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List of works by Françoise Van Bambeke

2-Aminobenzothiazole derivatives: search for new antifungal agents

scientific article published on 9 April 2013

A combined pharmacodynamic quantitative and qualitative model reveals the potent activity of daptomycin and delafloxacin against Staphylococcus aureus biofilms.

scientific article published on 09 April 2013

A combined phenotypic and genotypic method for the detection of Mex efflux pumps in Pseudomonas aeruginosa

scientific article published on 08 February 2007

ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions

scientific article published on May 2011

Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin.

scientific article

Acquired resistance to macrolides in Pseudomonas aeruginosa from cystic fibrosis patients

scientific article published on 19 May 2017

Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter.

scientific article

Activities of Combinations of Antistaphylococcal Antibiotics with Fusidic Acid against Staphylococcal Biofilms in Static and Dynamic Models

scientific article published on 26 June 2018

Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes.

scientific article

Activities of antistaphylococcal antibiotics towards the extracellular and intraphagocytic forms of Staphylococcus aureus isolates from a patient with persistent bacteraemia and endocarditis

scientific article published in August 2008

Activity of Antibiotics against Pseudomonas aeruginosa in an In Vitro Model of Biofilms in the Context of Cystic Fibrosis: Influence of the Culture Medium

scientific article published on 24 March 2020

Activity of Antibiotics against Staphylococcus aureus in an In Vitro Model of Biofilms in the Context of Cystic Fibrosis: Influence of the Culture Medium

scientific article published on 24 June 2019

Activity of beta-lactams (ampicillin, meropenem), gentamicin, azithromycin and moxifloxacin against intracellular Listeria monocytogenes in a 24 h THP-1 human macrophage model

scientific article published on 13 March 2003

Activity of ceftaroline against extracellular (broth) and intracellular (THP-1 monocytes) forms of methicillin-resistant Staphylococcus aureus: comparison with vancomycin, linezolid and daptomycin

scientific article published on 27 November 2012

Activity of finafloxacin, a novel fluoroquinolone with increased activity at acid pH, towards extracellular and intracellular Staphylococcus aureus, Listeria monocytogenes and Legionella pneumophila

scientific article published on 18 May 2011

Activity of fusidic acid against extracellular and intracellular Staphylococcus aureus: influence of pH and comparison with linezolid and clindamycin.

scientific article published on June 2011

Activity of moxifloxacin against intracellular community-acquired methicillin-resistant Staphylococcus aureus: comparison with clindamycin, linezolid and co-trimoxazole and attempt at defining an intracellular susceptibility breakpoint

scientific article published on 23 December 2010

Activity of quinupristin/dalfopristin against extracellular and intracellular Staphylococcus aureus with various resistance phenotypes

scientific article published on 8 April 2010

Activity of three {beta}-lactams (ertapenem, meropenem and ampicillin) against intraphagocytic Listeria monocytogenes and Staphylococcus aureus.

scientific article published on 28 April 2005

Alterations in membrane permeability induced by aminoglycoside antibiotics: studies on liposomes and cultured cells

scientific article published on 01 October 1993

Aminoglycoside antibiotics induce aggregation but not fusion of negatively-charged liposomes

scientific article published on 01 April 1995

Aminoglycoside antibiotics prevent the formation of non-bilayer structures in negatively-charged membranes. Comparative studies using fusogenic (bis(β-diethylaminoethylether)hexestrol) and aggregating (spermine) agents

scientific article published on 01 March 1996

Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC)

scientific article

Anidulafungin increases the antibacterial activity of tigecycline in polymicrobial Candida albicans/Staphylococcus aureus biofilms on intraperitoneally implanted foreign bodies

scholarly article by Ona Rogiers et al published 13 July 2018 in Journal of Antimicrobial Chemotherapy

Antibiotic activity against naive and induced Streptococcus pneumoniae biofilms in an in vitro pharmacodynamic model

scientific article

Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data

scientific article

Antibiotic efflux pumps in eukaryotic cells: occurrence and impact on antibiotic cellular pharmacokinetics, pharmacodynamics and toxicodynamics

scientific article published on April 14, 2003

Antibiotic efflux pumps in prokaryotic cells: occurrence, impact on resistance and strategies for the future of antimicrobial therapy

scientific article published on April 14, 2003

Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients in Northern Europe.

