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List of works by Stefano Govoni

Acetylcholinesterase inhibitors: novel activities of old molecules.

scientific article published in October 2004

Activation of the JAK/STAT pathway leads to proliferation of ST14A central nervous system progenitor cells

scientific article published on September 1996

Activity of alpha-secretase as the common final effector of protein kinase C-dependent and -independent modulation of amyloid precursor protein metabolism

scientific article published on 01 June 1999

Acute beta-amyloid administration disrupts the cholinergic control of dopamine release in the nucleus accumbens

scientific article published on 20 June 2007

Age related differences in dopamine-stimulated adenylate cyclase sensitivity to "in vivo" chronic ethanol treatment

scientific article published in July 1984

Age-related decline in RACK-1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone.

scientific article published on 17 November 2004

Alcohol differentially affects noradrenergic and purinergic responses in the bisected rat vas deferens

scientific article published on 01 October 2000

Alzheimer's disease: facing the biological complexity to treat the disease.

scientific article published in October 2004

Alzheimer's disease: new diagnostic and therapeutic tools

scientific article published on 13 August 2008

Amyloid precursor protein metabolism in fibroblasts from individuals with one, two or three copies of the amyloid precursor protein (APP) gene

scientific article published in March 1999

Antiradical activity of water soluble components in common diet vegetables

scientific article published in February 2002

Are Hsp70 protein expression and genetic polymorphism implicated in multiple sclerosis inflammation?

scientific article published on 16 January 2014

Association of the estrogen receptor alpha gene polymorphisms with sporadic Alzheimer's disease.

scientific article published in November 1999

Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells

scientific article

Awakenings and awareness recovery in disorders of consciousness: is there a role for drugs?

scientific article published on August 2010

AβPP intracellular C-terminal domain function is related to its degradation processes

scientific article published in January 2012

Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus.

scientific article published on 27 July 2012

Beta-amyloid short- and long-term synaptic entanglement

scientific article published on 22 November 2018

Bladder instability: a re-appraisal of classical experimental approaches and development of new therapeutic strategies.

scientific article

Calcium antagonists inhibit met-enkephalin immunoreactive material release: in vitro and ex vivo experiments

scientific article published on 01 January 1990

Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families

scientific article published in July 1998

Capillary electrophoresis studies on the aggregation process of beta-amyloid 1-42 and 1-40 peptides

scientific article published on 01 October 2004

Changes in beta amyloid precursor protein secretion associated with the proliferative status of CNS derived progenitor cells

scientific article published on July 1996

Changes of beta-endorphin and Met-enkephalin content in the hypothalamus-pituitary axis induced by aging.

scientific article published in January 1983

Characterization and distribution of protein kinase C isoforms in human skin fibroblasts

scientific article published on 01 October 1994

Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells

scientific article published in August 2003

Chronic alcohol intake modifies phorbol ester binding in selected rat brain areas

scientific article published on 01 March 1989

Chronic low doses of ethanol affect brain protein kinase C and ultrasonic calls in rats

scientific article

Clinical correlates of apolipoprotein E in Alzheimer's disease

scholarly article by G. B. Frisoni et al published October 1996 in Annals of Neurology

Clinical pharmacokinetics of morphine and its metabolites during morphine dose titration for chronic cancer pain

scientific article published on June 2014

Cognition enhancers between treating and doping the mind

scientific article

Concomitant regulation of hippocampal calcium antagonist receptors and calcium uptake by substance P

scientific article published on 01 May 1987

Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression.

scientific article published on 07 February 2013

Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease

scientific article

Conformationally altered p53: a novel Alzheimer's disease marker?

scientific article published on 7 August 2007

Conformationally altered p53: a putative peripheral marker for Alzheimer's disease.

scientific article published on 06 March 2008

Cytoprotective response induced by electromagnetic stimulation on SH-SY5Y human neuroblastoma cell line

scientific article published on 5 July 2011

Cytosolic hippocampal PKC and aging: correlation with discrimination performance

scientific article published in March 1998

Dehydroepiandrosterone and the relationship with aging and memory: a possible link with protein kinase C functional machinery

scientific article published on 01 November 2001

Depression and antidepressants: molecular and cellular aspects.

scientific article published on 12 June 2009

Different presynaptic nicotinic receptor subtypes modulate in vivo and in vitro the release of glycine in the rat hippocampus

scientific article published on 5 July 2011

Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein.

scientific article published on July 2004

Differential isoform-specific regulation of calcium-independent protein kinase C in rat cerebral cortex

scientific article published in August 1996

Discovery of small peptides derived from embryonic lethal abnormal vision proteins structure showing RNA-stabilizing properties.

