List of works by Honghuang Lin

A comparison of whole genome sequencing with exome sequencing for family-based association studies

scientific article published on 17 June 2014

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker

scientific article

A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking

scientific article

Advances in Exploration of Machine Learning Methods for Predicting Functional Class and Interaction Profiles of Proteins and Peptides Irrespective of Sequence Homology

scholarly article by Juan Cui et al published 1 May 2007 in Current Bioinformatics

Assessment of the Mid-Life Demographic and Lifestyle Risk Factors of Dementia Using Data from the Framingham Heart Study Offspring Cohort

scientific article published on 01 January 2018

Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study

article published in 2019

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Association of Genetic Variation in Coronary Artery Disease-Related Loci With the Risk of Heart Failure With Preserved Versus Reduced Ejection Fraction

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α.

scientific article

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

scientific article

Association of genetic variations and gene expression in a family-based study

scientific article

Atrial fibrillation: current knowledge and future directions in epidemiology and genomics

scientific article published on November 2011

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automatic synchronization and distribution of biological databases and software over low-bandwidth networks among developing countries.

scientific article

Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction

scientific article published on 01 May 2018

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling

scientific article published on 03 September 2013

Comparing Bowtie and BWA to Align Short Reads from a RNA-Seq Experiment

scholarly article by N. Medina-Medina et al published 2012 in Advances in Intelligent and Soft Computing

Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design

scientific article published on 30 September 2019

Computer prediction of drug resistance mutations in proteins.

scientific article

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Cross-sectional relations of whole-blood miRNA expression levels and hand grip strength in a community sample

scientific article published on 08 June 2017

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

Dana-Farber repository for machine learning in immunology

scientific article published on 18 July 2011

Deep learning enables genetic analysis of the human thoracic aorta

scientific article published on 26 November 2021

Derivation of stable microarray cancer-differentiating signatures using consensus scoring of multiple random sampling and gene-ranking consistency evaluation.

scientific article published on October 2007

Diminished PRRX1 Expression Is Associated With Increased Risk of Atrial Fibrillation and Shortening of the Cardiac Action Potential

scientific article

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Efficacy of different protein descriptors in predicting protein functional families.

scientific article

Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation

scientific article published on 06 November 2020

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study.

scientific article published on 24 April 2018

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article published in July 2017

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Exploring the Hierarchical Influence of Cognitive Functions for Alzheimer Disease: The Framingham Heart Study

scientific article published on 23 April 2020

Familial clustering of hypertensive target organ damage in the community

scientific article published on 23 January 2018

Functional analysis of HapMap SNPs

scientific article published on 4 October 2012

Gain-of-function mutations in GATA6 lead to atrial fibrillation

scientific journal article

Gene expression and genetic variation in human atria

scientific article published on 28 October 2013

Gene expression markers of age-related inflammation in two human cohorts

scientific article

Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons

scientific article

Gene-gene Interaction Analyses for Atrial Fibrillation

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

article published in 2018

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

scientific article published on 21 August 2020

Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization

scientific article published on 14 December 2016

Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation.

scientific article published on 12 November 2017

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

scientific article published on 22 September 2020

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study

scientific article published on 5 January 2015

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study for endothelial growth factors

scientific article published on 31 December 2014

Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study

scientific article (publication date: February 2013)

Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes

scientific article

Genomic profiling by machine learning

scholarly article published November 2011

Healthy diet is associated with gene expression in blood: the Framingham Heart Study

scientific article published on 01 September 2019

Higher dietary anthocyanin and flavonol intakes are associated with anti-inflammatory effects in a population of US adults

scientific article published on 27 May 2015

Information of ADME-Associated Proteins and Potential Application for Pharmacogenetic Prediction of Drug Responses

article

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

scientific article published on 14 August 2014

Integrative Omics Approach to Identifying Genes Associated With Atrial Fibrillation

scientific article published on 05 December 2019

Integrative methylation score to identify epigenetic modifications associated with lipid changes resulting from fenofibrate treatment in families

scientific article published on 17 September 2018

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

scientific article published on 10 April 2017

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

MHC-BPS: MHC-binder prediction server for identifying peptides of flexible lengths from sequence-derived physicochemical properties.