scientific article published on 29 August 2016

Antimicrobial susceptibility of Streptococcus pneumoniae isolates from vaccinated and non-vaccinated patients with a clinically confirmed diagnosis of community-acquired pneumonia in Belgium

article

Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation

scientific article

Avibactam confers susceptibility to a large proportion of ceftazidime-resistantPseudomonas aeruginosaisolates recovered from cystic fibrosis patients

scientific article published on 14 January 2015

Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages

scientific article published on November 2002

Cellular accumulation and activity of quinolones in ciprofloxacin-resistant J774 macrophages

scientific article

Cellular accumulation and pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel fluoroketolide, against Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages

scientific article

Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages.

scientific article

Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila

scientific article

Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin

scientific article published on 21 May 2012

Cellular pharmacokinetics and intracellular activity of gepotidacin against Staphylococcus aureus with different resistance phenotypes in models of cultured phagocytic cells

scientific article published on 22 January 2018

Cellular pharmacokinetics and intracellular activity of the novel peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus laboratory and clinical strains with various resistance phenotypes: studies with human THP-1 monocytes and J774 m

scientific article published on 13 July 2015

Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines

scientific article published on 16 September 2009

Cellular pharmacokinetics and pharmacodynamics of the glycopeptide antibiotic oritavancin (LY333328) in a model of J774 mouse macrophages.

scientific article published on August 2004

Cellular pharmacokinetics of telavancin, a novel lipoglycopeptide antibiotic, and analysis of lysosomal changes in cultured eukaryotic cells (J774 mouse macrophages and rat embryonic fibroblasts).

scientific article published on 27 March 2008

Cellular pharmacokinetics of the novel biaryloxazolidinone radezolid in phagocytic cells: studies with macrophages and polymorphonuclear neutrophils.

scientific article published on 12 April 2010

Characterisation of a collection of Streptococcus pneumoniae isolates from patients suffering from acute exacerbations of chronic bronchitis: In vitro susceptibility to antibiotics and biofilm formation in relation to antibiotic efflux and serotypes/

scientific article published on 07 July 2014

Characterization of Abcc4 gene amplification in stepwise-selected mouse J774 macrophages resistant to the topoisomerase II inhibitor ciprofloxacin

scientific article

Combined effect of pH and concentration on the activities of gentamicin and oxacillin against Staphylococcus aureus in pharmacodynamic models of extracellular and intracellular infections

scientific article published on 12 January 2007

Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages.

scientific article published on 24 February 2005

Comparative in vitro antimicrobial potency, stability, colouration and dissolution time of generics versus innovator of meropenem in Europe

scientific article published on 19 October 2019

Comparative intracellular (THP-1 macrophage) and extracellular activities of beta-lactams, azithromycin, gentamicin, and fluoroquinolones against Listeria monocytogenes at clinically relevant concentrations

scientific article

Comparison of the antibiotic activities of Daptomycin, Vancomycin, and the investigational Fluoroquinolone Delafloxacin against biofilms from Staphylococcus aureus clinical isolates.

scientific article

Contrasting Effects of Acidic pH on the Extracellular and Intracellular Activities of the Anti-Gram-Positive Fluoroquinolones Moxifloxacin and Delafloxacin against Staphylococcus aureus

scientific article published on December 6, 2010

Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes

scientific article

Cooperation between prokaryotic (Lde) and eukaryotic (MRP) efflux transporters in J774 macrophages infected with Listeria monocytogenes: studies with ciprofloxacin and moxifloxacin

scientific article

Correlation between cytotoxicity induced by Pseudomonas aeruginosa clinical isolates from acute infections and IL-1β secretion in a model of human THP-1 monocytes.

scientific article

DD-ligases as a potential target for antibiotics: past, present and future.

