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List of works by Yi-Cheng Chang

A genome-wide scan for circulating vascular adhesion protein-1 (VAP-1) levels: MACROD2 as a potential transcriptional regulator of adipogenesis

scientific article published on 24 January 2018

A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.

scientific article published on 08 October 2013

A triglyceride-raising APOA5 genetic variant is negatively associated with obesity and BMI in the Chinese population

scientific article published on 4 February 2010

ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients

scientific article published on 21 July 2019

Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway

scientific article

Adverse outcomes after noncardiac surgery in patients with diabetes: a nationwide population-based retrospective cohort study

scientific article published on 29 August 2013

Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of microenvironment associated with COPD

scientific article published on 01 July 2019

An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning

scientific article published on 19 February 2021

Anaemia and related nutrient deficiencies after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis

scientific article (publication date: 2015)

Association Study of the Genetic Polymorphisms of the Transcription Factor 7-Like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population

article

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.

scientific article

Association of intraocular pressure with the metabolic syndrome and novel cardiometabolic risk factors.

scientific article published on 9 October 2009

Association of obesity, diabetes, and risk of tuberculosis: two population-based cohorts

scientific article

Association of the variations in the HSD3β gene with primary aldosteronism

scientific article published in July 2013

BICD1 expression, as a potential biomarker for prognosis and predicting response to therapy in patients with glioblastomas

scientific article published on 27 November 2017

Cardiovascular risk associated with acarbose versus metformin as the first-line treatment in patients with type 2 diabetes: a nationwide cohort study

scientific article published on 2 January 2015

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption

scientific article

Common PCSK1 haplotypes are associated with obesity in the Chinese population

scientific article published on 29 October 2009

Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population

scientific article published on 16 May 2008

Cross-sectional validation of diabetes risk scores for predicting diabetes, metabolic syndrome, and chronic kidney disease in Taiwanese

scientific article published on 15 September 2009

Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human

scientific article published on 04 July 2013

Diabetes risks and outcomes in chronic obstructive pulmonary disease patients: Two nationwide population-based retrospective cohort studies

scientific article published on 16 August 2017

Different angiotensin receptor blockers and incidence of diabetes: a nationwide population-based cohort study

scientific article

Dipeptidyl Peptidase-4 Inhibitor Use Is Not Associated With Acute Pancreatitis in High-Risk Type 2 Diabetic Patients: A Nationwide Cohort Study

scientific article published on February 2016

Early Myocardial Repolarization Heterogeneity Is Detected by Magnetocardiography in Diabetic Patients with Cardiovascular Risk Factors

scientific article published on 17 July 2015

Early detection of diabetic kidney disease: Present limitations and future perspectives

scientific article

Effect of Sickle Cell Trait and <i>APOL1</i> Genotype on the Association of Soluble uPAR with Kidney Function Measures in Blacks

scientific article published on 02 December 2020

Enrichment of Aldolase C Correlates with Low Non-Mutated IDH1 Expression and Predicts a Favorable Prognosis in Glioblastomas

scientific article published on 23 August 2019

Erratum to: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

article

FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness

scientific article published on 28 November 2019

Follistatin-like Protein 1 Inhibits Lung Cancer Metastasis by Preventing Proteolytic Activation of Osteopontin

scientific article published on 25 October 2019

Genetic Variation in the Human SORBS1 Gene is Associated With Blood Pressure Regulation and Age at Onset of Hypertension: A SAPPHIRe Cohort Study

scientific article published in March 2016

Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

scientific article

Genetic polymorphisms of the angiotensin II type 1 receptor gene and diastolic heart failure

scientific article published in March 2009

Genetic predisposition and nongenetic risk factors of thiazolidinedione-related edema in patients with type 2 diabetes

scientific article published in December 2011

Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults.

scientific article

Genetic variation in the NOC gene is associated with body mass index in Chinese subjects

scientific article

Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

scientific article

Genetic variation of SORBS1 gene is associated with glucose homeostasis and age at onset of diabetes: A SAPPHIRe Cohort Study.

