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List of works by Emmanuelle M. Six

A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors

scientific article published on 11 June 2021

A combination of cyclophosphamide and interleukin-2 allows CD4+ T cells converted to Tregs to control scurfy syndrome

scientific article published on 01 April 2021

A human postnatal lymphoid progenitor capable of circulating and seeding the thymus

scientific article

A modified γ-retrovirus vector for X-linked severe combined immunodeficiency

scientific article

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

scientific article

Cytokines and culture medium have a major impact on human in vitro T-cell differentiation

scientific article published on 29 April 2011

Dynamics of Thymus-Colonizing Cells during Human Development

article

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

scientific article (publication date: 14 September 2001)

Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?

scientific article

Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination

scientific article published on 4 April 2013

HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor

article

Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice

scientific article published on August 2012

Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness

scientific article

Human and murine amniotic fluid c-Kit+Lin- cells display hematopoietic activity

scientific article published on 12 February 2009

Human hematopoiesis: from CD34 cells to T lymphocytes

scientific article published in February 2007

INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes

scientific article

INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions.

scientific article published on 18 December 2016

In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects.

scientific article published in March 2005

Les ligands Delta et la niche du développement lymphoïde

scientific article published on 01 January 2007

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome

scientific article published on 24 January 2022

Lymphoid-affiliated genes are associated with active histone modifications in human hematopoietic stem cells

scientific article published on 14 July 2008

Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor

scientific article published on July 2004

Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation.

scientific article published on 9 September 2010

Occurrence of myelodysplastic syndrome in 2 patients with reticular dysgenesis

scientific article published on 31 March 2011

Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome

scientific article published on April 2015

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement

scientific article

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement

Shortening the immunodeficient period after hematopoietic stem cell transplantation

scientific article

Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4<sup>+</sup> T cell perturbations

scientific article published on 08 April 2021

Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells.

scientific article published on 21 November 2017

The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase

scientific article

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity

scientific journal article

The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration.

scientific article

The putative pore-forming domain of Bax regulates mitochondrial localization and interaction with Bcl-X(L).

scientific article

Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction

scientific article published on 08 November 2021

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