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List of works by Caroline M Nievergelt

A candidate gene study of CYP19 (aromatase) and male sexual orientation.

scientific article

A genomewide scan of male sexual orientation

scientific article

A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function

article

A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

scientific article published in 2022

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

scientific article published on 27 November 2017

A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response

scientific article

APOEε4 and slow wave sleep in older adults

scientific article published on 25 January 2018

Admixture mapping as a gene discovery approach for complex human traits and diseases

scientific article

Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis.

scientific article published on 10 September 2009

Agreement between self and psychiatrist reporting of suicidal ideation at a Veterans Administration psychiatric emergency clinic

scientific article published on 13 August 2018

An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

scientific article published on 14 March 2020

Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling

scientific article published on 05 April 2016

Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts

scientific article published on 01 June 2020

Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

article

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

scientific article published on 31 May 2018

Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial

scientific article published on October 2007

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

scientific article published on 02 October 2019

Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk

scientific article

Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines

scientific article

Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.

scientific article published on 9 November 2017

Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines

scientific article published on 9 September 2015

Association of Race and Major Adverse Cardiac Events (MACE): The Atherosclerosis Risk in Communities (ARIC) Cohort

scientific article published on 21 March 2020

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

scientific article published on 16 March 2020

Associations of Genetically Determined Continental Ancestry With CD4+ Count and Plasma HIV-1 RNA Beyond Self-Reported Race and Ethnicity.

scientific article published on 3 November 2015

Associations of PER3 and RORA Circadian Gene Polymorphisms and Depressive Symptoms in Older Adults

scientific article

Author Correction: A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function

scientific article published on 14 February 2020

Autonomic and hemodynamic origins of pre-hypertension: central role of heredity

scientific article

Biogeographic Ancestry in the African Descent and Glaucoma Evaluation Study (ADAGES): Association With Corneal and Optic Nerve Structure

scientific article

Biological profiling of plasma neuropeptide Y in relation to posttraumatic stress symptoms in two combat cohorts

scientific article published on 19 February 2018

Biomarkers of PTSD: neuropeptides and immune signaling

scientific article published on 22 March 2011

Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study

scientific article

Blood-based gene-expression predictors of PTSD risk and resilience among deployed marines: a pilot study

scientific article

COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma

scientific article

CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study ⬇️

scientific article published on October 21, 2011

Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults

scientific article

Characterization of Cerebrospinal Fluid (CSF) and Plasma NPY Levels in Normal Volunteers over a 24-h Timeframe

article

Characterization of cerebrospinal fluid (CSF) and plasma NPY levels in normal volunteers over a 24-h timeframe

scientific article published on 10 June 2013

Chip-based direct genotyping of coding variants in genome wide association studies: utility, issues and prospects

scientific article published on 09 February 2014

Chromogranin A regulates renal function by triggering Weibel-Palade body exocytosis

scientific article published on 11 June 2009

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

scientific article published on 16 November 2018

Circadian polymorphisms associated with affective disorders.

scientific article published on 23 January 2009

Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles

scientific article

Common charge-shift mutation Glu65Lys in K+ channel β₁-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease

scientific article

Common genetic variants in ARNTL and NPAS2 and at chromosome 12p13 are associated with objectively measured sleep traits in the elderly

scientific article published on March 2013

Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levels

scientific article published on 23 January 2013

Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study

scientific article published on 21 September 2007

Comparison of genetic distance measures using human SNP genotype data

scientific article

Comparison of the genetic variation of captive ring-tailed lemurs with a wild population in Madagascar

scientific article

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry

scientific article published on 13 November 2018

Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines.

scientific article

Critical evaluation of copy number variant calling methods using DNA methylation

scientific article published on 18 November 2019

Delayed sleep phase cases and controls

scientific article

Delayed sleep phase syndrome is related to seasonal affective disorder.

scientific article

Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics

article

Diagnostic Utility of the Posttraumatic Stress Disorder (PTSD) Checklist for Identifying Full and Partial PTSD in Active-Duty Military

scientific article

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

scientific article published on 28 October 2015

Dissecting the genetic association of C-reactive protein with PTSD, traumatic events, and social support

scientific article published on 16 March 2020

Dopamine D1 receptor (DRD1) genetic polymorphism: pleiotropic effects on heritable renal traits

scientific article

Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

scientific article

Economic status mediates the relationship between educational attainment and posttraumatic stress disorder: a multivariable Mendelian randomization study: Supplemental Material

