-metal THA?

scientific article published on 9 January 2008

Effect of acetabular cup design on metal ion release in two designs of metal-on-metal hip resurfacing

scientific article

Effect of calcium phosphate heparinization on the in vitro inflammatory response and osteoclastogenesis of human blood precursor cells

scientific article published on 31 May 2019

Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells

scientific article published on March 2002

Effects of activated platelet concentrates on human primary cultures of fibroblasts and osteoblasts

scientific article published in March 2005

Effects of antisense mediated inhibition of cathepsin K on human osteoclasts obtained from peripheral blood

Effects of bone cement extracts on the cell-mediated immune response

scientific article published in February 2002

Effects of hypoxia on osteogenic differentiation of mesenchymal stromal cells used as a cell therapy for avascular necrosis of the femoral head

scientific article published on 12 July 2016

Effects of osteogenic differentiation inducers on in vitro expanded adult mesenchymal stromal cells

scientific article published in October 2011

Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts

scientific article published in September 2008

Endothelial cells incubated with platelet-rich plasma express PDGF-B and ICAM-1 and induce bone marrow stromal cell migration

scientific article published in November 2009

Energy metabolism in osteoclast formation and activity

scientific article published on 30 August 2016

Enhancing osteoconduction of PLLA-based nanocomposite scaffolds for bone regeneration using different biomimetic signals to MSCs

scientific article published on 22 February 2012

Epithelioid hemangioma of bone: A unique case with multifocal metachronous bone lesions

scientific article published on 16 March 2019

Evaluation of P-glycoprotein expression in soft tissue sarcomas of the extremities

scientific article published on 01 January 1996

Evaluation of bone healing enhancement by lyophilized bone grafts supplemented with platelet gel: a standardized methodology in patients with tibial osteotomy for genu varus

scientific article published on 01 February 2006

Evaluation of mechanical properties and biological response of an alumina-forming Ni-free ferritic alloy.

scientific article

Evaluation of osteonectin as a diagnostic marker of osteogenic bone tumors

scientific article published on 01 December 1992

Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs

scientific article published on 7 March 2012

Exosome-like nanovesicles isolated from Citrus limon L. exert antioxidative effect

scientific article published on 01 January 2018

Expression Profiling of Osteosarcoma Cells Transfected with MDR1 and NEO Genes: Regulation of Cell Adhesion, Apoptosis, and Tumor Suppression-Related Genes ⬇️

scientific article published on April 1, 2003

Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome

scientific article published on 01 November 1995

Expression of cell adhesion receptors in human osteoblasts cultured on biofunctionalized poly-(epsilon-caprolactone) surfaces

article

Extracellular Nanovesicles Secreted by Human Osteosarcoma Cells Promote Angiogenesis

scientific article published on 05 June 2019

Feasibility and safety of treating non-unions in tibia, femur and humerus with autologous, expanded, bone marrow-derived mesenchymal stromal cells associated with biphasic calcium phosphate biomaterials in a multicentric, non-comparative trial.

scientific article published on 19 March 2018

Flexible polymeric ultrathin film for mesenchymal stem cell differentiation

scientific article published on 21 March 2011

Frequency and implications of chromosome 8 and 12 gains in Ewing sarcoma

scientific article published on 01 January 1998

Gene expression patterns related to osteogenic differentiation of bone marrow-derived mesenchymal stem cells during ex vivo expansion

scientific article published on June 2010

Giant cell reparative granuloma and other giant cell lesions of the bones of the hands and feet

scientific article published on 01 January 1986

Height as a risk factor for osteosarcoma.

scientific article published in June 2005

Histogenetic characterization of giant cell tumor of bone

scientific article published on 10 June 2008

Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma.

scientific article published on 23 February 2018

How do metal ion levels change over time in hip resurfacing patients? A cohort study.

scientific article published on 14 December 2014

Human bone marrow stromal cells: In vitro expansion and differentiation for bone engineering.

scientific article published on 11 September 2006

Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species

scientific article published in July 2015

Hypoxia enhances proliferation and stemness of human adipose-derived mesenchymal stem cells

scientific article

IGF2 derived from SH-SY5Y neuroblastoma cells induces the osteoclastogenesis of human monocytic precursors

Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells

scientific article published on 19 February 2016

Idiopathic and secondary osteonecrosis of the femoral head show different thrombophilic changes and normal or higher levels of platelet growth factors

scientific article published on February 2011

Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.

scientific article published on April 1996

Impairment of lysosomal activity as a therapeutic modality targeting cancer stem cells of embryonal rhabdomyosarcoma cell line RD.

scientific article

Improved osteogenic differentiation of human marrow stromal cells cultured on ion-induced chemically structured poly-epsilon-caprolactone

scientific article published on 21 November 2006

In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells

article published in 2004

In vitro evaluation of freeze-dried bone allografts combined with platelet rich plasma and human bone marrow stromal cells for tissue engineering

scientific article

In vitro models for the evaluation of angiogenic potential in bone engineering

scientific article

In vitro testing of the potential for orthopedic bone cements to cause apoptosis of osteoblast-like cells.

scientific article published in January 2002

In vivo study on the healing of bone defects treated with bone marrow stromal cells, platelet-rich plasma, and freeze-dried bone allografts, alone and in combination.

scientific article

Innovative silicate-based cements for endodontics: a study of osteoblast-like cell response

article

Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.

scientific article

Insulin receptor isoforms are differently expressed during human osteoblastogenesis

scientific article

Intracellular pH regulation in U-2 OS human osteosarcoma cells transfected with P-glycoprotein

scientific article published on January 2002

Involvement of HIF-1α activation in the doxorubicin resistance of human osteosarcoma cells

scientific article published on 15 May 2014

Ion release in patients with metal-on-metal hip bearings in total joint replacement: a comparison with metal-on-polyethylene bearings

scientific article published on 01 January 2002

Is the high superior tension technique an equivalent substitute for progressive tension sutures in postbariatric abdominoplasty? A comparison prospective study

scientific article published on 01 March 2014

Is wear debris responsible for failure in alumina-on-alumina implants?

scientific article

Long-term systemic metal distribution in patients with stainless steel spinal instrumentation: a case-control study

scientific article published in April 2015

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases

scientific article published on 30 August 2017

MET overexpression turns human primary osteoblasts into osteosarcomas.

scientific article published on May 2006

Mesenchymal progenitors expressing TRAIL induce apoptosis in sarcomas

scientific article

Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy

scientific article published on 6 September 2012

Mesenchymal stroma: Role in osteosarcoma progression.

scientific article published on 31 July 2017

Metal ion release from fracture fixation devices: a potential marker of implant failure

scientific article published in August 2008

MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31.

scientific article published on July 2013

Modulation of TGFbeta 2 levels by lamin A in U2-OS osteoblast-like cells: understanding the osteolytic process triggered by altered lamins

scientific article

Molecular basis of osteoclastogenesis induced by osteoblasts exposed to wear particles

scientific article published in May 2005

Multidrug resistance--a multiplex phenomenon

scientific article published on 01 April 1997

Multidrug-resistance (MDR) phenotype of human osteosarcoma cells evaluated by quantitative morphological and electron microscopy analyses.

scientific article published on January 1995

Multimodal transfer of MDR by exosomes in human osteosarcoma

scientific article published on 9 May 2016

Multiscale characterization of a chimeric biomimetic polypeptide for stem cell culture

article

Murine model for skeletal metastases of Ewing's sarcoma

scientific article

Neuroblastoma and bone metastases: clinical significance and prognostic value of Dickkopf 1 plasma levels

scientific article published on 14 July 2010

New Advances in the Study of Bone Tumors: A Lesson From the 3D Environment

scientific article published on 26 June 2019

New couplings, old problems: Is there a role for ceramic-on-metal hip arthroplasty?

scientific article published on 10 February 2015

Noncellular modification of Acellular Nerve Allografts for peripheral nerve reconstruction: A systematic critical review of the animal literature

scientific article published on 07 November 2018

Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells

scientific article published on 30 April 2015

Novel soybean/gelatine-based bioactive and injectable hydroxyapatite foam: material properties and cell response.

