List of works by Michael R. Barnes

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.

scientific article

A COMT gene haplotype associated with methamphetamine abuse.

scientific article

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

A short primer on the functional analysis of copy number variation for biomedical scientists

scientific article published on January 2010

ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation

scientific article published on 15 January 2011

Advances in blood pressure genomics

scientific article published on May 2013

An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection

scientific article

Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation

scientific article

Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma

article

Bioinformatics for dermatology - why we should learn about code.

scientific article published on 23 December 2017

C20orf9-003 (ACI-1), a gene localized on chromosome 20q13.12 encoding for a 49 kD cytoplasmic protein with a putative nucleotide binding site

scientific article

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

scientific article

Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery

scientific article

Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes

scientific article published on 12 April 2012

Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.

scientific article published on 16 November 2017

Correlation of protein and gene expression profiles of inflammatory proteins after endotoxin challenge in human subjects.

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Disruption of the neurexin 1 gene is associated with schizophrenia

scientific article

Drug discovery in the extracellular matrix

scientific article published on 24 June 2008

Enhanced Energetic State and Protection from Oxidative Stress in Human Myoblasts Overexpressing BMI1.

scientific article

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

scientific article published on 06 August 2021

Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates

scientific article published on 18 September 2020

Erratum: Whole-genome sequence-based analysis of thyroid function

scientific article published on 20 May 2015

Establishing an Academic–Industrial Stratified Medicine Consortium: Psoriasis Stratification to Optimize Relevant Therapy

scientific article published on 01 December 2015

Evaluation of splenic switch off in a tertiary imaging centre: validation and assessment of utility

scientific article published on 06 October 2016

Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

scientific article published on 06 February 2015

Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland

article

Feasibility of real-time capture of routine clinical data in the electronic health record: a hospital-based, observational service-evaluation study.

scientific article published on 8 March 2018

Frizzled proteins constitute a novel family of G protein-coupled receptors, most closely related to the secretin family

scientific article published on 01 October 1998

FrzB-2: a human secreted frizzled-related protein with a potential role in chondrocyte apoptosis.

scientific article

Gene Ranking of RNA-Seq Data via Discriminant Non-Negative Matrix Factorization.

scientific article

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

scientific article published on 17 December 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic variation analysis for biomedical researchers: a primer

scientific article published on January 2010

Genome-wide association analysis of copy number variation in recurrent depressive disorder.

scientific article

Genome-wide association study of major recurrent depression in the U.K. population.

scientific article published in June 2010

Genome-wide pharmacogenetics of antidepressant response in the GENDEP project

scientific article

Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

scientific article

Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualization of genome wide association studies

scientific article

Health and population effects of rare gene knockouts in adult humans with related parents

scientific article

Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design

scientific article published on 5 August 2016

IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty

scientific article

Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity

scientific article published on 01 January 2002

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

scientific article

Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery

scientific article published on 17 July 2009

M3C: Monte Carlo reference-based consensus clustering

scientific article published on 04 February 2020

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

scientific article

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Navigating the HapMap

scientific article published on 28 July 2006

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

scientific article published on 13 March 2009

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

scientific article

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder

scientific article

Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.

scientific article published on 25 October 2007

Precision phenotyping, panomics, and system-level bioinformatics to delineate complex biologies of atherosclerosis: rationale and design of the "Genetic Loci and the Burden of Atherosclerotic Lesions" study

scientific article published on 6 September 2014

Psychiatric genetics in silico: databases and tools for psychiatric geneticists

scientific article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

RNA sequencing and machine learning as molecular scalpels

scientific article published on 01 July 2018

Reply to Rational drug repositioning by medical genetics

scientific article published in December 2013

Research Techniques Made Simple: Bioinformatics for Genome-Scale Biology

scientific article published on September 2017

Risk in drug trials

scientific article published in The Lancet

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

scientific article published on 19 May 2022

Role for WNT16B in human epidermal keratinocyte proliferation and differentiation

scientific article

Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment

scientific article published on 20 September 2016

SNP and mutation data on the web - hidden treasures for uncovering

scientific article

Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study

scientific article published on 17 July 2017

Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo

scientific article published on 15 October 2015

Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants.

scientific article

Specific loss of connexin 26 expression in ductal sweat gland epithelium associated with the deletion mutation del(GJB6-D13S1830).

scientific article published in November 2005

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

scientific article published on 05 December 2019

The RA-MAP Consortium: a working model for academia-industry collaboration. ⬇️

scientific article published on 7 December 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression

scientific article published on September 2007

Tissue restricted expression of two human Frzbs in preadipocytes and pancreas

scientific article

Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia

scientific article published on 27 April 2011

Two variants of the C-reactive protein gene are associated with risk of pre-eclampsia in an American Indian population

scientific article

Use of genome-wide association studies for drug repositioning

Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis

scientific article (publication date: 27 April 2011)

Whole-genome sequence-based analysis of thyroid function.

scientific article

visxhclust: An R Shiny package for visual exploration of hierarchical clustering

scientific article published on 05 February 2022

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