List of works - Jennifer L. Moran

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A family-based study of common polygenic variation and risk of schizophrenia

scientific article published on 12 April 2011

A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype

scientific article

A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability.

scientific article published on 25 September 2013

A humanized anti-CD3 antibody, HuM291, with low mitogenic activity, mediates complete and reversible T-cell depletion in chimpanzees

scientific article published on August 1999

A mouse model of Waardenburg syndrome type IV resulting from an ENU-induced mutation in endothelin 3

article

A mouse mutation in the 12R-lipoxygenase, Alox12b, disrupts formation of the epidermal permeability barrier

scientific article published in 2007

A polygenic burden of rare disruptive mutations in schizophrenia

scientific article

A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis

scientific article

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

scientific article published on 14 June 2009

An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15.

scientific article published on 23 April 2009

Analysis of copy number variations at 15 schizophrenia-associated loci.

scientific article published on 05 December 2013

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.

scientific article published on 21 July 2015

Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample

scientific article

Association at SYNE1 in both bipolar disorder and recurrent major depression

scientific article

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype

scientific article published in December 2008

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

scientific article

Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo

scientific article (publication date: September 2011)

Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder.

scientific article published on 31 July 2012

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

scientific article

Common alleles contribute to schizophrenia in CNV carriers

Common alleles contribute to schizophrenia in CNV carriers.

scientific article published on 22 September 2015

Common risk variants identified in autism spectrum disorder

Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Copy number variation in bipolar disorder

scientific article published on 06 January 2015

Copy number variation in schizophrenia in Sweden

scientific article

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

scientific article

De novo CNVs in bipolar affective disorder and schizophrenia

scientific article

De novo exon duplication in a new allele of mouse Glra1 (spasmodic)

scientific article

De novo mutations in schizophrenia implicate synaptic networks

scientific article

Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations

scientific article published on 8 September 2006

Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample.

scientific article published on 13 August 2013

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

scholarly article published 3 June 2017

Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth

scientific article

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

ENU mutagenesis in mice identifies candidate genes for hypogonadism

scientific article

ERG measurements of the spectral sensitivity of common chimpanzee (Pan troglodytes).

scientific article published in August 1996

Erratum: Common alleles contribute to schizophrenia in CNV carriers

scholarly article published in Molecular Psychiatry

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

scientific article

Evidence of Common Genetic Overlap Between Schizophrenia and Cognition.

scientific article published on 16 December 2015

Evidence that duplications of 22q11.2 protect against schizophrenia

scientific article

Exome Sequencing of Familial Bipolar Disorder

scientific article

Exome arrays capture polygenic rare variant contributions to schizophrenia.

scientific article published on 5 January 2016

Exome sequencing and the genetic basis of complex traits

scientific article published on 29 May 2012

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

scientific article published on 20 May 2012

Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse

scientific article

Gene expression changes during mouse skeletal myoblast differentiation revealed by transcriptional profiling.

scientific article published on 14 August 2002

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency

scientific article published on 22 October 2007

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

scientific article published on 27 October 2015

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

scientific article published on 14 February 2017

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

scientific journal article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

scientific article published on 9 August 2016

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

scientific article published on 24 October 2017

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

scientific article published on 12 July 2016

Genome-wide identification of mouse congenital heart disease loci

scientific article

Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type

scientific article published on 29 August 2017

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.

scientific article

Identification of common genetic risk variants for autism spectrum disorder

scientific article published on 25 February 2019

Implication of a rare deletion at distal 16p11.2 in schizophrenia

scientific article published on March 2013

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

scientific article published on 03 October 2016

Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice

scientific article

Limbs move beyond the Radical fringe

scientific article published on 01 June 1999

Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

scientific article published on July 2009

Mosaic copy number variation in schizophrenia

scientific article

Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia

scientific article

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

scientific article

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

scientific article

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach

scientific article published on 22 February 2016

Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus

scientific article

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample

scientific article published on 16 October 2012

Rescue of the mouse DDK syndrome by parent-of-origin-dependent modifiers

scientific article published on 18 October 2006

Screening for novel risk factors related to peripherally inserted central catheter-associated complications

scientific article published on 09 June 2014

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking

scientific journal article

The genomic psychiatry cohort: partners in discovery

scientific article published on 03 May 2013

The mouse Spam1 maps to proximal chromosome 6 and is a candidate for the sperm dysfunction in Rb(6.16)24Lub and Rb(6.15)1Ald heterozygotes

scientific article published in February 1997

The penetrance of copy number variations for schizophrenia and developmental delay.

scientific article

Three loci on mouse chromosome 5 and 10 modulate sex determination in XXOds/+ mice

scientific article published on 01 July 2007

Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse

scientific article

zCall: a rare variant caller for array-based genotyping: genetics and population analysis

scientific article

List of works by Jennifer L. Moran

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A family-based study of common polygenic variation and risk of schizophrenia

A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype

A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability.

A humanized anti-CD3 antibody, HuM291, with low mitogenic activity, mediates complete and reversible T-cell depletion in chimpanzees

A mouse model of Waardenburg syndrome type IV resulting from an ENU-induced mutation in endothelin 3

A mouse mutation in the 12R-lipoxygenase, Alox12b, disrupts formation of the epidermal permeability barrier

A polygenic burden of rare disruptive mutations in schizophrenia

A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15.

Analysis of copy number variations at 15 schizophrenia-associated loci.

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.

Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample

Association at SYNE1 in both bipolar disorder and recurrent major depression

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo

Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder.

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

Common alleles contribute to schizophrenia in CNV carriers

Common alleles contribute to schizophrenia in CNV carriers.

Common risk variants identified in autism spectrum disorder

Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Copy number variation in bipolar disorder

Copy number variation in schizophrenia in Sweden

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

De novo CNVs in bipolar affective disorder and schizophrenia

De novo exon duplication in a new allele of mouse Glra1 (spasmodic)

De novo mutations in schizophrenia implicate synaptic networks

Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations

Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample.

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ENU mutagenesis in mice identifies candidate genes for hypogonadism

ERG measurements of the spectral sensitivity of common chimpanzee (Pan troglodytes).

Erratum: Common alleles contribute to schizophrenia in CNV carriers

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

Evidence of Common Genetic Overlap Between Schizophrenia and Cognition.

Evidence that duplications of 22q11.2 protect against schizophrenia

Exome Sequencing of Familial Bipolar Disorder

Exome arrays capture polygenic rare variant contributions to schizophrenia.

Exome sequencing and the genetic basis of complex traits

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse

Gene expression changes during mouse skeletal myoblast differentiation revealed by transcriptional profiling.

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

Genome-wide identification of mouse congenital heart disease loci

Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.

Identification of common genetic risk variants for autism spectrum disorder

Implication of a rare deletion at distal 16p11.2 in schizophrenia

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice

Limbs move beyond the Radical fringe

Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

Mosaic copy number variation in schizophrenia

Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach

Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample

Rescue of the mouse DDK syndrome by parent-of-origin-dependent modifiers

Screening for novel risk factors related to peripherally inserted central catheter-associated complications

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking

The genomic psychiatry cohort: partners in discovery