scientific article published on 14 December 2010

Nuclear matrix-bound replicational sites detected in situ by 5-bromodeoxyuridine

scientific article published on August 1992

Orthopaedic research in italy: state of the art.

scientific article published on January 2011

Orthoplastics: an evolving concept for integrated surgical care of complex limb trauma and abnormality

scientific article published on 01 February 2013

Osteoblast growth and function in porous poly epsilon -caprolactone matrices for bone repair: a preliminary study.

scientific article

Osteoblast growth and functions in porous degradable synthetic matrices for bone repair: a preliminary study

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

scientific article published on 16 March 2011

Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates

scientific article

Osteogenic properties of late adherent subpopulations of human bone marrow stromal cells

scientific article published on 27 August 2009

Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies

scientific article

P-glycoprotein expression in osteosarcoma: a basis for risk-adapted adjuvant chemotherapy.

scientific article

Paracrine inhibition of osteoblast differentiation induced by neuroblastoma cells.

scientific article published in October 2008

Partial resection of distal humerus and reconstruction using autogenous iliac bone graft

scientific article published on 01 January 1988

Photodynamic Surgery for Feline Injection-Site Sarcoma

scientific article published on 08 July 2019

Plasma levels of coagulation inhibitors, fibrinolytic markers and platelet-derived growth factor-AB in patients with failed hip prosthesis

Plasma levels of platelet-derived growth factor BB and transforming growth factor in patients with failed hip prostheses

scientific article published in February 2005

Plasma levels of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in patients with neuroblastoma

Platelet-rich plasma impairs osteoclast generation from human precursors of peripheral blood

scientific article published on 01 June 2010

Poly-epsilon-caprolactone/hydroxyapatite composites for bone regeneration: in vitro characterization and human osteoblast response

scientific article published on January 2006

Polylactic acid fibre-reinforced polycaprolactone scaffolds for bone tissue engineering.

scientific article published on 10 June 2008

Polyomavirus latency and human tumors

scientific article published in May 1994

Potassium Citrate Supplementation Decreases the Biochemical Markers of Bone Loss in a Group of Osteopenic Women: The Results of a Randomized, Double-Blind, Placebo-Controlled Pilot Study

scientific article published on 12 September 2018

Potassium citrate prevents increased osteoclastogenesis resulting from acidic conditions: Implication for the treatment of postmenopausal bone loss.

scientific article published on 17 July 2017

Potential role of tartrate-resistant acid phosphatase 5b (TRACP 5b) as a surrogate marker of late loosening in patients with total hip arthroplasty: a cohort study

scientific article published on 01 July 2010

Pre-clinical Models for Studying the Interaction Between Mesenchymal Stromal Cells and Cancer Cells and the Induction of Stemness

scientific article published on 30 April 2019

Pre-operative diagnosis of infection in total knee arthroplasty: an algorithm

scientific article published on 4 March 2009

Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin

scientific article published on 01 July 1994

Predictive factors of histological response to primary chemotherapy in Ewing's sarcoma

scientific article published in January 1998

Preparation method and growth factor content of platelet concentrate influence the osteogenic differentiation of bone marrow stromal cells

scientific article published in July 2013

Prolonged exposure to hypoxic milieu improves the osteogenic potential of adipose derived stem cells.

scientific article published in July 2015

Prominent role of RAB39A-RXRB axis in cancer development and stemness.

scientific article

Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients' bed

scientific article published on 24 October 2013

Quantitative assessment of the response of osteoblast- and macrophage-like cells to particles of Ni-free Fe-base alloys

article

Recent highlights on bone stem cells: a report from Bone Stem Cells 2009, and not only….

scientific article published on November 2010

Redundancy of autocrine loops in human osteosarcoma cells.

scientific article published on February 1999

Relevance of deep decortication and vascularization in a case of post-traumatic femoral non-union treated with grafts, platelet gel and bone marrow stromal cells

scientific article published on 24 November 2011

Resorbable Glass–Ceramic Phosphate-based Scaffolds for Bone Tissue Engineering: Synthesis, Properties, and In vitro Effects on Human Marrow Stromal Cells

scientific article published on 21 June 2010

Response of human bone marrow stromal cells to a resorbable P(2)O(5)-SiO(2)-CaO-MgO-Na(2)O-K(2)O phosphate glass ceramic for tissue engineering applications

article

Reversal of malignant phenotype in human osteosarcoma cells transduced with the alkaline phosphatase gene

scientific article

Role of PLLA plasma surface modification in the interaction with human marrow stromal cells

Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells.

scientific article published on September 2014

Sarcoma treatment in the era of molecular medicine

scientific article published on 13 October 2020

Sensitivity to implant materials in patients undergoing total hip replacement

scientific article published in May 2006

Sensitivity to implant materials in patients with total knee arthroplasties

scientific article published on 21 December 2007

Serum ion levels after ceramic-on-ceramic and metal-on-metal total hip arthroplasty: 8-year minimum follow-up

scientific article published in December 2008

Serum levels of fibroblast growth factor 2 in children with orthopedic diseases: potential role in predicting bone healing

scientific article published on 14 September 2012

Serum levels of osteoprotegerin and receptor activator of nuclear factor-kappaB ligand as markers of periprosthetic osteolysis

scientific article published in July 2006

Simultaneous paired analysis of numerical chromosomal aberrations and DNA content in osteosarcoma.

scientific article published in July 2001

Sphere-forming cell subsets with cancer stem cell properties in human musculoskeletal sarcomas

scientific article published on May 2013

Spheroid-based 3D cell cultures identify salinomycin as a promising drug for the treatment of chondrosarcoma

article

Spontaneous formation of multinucleated giant cells with bone resorbing activity by long culture of human peripheral blood CD14-positive monocytes in vitro

scientific article published on 01 February 2010

Sustained autocrine induction and impaired negative feedback of osteoclastogenesis in CD14(+) cells of giant cell tumor of bone.

scientific article

Systemic cross-linked N-terminal telopeptide and procollagen I C-terminal extension peptide as markers of bone turnover after total hip arthroplasty

scientific article published in April 2005

The Combined Use of Mesenchymal Stromal Cells and Scaffolds for Bone Repair ⬇️

scientific article published on January 1, 2012

The Effects of Systemic and Local Acidosis on Insulin Resistance and Signaling ⬇️

scientific article published on 30 December 2018

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

scientific article

The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro

scientific article

The effect of irradiation modification and RGD sequence adsorption on the response of human osteoblasts to polycaprolactone

scientific article

The effect of perineurotomy on nerve regeneration in diabetic rats: how to export it to the clinical setting?

scientific article published in June 2013

The effect of poly(d,l-lactide-co-glycolide)-alendronate conjugate nanoparticles on human osteoclast precursors

scientific article published on 20 July 2011

The expression of Met/hepatocyte growth factor receptor gene in giant cell tumors of bone and other benign musculoskeletal tumors

scientific article published on 01 August 2000

The expression of P-glycoprotein is causally related to a less aggressive phenotype in human osteosarcoma cells.

scientific article

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

scientific article

The influence of alumina and ultra-high molecular weight polyethylene particles on osteoblast-osteoclast cooperation.

scientific article published in August 2004

The natural compound Alizarin as an osteotropic drug for the treatment of bone tumors

scientific article

The performance of poly-epsilon-caprolactone scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4.

scientific article published on 18 March 2007

The potential role of metal ion release as a marker of loosening in patients with total knee replacement: a cohort study

scientific article published on 01 May 2010

The role of hydroxyapatite as solid signal on performance of PCL porous scaffolds for bone tissue regeneration

scientific article

Therapeutic implications of tumor interstitial acidification.

scientific article published on 7 February 2017

Translational research of photodynamic therapy with acridine orange which targets cancer acidity

scientific article published in January 2012

Treatment for long bone metastases based on a systematic literature review

scientific article published on 20 September 2016

Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion.

scientific article

V-ATPase as an effective therapeutic target for sarcomas

scientific article published on January 2014

V-ATPase is a candidate therapeutic target for Ewing sarcoma

scientific article published on 8 April 2013

Validation of Suitable Housekeeping Genes for the Normalization of mRNA Expression for Studying Tumor Acidosis

article

α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors

scientific article published on 19 February 2019

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