Effects of military service and deployment on clinical symptomatology: The role of trauma exposure and social support

scientific article published on 19 August 2017

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

scientific article published on 29 November 2018

Energy Intake During Reproduction in Captive Common Marmosets (Callithrix jacchus)

article

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

scientific article published on 3 January 2012

Entrainment of Circadian Rhythms to Temperature Reveals Amplitude Deficits in Fibroblasts from Patients with Bipolar Disorder and Possible Links to Calcium Channels

scientific article published on 04 April 2019

Epigenetic meta-analysis across three civilian cohorts identifies NRG1 and HGS as blood-based biomarkers for post-traumatic stress disorder

journal article published in 2018

Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline

journal article published in 2017

Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

scientific article published on 24 November 2020

Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress

scientific article published in 2022

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

scientific article published in Nature

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article published on 2 August 2017

Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin

scientific article published on 4 October 2012

Examination of the clock gene Cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association

scientific article

FMR1, circadian genes and depression: suggestive associations or false discovery?

scientific article published on 23 March 2013

Fear learning alterations after traumatic brain injury and their role in development of posttraumatic stress symptoms

scientific article published on 10 May 2017

Female veterans of the OEF/OIF conflict: concordance of PTSD symptoms and substance misuse

scientific article

Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder.

scientific article

Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation

scientific article published in December 2007

Further evidence for linkage of bipolar disorder to chromosomes 6 and 17 in a new independent pedigree series

scientific article published on February 2012

G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions

scientific article published on January 2009

Gene networks specific for innate immunity define post-traumatic stress disorder.

scientific article

Generalized analysis of molecular variance

scientific article

Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure

scientific article

Genetic Analysis of Group Composition and Breeding System in a Wild Common Marmoset (Callithrix jacchus) Population

Genetic analysis of hybridization and introgression between wild mongoose and brown lemurs

scientific article (publication date: 5 February 2009)

Genetic implication of a novel thiamine transporter in human hypertension

scientific article

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic variability and phylogeography in the wild Alaotran gentle lemur population

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

scientific article published on 21 January 2016

Genetic variants associated with sleep disorders

scientific article

Genetic variation at the delta-sarcoglycan (SGCD) locus elevates heritable sympathetic nerve activity in human twin pairs

scientific article published on 19 July 2013

Genetic vulnerability to DUSP22 promoter hypermethylation is involved in the relation between in utero famine exposure and schizophrenia

scientific article published on 21 August 2018

Genetically determined ancestry is more informative than self-reported race in HIV-infected and -exposed children

scientific article (publication date: September 2016)

Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder

scientific article

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

scientific article published on 11 May 2016

Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study

scientific article published on 09 October 2019

Genome-wide analyses of psychological resilience in U.S. Army soldiers

scientific article published on 13 May 2019

Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes

scientific journal article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

scientific article

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

article

Genome-wide association study of bipolar disorder in European American and African American individuals

scientific article

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

scientific article published on 20 June 2017

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.

scientific article published on 25 September 2012

Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative

scientific article published on 2 February 2018

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic influences on self-reported childhood maltreatment

scientific article published on 27 January 2020

Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene

scientific article

Group encounters and territoriality in wild Alaotran gentle lemurs (Hapalemur griseus alaotrensis).

scientific article published on January 1998

HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES.

scientific article

Heart rate variability characteristics in a large group of active-duty marines and relationship to posttraumatic stress

scientific article

Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoarding.

scientific article published in March 2007

Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study

scientific article published on 7 May 2015

Heritable influence of DBH on adrenergic and renal function: twin and disease studies

scientific article

Histopathology of pediatric nonalcoholic fatty liver disease.

scientific article

Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]

scientific article published on 16 October 2013

Identification of novel loci affecting circulating chromogranins and related peptides.

scientific article

Inference of human continental origin and admixture proportions using a highly discriminative ancestry informative 41-SNP panel

scientific article published on July 2013

Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults

scientific article published on 26 February 2009

Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome

scientific article

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

Large-scale integration of human genetic and physical maps

scientific article

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

scientific article published on 25 April 2017

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Letter to the Editor: Posttraumatic stress disorder has genetic overlap with cardiometabolic traits.

scientific article published on 4 April 2017

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

scientific article

Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder

scientific article published on 13 January 2020

Loss of GSTM1, a NRF2 target, is associated with accelerated progression of hypertensive kidney disease in the African American Study of Kidney Disease (AASK).

scientific article

M93. No Association Between COMT Val158Met and Prepulse Inhibition: Findings From the Marine Resiliency Study.

