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List of works by Mete Civelek

A Smoking-Associated miRNA-mRNA Coexpression Network

scientific article published in October 2017

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism

scientific article published in May 2018

A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel.

scientific article

A plasma proteogenomic signature for fibromuscular dysplasia

scientific article published on 01 January 2020

A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

scientific article published on 01 May 2021

A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein

scientific article published in Scientific Reports

Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits

scientific article published on 26 September 2019

Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes

scientific article

Assessing exposure effects on gene expression

scientific article published on 08 June 2020

Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.

scientific article published on 04 April 2013

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

scientific article published in Nature Communications

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

article

BART: a transcription factor prediction tool with query gene sets or epigenomic profiles

scientific article published on 28 March 2018

BART: a transcription factor prediction tool with query gene sets or epigenomic profiles

article

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

scientific article published on 20 July 2016

Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis.

scientific article published on 6 August 2009

Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution

scientific article published on 01 December 2019

Conducting the metabolic syndrome orchestra

scientific article published on June 2011

Coronary artery endothelial transcriptome in vivo: identification of endoplasmic reticulum stress and enhanced reactive oxygen species by gene connectivity network analysis

scientific article

Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

scientific article published on 2 March 2016

Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease

scientific article published on 3 March 2016

Defining data-driven primary transcript annotations with primaryTranscriptAnnotation in R

scientific article published on 09 January 2020

Discovery approaches to UPR in athero-susceptible endothelium in vivo.

scientific article published on January 2011

Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction

scientific article published on 08 August 2019

Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice

scientific journal article

Endoplasmic reticulum stress, redox, and a proinflammatory environment in athero-susceptible endothelium in vivo at sites of complex hemodynamic shear stress

scientific article

Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

scientific article

Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo

scientific article published on April 2010

Epigenome-wide association in adipose tissue from the METSIM cohort

scientific article published on 16 March 2018

Epigenome-wide association in adipose tissue from the METSIM cohort.

scientific article published in July 2018

Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling

scientific article published on 01 August 2020

From hairballs to an understanding of transendothelial migration of monocytes in atherosclerosis

scientific article published on September 2014

Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus

scientific article

Genes in human obesity loci are causal obesity genes in C. elegans

scientific article published on 07 September 2021

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

scientific article (publication date: December 2015)

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

scientific article

Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells

scientific article published on 12 October 2020

Genetic Regulation of enoyl-CoA hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans

scientific article published on 22 April 2019

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.

scientific article published in July 2015

Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice

scientific article

Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits

scientific article published on 04 April 2013

Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics

article published in the Proceedings of the National Academy of Sciences of the United States of America

Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways

scientific article

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

scientific article

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

scientific article

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

scientific article

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells

scientific article

Identification of breast cancer associated variants that modulate transcription factor binding.

scientific article published on 28 September 2017

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.

scientific article

Integrative approaches for large-scale transcriptome-wide association studies

scientific article published on 8 February 2016

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

scientific article

Intracellular calcium changes in rat aortic smooth muscle cells in response to fluid flow

scientific article published on March 2002

Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets

scientific article published on 23 July 2020

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces

scientific article

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

scientific article

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro.

scientific article

MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor

scientific article

MicroRNAs and regulation of cardiometabolic phenotypes: novel insights into the complexity of genome-wide association studies loci

scientific article published on 01 September 2019

Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol

scientific article

Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.

scientific article

Obesity-linked suppression of membrane-bound -acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

scientific article published on 17 October 2019

Prediction of Causal Candidate Genes in Coronary Artery Disease Loci

scientific article

Prelesional arterial endothelial phenotypes in hypercholesterolemia: universal ABCA1 upregulation contrasts with region-specific gene expression in vivo

scientific article

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans

scientific article

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Regulation of NF-κB signaling by oxidized glycerophospholipid and IL-1β induced miRs-21-3p and -27a-5p in human aortic endothelial cells

scientific article

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

scientific article

Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function

scientific article published on 30 September 2016

SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes

scientific article

Scavenger receptor class A member 5 (SCARA5) and suprabasin (SBSN) are hub genes of coexpression network modules associated with peripheral vein graft patency

scientific article

Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis

scientific article published on 23 September 2020

Smooth muscle cells contract in response to fluid flow via a Ca2+-independent signaling mechanism

scientific article published on 30 August 2002

Systems genetics approaches to understand complex traits

scientific article published on 03 December 2013

The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1

scientific article published on 10 September 2019

The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes

article

The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

scientific article published on 28 August 2020

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits

scientific article

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

scientific article published in June 2017

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.

scientific article

The WWOX gene modulates high-density lipoprotein and lipid metabolism

scientific article

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo

scientific article published on 25 April 2013

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

scientific article

Transcription Factor KLF14 and Metabolic Syndrome

scientific article published on 27 May 2020

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA.

scientific article published on 12 February 2018