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List of works by Yi-Cheng Chang

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

scientific article
Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population

scientific article published on 16 May 2008
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.

scientific article
Association Study of the Genetic Polymorphisms of the Transcription Factor 7-Like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population

article
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease

scientific article
Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway

scientific article
Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy

scientific article published on 08 July 2013
Increased risk of fracture and postfracture adverse events in patients with diabetes: two nationwide population-based retrospective cohort studies

scientific article published on 7 May 2014
The relationship of visfatin/pre-B-cell colony-enhancing factor/nicotinamide phosphoribosyltransferase in adipose tissue with inflammation, insulin resistance, and plasma lipids

scientific article published on 17 September 2009
Cross-sectional validation of diabetes risk scores for predicting diabetes, metabolic syndrome, and chronic kidney disease in Taiwanese

scientific article published on 15 September 2009
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.

scientific article published on 08 October 2013
Genetic polymorphisms of the angiotensin II type 1 receptor gene and diastolic heart failure

scientific article published in March 2009
Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults

scientific article
Anaemia and related nutrient deficiencies after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis

scientific article (publication date: 2015)
Common PCSK1 haplotypes are associated with obesity in the Chinese population

scientific article published on 29 October 2009
Adverse outcomes after noncardiac surgery in patients with diabetes: a nationwide population-based retrospective cohort study

scientific article published on 29 August 2013
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human

scientific article published on 04 July 2013
Association of intraocular pressure with the metabolic syndrome and novel cardiometabolic risk factors.

scientific article published on 9 October 2009
Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption

scientific article
Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis

scientific article
Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort

scientific article published in March 2012
Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis

scientific article published on September 2014
MTAP is an independent prognosis marker and the concordant loss of MTAP and p16 expression predicts short survival in non-small cell lung cancer patients

scientific article
Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation

scientific article published on 21 March 2016
Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis.

scientific article
Early detection of diabetic kidney disease: Present limitations and future perspectives

scientific article
Association of obesity, diabetes, and risk of tuberculosis: two population-based cohorts

scientific article
The associations of LPIN1 gene expression in adipose tissue with metabolic phenotypes in the Chinese population

scientific article published on 18 June 2009
Roles of Aldolase Family Genes in Human Cancers and Diseases

article
Diabetes risks and outcomes in chronic obstructive pulmonary disease patients: Two nationwide population-based retrospective cohort studies

scientific article published on 16 August 2017
TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance

scientific article published on 6 October 2009
Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2

scientific article published on 28 January 2016
Interaction of ADIPOQ genetic polymorphism with blood pressure and plasma cholesterol level on the risk of coronary artery disease

scientific article published on 7 August 2009
Genetic predisposition and nongenetic risk factors of thiazolidinedione-related edema in patients with type 2 diabetes

scientific article published in December 2011
Severe hepatic injury associated with different statins in patients with chronic liver disease: A nationwide population‐based cohort study

scientific article published on January 1, 2015
The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment

scientific article
Impact of Diabetes on Stroke Risk and Outcomes: Two Nationwide Retrospective Cohort Studies

scientific article published on December 2015
Genetic variation in the NOC gene is associated with body mass index in Chinese subjects

scientific article
The role of nocturnin in early adipogenesis and modulation of systemic insulin resistance in human

scientific article published on 14 February 2012
Dipeptidyl Peptidase-4 Inhibitor Use Is Not Associated With Acute Pancreatitis in High-Risk Type 2 Diabetic Patients

scientific article published on February 1, 2016
Cardiovascular risk associated with acarbose versus metformin as the first-line treatment in patients with type 2 diabetes: a nationwide cohort study

scientific article published on 2 January 2015
Different angiotensin receptor blockers and incidence of diabetes: a nationwide population-based cohort study

scientific article
The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex I

scientific article published on 12 August 2016
Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

scientific article
Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress

scientific article published on 2 February 2018
Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study

scientific article published in February 2018
Prostaglandin reductase 2 modulates ROS-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients

scientific article
Leptin signaling axis specifically associates with clinical prognosis and is multifunctional in regulating cancer progression.

scientific article published on 30 March 2018
Mitochondrial DNA associations with East Asian metabolic syndrome

scientific article published on 08 July 2018

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