scientific article published on 20 March 2017

Matrix metalloproteinase haplotypes associated with coronary artery aneurysm formation in patients with Kawasaki disease

scientific article

Measuring novel antecedents of mental illness: the Questionnaire of Unpredictability in Childhood

scientific article published on 23 November 2018

MicroRNAs in Post-traumatic Stress Disorder

scientific article

Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3'-Untranslated Region Polymorphism C+87T by MicroRNA-107

scientific article published on 12 November 2014

Molecular genetic overlap between posttraumatic stress disorder and sleep phenotypes

scientific article published on 5 December 2019

NPY

Naturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease.

scientific article

Neuroepigenetics of Post-Traumatic Stress Disorder

scientific article published on 29 May 2018

Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses

scientific article published on 26 September 2012

New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility

scientific article

Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry

scientific article published on 24 September 2020

O4.1. GENETIC VULNERABILITY TO DUSP22 PROMOTOR HYPERMETHYLATION IS INVOLVED IN THE RELATION BETWEEN IN UTERO FAMINE EXPOSURE AND SCHIZOPHRENIA.

scientific article published in April 2018

PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study.

scientific article

PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways Across Biological Sex and Modes of Trauma.

scientific article published on 19 September 2017

Paraoxonase 1 (PON1) C/T-108 association with longitudinal mean arterial blood pressure

scientific article

Paternally inherited cis-regulatory structural variants are associated with autism.

scientific article published in April 2018

Peptide YY (PYY) Gene Polymorphisms in the 3'-Untranslated Region and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndrome Traits in Vivo

scientific article published on 01 December 2009

Peptide YY (PYY) Gene Polymorphisms in the 3′-Untranslated Region and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndrome Traits in Vivo.

scientific article published in October 2009

Peptide YY (PYY) Gene Polymorphisms in the 3′-Untranslated Region and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndrome Traits in Vivo.

scientific article published in December 2009

Peptide YY (PYY) gene polymorphisms in the 3'-untranslated and proximal promoter regions regulate cellular gene expression and PYY secretion and metabolic syndrome traits in vivo

scientific article published on 09 October 2009

Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system

scientific article

Polymorphisms in melatonin synthesis pathways: possible influences on depression

scientific article

Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study

scientific article

Post-traumatic stress disorder

scientific article published on 08 October 2015

Post-traumatic stress disorder: emerging concepts of pharmacotherapy

scientific article

Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations

scientific article published on 09 April 2019

Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency Study.

scientific article

Prevalence of suicidal ideation and other suicide warning signs in veterans attending an urgent care psychiatric clinic

scientific article published on 16 September 2014

Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.

scientific article published on 30 October 2017

Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis.

scientific article

Prospective assessment of psychophysiological risk factors for PTSD

article

Psychiatric Genomics: An Update and an Agenda

scientific article published on 3 October 2017

Psychiatric Genomics: An Update and an Agenda

Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

correction of a scholarly article

Rationale and Design of the Genetic Contribution to Drug Induced Renal Injury (DIRECT) Study

scientific article published on 24 August 2016

Restricted ethnic diversity in human embryonic stem cell lines

scientific article published on January 2010

Single nucleotide polymorphisms and haplotypes in Native American populations

scientific article

Singleton deletions throughout the genome increase risk of bipolar disorder

scientific article published on 30 December 2008

Sleep disturbance at pre-deployment is a significant predictor of post-deployment re-experiencing symptoms

scientific article published on 29 October 2019

Social system of the Alaotran gentle lemur (Hapalemur griseus alaotrensis): genetic characterization of group composition and mating system

scientific article published on August 2002

Successful treatment of post-traumatic stress disorder reverses DNA methylation marks

scientific article published on 23 October 2019

Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder

scientific article published on April 2006

Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families

scientific article published on April 2008

Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease

article

The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample

scientific article

The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration

scientific article

The association between lithium use and neurocognitive performance in patients with bipolar disorder

scientific article published on 29 April 2020

The catecholamine biosynthetic enzyme dopamine β-hydroxylase (DBH): first genome-wide search positions trait-determining variants acting additively in the proximal promoter.

scientific article

The cumulative effect of different childhood trauma types on self-reported symptoms of adult male depression and PTSD, substance abuse and health-related quality of life in a large active-duty military cohort

scientific article published on 4 August 2014

The resilience framework as a strategy to combat stress-related disorders

scientific article published on 16 October 2017

The role of emotional numbing in sexual functioning among veterans of the Iraq and Afghanistan wars

scientific article published in June 2010

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

scientific article published on 16 September 2016

Tracing sub-structure in the European American population with PCA-informative markers

scientific article

Traumatic stress and accelerated DNA methylation age: A meta-analysis.

scientific article published on 27 December 2017

Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population

scientific article

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