scientific article published on 11 July 2006

Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study.

scientific article published on 25 July 2017

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

scientific article published on 29 April 2012

Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study).

scientific article published on 24 August 2016

Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study

scientific article

MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage.

scientific article published in October 2017

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ethnic genome-wide association study for atrial fibrillation

article

Mutation of a common amino acid in NKX2.5 results in dilated cardiomyopathy in two large families.

scientific article

Network Analysis of Depression-Related Transcriptomic Profiles

scientific article published on 01 March 2019

Next steps in cardiovascular disease genomic research--sequencing, epigenetics, and transcriptomics

scientific article published on 18 November 2011

Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy

scientific article published in December 2017

Novel Risk Modeling Approach of Atrial Fibrillation With Restricted Mean Survival Times: Application in the Framingham Heart Study Community-Based Cohort

scientific article published on 31 March 2020

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

scientific article published on 30 January 2014

PEARLS: Program for Energetic Analysis of Receptor−Ligand System

article

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study).

scientific article

Pleiotropic genes for metabolic syndrome and inflammation

scientific article

Prediction of MHC-binding peptides of flexible lengths from sequence-derived structural and physicochemical properties

scientific article published on 27 June 2006

Prediction of antibiotic resistance proteins from sequence-derived properties irrespective of sequence similarity

scientific article published on 25 June 2008

Prediction of factor Xa inhibitors by machine learning methods.

scientific article

Prediction of functional class of novel plant proteins by a statistical learning method.

scientific article published in October 2005

Prediction of the functional class of lipid binding proteins from sequence-derived properties irrespective of sequence similarity.

scientific article published on 27 January 2006

Prediction of transporter family from protein sequence by support vector machine approach.

scientific article

Prefrontal cortex eQTLs/mQTLs enriched in genetic variants associated with alcohol use disorder and other diseases

scientific article published on 04 June 2020

Protein Biomarkers and Risk of Atrial Fibrillation: The FHS

scientific article published on 15 January 2020

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Proteomic Signatures of Lifestyle Risk Factors for Cardiovascular Disease: A Cross-Sectional Analysis of the Plasma Proteome in the Framingham Heart Study

scientific article published on 29 December 2020

Proteomics Profiling and Risk of New‐Onset Atrial Fibrillation: Framingham Heart Study

scientific article published on 01 March 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project

article

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm

scientific article published on 19 November 2018

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare genetic variant analysis on blood pressure in related samples

scientific article published on 17 June 2014

Recent exposure to particle radioactivity and biomarkers of oxidative stress and inflammation: The Framingham Heart Study

scientific article published in 2018

Recent progresses in the application of machine learning approach for predicting protein functional class independent of sequence similarity

scientific article published on July 2006

Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study.

scientific article

Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study

scientific article published on 19 August 2020

Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke

scientific article

Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study

scientific article

Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis

scientific article published in 2023

Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Support vector machines approach for predicting druggable proteins: recent progress in its exploration and investigation of its usefulness.

scientific article published on 7 March 2007

TANTIGEN: a comprehensive database of tumor T cell antigens

scientific article

Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

scientific article (publication date: March 2014)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Tissue-specific Network Analysis of Genetic Variants Associated with Coronary Artery Disease

scientific article published in Scientific Reports

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Transcriptome-wide association study of inflammatory biologic age.

scientific article

Transcriptomic Heterogeneity of Alzheimer's Disease Associated with Lipid Genetic Risk

scientific article published on 29 August 2020

Validation of Polygenic Scores for QT Interval in Clinical Populations

scientific article published in October 2017

Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level

scientific article

Whole Blood Gene Expression Associated with Clinical Biological Age

article

Whole Exome Sequencing in Atrial Fibrillation

scientific article

Whole blood gene expression and atrial fibrillation: the Framingham Heart Study

scientific article

Whole blood gene expression and interleukin-6 levels

scientific article

Whole blood gene expression and white matter Hyperintensities.

scientific article published on 18 September 2017

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

scientific article published on 16 March 2017

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Paulina is supported by:

About Paulina

Help