scientific article published on January 2009

Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy

scientific article

Determination of optimal loading and maintenance doses for continuous infusion of vancomycin in critically ill patients: Population pharmacokinetic modelling and simulations for improved dosing schemes

scientific article published on 07 October 2019

Determining β-lactam exposure threshold to suppress resistance development in Gram-negative bacteria

scientific article published on 31 January 2017

Development and validation of a high performance liquid chromatography assay for the determination of temocillin in serum of haemodialysis patients

scientific article published on 12 December 2013

Dynamics and Structural Changes Induced by ATP Binding in SAV1866, a Bacterial ABC Exporter

scientific article published on 11 November 2010

Editorial Commentary: Colistin and a New Paradigm in Drug Development.

scientific article published on 25 November 2015

Editorial [Hot Topic: ABC Transporters: Role in Modulation of Drug Pharmacokinetics and in Physiopathology and Therapeutic Perspectives (Guest Editor: Francoise Van Bambeke)]

scientific article published on 01 May 2011

Efflux of novel quinolones in contemporary Streptococcus pneumoniae isolates from community-acquired pneumonia

scientific article published on 28 January 2011

Evaluation of the extracellular and intracellular activities (human THP-1 macrophages) of telavancin versus vancomycin against methicillin-susceptible, methicillin-resistant, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus

scientific article published on 24 October 2006

Experimental and Conformational Analyses of Interactions between Butenafine and Lipids

scientific article published on December 1, 2001

Fluoroquinolones induce the expression of patA and patB, which encode ABC efflux pumps in Streptococcus pneumoniae.

scientific article published on 13 August 2010

Gentamicin-induced apoptosis in LLC-PK1 cells: involvement of lysosomes and mitochondria

scientific article published in August 2005

Glycopeptides in clinical development: pharmacological profile and clinical perspectives.

scientific article published in October 2004

High-level resistance to meropenem in clinical isolates of Pseudomonas aeruginosa in the absence of carbapenemases: role of active efflux and porin alterations.

scientific article published on 19 October 2016

Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation

scientific article published on October 1996

Impairment of growth of Listeria monocytogenes in THP-1 macrophages by granulocyte macrophage colony-stimulating factor: release of tumor necrosis factor-alpha and nitric oxide

scientific article

In Vitro Models for the Study of the Intracellular Activity of Antibiotics.

scientific article published on January 2016

In vivo development of antimicrobial resistance in Pseudomonas aeruginosa strains isolated from the lower respiratory tract of Intensive Care Unit patients with nosocomial pneumonia and receiving antipseudomonal therapy

scientific article published on December 2010

Increase of efflux-mediated resistance in Pseudomonas aeruginosa during antibiotic treatment in patients suffering from nosocomial pneumonia

scientific article published on 26 November 2015

Increased Azithromycin Susceptibility of Multidrug-Resistant Gram-Negative Bacteria on RPMI-1640 Agar Assessed by Disk Diffusion Testing

scientific article published on 29 April 2020

Increased susceptibility of Pseudomonas aeruginosa to macrolides and ketolides in eukaryotic cell culture media and biological fluids due to decreased expression of oprM and increased outer-membrane permeability

scientific article published on 9 May 2012

Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus

scientific article published on 14 April 2003

Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages.

scientific article

Inhibition of TNF-alpha production in THP-1 macrophages by glatiramer acetate does not alter their susceptibility to infection by Listeria monocytogenes and does not impair the efficacy of ampicillin or moxifloxacin against intracellular bacteria

scientific article

Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation

scientific article published on 13 July 2016

Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity

scientific article published on 01 October 1996

Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies.

scientific article published on October 1996

Interactions of Macrolide Antibiotics (Erythromycin A, Roxithromycin, Erythromycylamine [Dirithromycin], and Azithromycin) with Phospholipids: Computer-Aided Conformational Analysis and Studies on Acellular and Cell Culture Models

article

Interactions of ciprofloxacin with DPPC and DPPG: fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis

scientific article published on 6 September 2008

Interactions of oritavancin, a new lipoglycopeptide derived from vancomycin, with phospholipid bilayers: Effect on membrane permeability and nanoscale lipid membrane organization.

scientific article

Interactions of oritavancin, a new semi-synthetic lipoglycopeptide, with lipids extracted from Staphylococcus aureus.