scientific article published on 12 July 2018

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Ghrelin Upregulates Oncogenic Aurora A to Promote Renal Cell Carcinoma Invasion

scientific article published on 04 March 2019

Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation

scientific article published on 21 March 2016

High TSH Level within Normal Range Is Associated with Obesity, Dyslipidemia, Hypertension, Inflammation, Hypercoagulability, and the Metabolic Syndrome: A Novel Cardiometabolic Marker

scientific article published on 07 June 2019

Identification of MALT1 as both a prognostic factor and a potential therapeutic target of regorafenib in cholangiocarcinoma patients.

scientific article published on 8 December 2017

Impact of Diabetes on Stroke Risk and Outcomes: Two Nationwide Retrospective Cohort Studies

scientific article published on December 2015

Increased diabetes risk and interaction with social and medical events in patients upon stroke: Two nationwide studies

scientific article

Increased risk of fracture and postfracture adverse events in patients with diabetes: two nationwide population-based retrospective cohort studies

scientific article published on 7 May 2014

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2

scientific article published on 28 January 2016

Interaction of ADIPOQ genetic polymorphism with blood pressure and plasma cholesterol level on the risk of coronary artery disease

scientific article published on 7 August 2009

Knockdown of RyR3 enhances adiponectin expression through an atf3-dependent pathway

scientific article published on February 6, 2013

Leptin signaling axis specifically associates with clinical prognosis and is multifunctional in regulating cancer progression.

scientific article published on 30 March 2018

Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy

scientific article published on 08 July 2013

Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease

scientific article

MART-10 represses cholangiocarcinoma cell growth and high vitamin D receptor expression indicates better prognosis for cholangiocarcinoma.

scientific article published on 3 March 2017

MTAP is an independent prognosis marker and the concordant loss of MTAP and p16 expression predicts short survival in non-small cell lung cancer patients

scientific article

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

scientific article

Mitochondrial DNA associations with East Asian metabolic syndrome

scientific article published on 08 July 2018

Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance

scientific article published on 10 September 2020

Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness

scientific article published on 18 March 2020

Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress

scientific article published on 2 February 2018

Omics-Based Platforms: Current Status and Potential Use for Cholangiocarcinoma

scientific article published on 28 September 2020

Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis

scientific article published on 10 October 2019

Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axis

scientific article published on 27 January 2020

Preoperative prediction of papillary thyroid carcinoma prognosis with the assistance of computerized morphometry of cytology samples obtained by fine-needle aspiration: preliminary report

scientific article published on 13 January 2012

Prostaglandin reductase 2 modulates ROS-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients

scientific article

Prostaglandin reductase-3 negatively modulates adipogenesis through regulation of PPARγ activity

scientific journal article

Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort

scientific article published in March 2012

Roles of Aldolase Family Genes in Human Cancers and Diseases

article

SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes

scientific article

Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis.

scientific article

Severe hepatic injury associated with different statins in patients with chronic liver disease: a nationwide population-based cohort study

scientific article published in January 2015

Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis

scientific article published on September 2014

Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway

scientific article published on 29 August 2020

Study design and recruitment for a prospective controlled study of diabesity: Taiwan Diabesity Study

scientific article published on 06 April 2018

Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study

scientific article published in February 2018

TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance

scientific article published on 6 October 2009

The Association Between Body Mass Index and the Risk of Hospitalization and Mortality due to Infection: A Prospective Cohort Study

scientific article published in January 2021

The Effects of Bariatric Surgery on Renal, Neurological, and Ophthalmic Complications in Patients with Type 2 Diabetes: the Taiwan Diabesity Study

scientific article published on 18 July 2020

The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment

scientific article

The associations of LPIN1 gene expression in adipose tissue with metabolic phenotypes in the Chinese population.

scientific article published on 18 June 2009

The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex I

scientific article published on 12 August 2016

The relationship of visfatin/pre-B-cell colony-enhancing factor/nicotinamide phosphoribosyltransferase in adipose tissue with inflammation, insulin resistance, and plasma lipids

scientific article published on 17 September 2009

The role of nocturnin in early adipogenesis and modulation of systemic insulin resistance in human

scientific article published on 14 February 2012

Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival

scientific article published on 29 July 2019

Validation of diabetes risk scores for predicting diabetes diagnosed by oral glucose tolerance test

scientific article published in February 2010

Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis

scientific article

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