scientific article

Do we need pharmacogenetics to personalize antidepressant therapy?

scientific article published on 28 December 2012

Dopamine uptake is differentially regulated in rat striatum and nucleus accumbens

scientific article published in July 1985

Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus

scientific article

ELAV-GAP43 pathway activation following combined exposure to cocaine and stress

scientific article

Effect of acute alcohol on ischemia-induced glutamate release and brain damage

scientific article

Effect of calcium entry blockade on ethanol-induced changes in bronchomotor tone

scientific article published on January 1985

Effect of desmethyldiazepam and chlordesmethyldiazepam on 3?,5?-cyclic guanosine monophosphate levels in rat cerebellum ⬇️

scientific article published on November 24, 1976

Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells.

scientific article published on August 1997

Effect of in vivo and in vitro ethanol on adrenergic and purinergic responses of the bisected rat vas deferens to low and high frequency pulses.

scientific article published in August 2001

Effects of chronic low-dose ethanol intake on sexual behavior in rats

scientific article published on 01 August 1998

Effects of hormone therapy on brain morphology of healthy postmenopausal women: a Voxel-based morphometry study.

scientific article published in July 2006

Emerging targets for the pharmacology of learning and memory.

scientific article published on August 2004

Energy metabolism inhibition impairs amyloid precursor protein secretion from Alzheimer's fibroblasts.

scientific article published in March 1999

Estrogen receptor alpha and APOEepsilon4 polymorphisms interact to increase risk for sporadic AD in Italian females

scientific article published in June 2006

Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain

scientific article

Expression and phosphorylation of delta-CaM kinase II in cultured Alzheimer fibroblasts

scientific article

Expression and regulation of calcium-independent protein kinase C in NG 108-15 cell differentiation.

scientific article published in September 1994

Familial migraine with aura: association study with 5-HT1B/1D, 5-HT2C, and hSERT polymorphisms

scientific article published in April 2004

Fibroblasts from Alzheimer's disease donors do not differ from controls in response to heat shock

scientific article published on 01 October 1998

Functional mapping of the promoter region of the GNB2L1 human gene coding for RACK1 scaffold protein

scientific article

Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease.

scientific article

Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain

scientific article published on 19 May 2013

High interleukin-10 production is associated with low antibody response to influenza vaccination in the elderly.

scientific article published on 17 May 2006

Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survival

scientific article

How and why to screen for CYP2D6 interindividual variability in patients under pharmacological treatments

scientific article published on March 2010

Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients.

scientific article

Identification of peptides with ELAV-like mRNA-stabilizing effect: an integrated in vitro/in silico approach

scientific article published on 11 April 2013

Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

scientific article published on 29 May 2020

In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee

scientific article published in March 2004

Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory

scientific journal article

Increased natural killer cell cytotoxicity in Alzheimer's disease may involve protein kinase C dysregulation

scientific article published in May 1998

Influence of COMT Val158Met polymorphism on Alzheimer's disease and mild cognitive impairment in Italian patients

scientific article

Influence of different anaesthetics on extracellular aminoacids in rat brain

scientific article published in September 2000

Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution

scientific article

Inositol 1,4,5-trisphosphate receptor and ryanodine receptor in the aging brain of Wistar rats

scientific article

Intrathecal baclofen in patients with persistent vegetative state: 2 hypotheses.

scientific article

Ischemia-induced glutamate release in rat frontoparietal cortex after chronic alcohol and withdrawal

scientific article published in July 2002

Lead contamination in the mallard (Anas platyrhynchos) in Italy

scientific article published in May 1996

Members of the JAK/STAT proteins are expressed and regulated during development in the mammalian forebrain

scientific article published in November 1998

Menopause and estrogen deficiency as a risk factor in dementing illness: hypothesis on the biological basis.

scientific article

Modulation of Rack-1/PKCβII signalling by soluble AβPPα in SH-SY5Y cells

scientific article published on September 2013

Modulation of rat skeletal muscle chloride channels by activators and inhibitors of protein kinase C.

scientific article published in June 1991

N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands

scientific article published in October 1998

NGF and heart: Is there a role in heart disease?

scientific article published on 30 December 2010

Neuronal control of brain microvessel function

scientific article published on April 1985

Neurotensin effect on dopamine release and calcium transport in rat striatum: interactions with diphenylalkylamine calcium antagonists

scientific article published in March 1986

Nicotinic component of galantamine in the regulation of amyloid precursor protein processing

scientific article published on December 2006

Non-virally mediated gene transfer into human central nervous system precursor cells.

scientific article

Novel approaches to the post-myocardial infarction/heart failure neural remodeling.