scientific article published on 23 June 2010

Intra- and extracellular activities of dicloxacillin against Staphylococcus aureus in vivo and in vitro.

scientific article

Intra- and extracellular activity of linezolid against Staphylococcus aureus in vivo and in vitro

scientific article published on 7 March 2010

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

scientific article published on 04 May 2020

Intracellular accumulation and activity of ampicillin used as free drug and as its phthalimidomethyl or pivaloyloxymethyl ester (pivampicillin) against Listeria monocytogenes in J774 macrophages

scientific article published on 12 September 2003

Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-pheno

scientific article published on 02 February 2009

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

scientific article published on 9 June 2010

Intracellular forms of menadione-dependent small-colony variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to β-lactams in a THP-1 cell model due to cooperation between vacuolar acidic pH and oxidant species

scientific article

Intracellular pharmacodynamics of antibiotics.

scientific article published on September 2003

Investigation of unbound colistin A and B in clinical samples using a mass spectrometry method

scientific article published on 02 November 2018

Isolation and 2-D-DIGE proteomic analysis of intracellular and extracellular forms of Listeria monocytogenes

scientific article

Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections

scientific article published on 01 February 2008

Lipoglycopeptide Antibacterial Agents in Gram-Positive Infections: A Comparative Review

scientific article

Loss of activity of ceftazidime-avibactam due to MexAB-OprM efflux and overproduction of AmpC cephalosporinase in Pseudomonas aeruginosa isolated from patients suffering from cystic fibrosis

scientific article published on 03 August 2018

Lysosomal alterations induced in cultured rat fibroblasts by long-term exposure to low concentrations of azithromycin

scientific article published on 01 December 1998

Macrophage killing of bacterial and fungal pathogens is not inhibited by intense intracellular accumulation of the lipoglycopeptide antibiotic oritavancin

scientific article

Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic

scientific article published on 16 January 2017

Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus

scientific article published on 01 December 2002

Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically-relevant Concentrations in cultured Human HL-60 promyelocytes and THP-1 monocytes

scientific article published on 20 December 2017

Mixed-lipid storage disorder induced in macrophages and fibroblasts by oritavancin (LY333328), a new glycopeptide antibiotic with exceptional cellular accumulation

scientific article

Modelled target attainment after meropenem infusion in patients with severe nosocomial pneumonia: the PROMESSE study

scientific article published on 12 September 2014

Modulating antibiotic activity towards respiratory bacterial pathogens by co-medications: a multi-target approach

scientific article published on 16 April 2016

Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of Streptococcus pneumoniae naive and induced biofilms

scientific article published on 23 February 2015

Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells.

scientific article published on 4 June 2007

Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin.

scientific article published on 17 September 2011

Modulation of the in vitro activity of lysosomal phospholipase A1 by membrane lipids

scientific article published in January 2005

Molecular Analysis of Rising Fluoroquinolone Resistance in Belgian Non-Invasive Streptococcus pneumoniae Isolates (1995-2014)

scientific article

Molecular models of human P-glycoprotein in two different catalytic states

scientific article

New amphiphilic neamine derivatives active against resistant Pseudomonas aeruginosa and their interactions with lipopolysaccharides

scientific article

Optimizing β-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?

scientific article published on 2 June 2017

Passive diffusion of polymeric surfactants across lipid bilayers

scientific article published on 31 March 2007

Penicillin-binding proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity of Listeria monocytogenes

scientific article

Pharmacodynamic Evaluation of the Intracellular Activity of Antibiotics towards Pseudomonas aeruginosa PAO1 in a Model of THP-1 Human Monocytes

scientific article published on March 11, 2013

Pharmacodynamic evaluation of the activity of antibiotics against hemin- and menadione-dependent small-colony variants of Staphylococcus aureus in models of extracellular (broth) and intracellular (THP-1 monocytes) infections

scientific article published on 7 May 2012

Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa

scientific article published on 30 January 2017

Pharmacological characterization of 7-(4-(Piperazin-1-yl)) ciprofloxacin derivatives: antibacterial activity, cellular accumulation, susceptibility to efflux transporters, and intracellular activity

scientific article published on 5 December 2013

Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment.