scientific article published on September 2014

Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives

scientific article published in October 1996

Over-expression of amyloid precursor protein in HEK cells alters p53 conformational state and protects against doxorubicin

scientific article

Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients

scientific article published on October 1997

PKC activity in rat C6 glioma cells: changes associated with cell cycle and simvastatin treatment

scientific article published on 01 April 1994

PKC translocation in rat brain cortex is promoted in vivo and in vitro by alpha-glycerylphosphorylcholine, a cognition-enhancing drug

scientific article published on 01 September 1993

PKCbetaII/HuR/VEGF: A new molecular cascade in retinal pericytes for the regulation of VEGF gene expression

scientific article published on 5 December 2007

Pentraxins and Alzheimer's disease: at the interface between biomarkers and pharmacological targets.

scientific article published on 15 December 2011

Peripheral cells as an investigational tool for Alzheimer's disease.

scientific article

Pharmacogenetics and pharmagenomics, trends in normal and pathological aging studies: focus on p53.

scientific article published in January 2008

Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and/or transcriptional role--relevance for Alzheimer pathology

scientific article

Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: the potential involvement of the RNA-binding protein HuR.

scientific article published in January 2008

Posttranscriptional regulation of SOD1 gene expression under oxidative stress: Potential role of ELAV proteins in sporadic ALS.

scientific article published on 20 August 2013

Protecting the retinal neurons from glaucoma: lowering ocular pressure is not enough

scientific article published on 14 March 2012

Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients

scientific article

Rationalizing a pharmacological intervention on the amyloid precursor protein metabolism.

scientific article

Recent advances in the pharmacology of Ca2+ and K+ channels

scientific article published on 01 January 1995

Recruitment of casein kinase 2 is involved in AbetaPP processing following cholinergic stimulation

scientific article published on January 2010

Regulation of protein kinase C in NG108-15 cell differentiation

scientific article published on May 1994

Role of protein kinase Calpha in the regulated secretion of the amyloid precursor protein

scientific article

STAT signalling in the mature and aging brain

scientific article published in July 2000

Selective impairment of noradrenergic transmission in the bisected rat vas deferens following photochemically-induced cerebral ischaemia

scientific article published on 27 November 2006

Senescence of the brain: focus on cognitive kinases.

scientific article published on January 2010

Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein

scientific article published in September 2001

Soluble amyloid beta1-42 reduces dopamine levels in rat prefrontal cortex: relationship to nitric oxide.

scientific article

Soluble beta amyloid(1-42): a critical player in producing behavioural and biochemical changes evoking depressive-related state?

scientific article

Specific inhibitory effect of amyloid-beta on presynaptic muscarinic receptor subtypes modulating neurotransmitter release in the rat nucleus accumbens

scientific article

Specific neuromodulatory actions of amyloid-beta on dopamine release in rat nucleus accumbens and caudate putamen

scientific article

Specific role for protein kinase C alpha in the constitutive and regulated secretion of amyloid precursor protein in human skin fibroblasts

scientific article published on January 1998

The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells

scientific article published on 3 May 2013

The Cycloxygenase-2 inhibitor SC58236 is neuroprotective in an in vivo model of focal ischemia in the rat.

scientific article published in May 2001

The PKCbeta/HuR/VEGF pathway in diabetic retinopathy.

scientific article published on July 2010

The Peptidyl-prolyl Isomerase Pin1 in Neuronal Signaling: from Neurodevelopment to Neurodegeneration

scientific article published on 21 October 2020

The aging brain, a key target for the future: the protein kinase C involvement.

scientific article published on 3 May 2007

The beta-oxidation of arachidonic acid and the synthesis of docosahexaenoic acid are selectively and consistently altered in skin fibroblasts from three Zellweger patients versus X-adrenoleukodystrophy, Alzheimer and control subjects

scientific article published on 01 July 1998

The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins

scientific article published on 10 September 2011

The expanding universe of neurotrophic factors: therapeutic potential in aging and age-associated disorders.

scientific article published on January 2010

The pharmacology of amyloid precursor protein processing.

scientific article

The role of anchoring protein RACK1 in PKC activation in the ageing rat brain

scientific article published on September 1997

Unfolded p53 in blood as a predictive signature signature of the transition from mild cognitive impairment to Alzheimer's disease.

scientific article

Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53.

scientific article published on 13 January 2009

Wild type but not mutant APP is involved in protective adaptive responses against oxidants

article

Zyxin is a novel target for β-amyloid peptide: characterization of its role in Alzheimer's pathogenesis

scientific article published on 13 February 2013

p53 at the crossroads between cancer and neurodegeneration

scientific article published on 03 March 2012

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