scientific article published in January 2003

Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model

scientific article published on 08 September 2009

Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: insight into the mechanism of ligand migration and binding sites.

scientific article

Prolonged inhibition and incomplete recovery of mitochondrial function in oxazolidinone-treated megakaryoblastic cell lines

scientific article published on 30 July 2019

Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium.

scientific article published on 31 January 2007

Quantitative analysis of gentamicin, azithromycin, telithromycin, ciprofloxacin, moxifloxacin, and oritavancin (LY333328) activities against intracellular Staphylococcus aureus in mouse J774 macrophages

scientific article

Quinolones in 2005: an update.

scientific article

RX-P873, a Novel Protein Synthesis Inhibitor, Accumulates in Human THP-1 Monocytes and Is Active against Intracellular Infections by Gram-Positive (Staphylococcus aureus) and Gram-Negative (Pseudomonas aeruginosa) Bacteria

scientific article published on 26 May 2015

Renaissance of antibiotics against difficult infections: Focus on oritavancin and new ketolides and quinolones

scientific article

Restoration of susceptibility of intracellular methicillin-resistant Staphylococcus aureus to beta-lactams: comparison of strains, cells, and antibiotics.

scientific article published on 2 June 2008

Restoration of susceptibility of methicillin-resistant Staphylococcus aureus to beta-lactam antibiotics by acidic pH: role of penicillin-binding protein PBP 2a.

scientific article published on 12 March 2008

Reviving old antibiotics

scientific article

Role of MexAB-OprM in intrinsic resistance of Pseudomonas aeruginosa to temocillin and impact on the susceptibility of strains isolated from patients suffering from cystic fibrosis

scientific article published on 03 January 2012

Role of acidic pH in the susceptibility of intraphagocytic methicillin-resistant Staphylococcus aureus strains to meropenem and cloxacillin

scientific article published on 16 February 2007

Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic

scientific article published on 23 July 2011

Role of rsbU and staphyloxanthin in phagocytosis and intracellular growth of Staphylococcus aureus in human macrophages and endothelial cells

scientific article published on November 2009

Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluoroquinolones and other antibacterial classes

scientific article (publication date: 2009)

Salicylidene Acylhydrazides and Hydroxyquinolines Act as Inhibitors of Type Three Secretion Systems in Pseudomonas aeruginosa by Distinct Mechanisms.

scientific article published on 10 April 2017

Selection of quinolone resistance in Streptococcus pneumoniae exposed in vitro to subinhibitory drug concentrations

scientific article published on 10 August 2007

Study of macrophage functions in murine J774 cells and human activated THP-1 cells exposed to oritavancin, a lipoglycopeptide with high cellular accumulation

scientific article published on 21 January 2014

Synergistic activity between an antimicrobial polyacrylamide and daptomycin versus Staphylococcus aureus biofilm

scientific article published on 5 May 2016

Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and β-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms.

scientific article published on 16 December 2017

Synthesis and biological evaluation of 2-mercapto-1,3-benzothiazole derivatives with potential antimicrobial activity

scientific article published in October 2009

Targeting the Type Three Secretion System in Pseudomonas aeruginosa

scientific article published on 22 June 2016

Temocillin dosing in haemodialysis patients based on population pharmacokinetics of total and unbound concentrations and Monte Carlo simulations

scientific article published on 01 June 2018

Temocillin plasma and pancreatic tissue concentrations in a critically ill patient with septic shock

scientific article published on 01 May 2019

The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase.

scientific article

The role of solithromycin in the management of bacterial community-acquired pneumonia

scientific article published on 5 February 2016

Thrice-weekly temocillin administered after each dialysis session is appropriate for the treatment of serious Gram-negative infections in haemodialysis patients

scientific article

Validation of a HPLC-MS/MS assay for the determination of total and unbound concentration of temocillin in human serum

scientific article published on 21 February 2015

Water-soluble amphotericin B-polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects.

scientific article published on 16 December 2005

[Pharmacodynamics of antibiotics in CSF: principles and consequences (predictive factors of efficacy)].

scientific article published on 4 June 2009